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    Biosensors with porous chromatographic membranes
    42.
    发明授权
    Biosensors with porous chromatographic membranes 失效
    生物传感器与多孔色谱膜

    公开(公告)号：US06726818B2

    公开(公告)日：2004-04-27

    申请号：US09904930

    申请日：2001-07-13

    申请人： Gang Cui ,  Jae Hyun Yoo ,  Byung Wook Woo ,  Moon Hwan Kim ,  Hyun Joon Oh ,  Hakhyun Nam ,  Geun Sig Cha

    发明人： Gang Cui ,  Jae Hyun Yoo ,  Byung Wook Woo ,  Moon Hwan Kim ,  Hyun Joon Oh ,  Hakhyun Nam ,  Geun Sig Cha

    IPC分类号： G01N27327

    CPC分类号： G01N27/3272 ,  C12Q1/004 ,  C12Q1/006 ,  C12Q1/26 ,  G01N30/90 ,  G01N33/491

    摘要： Disclosed is a porous membrane built-in biosensor comprising (a) at least one substrate; (b) an electrode layer patterned on the substrate, consisting of an electrode system and a circuit connector; (c) an insulator, formed on parts of the electrode layer, for electrically separating the electrode system from a circuit connector; and (d) a porous membrane via the insulator on the electrode system, wherein, when a whole blood sample is introduced to the biosensor, the whole blood sample is separated into its components during the chromatographic motion through the porous membrane so that only blood plasma can be contacted with the electrode system. The porous membrane built-in biosensor is provided with a sample inlet, which allows samples to be introduced in a constant quantity to the biosensors porous membranes without pretreatment.

    摘要翻译： 公开了一种内置多孔膜的生物传感器，其包含（a）至少一个基底; （b）在基板上图案化的电极层，由电极系统和电路连接器组成; （c）形成在所述电极层的部分上的用于将所述电极系统与电路连接器电分离的绝缘体; 和（d）通过电极系统上的绝缘体的多孔膜，其中当将全血样品引入生物传感器时，在通过多孔膜进行色谱运动期间将全血样品分离成其组分，使得仅血浆 可以与电极系统接触。 多孔膜内置生物传感器具有样品入口，其允许将样品以恒定量引入生物传感器多孔膜而无需预处理。