公开(公告)号：US20070108704A1

公开(公告)日：2007-05-17

申请号：US11266454

申请日：2005-11-03

申请人： Colin Craig ,  Enzo Dibenedetto ,  Christopher Kmetz ,  Jonathan Miller ,  Mark Sondeen

发明人： Colin Craig ,  Enzo Dibenedetto ,  Christopher Kmetz ,  Jonathan Miller ,  Mark Sondeen

IPC分类号： F16J15/34

CPC分类号： F16J15/3468 ,  F01D11/003 ,  F05D2240/55

摘要： A face seal includes a seal seat 24 and a seal element 52 carried by a seal housing 32. The seal element cooperates with the seal seat to establish a seal. The housing includes a support 44 for the seal element and a shroud 42 for effecting a gradual transition between a normal condition and a deteriorated condition. The shroud 42 may have a tip 74 whose properties differ in lubricity, hardness or abradability relative to other portions of the seal housing.

摘要翻译： 面密封件包括密封座24和由密封壳体32承载的密封元件52.密封元件与密封座配合以建立密封。 壳体包括用于密封元件的支撑件44和用于在正常状态和恶化条件之间逐渐过渡的护罩42。 护罩42可以具有相对于密封壳体的其它部分的润滑性，硬度或耐磨性不同的尖端74。

公开(公告)号：US20070034243A1

公开(公告)日：2007-02-15

申请号：US11171311

申请日：2005-07-01

申请人： Jonathan Miller

发明人： Jonathan Miller

IPC分类号： A61H3/00

CPC分类号： A61H3/04 ,  A61H2003/046 ,  A61H2201/1633

摘要： A walking stabilizer equipped to combat the effects of akinesia paradoxica by employing a novel method and device to regulate and actuate a projection instrument which generates a pattern perpendicular to the user's direction of travel. The regulating and actuating device comprises a two pole series switch circuit configuration in tandem with the walking stabilizer's novel dual action braking mechanism. The projection device is only operable when the user concurrently selects its use and when the walker stabilizer is free for movement or in contact with the patient.

摘要翻译： 一种步行稳定器，用于通过采用新颖的方法和装置来调节和致动投影仪器，以产生垂直于使用者行进方向的图案来防止运动障碍悖论的影响。 调节和致动装置包括与步行稳定器的新型双作用制动机构串联的双极串联开关电路配置。 投影装置仅在用户同时选择其使用以及当步行者稳定器自由移动或与患者接触时才可操作。

公开(公告)号：US20070021926A1

公开(公告)日：2007-01-25

申请号：US11528974

申请日：2006-09-27

申请人： Jonathan Miller ,  Chen Zeng ,  Ned Wingreen ,  Chao Tang

发明人： Jonathan Miller ,  Chen Zeng ,  Ned Wingreen ,  Chao Tang

IPC分类号： G06F19/00

CPC分类号： G16B15/00 ,  G16B30/00

摘要： The present invention provides a method and system for identifying, designing, and synthesizing proteins and protein backbones. The invention permits the qualitative identification of designable protein configurations and synthesis of protein folds. The method and system involve generating backbone protein configurations using a set of dihedral angle pairs, normalizing the total surface exposure of the configurations; generating a random set of sequences of hydrophobicities with uniform weight on the space of allowed sequences; determining, for each randomly generated sequence, which of the remaining configurations is the ground state; recording a ground-state configuration for each sequence wherein the desirable configurations are those containing the most sequences with that configuration as their ground state and finally, synthesizing sequences of amino acids for the desirable configurations.

公开(公告)号：US20060159645A1

公开(公告)日：2006-07-20

申请号：US11238815

申请日：2005-09-29

申请人： Jonathan Miller ,  Meghan Russell ,  Lynn Halas

发明人： Jonathan Miller ,  Meghan Russell ,  Lynn Halas

IPC分类号： A61K8/89

CPC分类号： A61Q19/10 ,  A61K8/25 ,  A61K8/585 ,  A61K8/895 ,  A61K2800/28

摘要： This invention relates to a method of providing lubricious surfaces, more particularly to a method of providing lubricious characteristics to skin surfaces that come into contact with other surfaces so as to prevent or treat chafing and/or irritation.

