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192 条记录 (耗时 0.077 秒)

    Electronic trading system supporting anonymous negotiation and indications of interest
    41.
    发明授权
    Electronic trading system supporting anonymous negotiation and indications of interest 有权
    电子交易系统支持匿名谈判和兴趣迹象

    公开(公告)号：US08504483B2

    公开(公告)日：2013-08-06

    申请号：US12192253

    申请日：2008-08-15

    申请人： Kevin Foley ,  Kim Bang

    发明人： Kevin Foley ,  Kim Bang

    IPC分类号： H04K1/00 ,  H04L9/00 ,  G06Q40/00

    CPC分类号： G06Q40/04 ,  G06Q20/383

    摘要： A system conducts anonymous negotiations and supports indications of interest in trading stock. The system includes a database for storing public orders received from a public stock trading system; and a server for receiving hidden orders from a plurality of users and for conducting anonymous negotiations between first and second users with the hidden orders. The server repeatedly accesses the database to determine a match of any one of the hidden orders with any one of the public orders, and to execute a pair of orders selected from the hidden orders and the public orders. The system also transmits indications of interest (IOI) into a trading environment using the server for processing a trading order from a first user and for maintaining a profile of a user. The profile includes a current IOI setting for controlling transmission of the IOI from the user. The server responds to a toggle command from the first user to control transmission of the IOI opposite to the current IOI setting. The server responds to the IOI setting being set to allow transmission by transmitting the IOI of the first user associated with the trading order.

    摘要翻译： 一个系统进行匿名谈判，并支持交易股票的兴趣迹象。 该系统包括用于存储从公共股票交易系统接收的公共订单的数据库; 以及服务器，用于从多个用户接收隐藏的命令，以及用隐藏的命令进行第一和第二用户之间的匿名协商。 服务器重复访问数据库以确定任何一个隐藏的订单与任何一个公共订单的匹配，并执行从隐藏订单和公共订单中选择的一对订单。 该系统还使用用于处理来自第一用户的交易订单的服务器将用户感兴趣的指示（IOI）发送到交易环境中并且用于维护用户的简档。 配置文件包括用于控制来自用户的IOI传输的当前IOI设置。 服务器响应来自第一个用户的切换命令来控制与当前IOI设置相反的IOI传输。 服务器响应设置为允许通过传送与交易订单相关联的第一用户的IOI进行传输的IOI设置。

    Spacer with Height and Angle Adjustments for Spacing Vertebral Members
    43.
    发明申请
    Spacer with Height and Angle Adjustments for Spacing Vertebral Members 有权
    间隔脊椎成员的高度和角度调整的间隔

    公开(公告)号：US20110307066A1

    公开(公告)日：2011-12-15

    申请号：US13214822

    申请日：2011-08-22

    申请人： Roy Lim ,  Kevin Foley

    发明人： Roy Lim ,  Kevin Foley

    IPC分类号： A61F2/44

    CPC分类号： A61B17/8858 ,  A61B17/025 ,  A61B2017/0256 ,  A61B2017/2939

    摘要： A device to space vertebral members that may include a deploying device with a first member with an elongated first shaft and a first body at an end of the first shaft, a second member with an elongated second shaft that extends around the first shaft and a second body at an end of the second shaft, and a third member with an elongated third shaft that extends around the second shaft and a third body at an end of the second shaft. The device may include a first plate positioned on a first side of the deploying device, and a second plate positioned on a second side of the deploying device. First, second, and third jointed linkages may be spaced apart along the deploying device and each having a pair of links and each having a first end attached to the first plate, a second end attached to the second plate, and an intermediate joint connecting the pair of links together and being attached to the deploying device.

