公开(公告)号：US11559230B2

公开(公告)日：2023-01-24

申请号：US16254210

申请日：2019-01-22

申请人： DexCom, Inc.

发明人： Anna Claire Harley-Trochimczyk ,  Sebastian Böhm ,  Rui Ma ,  Disha B. Sheth ,  Minglian Shi ,  Kamuran Turksoy

IPC分类号： A61B5/1495 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/01 ,  G16H50/20 ,  G01N27/327 ,  A61B5/024 ,  A61B5/11

摘要： This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.

公开(公告)号：US20210251526A1

公开(公告)日：2021-08-19

申请号：US17207461

申请日：2021-03-19

申请人： DexCom, Inc.

发明人： Michael J. Estes ,  Stephen J. Vanslyke ,  Apurv Ullas Kamath ,  Thomas A. Peyser ,  Lucas Bohnett ,  Aarthi Mahalingam ,  Arturo Garcia ,  Peter C. Simpson ,  Anna Leigh Davis ,  Sebastian Böhm

IPC分类号： A61B5/1495 ,  A61B5/145 ,  G01D3/02 ,  A61B5/00

摘要： Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously.

公开(公告)号：US20200037938A1

公开(公告)日：2020-02-06

申请号：US16596579

申请日：2019-10-08

申请人： DexCom, Inc.

发明人： Daiting Rong ,  Sebastian Böhm ,  Matthew D. Wightlin

IPC分类号： A61B5/145 ,  A61B5/1486

摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes an electrochemical sensor incorporating a silver/silver chloride reference electrode, wherein a capacity of the reference electrode is controlled.

公开(公告)号：US20190320948A1

公开(公告)日：2019-10-24

申请号：US16460906

申请日：2019-07-02

申请人： DexCom, Inc.

发明人： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： A61B5/1495 ,  G01N33/49 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  G01N27/02 ,  G01N27/327 ,  G01D18/00

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20190261903A1

公开(公告)日：2019-08-29

申请号：US16405931

申请日：2019-05-07

申请人： DexCom, Inc.

发明人： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： A61B5/1495 ,  G01N33/49 ,  A61B5/145 ,  G01D18/00 ,  G01N27/327 ,  G01N27/02 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1473

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20190167163A1

公开(公告)日：2019-06-06

申请号：US16250992

申请日：2019-01-17

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Robert J. Boock ,  Paul V. Neale ,  Sebastian Böhm ,  Matthew Wightlin ,  Jack Pryor ,  Jason Mitchell ,  Jeff Jackson ,  Kaushik Patel ,  Antonio C. Llevares

IPC分类号： A61B5/1473 ,  A61B5/145 ,  A61B5/1486 ,  B05C3/10

摘要： Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

公开(公告)号：US20180279928A1

公开(公告)日：2018-10-04

申请号：US15994905

申请日：2018-05-31

申请人： DexCom, Inc.

发明人： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： A61B5/1495 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N27/327 ,  G01N33/49 ,  A61B5/1473

CPC分类号： A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49 ,  H05K999/00 ,  H05K999/99

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20170273606A1

公开(公告)日：2017-09-28

申请号：US15621301

申请日：2017-06-13

申请人： DexCom, Inc.

发明人： Michael J. Estes ,  Stephen J. Vanslyke ,  Apurv Ullas Kamath ,  Thomas A. Peyser ,  Lucas Bohnett ,  Aarthi Mahalingam ,  Arturo Garcia ,  Peter C. Simpson ,  Anna Leigh Davis ,  Sebastian Böhm

IPC分类号： A61B5/1495 ,  G01D3/02 ,  A61B5/145 ,  A61B5/00

CPC分类号： A61B5/1495 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/7203 ,  A61B2560/0223 ,  A61B2562/02 ,  G01D3/022 ,  G06F19/3468

摘要： Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously.

公开(公告)号：US20160324450A1

公开(公告)日：2016-11-10

申请号：US15213259

申请日：2016-07-18

申请人： DexCom, Inc.

发明人： Michael J. Estes ,  Stephen J. Vanslyke ,  Apurv Ullas Kamath ,  Thomas A. Peyser ,  Lucas Bohnett ,  Aarthi Mahalingam ,  Arturo Garcia ,  Peter C. Simpson ,  Anna Leigh Rack-Gomer ,  Sebastian Böhm

IPC分类号： A61B5/1495 ,  A61B5/145 ,  A61B5/00

摘要： Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously.

公开(公告)号：US20160198986A1

公开(公告)日：2016-07-14

申请号：US14956170

申请日：2015-12-01

申请人： DexCom, Inc.

发明人： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： A61B5/1495 ,  A61B5/145 ,  A61B5/00

CPC分类号： A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49 ,  H05K999/00 ,  H05K999/99

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.