摘要翻译： 本发明涉及一种提供光滑表面的方法，更具体地说，涉及提供与其它表面接触的皮肤表面的润滑特性以防止或治疗擦伤和/或刺激的方法。

公开(公告)号：US20050250173A1

公开(公告)日：2005-11-10

申请号：US10841569

申请日：2004-05-10

申请人： Charles Davis ,  Richard Cook ,  Rober Matikyan ,  Manish Kochar ,  Jason Harley ,  Jonathan Miller ,  Jeffrey Daniels

发明人： Charles Davis ,  Richard Cook ,  Rober Matikyan ,  Manish Kochar ,  Jason Harley ,  Jonathan Miller ,  Jeffrey Daniels

IPC分类号： B01L9/00 ,  G01N35/02 ,  G01N35/04 ,  C12Q1/02 ,  G01N21/00

CPC分类号： G01N35/028 ,  G01N2035/042

摘要： A detection system may include a moveable tray configured to hold a multi-cell container of one or more reagents and/or one or more samples. A driving mechanism may be configured to reciprocate the tray in the first linear direction to agitate contents of the container, and may be configured to conduct electrochemiluminescence or other measurements on samples located in the container. The system may include an apparatus for retaining a container, a device for detecting the presence of a container, an apparatus for training a probe to locate and aspirate one or more reagents and/or one or more samples, a latching mechanism for moving parts in the system, and/or a positive displacement pump. A controller may be configured to control linear reciprocation of the tray to have one of a piecewise constant velocity profile and piecewise constant acceleration profile in which the number of piecewise constants does not exceed 24.

摘要翻译： 检测系统可以包括配置成容纳一个或多个试剂和/或一个或多个样品的多细胞容器的可移动托盘。 驱动机构可以被配置为使托盘沿第一线性方向往复移动以搅拌容器的内容物，并且可以被配置为对位于容器中的样品进行电化学发光或其它测量。 该系统可以包括用于保持容器的装置，用于检测容器的存在的装置，用于训练探针以定位和吸出一个或多个试剂和/或一个或多个样品的装置，用于将部件移动 系统和/或容积式泵。 控制器可以被配置为控制托盘的线性往复运动以具有分段恒定速度分布和分段恒定加速度分布之一，其中分段常数的数量不超过24。

公开(公告)号：US20050209892A1

公开(公告)日：2005-09-22

申请号：US10708709

申请日：2004-03-19

申请人： Jonathan Miller

发明人： Jonathan Miller

IPC分类号： G06Q10/00 ,  G06F17/60

CPC分类号： G06Q10/00 ,  G06Q40/08

摘要： The present invention relates generally to automatic insurance verification, and more specifically, to a non-invasive method and system for automatically determining, by any person with computer, wireless, or telephone access and in real-time, if an insured object of value is or is not insured irrespective of insurer location, jurisdiction, language, type, time, and also the internal operations, software platform and communications protocols used by insurers and/or governmental entities. It is an insurance verification, not an insurance reporting or tracking system and because it maintains no personal data of any kind, and can modify no record, it can deliver only very limited features regarding reporting or tracking. The present invention can however, provide absolute assurance of current insurance status at all times, provides a unique method of access which resolves all current failures and is non-invasive, providing complete privacy for all parties involved, (the absence of all personal information and the access method used ensures that all access and data is inherently non-invasive). This invention further ensures that any check of status, at insurer or governmental registration, (including “e-registration”, inspection, or any other location and time when and where a jurisdiction or insurer requires such a status check, will result in an instant and totally accurate status response. This system is based upon the assignment of a unique identifier, also known in this present art as a “UC” or “Unique Code” which then provides a method of accurate data, (including status checks), without reliance on “VINs”, (vehicle identification numbers), policy number or other identifiers which are often incorrect. The UC is assigned to any combination of two or more elements that are “gleaned”, (file field extraction and related system and methods), one of which is always current status. The extraction of these selected fields from data streams may be done by a number of prior art techniques, and the three most common have been detailed. First demonstrated to government officials in 1999 as a medical version and later the same year as a vehicle version, it has been demonstrated and documented since to a great many Federal and State governmental entities. This present invention has also been demonstrated to several foreign governments but incorporates no technologies that create any possible security risk for any government, insurer, individual, and especially to the national security of the United States.