    摘要翻译： 一种用于将脊椎构件放置的装置，其可以包括具有第一构件的展开装置，所述第一构件具有细长的第一轴和在所述第一轴的端部处的第一主体，具有沿所述第一轴延伸的细长的第二轴的第二构件， 主体在第二轴的端部，以及第三构件，其具有围绕第二轴延伸的细长的第三轴和在第二轴的端部处的第三主体。 该装置可以包括位于展开装置的第一侧上的第一板和位于展开装置的第二侧上的第二板。 第一，第二和第三接合连杆可以沿着展开装置间隔开，并且每个具有一对连杆，并且每个连接件具有连接到第一板的第一端，附接到第二板的第二端和连接到第二板的中间接头 一对链接在一起并被附接到部署设备。

    TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
    46.
    发明申请
    TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY 有权
    调节HSP90活性的三唑化合物

    公开(公告)号：US20100093717A1

    公开(公告)日：2010-04-15

    申请号：US12310150

    申请日：2007-08-14

    申请人： Weiwen Ying ,  Kevin Foley

    发明人： Weiwen Ying ,  Kevin Foley

    IPC分类号： A61K31/4196 ,  A61K31/5377 ,  A61K31/519 ,  A61K31/538 ,  A61K31/428 ,  A61P7/00

    CPC分类号： A61K31/4196 ,  A61K31/423 ,  A61K31/426 ,  A61K31/4439 ,  A61K31/4709 ,  A61K31/472 ,  A61K31/52 ,  A61K31/5377 ,  Y02A50/401

    摘要： The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of treating or inhibiting angiogenesis in a subject in need thereof and methods for blocking, occluding, or otherwise disrupting blood flow in neo vasculature, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.

    摘要翻译： 本发明涉及取代的三唑化合物和包含取代的三唑化合物的组合物。 本发明还涉及在有需要的受试者中治疗或抑制血管生成的方法以及在有需要的受试者中阻断，阻断或以其它方式破坏新脉管系统中的血液流动的方法，其包括向受试者施用取代的三唑化合物 本发明或包含这种化合物的组合物。

    Pyrazole compounds that modulate HSP90 activity
    50.
    发明申请
    Pyrazole compounds that modulate HSP90 activity 有权
    调节HSP90活性的吡唑化合物

    公开(公告)号：US20070191445A1

    公开(公告)日：2007-08-16

    申请号：US11502346

    申请日：2006-08-10

    申请人： Weiwen Ying ,  Shijie Zhang ,  Zhenjian Du ,  Kevin Foley

    发明人： Weiwen Ying ,  Shijie Zhang ,  Zhenjian Du ,  Kevin Foley

    IPC分类号： A61K31/4184 ,  A61K31/416 ,  A61K31/4152 ,  C07D403/02

    CPC分类号： C07D231/20 ,  C07D231/18 ,  C07D231/38 ,  C07D403/04

    摘要： Compounds of formula (I), pharmaceutical compositions comprising compounds of formula (I) and methods of inhibiting Hsp90 in a cell, treating or preventing a proliferation disorder in a mammal and treating cancer in a mammal comprising administering a compound of formula (I) to a patient or a cell. Variable R5 is an optionally substituted heteroaryl; an optionally substituted 6 to 14-membered aryl; a bicyclic 9-member heterocycle optionally substituted at any substitutable nitrogen or carbon atoms; or a substituent R18, defined herein. Ring A is an aryl or a heteroaryl optionally further substituted with one or more substituents in addition to R3. Substituent R3 is defined herein.

    摘要翻译： 式（I）化合物，包含式（I）化合物的药物组合物和抑制细胞中Hsp90的方法，治疗或预防哺乳动物中的增殖病症并治疗哺乳动物的癌症，其包括给予式（I）化合物至 患者或细胞。 可变的R 5是任选取代的杂芳基; 任选取代的6至14元芳基; 任选在任何可取代的氮或碳原子上取代的双环9元杂环; 或本文定义的取代基R 18。 环A是芳基或杂芳基，除了R 3以外，还可被一个或多个取代基进一步取代。 取代基R 3在本文中定义。