公开(公告)号：US10980451B2

公开(公告)日：2021-04-20

申请号：US17027418

申请日：2020-09-21

Applicant: DexCom, Inc.

Inventor： Jeffrey R. Wedekind ,  Douglas William Burnette ,  Aditya Mandapaka ,  Zebediah L. McDaniel ,  Peter C. Simpson ,  Arturo Garcia

IPC: A61B5/00 ,  A61B5/145 ,  H04L29/06 ,  A61B5/1486 ,  G16H40/60 ,  G16H10/60 ,  A61B5/11 ,  G16H40/63 ,  G16H40/67 ,  G16H10/40 ,  H04L29/08

Abstract: Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.

公开(公告)号：US20210076989A1

公开(公告)日：2021-03-18

申请号：US16951596

申请日：2020-11-18

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US10932700B2

公开(公告)日：2021-03-02

申请号：US16924101

申请日：2020-07-08

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker ,  Mark C. Brister ,  Paul V. Goode, Jr. ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Jack Pryor ,  Matthew D. Wightlin

IPC: A61B5/1495 ,  A61B5/1486 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/05 ,  A61B5/00 ,  A61B5/15 ,  A61B17/34 ,  A61M5/172 ,  A61M5/158 ,  A61M5/142

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20210022653A1

公开(公告)日：2021-01-28

申请号：US17035478

申请日：2020-09-28

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Robert J. Boock ,  Monica A. Rixman ,  Peter C. Simpson ,  Mark C. Brister ,  Mark C. Shults

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  C12Q1/00 ,  G01N33/543 ,  G01N33/66

Abstract: Biointerface membranes are provided which can be utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device incorporating such membranes are provided.

公开(公告)号：US10799159B2

公开(公告)日：2020-10-13

申请号：US16790401

申请日：2020-02-13

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Steve Masterson ,  John Nolting ,  James R. Petisce ,  Jack Pryor ,  Sean Saint ,  Peter C. Simpson ,  Vance Swanson ,  Matthew D. Wightlin

IPC: A61B5/145 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/00 ,  A61B5/1473 ,  A61B17/34 ,  A61B5/05 ,  A61B5/15 ,  A61M5/158 ,  A61M5/172 ,  A61M5/142

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US10799158B2

公开(公告)日：2020-10-13

申请号：US16691438

申请日：2019-11-21

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Steve Masterson ,  John Nolting ,  James R. Petisce ,  Jack Pryor ,  Sean Saint ,  Peter C. Simpson ,  Vance Swanson ,  Matthew D. Wightlin

IPC: A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/00 ,  A61B5/15 ,  A61B5/05 ,  A61B17/34 ,  A61M5/172 ,  A61M5/158 ,  A61M5/142

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20200289038A1

公开(公告)日：2020-09-17

申请号：US16889646

申请日：2020-06-01

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1486 ,  C12Q1/00

Abstract: Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.

公开(公告)号：US10737025B2

公开(公告)日：2020-08-11

申请号：US15684361

申请日：2017-08-23

Applicant: DexCom, Inc.

Inventor： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea J. Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC: A61M5/172 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G06F19/00 ,  G08B21/04 ,  H04M1/725 ,  G06N5/04 ,  G16H20/17 ,  G16H40/67 ,  G16H40/63

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US10722162B2

公开(公告)日：2020-07-28

申请号：US16586407

申请日：2019-09-27

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: G08B21/20 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US10709363B2

公开(公告)日：2020-07-14

申请号：US16691422

申请日：2019-11-21

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Steve Masterson ,  John Nolting ,  James R. Petisce ,  Jack Pryor ,  Sean Saint ,  Peter C. Simpson ,  Vance Swanson ,  Matthew D. Wightlin

IPC: A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/00 ,  A61B17/34 ,  A61B5/05 ,  A61B5/15 ,  A61M5/158 ,  A61M5/172 ,  A61M5/142

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.