摘要:
The invention is directed to formulations of pharmaceutical compounds, such as the Cyclohexylamines and Aminoadamantanes which have antimicrobial properties. In particular, it is directed to aqueous based formulations with reduced amounts of preservatives which allow safe and convenient administration and flexible dosing and which, in the case of oral formulations, are easy to swallow. Optionally, the compositions contain components that provide the requisite stability and shelf life while reducing or avoiding incrustation of the composition around the container closure which leads to leaks and difficulty in opening the container.
摘要:
The present invention relates to an immediate release solid oral dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable coating, wherein the active ingredient exhibits dose proportionality and is released at a dissolution rate of more than about 80% within about the first 60 minutes following entry of said form into a use environment. The dosage form is direct compressed and has a hardness within the range of between about 3 and about 40 Kp, exhibits an average Tmax within the range of about 2 to about 8 hours with an active ingredient load within the range of about 2.5 to about 150 mg. The formulation allows for dose-proportional compositions for once daily or b.i.d. dosing, while maintaining a steady average range of Tmax.
摘要翻译:本发明涉及含有1-氨基环己烷,优选美金刚或奈拉美生和任选的药学上可接受的包衣的立即释放的固体口服剂型,其中活性成分表现出剂量比例,并以大于约80%的溶解速率释放 大约在所述表格进入使用环境后的前60分钟。 该剂型是直接压制的并且具有在约3至约40Kp范围内的硬度,在约2至约8小时的范围内显示平均T max max,活性成分负载在 约2.5至约150mg的范围。 该制剂允许剂量比例组合物每天一次或b.i.d。 同时保持T max的稳定平均范围。
摘要:
The present invention relates to polyurethane elastomer systems for industrial and paper mill rolls and more particularly to polyurethane covered rolls made from a new polyurethane composition of a polyurethane prepolymer cured with an aromatic diamine and a hydroxyl-terminated polybutadiene resin. Rolls made with this new polyurethane composition exhibit improved dynamics, hydrolytic stability, and reduced water vapor transmission over conventional polyurethane elastomer systems.
摘要:
Some embodiments provide a method for managing a video conference between a first device and a second device. The method identifies a first ceiling bit rate for transmitting video conference data to the second device through the communication channel. The method identifies a current bit rate that is less than the first ceiling bit rate. The method receives networking data regarding the communication channel from the second device. The method determines, from the received network data, that the communication channel will sustain an increase in the current bit rate. The method increments the current bit rate. The method iteratively performs the receiving, determining, and incrementing operations until a determination is made that the communication channel will not sustain the increase in the current bit rate.
摘要:
An improved stabilized biocidal delivery system has been found which increases the efficiency and effectiveness of introducing antimicrobial compounds into complex bio-film matrices through the use of liposome emulsion in an ethoxylated compound, thereby removing the bio-fouling in industrial water bearing systems, including piping, heat exchangers, condensers, filtration systems and fluid storage tanks. The liposome emulsion is comprised of a vesicle encapsulated biocide that is stabilized against chemical and heat degradation over longer periods of time than previously possible through the incorporation of one or more stabilizer compounds.
摘要:
An apparatus, method, and machine-readable medium are described for establishing, maintaining and utilizing backup channels in a peer-to-peer (“P2P”) network. For example, in one embodiment, each mobile device can establish a primary P2P communication channel with one or more other mobile devices. Once the primary channel is established, each mobile device can use the primary channel to exchange secondary channel connection data and can subsequently open one or more secondary P2P communication channels with the other mobile devices. Upon detecting that the primary P2P communication channel has failed or has degraded below a specified threshold (e.g., a bandwidth or bitrate threshold), one of the secondary P2P communication channels can be automatically promoted to a primary P2P communication channel.
摘要:
A method and apparatus for automatically detecting stent struts in an image is disclosed whereby the inner boundary, or lumen, of an artery wall is first detected automatically and intensity profiles along rays in the image are determined. In one embodiment, detection of the lumen boundary may be accomplished, for example, by evolving a geometric shape, such as an ellipse, using a region-based algorithm technique, a geodesic boundary-based algorithm technique or a combination of the two techniques. Once the lumen boundary has been determined, in another embodiment, the stent struts are detected using a ray shooting algorithm whereby a ray is projected outward in the OCT image starting from the position in the image of the OCT sensor. The intensities of the pixels along the ray are used to detect the presence of a stent strut in the image.
摘要:
The present invention discloses a method and an apparatus for eliminating frequency-domain interference signals, and relates to communication technologies. The method includes: multiplying a frequency-domain channel estimation value by a frequency-domain interference signal to obtain a frequency-domain received interference signal; and subtracting the frequency-domain received interference signal from the frequency-domain received signal to obtain the frequency-domain received signal free of interference. The apparatus includes a multiplying module and a subtracting module. A frequency-domain equalizer includes an interference signal obtaining module and an interference signal eliminating module. The technical solution provided herein eliminates interference signals in the frequency domain, and saves the calculation load in contrast with elimination of time-domain interference signals.
摘要:
The present invention provides a digital camera structure structured from a rotating portion and a fixed portion. The rotating portion is configured with a lens used to capture desired images being filmed. Moreover, a magnetic flux device, attracted to a magnetic flux body of the fixed portion, is held within a housing of the rotating portion. The rotating portion and the fixed portion are made to effectively mutually attract by means of a magnetic force. Moreover, disposition of a retaining cavity on the fixed portion is used to enable the rotating portion to permit multidirectional and large-scale adjustment of the filming angle. The rotating portion can be independently joined to a magnetic piece, magnetism of which enables the rotating portion and the magnetic piece to be attracted to a magnetically attracting device, which better benefits the general user in the convenient use of the lens on the rotating portion.
摘要:
The present invention discloses a protein that has strong affinity to thrombopoietin receptor (C-MPL) and the nucleotide sequences of the protein. The protein is capable of increasing the numbers of platelets and enhancing the blood clotting in vivo and is named as platelet promoting protein (PPP). The protein and its nucleotide sequences can be used for the treatment of blood diseases including thrombocytopenia.