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    Resettable drive mechanism for a drug delivery device with guide track and blocking means
    42.
    发明授权
    Resettable drive mechanism for a drug delivery device with guide track and blocking means 有权
    具有导轨和阻塞装置的药物输送装置的可复位驱动机构

    公开(公告)号：US09463278B2

    公开(公告)日：2016-10-11

    申请号：US13395701

    申请日：2010-09-29

    申请人： Catherine Anne MacDonald ,  Robert Veasey ,  Christopher Jones ,  Garen Kouyoumjian

    发明人： Catherine Anne MacDonald ,  Robert Veasey ,  Christopher Jones ,  Garen Kouyoumjian

    IPC分类号： A61M5/24 ,  A61M5/31 ,  A61M5/315

    CPC分类号： A61M5/24 ,  A61M5/3146 ,  A61M5/31543 ,  A61M5/31555 ,  A61M5/31556 ,  A61M5/3156 ,  A61M5/3158 ,  A61M2005/2407 ,  A61M2005/2488 ,  A61M2005/2492

    摘要： A resettable drive mechanism for a drug delivery device (1) comprises a piston rod assembly (32) and an interaction member (23). The piston rod assembly (32) comprises a guide track (18) running along the piston rod assembly (32), the guide track (18) comprising at least one delivery section (18A) and at least one reset section (18B). The reset section (18B) is arranged to continue the delivery section (18A). The delivery section (18A) comprises at least one blocking means (19). The interaction member (23) is configured to cooperate with the guide track (18). For delivering a dose of a drug (24), the piston rod assembly (32) is axially displaceable in a dose delivery direction away from an axial starting position, the interaction member (23) cooperating with the delivery section (18A) and the blocking means (19) passing the interaction member (23) when the piston rod assembly (32) is displaced in the dose delivery direction. Axial displacement of the piston rod assembly (32) towards the axial starting position is prevented by mechanical interaction of the blocking means (19) and the interaction member (23) when the interaction member (23) cooperates with the delivery section (18A). For resetting the drug delivery device (1), the interaction member (23) is configured to cooperate with the reset section (18B), the piston rod assembly (32) being axially displaced towards the axial starting position, the blocking means (19) being offset from the interaction member (23) and passing the axial position of the interaction member (23) when the piston rod assembly (32) is axially displaced towards the axial starting position. Also, a piston rod assembly (32) is proposed.

    摘要翻译： 用于药物输送装置（1）的可重置驱动机构包括活塞杆组件（32）和相互作用构件（23）。 活塞杆组件（32）包括沿着活塞杆组件（32）延伸的导轨（18），导轨（18）包括至少一个输送部分（18A）和至少一个复位部分（18B）。 复位部分（18B）布置成继续传送部分（18A）。 输送部分（18A）包括至少一个阻挡装置（19）。 相互作用构件（23）构造成与导轨（18）配合。 为了递送药物（24）的剂量，活塞杆组件（32）可以在远离轴向起始位置的剂量递送方向上轴向移位，相互作用构件（23）与输送段（18A）配合并阻塞 当活塞杆组件（32）在剂量递送方向上移位时，装置（19）使相互作用构件（23）通过。 当相互作用构件（23）与输送段（18A）配合时，通过阻挡装置（19）和相互作用构件（23）的机械相互作用来防止活塞杆组件（32）朝向轴向起始位置的轴向位移。 为了复位药物输送装置（1），相互作用构件（23）构造成与复位部分（18B）配合，活塞杆组件（32）朝着轴向起始位置轴向移位，阻挡装置（19） 当所述活塞杆组件（32）朝向所述轴向起始位置轴向移位时，所述相互作用构件（23）偏离所述相互作用构件（23）的轴向位置。 此外，提出了一种活塞杆组件（32）。

    DRUG DELIVERY DEVICE, ASSEMBLY FOR A DRUG DELIVERY DEVICE AND METHOD FOR SETTING UP A DRUG DELIVERY DEVICE
    44.
    发明申请
    DRUG DELIVERY DEVICE, ASSEMBLY FOR A DRUG DELIVERY DEVICE AND METHOD FOR SETTING UP A DRUG DELIVERY DEVICE 有权
    药物递送装置，用于药物递送装置的组装和用于设置药物递送装置的方法

    公开(公告)号：US20130030409A1

    公开(公告)日：2013-01-31

    申请号：US13497376

    申请日：2010-09-29

    申请人： Catherine Anne Macdonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Alexander Ian Bailey

    发明人： Catherine Anne Macdonald ,  Robert Veasey ,  Garen Kouyoumjian ,  Christopher Jones ,  Alexander Ian Bailey

    IPC分类号： A61M5/315

    CPC分类号： A61M5/24 ,  A61M5/2448 ,  A61M5/3146 ,  A61M5/31571 ,  A61M5/31578 ,  A61M2005/2073 ,  A61M2005/2451

    摘要： The instant application is directed to an assembly for a drug delivery device which is arranged to operate in two distinct modes, a priming mode starting from a pre-priming state and a dispense mode operating in a post-priming state, and a drug delivery device comprising this assembly. The assembly comprises a dose member, an actuating member and a piston rod which is configured to act on a bung of an assembled cartridge containing the drug. In the pre-priming state the actuating member is configured to be moved by a user such that the movement of the actuating member causes a movement of the dose member and such that the movement of the dose member causes a movement of the piston rod. In the post-priming state the dose member is configured to be moved by a user without causing a movement of the actuating member in order to perform a set and dispense action of the drug delivery device.

