摘要:
A system and method for secure distribution of a video card public key. The method provides for loading an authentication code module into a processor, authenticating the authentication code module, and executing the authentication code module. Executing the authentication module causes the authentication code module to assert a hardware indicator to access at least one address in a special protected page on a chipset. Receipt of the hardware indicator by the chipset causes a specific reference to be sent via a dedicated port to a circuit card to retrieve a public key from the circuit card.
摘要:
Secure storage and retrieval of a unique value associated with a device to/from a memory of a processing system. In at least one embodiment, the device needs to be able to access the unique value across processing system resets, and the device does not have sufficient non-volatile storage to store the unique value itself. Instead, the unique value is stored in the processing system memory in such a way that the stored unique value does not create a unique identifier for the processing system or the device. A pseudo-randomly or randomly generated initialization vector may be used to vary an encrypted data structure used to store the unique value in the memory.
摘要:
Delivering a Direct Proof private key to a device installed in a client computer system in the field may be accomplished in a secure manner without requiring significant non-volatile storage in the device. A unique pseudo-random value is generated and stored in the device at manufacturing time. The pseudo-random value is used to generate a symmetric key for encrypting a data structure holding a Direct Proof private key and a private key digest associated with the device. The resulting encrypted data structure is stored on a protected on-liner server accessible by the client computer system. When the device is initialized on the client computer system, the system checks if a localized encrypted data structure is present in the system. If not, the system obtains the associated encrypted data structure from the protected on-line server using a secure protocol. The device decrypts the encrypted data structure using a symmetric key regenerated from its stored pseudo-random value to obtain the Direct Proof private key. If the private key is valid, it may be used for subsequent authentication processing by the device in the client computer system.
摘要:
Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
摘要:
The present invention relates to bicyclic compounds according to formula I, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of androgen receptor-associated conditions, such as age-related diseases, for example sarcopenia, wherein R1, R2, R5, X, Y and n are defined herein.
摘要翻译:本发明涉及式I的双环化合物,含有这些化合物的药物组合物和使用这些化合物治疗雄激素受体相关病症例如年龄相关疾病,例如肌肉减少症的方法,其中R 1 R 2,R 5,X,Y和n在本文中定义。
摘要:
Compounds are provided which are useful in the treatment of androgen receptor-associated conditions, such as age-related diseases, which compounds have the structure wherein R1 is hydrogen (H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, arylalkyl or substituted arylalkyl, CO2R4a, CONR4aR4b, and CH2OR4a; R2 is hydrogen (H), OR3, SR3, halo, NHR3, NHCOR4c1, NHCO2R4c1, NHCONR4cR4d and NHSO2R4c; R3 in each functional group is hydrogen (H), alkyl or substituted alkyl, CHF2, CF3 and CON4e; R4, R4a, R4b, R4c, R4c1, R4d, R4e, R4f, R4g, or R4h in each functional group are the same or different and are hydrogen(H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl; R5 and R5′ are the same or different and are hydrogen(H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl, wherein at least one of R5 and R5′ is hydrogen, or R5 and R5′ taken together form a double bond with oxygen (O), sulfur (S), NR7 or CR7R7′; where R7 and R7′ are as defined herein; G is an aryl, heterocyclo or heteroaryl group, wherein said group is mono- or polycyclic, and which is optionally substituted; and n is an integer of 1 or 2, m is an integer of 1 or 2, Z is oxygen (—O—) or NR4h, a prodrug ester, all stereoisomers thereof and a pharmaceutically acceptable salt. A method for treating androgen receptor-associated conditions such as age-related diseases is also provided.
摘要:
Managing authorization tokens within a computer system may be accomplished by creating a master owner token indicating full ownership of a resource within the computer system by a management environment, creating at least one delegate owner token for a environment, communicating the delegate owner token to the environment and to the resource, and allowing access to the resource by the environment when the environment presents a valid delegate owner token to the resource. In one embodiment, the resource comprises a trusted platform module (TPM).
摘要:
The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method of treating a disease or condition mediated by CDK9.
摘要:
The present invention generally relates to methods for the preparation of compounds that contain imidazole moieties. In some embodiments, the methods include the reaction of a diamine with a dichloroimmonium compound to produce the imidazole moiety. In some embodiments, the methods are employed to prepare compounds having the Formulas II, II or III below: I II III wherein the constituent variables are as described herein.
摘要翻译:本发明一般涉及制备含有咪唑部分的化合物的方法。 在一些实施方案中,所述方法包括二胺与二氯嘧啶化合物的反应以产生咪唑部分。 在一些实施方案中,所述方法用于制备下面具有式II,II或III的化合物:I II III,其中组成变量如本文所述。
摘要:
There are provided compounds according to formula I wherein the substitutents are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia. Also provided are pharmaceutical compositions containing such compounds and processes for preparing some of the compounds of the invention. Other embodiments are also disclosed.