公开(公告)号：US20170100603A1

公开(公告)日：2017-04-13

申请号：US15286901

申请日：2016-10-06

Applicant: Boston Scientific Scimed, Inc.

Inventor： Hong Cao ,  Martin R. Willard ,  Patrick A. Haverkost ,  Derek C. Sutermeister

IPC: A61N2/00 ,  A61K41/00 ,  A61K47/48 ,  A61K9/00

Abstract: The disclosure pertains to mixtures of LaFeSiH magnetic nanoparticles having different Curie temperatures useful for improved inductive hyperthermia efficiency, injectable formulations containing the nanoparticles, and methods of raising the temperature of selected cells using the nanoparticles.

公开(公告)号：US20160199661A1

公开(公告)日：2016-07-14

申请号：US14993735

申请日：2016-01-12

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Martin R. Willard ,  Derek C. Sutermeister

IPC: A61N1/40

CPC classification number: A61N1/40 ,  A61K9/0024 ,  A61L31/022 ,  A61L2400/12

Abstract: Systems, methods, and devices for treating cancer can produce field potentials of between 20 mV and 70 mV. In some cases, systems, methods, and devices provided herein can include a plurality of particles. The particles can include at least a first material and at least a second material, which can have electrode potentials configured to form a galvanic couple in the location of cancerous tissue to form a field potential adapted to preferentially target cancerous tissue over healthy tissue.

Abstract translation: 用于治疗癌症的系统，方法和装置可以产生20mV和70mV之间的场电位。 在一些情况下，本文提供的系统，方法和装置可以包括多个颗粒。 颗粒可以包括至少第一材料和至少第二材料，其可以具有配置成在癌组织的位置中形成电耦合的电极电位，以形成适于优先靶向健康组织上的癌组织的场电位。