    摘要翻译： 本申请涉及用于药物递送装置的组件，其被布置成以两种不同模式操作，从预灌注状态开始的启动模式和以后启动状态操作的分配模式，以及药物递送装置 包括该组件。 组件包括剂量构件，致动构件和活塞杆，其构造成作用在装有药物的组装好的药筒的栓上。 在预灌注状态下，致动构件被构造成由使用者移动，使得致动构件的移动导致剂量构件的运动，并且使得剂量构件的移动导致活塞杆的移动。 在后启动状态中，剂量构件被构造成由使用者移动而不引起致动构件的移动，以便执行药物递送装置的集合和分配动作。

    Method and Assembly for a Drug Delivery Device
    45.
    发明申请
    Method and Assembly for a Drug Delivery Device 有权
    药物输送装置的方法和装配

    公开(公告)号：US20120289906A1

    公开(公告)日：2012-11-15

    申请号：US13496337

    申请日：2010-09-29

    申请人： Christopher Jones ,  Robert Veasey ,  Garen Kouyoumjian ,  Catherine Anne MacDonald ,  Michael Jugl ,  Gunther Sendatzki

    发明人： Christopher Jones ,  Robert Veasey ,  Garen Kouyoumjian ,  Catherine Anne MacDonald ,  Michael Jugl ,  Gunther Sendatzki

    IPC分类号： A61M5/00 ,  B23P11/00

    CPC分类号： A61M5/24 ,  A61M5/3146 ,  A61M5/31555 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/344 ,  A61M5/347 ,  A61M2005/2407 ,  A61M2005/2477 ,  A61M2005/2488 ,  A61M2205/6045 ,  A61M2207/00 ,  Y10T29/49826

    摘要： A method for securing a cartridge (4) in a cartridge holder (3) is provided, the method comprising the steps of inserting the cartridge (4) into the cartridge holder (3), the cartridge holder (3) having a proximal end and a distal end, axially displacing the cartridge (4) in a proximal direction with respect to the cartridge holder (3) from a distal initial position to a proximal end position and securing the cartridge (4) in the end position against displacement in the distal direction with respect to the cartridge holder (3). An assembly for a drug delivery device (1) is provided comprising a cartridge (4), an adjusting member (12, 25, 28, 34) and a cartridge holder (3). The cartridge holder (3) has a distal end and a proximal end. The adjusting member (12, 25, 28, 34) is secured to the cartridge holder (3). The adjusting member (12, 25, 28, 34) holds a distal portion of the cartridge (4) at a distance with respect to a distal portion of the cartridge holder (3).

    摘要翻译： 提供了一种用于将盒（4）固定在盒保持器（3）中的方法，所述方法包括以下步骤：将盒（4）插入盒保持器（3），盒保持器（3）具有近端和 一个远端，使药筒（4）相对于药筒保持器（3）的近端方向从远端初始位置轴向移位到近端位置，并将药筒（4）固定在终端位置，防止远端 方向相对于盒保持器（3）。 提供了一种用于药物输送装置（1）的组件，其包括盒（4），调节构件（12,25,28,34）和盒保持器（3）。 药筒保持器（3）具有远端和近端。 调节构件（12,25,28,34）固定在盒保持架（3）上。 调节构件（12,25,28,34）将盒（4）的远端部分相对于盒保持器（3）的远端部分保持一段距离。

    METHOD AND ASSEMBLY FOR A DRUG DELIVERY DEVICE
    46.
    发明申请
    METHOD AND ASSEMBLY FOR A DRUG DELIVERY DEVICE 审中-公开
    用于药物递送装置的方法和组装

    公开(公告)号：US20120283660A1

    公开(公告)日：2012-11-08

    申请号：US13498377

    申请日：2010-09-29

    申请人： Christopher Jones ,  Robert Veasey ,  Garen Kouyoumjian ,  Catherine Anne Macdonald

    发明人： Christopher Jones ,  Robert Veasey ,  Garen Kouyoumjian ,  Catherine Anne Macdonald

