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公开(公告)号：US20230131548A1
公开(公告)日：2023-04-27
申请号：US17913211
申请日：2021-01-14
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Akira TASHIRO , Masahiro KOTANI , Takayuki OHMURA
Abstract: A sample support includes: a substrate having a plurality of through-holes opening on a first surface and on a second surface; a first member having a plurality of first openings and disposed on the first surface; a second member having a plurality of second openings and disposed on the second surface, and; a bonding member disposed between the first member and the second member; and a conductive layer integrally provided on a region of the second surface corresponding to each of the plurality of second openings. The plurality of through-holes include a plurality of first through-holes located between each of the plurality of first openings and each of the plurality of second openings, and a plurality of second through-holes located between the first member and the second member. Each of the plurality of second openings communicate with each of the plurality of first openings through the plurality of first through-holes.
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公开(公告)号：US20230095349A1
公开(公告)日：2023-03-30
申请号：US17795964
申请日：2020-12-01
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Akira TASHIRO , Masahiro KOTANI , Takayuki OHMURA
IPC: H01J49/04
Abstract: A sample support body includes: an insulating substrate having a measurement region formed with a plurality of through holes; a frame formed with an opening part opening to a first face and a second face to correspond to the measurement region, and formed on the first surface such that the opening part overlaps the measurement region when viewed from a thickness direction of the substrate; an adhesive layer to bond the substrate and the frame and having a protruding portion protruding from an inner surface of the opening part toward the measurement region; and a conductive layer having a first portion provided along the inner surface of the opening part, a second portion provided along the first surface of the measurement region, and a third portion provided along a surface of the protruding portion so as to connect the first portion and the second portion.
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公开(公告)号：US20220157587A1
公开(公告)日：2022-05-19
申请号：US17439029
申请日：2019-12-11
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Masahiro KOTANI , Takayuki OHMURA , Akira TASHIRO
Abstract: The sample support is used for ionization of a sample contained in a sample solution dropped using a pipette tip. The sample support includes a substrate formed with a plurality of through holes opened in a first surface and a second surface, and a frame that is formed with a through hole penetrating in a thickness direction of the substrate so as to overlap a measurement region when viewed from the thickness direction and that is bonded to the first surface of the substrate. The through hole of the frame includes a narrow portion having a width smaller than the outer diameter of a tip of the pipette tip.
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公开(公告)号：US20220102126A1
公开(公告)日：2022-03-31
申请号：US17549113
申请日：2021-12-13
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Masahiro KOTANI , Takayuki OHMURA , Takamasa IKEDA
IPC: H01J49/04
Abstract: A sample support body is a sample support body for ionizing a sample, including: a substrate having an irregular porous structure formed to communicate a first surface and a second surface opposite to each other; and a conductive layer provided at least on the first surface.
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公开(公告)号：US20210319991A1
公开(公告)日：2021-10-14
申请号：US17259580
申请日：2019-07-25
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Miu TAKIMOTO , Takayuki OHMURA , Masahiro KOTANI
Abstract: A sample support is a sample support for sample ionization, including: a substrate formed with a plurality of through holes opening to a first surface and a second surface on a side opposite to the first surface; a conductive layer provided not to block the through hole in the first surface; and a frame body provided in a peripheral portion of the substrate to surround an ionization region in which a sample is ionized when viewed in a thickness direction of the substrate, in which a marker for recognizing a position in the ionization region is provided in the frame body.
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Patent Agency Ranking
公开(公告)号：US20210257201A1
公开(公告)日：2021-08-19
申请号：US17262596
申请日：2019-06-19
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Miu TAKIMOTO , Takayuki OHMURA , Masahiro KOTANI
Abstract: A sample support is a sample support for sample ionization, including: a substrate formed with a plurality of through holes opening to a first surface and a second surface on a side opposite to the first surface; a conductive layer provided not to block the through hole in the first surface; and a reinforcement member disposed inside a part of the plurality of through holes.
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公开(公告)号：US20210043437A1
公开(公告)日：2021-02-11
申请号：US16966758
申请日：2019-01-16
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Masahiro KOTANI , Takayuki OHMURA
Abstract: Provided is a sample support body for ionization of a sample. The sample support body includes a substrate including a first surface and a second surface on sides opposite to each other, a first conductive layer provided on the first surface, and a second conductive layer provided on the second surface. A plurality of through-holes opening on the first surface and the second surface are formed in a predetermined region of the substrate, the predetermined region being for ionizing components of the sample. A width of a first opening on the first surface side is larger than a width of a second opening on the second surface side in each of the plurality of through-holes.
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公开(公告)号：US20210033564A1
公开(公告)日：2021-02-04
申请号：US16967046
申请日：2019-01-08
Applicant: Hamamatsu Photonics K.K.
Inventor： Yasuhide NAITO , Takayuki OHMURA , Masahiro KOTANI
IPC: G01N27/62
Abstract: A sample support body includes: a substrate having a first surface and a second surface opposite to each other; and a conductive layer provided on at least the first surface. A plurality of through-holes, which open to the second surface and to a third surface of the conductive layer which is locate at a side opposite to the substrate, are provided in the substrate and the conductive layer. A protective film having a higher affinity with water than the substrate is provided on the second surface, the third surface, and each inner surface of the plurality of through-holes.
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公开(公告)号：US20210027999A1
公开(公告)日：2021-01-28
申请号：US16966131
申请日：2018-11-30
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Masahiro KOTANI , Takayuki OHMURA
Abstract: A sample support body is a sample support body for ionizing a sample, including: a substrate formed with a plurality of first through holes opening to a first surface and a second surface opposite to each other; and a conductive layer provided at least on a peripheral portion of the first through hole in the first surface, in which in a partition portion provided between the adjacent first through holes, a plurality of second through holes communicating the adjacent first through holes are formed.
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50.发明申请公开(公告)号：US20200279729A1
公开(公告)日：2020-09-03
申请号：US16762517
申请日：2018-10-05
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Yasuhide NAITO , Takayuki OHMURA , Masahiro KOTANI
Abstract: A laser desorption/ionization method, includes: a first step of preparing a sample support body including a substrate on which a plurality of through holes opening to a first surface and a second surface facing each other are formed, a conductive layer provided on at least the first surface, and a solvent provided in the plurality of through holes with refractoriness in a vacuum; a second step of mounting a sample on a mounting surface of a mounting portion, and of disposing the sample support body on the sample such that the second surface is in contact with the sample; and a third step of ionizing a component of the sample that is mixed with the solvent and is moved to the first surface side from the second surface side through the through hole by irradiating the first surface with laser beam while applying a voltage to the conductive layer.
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