利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

47 条记录 (耗时 0.03 秒)

    FLUOROACRYLATE-MULTIFUNCTIONAL ACRYLATE COPOLYMER COMPOSITIONS
    44.
    发明申请
    FLUOROACRYLATE-MULTIFUNCTIONAL ACRYLATE COPOLYMER COMPOSITIONS 有权
    氟代丙烯酸酯多官能丙烯酸酯共聚物组合物

    公开(公告)号：US20080132132A1

    公开(公告)日：2008-06-05

    申请号：US12028589

    申请日：2008-02-08

    申请人： Zai-Ming QIU ,  George G.I. Moore ,  John C. Clark ,  Ramesh C. Kumar

    发明人： Zai-Ming QIU ,  George G.I. Moore ,  John C. Clark ,  Ramesh C. Kumar

    IPC分类号： C08F14/18 ,  B32B27/00 ,  B32B27/04

    CPC分类号： C08F220/38 ,  Y10T428/3154 ,  Y10T442/2311 ,  Y10T442/232 ,  Y10T442/2754

    摘要： A composition comprises a copolymer comprising repeating units derived from at least one co-reactant comprising two or more acrylate groups and repeating units derived from a fluoroacrylate comprising the reaction product of: (a) at least one fluorochemical alcohol represented by the formula: C4F9—X—OH wherein: R=hydrogen or an alkyl group of 1 to 4 carbon atoms, m=2 to 8, Rf=CnF2+1, n=1 to 5, y=0 to 6, and q=1 to 8; (b) at least one unbranched symmetric diisocyanate; and (c) at least one hydroxy-terminated alkyl (meth)acrylate or 2-fluoroacrylate monomer having 2 to about 30 carbon atoms in its alkylene portion; wherein the composition is coatable.

    摘要翻译： 组合物包含共聚物，其包含衍生自至少一种包含两个或更多个丙烯酸酯基团的共反应物的重复单元和衍生自氟代丙烯酸酯的重复单元，所述重复单元包含以下反应产物：（a）至少一种由下式表示的含氟醇： in-line-formula description =“In-line Formulas”end =“lead”？> C 3 -X-OH <？in-line-formula description 其中：R =氢或1至4个碳原子的烷基，m = 2至8，R f = C 1， n = 2〜1，n = 1〜5，y = 0〜6，q = 1〜8; （b）至少一种非支化对称二异氰酸酯; 和（c）至少一种羟基封端的（甲基）丙烯酸烷基酯或其亚烷基部分具有2-30个碳原子的2-氟丙烯酸酯单体; 其中所述组合物是可涂覆的。

    Extended release formulation
    45.
    发明申请
    Extended release formulation 审中-公开
    延长释放配方

    公开(公告)号：US20080124392A1

    公开(公告)日：2008-05-29

    申请号：US12011367

    申请日：2008-01-25

    申请人： Deborah M. Sherman ,  John C. Clark ,  John U. Lamer ,  Steven A. White

    发明人： Deborah M. Sherman ,  John C. Clark ,  John U. Lamer ,  Steven A. White

    IPC分类号： A61K9/62

    CPC分类号： A61K9/1652 ,  A61K9/5047

    摘要： This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.

    摘要翻译： 本发明涉及盐酸文拉法辛的24小时延长释放剂量制剂及其单位剂量形式，抗抑郁药与日常的片剂制剂相比可提供更好的对血浆水平的控制，其必须每天给予两次或更多次，并进一步提供较低的 恶心呕吐发生率高于传统药片。 更具体地说，本发明包括文拉法辛盐酸盐的延长释放制剂，其包含由盐酸文拉法辛，微晶纤维素和任选的用乙基纤维素和羟丙基甲基纤维素的混合物包被的羟丙基甲基纤维素组成的球形体中的治疗有效量的盐酸文拉法星。

    Axial retainer for flow connectors
    47.
    发明授权
    Axial retainer for flow connectors 失效
    用于流动连接器的轴向保持器

    公开(公告)号：US5248306A

    公开(公告)日：1993-09-28

    申请号：US934996

    申请日：1992-08-25

    申请人： John C. Clark ,  William J. Hook ,  Mark E. Larkin

    发明人： John C. Clark ,  William J. Hook ,  Mark E. Larkin

    IPC分类号： A61M39/10

    CPC分类号： A61M39/1011 ,  Y10S604/905

    摘要： A retainer is used in combination with two tubular flow connectors to prevent the inadvertent disconnection of I.V. tubing sets. The retainer includes at least one open collar having a flexible opening so as to be radially and securely attachable adjacent to an increased diameter portion on a tubing connector. A pair of parallel straps connects the collar with an axially pivotable joint so as to facilitates easy manipulation and engagement of the retainer.

    摘要翻译： 保持器与两个管状流动连接器组合使用，以防止IV的意外断开。 管套。 保持器包括至少一个具有柔性开口的敞开的套环，以便与管连接器上的增加的直径部分相邻地径向和牢固地附接。 一对平行带将套环与轴向可枢转接头连接，以便于容易地操纵和接合保持器。