    IPC分类号： A61M5/31 ,  A61M5/315

    CPC分类号： A61M5/24 ,  A61M5/3129 ,  A61M5/3146 ,  A61M5/31511 ,  A61M5/31555 ,  A61M5/3158 ,  A61M2005/2407 ,  A61M2005/2488 ,  A61M2005/2492

    摘要： A method for securing a cartridge to a body for a drug delivery device is provided comprising the step of securing the cartridge to the body by means of a releasable connection to prevent accidental relative movement between the cartridge (4) and the body during assembly of the device. Afterwards, the releasable connection is modified irreversably into a non-releasable connection such that the cartridge is permanently secured to the body. Furthermore, an assembly for a drug delivery device is provided comprising a cartridge, a body, a first connection means and a second connection means. The first connection means and the second connection means are configured to mechanically cooperate to form a releasable connection. The releasable connection is suitable for releasably securing the cartridge to the body. The releasable connection prevents accidental relative movement between the cartridge and the body during assembly of the device. The first connection means and the second connection means are irreversably non-releasably secured to each other.

    摘要翻译： 提供了一种用于将药筒固定到用于药物输送装置的主体上的方法，包括通过可释放的连接将药筒固定到身体的步骤，以防止药筒（4）和身体在组装期间的意外相对运动 设备。 之后，可释放的连接被不可逆地修改成不可释放的连接，使得盒被永久地固定到主体上。 此外，提供了用于药物输送装置的组件，其包括药筒，主体，第一连接装置和第二连接装置。 第一连接装置和第二连接装置被配置为机械协作以形成可释放的连接。 可释放的连接适合于将盒可释放地固定到身体。 可释放的连接防止在装置组装期间盒和主体之间的意外的相对移动。 第一连接装置和第二连接装置不可逆地不可释放地彼此固定。

    Assembly and Piston Rod for a Drug Delivery Device
    47.
    发明申请
    Assembly and Piston Rod for a Drug Delivery Device 审中-公开
    装配和活塞杆用于药物输送装置

    公开(公告)号：US20120283652A1

    公开(公告)日：2012-11-08

    申请号：US13395689

    申请日：2010-09-29

    申请人： Catherine Anne MacDonald ,  Robert Veasey ,  Christopher Jones ,  Garen Kouyoumjian

    发明人： Catherine Anne MacDonald ,  Robert Veasey ,  Christopher Jones ,  Garen Kouyoumjian

    IPC分类号： A61M5/315

    CPC分类号： A61M5/3146 ,  A61M5/24 ,  A61M5/31543 ,  A61M5/31555 ,  A61M5/31556 ,  A61M5/3156 ,  A61M5/31575 ,  A61M5/3158 ,  A61M2005/2407 ,  A61M2005/2488 ,  A61M2005/2492

    摘要： A drive mechanism for a drug delivery device (1) comprises a housing (2), a drive member (5) and a piston rod assembly (32). The drive member (5) is configured to be axially displaced in a dose setting direction with respect to the housing (2) for setting a dose of a drug (24) and to be axially displaced in a dose delivery direction with respect to the housing (2) for delivering the set dose of the drug (24). The drive member (5) comprises a drive feature (15).The piston rod assembly (32) comprises a set of interaction surfaces (17) for mechanical interaction with the drive feature (15), with at least two interaction surfaces (17) being axially and angularly offset with respect to each other. When the drive member (5) is displaced in the dose delivery direction for delivering the set dose, the drive feature (15) mechanically interacts with one of the interaction surfaces (17) and the piston rod assembly (32) rotates with respect to the housing (2), thereby rotating and axially displacing another one of the interaction surfaces (17) from a non-interaction position into an interaction position in which the drive feature (15) may interact with the other one of the interaction surfaces (17) when the drive mechanism is actuated once more for setting and delivering a further dose. Also, a piston rod (3) is proposed.

    摘要翻译： 用于药物输送装置（1）的驱动机构包括壳体（2），驱动构件（5）和活塞杆组件（32）。 驱动构件（5）构造成相对于壳体（2）在剂量设定方向上轴向移位，用于设定药物（24）的剂量，并且相对于壳体在剂量递送方向上轴向移位 （2）用于递送药物的设定剂量（24）。 驱动构件（5）包括驱动特征（15）。 活塞杆组件（32）包括用于与驱动特征（15）机械相互作用的一组相互作用表面（17），其中至少两个相互作用表面（17）相对于彼此轴向和角度偏移。 当驱动构件（5）在剂量递送方向上移位以输送设定剂量时，驱动构件（15）与相互作用表面（17）中的一个机械地相互作用，并且活塞杆组件（32）相对于 从而将另一个相互作用表面（17）从非相互作用位置旋转并轴向移位到相互作用位置，在该相互作用位置中，驱动特征（15）可与相互作用表面（17）中的另一个相互作用， 当驱动机构再次被致动以设定和递送另外的剂量时。 另外，提出了活塞杆（3）。