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    CYTOKINE RECEPTOR ZALPHA11
    41.
    发明申请
    CYTOKINE RECEPTOR ZALPHA11 审中-公开
    细胞因子受体ZALPHA11

    公开(公告)号：US20070172917A1

    公开(公告)日：2007-07-26

    申请号：US11537879

    申请日：2006-10-02

    申请人： Scott Presnell ,  Darrell Conklin ,  Julia Novak ,  Angela Hammond

    发明人： Scott Presnell ,  Darrell Conklin ,  Julia Novak ,  Angela Hammond

    IPC分类号： C12P21/06 ,  C07H21/04 ,  C07K14/705

    CPC分类号： C07H21/04 ,  C07K14/715 ,  C07K16/1232 ,  C07K16/2866 ,  C07K2317/32 ,  C07K2319/00

    摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zalpha11, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zalpha11, are located on chromosome 16, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

    摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zalpha11，一种新的细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zalpha11的多核苷酸位于染色体16上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。

    ANTIBODIES TO CYTOKINE RECEPTOR ZALPHA11
    42.
    发明申请
    ANTIBODIES TO CYTOKINE RECEPTOR ZALPHA11 有权
    细胞因子受体ZALPHA11抗体

    公开(公告)号：US20070178096A1

    公开(公告)日：2007-08-02

    申请号：US11537835

    申请日：2006-10-02

    申请人： Scott Presnell ,  Darrell Conklin ,  Julia Novak ,  Angela Hammond

    发明人： Scott Presnell ,  Darrell Conklin ,  Julia Novak ,  Angela Hammond

    IPC分类号： A61K39/395 ,  C12P21/08 ,  C07K16/28

    CPC分类号： C07H21/04 ,  C07K14/715 ,  C07K16/1232 ,  C07K16/2866 ,  C07K2317/32 ,  C07K2319/00

    摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zalpha11, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zalpha11, are located on chromosome 16, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

    摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zalpha11，一种新的细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zalpha11的多核苷酸位于染色体16上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。

    METHODS OF DETECTING CYTOKINE RECEPTOR ZCYTOR19 LIGAND
    43.
    发明申请
    METHODS OF DETECTING CYTOKINE RECEPTOR ZCYTOR19 LIGAND 审中-公开
    检测细胞因子受体ZCYTOR19配体的方法

    公开(公告)号：US20070048804A1

    公开(公告)日：2007-03-01

    申请号：US11539283

    申请日：2006-10-06

    申请人： Scott Presnell ,  Wenfeng Xu ,  Julia Novak ,  Theodore Whitmore ,  Francis Grant

    发明人： Scott Presnell ,  Wenfeng Xu ,  Julia Novak ,  Theodore Whitmore ,  Francis Grant

    IPC分类号： G01N33/567 ,  G01N33/53

    CPC分类号： C07K14/47 ,  C07K14/715 ,  C07K2319/00 ,  Y10T436/143333

    摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor19, a novel class II cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor19, are located on chromosome 1p36.11, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

    摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zcytor19，一种新型的II类细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zcytor19的多核苷酸位于染色体1p36.11上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。

    CYTOKINE RECEPTOR ZALPHA11
    44.
    发明申请
    CYTOKINE RECEPTOR ZALPHA11 审中-公开

    公开(公告)号：US20070111941A1

    公开(公告)日：2007-05-17

    申请号：US11537874

    申请日：2006-10-02

    申请人： Scott Presnell ,  Darrell Conklin ,  Julia Novak ,  Angela Hammond

    发明人： Scott Presnell ,  Darrell Conklin ,  Julia Novak ,  Angela Hammond

    IPC分类号： A61K38/17 ,  C07K14/715 ,  C07H21/04 ,  C12P21/06

    CPC分类号： C07K14/715

    摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zalpha11, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zalpha11, are located on chromosome 16, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

    METHODS OF DETECTING CANCER WITH ANTIBODIES TO CYTOKINE RECEPTOR ZCYTOR19
    46.
    发明申请
    METHODS OF DETECTING CANCER WITH ANTIBODIES TO CYTOKINE RECEPTOR ZCYTOR19 有权
    检测癌症与细胞因子受体ZCYTOR19抗体的方法

    公开(公告)号：US20070117165A1

    公开(公告)日：2007-05-24

    申请号：US11539286

    申请日：2006-10-06

    申请人： Scott Presnell ,  Wenfeng Xu ,  Julia Novak ,  Theodore Whitmore ,  Francis Grant

    发明人： Scott Presnell ,  Wenfeng Xu ,  Julia Novak ,  Theodore Whitmore ,  Francis Grant

    IPC分类号： G01N33/574

    CPC分类号： C07K14/47 ,  C07K14/715 ,  C07K2319/00 ,  Y10T436/143333

    摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor19, a novel class II cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor19, are located on chromosome 1p36.11, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

    摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zcytor19，一种新型的II类细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zcytor19的多核苷酸位于染色体1p36.11上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。