公开(公告)号：US20050153369A1

公开(公告)日：2005-07-14

申请号：US11003951

申请日：2004-12-03

申请人： Jonathan Miller ,  Vicki Lyle

发明人： Jonathan Miller ,  Vicki Lyle

IPC分类号： C07K14/00 ,  C07K14/705 ,  C07K16/28 ,  G01N33/53 ,  G01N33/567

CPC分类号： C07K14/705 ,  C07K14/001 ,  C07K14/70596 ,  C07K16/2896 ,  C07K2317/34

摘要： The present invention is directed to an isolated peptide that functionally mimics a binding site for a monoclonal antibody, the monoclonal antibody recognizing an epitope within the human platelet glycoprotein Ib/IX complex. This peptide is called a mimotope. The invention also provides an isolated molecule capable of binding to the peptide, or the mimotope, which molecule can be an antibody, a second peptide, a carbohydrate, a DNA molecule, an RNA molecule, or other naturally or chemically synthesized molecules. This isolated molecule is called an anti-mimotope. Mimotopes mimicking the binding site for monoclonal antibody C-34 and SZ-2, as well as anti-mimotopes to the C-34 mimotopes, are specifically provided.

摘要翻译： 本发明涉及功能上模拟单克隆抗体的结合位点的分离的肽，该单克隆抗体识别人血小板糖蛋白Ib / IX复合物内的表位。 该肽被称为模拟表位。 本发明还提供能够结合肽或模拟表位的分离的分子，该分子可以是抗体，第二肽，碳水化合物，DNA分子，RNA分子或其它天然或化学合成的分子。 这种分离的分子称为抗模拟表位。 具体提供了模拟单克隆抗体C-34和SZ-2的结合位点的模拟表位，以及C-34模拟表位的抗模拟表位。

公开(公告)号：US4577366A

公开(公告)日：1986-03-25

申请号：US620149

申请日：1984-06-13

申请人： Jonathan Miller ,  Robert C. Berfield ,  Robert L. Crevling, Jr.

发明人： Jonathan Miller ,  Robert C. Berfield ,  Robert L. Crevling, Jr.

IPC分类号： A47L9/04

CPC分类号： A47L9/0422 ,  A47L9/045

摘要： A nozzle assembly for a vacuum cleaner is provided with floor engaging wheels that are frictionally engaged with and rotate additional wheels that are secured to the ends of a brush in a manner such that rotation of the additional wheels causes the brush to rotate. As the vacuum nozzle assembly is moved back and forth across a floor that requires cleaning, the wheels engaging the floor are caused to rotate thereby rotating the brush in the opposite direction. The latter agitates the carpet or other floor covering to loosen and direct dirt particles toward the inlet slot of the vacuum cleaner nozzle.

摘要翻译： 用于真空吸尘器的喷嘴组件设置有地板接合轮，所述地板接合轮摩擦地接合并旋转附加的轮，所述另外的轮以固定到刷的端部的方式使得附加轮的旋转使得刷旋转。 当真空喷嘴组件在需要清洁的地板上来回移动时，使与地板接合的轮子转动，从而沿相反方向旋转刷子。 后者搅拌地毯或其他地板覆盖物以松动并将污垢颗粒引导到真空吸尘器喷嘴的入口槽。

公开(公告)号：US4538971A

公开(公告)日：1985-09-03

申请号：US514491

申请日：1983-07-18

申请人： Jonathan Miller ,  Rudolph W. Wacek ,  Robert C. Berfield ,  Ronald F. Meland ,  Robert L. Crevling, Jr. ,  Lonnie B. Lawson, Jr.

