公开(公告)号：US10583007B2

公开(公告)日：2020-03-10

申请号：US15366959

申请日：2016-12-01

Applicant: Edwards Lifesciences Corporation

Inventor： Arvin T. Chang ,  Yair A. Neumann ,  Gil Senesh ,  Hernan Altman ,  Scott Louis Pool ,  Hannah Gibson ,  Amanda K. Anderson ,  Peter Phong Tran ,  Ly Th Phan

IPC: A61F2/24

Abstract: A delivery apparatus for a prosthetic implant can include an elongate first shaft, a first suture guide coupled to the first shaft, an elongate second shaft, and a second suture guide coupled to the second shaft. The first shaft can extend coaxially through the second shaft and the second suture guide, the first suture guide can be disposed distal to the second suture guide, and the first suture guide and the second suture guide can be configured to be axially movable relative to each other.

公开(公告)号：US20170156859A1

公开(公告)日：2017-06-08

申请号：US15366959

申请日：2016-12-01

Applicant: Edwards Lifesciences Corporation

Inventor： Arvin T. Chang ,  Yair A. Neumann ,  Gil Senesh ,  Hernan Altman ,  Scott Louis Pool ,  Hannah Gibson ,  Amanda K. Anderson ,  Peter Phong Tran ,  Ly Th Phan

IPC: A61F2/24

CPC classification number: A61F2/2439 ,  A61F2/2418 ,  A61F2/2436

Abstract: A delivery apparatus for a prosthetic implant can include an elongate first shaft, a first suture guide coupled to the first shaft, an elongate second shaft, and a second suture guide coupled to the second shaft. The first shaft can extend coaxially through the second shaft and the second suture guide, the first suture guide can be disposed distal to the second suture guide, and the first suture guide and the second suture guide can be configured to be axially movable relative to each other.

公开(公告)号：US20250049568A1

公开(公告)日：2025-02-13

申请号：US18929335

申请日：2024-10-28

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Hanoch Cohen-Tzemach ,  Tamir S. Levi ,  Yair A. Neumann ,  Tomer Saar ,  Gregory Rinberg

IPC: A61F2/24

Abstract: A radially expandable prosthetic valve can include an annular frame, at least one expansion mechanism, and a biasing member. The annular frame can be radially collapsible and expandable between a radially compressed configuration and a radially expanded configuration. The at least one expansion mechanism can include a first member attached to the frame at a first location and a second member attached to the frame at a second location axially spaced from the first location. Movement of the first member relative to the second member in a first direction can cause the frame to radially expand, and movement of the first member relative to the second member in a second direction, opposite the first direction, causes the frame to radially compress. The biasing member can exert a biasing force against the first member in the first direction, to cause the first member to move relative to the second member, which can further expand the frame as the native annulus enlarges over time.

公开(公告)号：US12201522B2

公开(公告)日：2025-01-21

申请号：US18207822

申请日：2023-06-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Alexander Barash ,  Yair A. Neumann ,  Tomer Saar ,  Ziv Yohanan ,  Noam Nir

IPC: A61F2/24 ,  A61F2/844 ,  A61F2/95

Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.

公开(公告)号：US20240415645A1

公开(公告)日：2024-12-19

申请号：US18817003

申请日：2024-08-27

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Alexander Barash ,  Yair A. Neumann ,  Tomer Saar ,  Ziv Yohanan ,  Noam Nir

IPC: A61F2/24 ,  A61F2/844 ,  A61F2/95

Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.

公开(公告)号：US20230293295A1

公开(公告)日：2023-09-21

申请号：US18134445

申请日：2023-04-13

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Yair A. Neumann ,  Amir Davidesko ,  Kristen Hicks ,  Roy Shitrit

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61M2025/0024

Abstract: An introducer sheath can be used to safely introduce a delivery apparatus into a patient’s vasculature (e.g., via the femoral artery). It is advantageous to visualize the placement of an introducer sheath within the vasculature using an imaging system. The sheaths disclosed herein include radiopaque features that assist with imaging without sacrificing the low profile, expandability, and other advantageous aspects of the introducer sheath.

公开(公告)号：US20230270545A1

公开(公告)日：2023-08-31

申请号：US18144049

申请日：2023-05-05

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Oren Cohen ,  Ofir Witzman ,  Yair A. Neumann

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2439 ,  A61F2/2418 ,  A61F2002/9511

Abstract: A prosthetic valve delivery apparatus can comprise a handle, an outer shaft extending distally from the handle, a gear mechanism arranged distal to the outer shaft, an input torque shaft extending distally from the handle through the outer shaft and having a distal end portion operatively connected to the gear mechanism, and a plurality of output torque shafts operatively connected to and extending distally from the gear mechanism. The gear mechanism is configured to transfer rotational motion from the input torque shaft to the plurality of output torque shafts.

公开(公告)号：US11717400B2

公开(公告)日：2023-08-08

申请号：US17114251

申请日：2020-12-07

Applicant: Edwards Lifesciences Corporation

Inventor： Alexander Barash ,  Yair A. Neumann ,  Tomer Saar ,  Ziv Yohanan ,  Noam Nir

IPC: A61F2/24 ,  A61F2/95 ,  A61F2/844

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2/2439 ,  A61F2/2436 ,  A61F2/844 ,  A61F2/9517 ,  A61F2002/9511

Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.

公开(公告)号：US11446141B2

公开(公告)日：2022-09-20

申请号：US16788090

申请日：2020-02-11

Applicant: Edwards Lifesciences Corporation

Inventor： Anatoly Dvorsky ,  Tamir S. Levi ,  Yair A. Neumann ,  Noa Axelrod Manela ,  Eitan Atias ,  Oren Cohen ,  Elazar Levi Schwarcz ,  Ofir Witzman ,  Noam Miller ,  Boaz Manash ,  Danny M. Garmahi

IPC: A61F2/24 ,  A61F2/95

Abstract: An implantable prosthetic device can include a frame that is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The frame can have a first set of a plurality of struts extending in a first direction, and a second set of a plurality of struts extending in a second direction, and each strut of the first set of struts can be pivotably connected to at least one strut of the second set of struts. Each strut can be curved helically with respect to a first, longitudinal axis of the frame, and each strut can be curved with respect to a second axis that is perpendicular to the first, longitudinal axis of the frame.

公开(公告)号：US20220280287A1

公开(公告)日：2022-09-08

申请号：US17824411

申请日：2022-05-25

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

Abstract: An assembly can comprise a prosthetic valve comprising a radially expandable and compressible frame and a rotatable screw connected to the frame, where the screw comprises a screw head having an annular bore with internal threads, and where the screw is rotatable to radially expand the frame. The assembly further comprises a delivery apparatus releasably coupled to the screw, the delivery apparatus comprising a first shaft and a first head disposed at an end of the first shaft, the first head comprising external threads configured to engage with the internal threads of the screw head, and a second shaft that is coaxial with and surrounds the first shaft, the second shaft comprising a second head disposed at an end of the second shaft. The second head is configured to releasably engage with an exterior surface of the screw head and rotate the screw.