发明人： Jonathan Miller ,  Rudolph W. Wacek ,  Robert C. Berfield ,  Ronald F. Meland ,  Robert L. Crevling, Jr. ,  Lonnie B. Lawson, Jr.

IPC分类号： A47L9/00 ,  A47L7/00 ,  A47L9/22 ,  F04B17/00 ,  F04B35/04

CPC分类号： A47L7/0028 ,  A47L7/0042 ,  Y10S55/03

摘要： A by-pass type wet/dry vacuum is provided with a removable lid assembly that includes an electric motor having a lower insulating housing, a cover for the upper end of the motor, a blower housing including vanes for regulating flow of main blower air, a fan having a pancake type impeller, a fan cover and a tank lid having an integrally formed float cage. Assembly of these elements is achieved by making all electrical connections between the motor, a power cord extending to the motor cover, and a manually operated control switch mounted on the motor cover; inverting the motor cover, inserting the upper end of the motor downward into the cover where the former is grasped by snap type retainers formed integrally with the cover, inverting the blower housing and securing same to the motor cover with a plurality of screws, securing the impeller to the lower end of the motor shaft, inverting the fan cover and securing it to the blower housing utilizing screws, placing the float ball in a depression of the fan cover, inverting the tank lid and securing same to the blower housing by means of screws. All of the above elements are assembled to one another without the necessity of lifting any of the elements once they are secured to the other elements.

摘要翻译： 旁路式湿/干真空装置设置有可拆卸盖组件，其包括具有下绝缘壳体的电动机，用于电动机上端的盖，鼓风机壳体，其包括用于调节主鼓风机空气流量的叶片， 具有扁平型叶轮的风扇，风扇罩和具有整体形成的浮子笼的箱盖。 这些元件的组装通过使电动机，延伸到电动机罩的电源线和安装在电动机盖上的手动操作的控制开关之间的所有电气连接实现; 翻转电机盖，将电机的上端向下插入盖中，在该盖中，前者由与盖一体形成的卡扣式保持器夹紧，使用多个螺钉将鼓风机​​壳体翻转并固定到马达盖上， 叶轮到电机轴的下端，将风扇盖翻转并用螺丝将其固定到鼓风机壳体上，将浮球放置在风扇罩的凹陷处，将油箱盖翻转并将其固定到鼓风机壳体上，借助于 螺丝 所有上述元件被组装成彼此，而不需要在将其固定到其它元件上之后提起任何元件。

公开(公告)号：US4213224A

公开(公告)日：1980-07-22

申请号：US935265

申请日：1978-08-21

申请人： Jonathan Miller

发明人： Jonathan Miller

IPC分类号： A47L9/00 ,  A47L5/24

CPC分类号： A47L5/24

摘要： A portable vacuum cleaner with a bypass fan arrangement: the main fan draws air into the vacuum cleaner housing axially and discharges it radially from the housing; a plenum chamber receives the air from the housing outlet and redirects the outlet air in a direction away from the housing inlet; the motor for the main fan is cooled by a motor cooling fan drawing air over the motor from the end of the motor housing opposite its inlet end; the main air flow and cooling air flows being separate; the housing is shaped internally to assure the separation of air flows just described.

摘要翻译： 具有旁路风扇装置的便携式真空吸尘器：主风扇轴向将空气吸入真空吸尘器壳体并从壳体径向放电; 充气室从壳体出口接收空气并且使排出空气沿远离壳体入口的方向重新定向; 用于主风扇的电动机由电动机冷却风扇冷却，电动机从电动机壳体的与其入口端相对的端部抽出空气; 主要的空气流和冷却空气流分开; 外壳在内部成形，以确保刚刚描述的气流的分离。