公开(公告)号：US20060166326A1

公开(公告)日：2006-07-27

申请号：US11335810

申请日：2006-01-19

申请人： Rachel Meyers ,  William Cook ,  Mark Williamson ,  Laura Rudolph-Owen ,  Ruth Gimeno

发明人： Rachel Meyers ,  William Cook ,  Mark Williamson ,  Laura Rudolph-Owen ,  Ruth Gimeno

IPC分类号： C07H21/04 ,  C12P21/06 ,  C12N9/04

CPC分类号： C12N9/0004 ,  C07K2319/00 ,  C12N9/0006

摘要： The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

公开(公告)号：US20050206067A1

公开(公告)日：2005-09-22

申请号：US10803822

申请日：2004-03-18

申请人： William Cook ,  Edward Triplett

发明人： William Cook ,  Edward Triplett

IPC分类号： B65H5/06

CPC分类号： B65H3/0684 ,  B65H3/0669 ,  B65H5/062 ,  B65H2403/40 ,  B65H2403/422

摘要： A device and method for moving media sheets within an image forming apparatus. The device includes a motor; a pick mechanism operatively connected to the motor, a first gear set having a first ratio and operatively connecting the motor to the pick mechanism, a feed nip operatively connected to the motor to receive the media sheet and forward the media sheet along a media path, and a second gear set having a second gear ratio and operatively connecting the motor to the feed nip. The motor may operate at a constant speed and drive the pick mechanism at a first speed and the feed nip at a second speed. The first and second speeds may be the same, or the speeds may be different.

摘要翻译： 一种用于在图像形成装置内移动介质片的装置和方法。 该装置包括马达; 可操作地连接到电动机的拾取机构，具有第一比率并且可操作地将电动机连接到拾取机构的第一齿轮组，可操作地连接到电动机以接收介质片并且沿着介质路径转动介质片的进给辊隙， 以及具有第二齿轮比并且可操作地将马达连接到进给压区的第二齿轮组。 电机可以以恒定的速度运行，并以第一速度驱动拾取机构，并以第二速度驱动进给压区。 第一和第二速度可以相同，或者速度可能不同。

公开(公告)号：US20050155912A1

公开(公告)日：2005-07-21

申请号：US10753231

申请日：2004-01-07

申请人： Lawrence Carvagno ,  William Cook ,  Ronald Dailey ,  Jacob Southerland

发明人： Lawrence Carvagno ,  William Cook ,  Ronald Dailey ,  Jacob Southerland

IPC分类号： B07B4/02 ,  B07B7/04 ,  B07B7/00

CPC分类号： B07B7/04 ,  B07B4/02

摘要： A classifier for classifying particulates entrained in a flowing stream of gas is configured such that a change of direction of gas flow causes particles to impinge upon a target, heavier particles being trapped in a downwardly extending fluidized trap. The classifier is easily constructed, has no moving parts, and can take the place of sifters and other equipment traditionally used for classifying such product streams.

摘要翻译： 用于分选夹带在流动气流中的颗粒的分级器被配置为使得气流的方向的改变导致颗粒撞击目标，较重的颗粒被捕获在向下延伸的流化阱中。 分类器易于构造，没有移动部件，可以代替传统上用于分类这种产品流的筛分机和其他设备。

公开(公告)号：USD502995S1

公开(公告)日：2005-03-15

申请号：US29188757

申请日：2003-08-21

申请人： William Cook ,  Mark Herman

设计人： William Cook ,  Mark Herman

公开(公告)号：US20050046651A1

公开(公告)日：2005-03-03

申请号：US10651238

申请日：2003-08-28

申请人： Benjamin Askren ,  Robert Burdick ,  Bill Chappel ,  Christopher Chee ,  William Cook ,  David Cseledy ,  Larry Foster ,  James Harden ,  William Klein

发明人： Benjamin Askren ,  Robert Burdick ,  Bill Chappel ,  Christopher Chee ,  William Cook ,  David Cseledy ,  Larry Foster ,  James Harden ,  William Klein

IPC分类号： B41J2/005 ,  B41J2/045 ,  B41J29/38

CPC分类号： B41J19/16 ,  B41J2/0057 ,  B41J2/04505 ,  B41J2/0451 ,  B41J2/04543 ,  B41J2/04573 ,  B41J2/0458

摘要： An apparatus and method for ink-jet printing onto an intermediate drum in a helical pattern while correcting for image skew and aliasing. A plurality of ink-jet print heads place an image on an intermediate drum, impervious to ink, in a helical patter. To compensate for helical printing, the image is altered by nozzle placement and image manipulation to correct for skewing errors, and thereafter, the nozzle timing is adjusted to correct for aliasing. The plurality of print heads move parallel to the axis of rotation of the drum while the drum is simultaneously rotating, causing the image to be placed in a helical pattern. Once the entire image is placed on the drum, paper is rolled against the drum under pressure and the image is transferred thereto.

摘要翻译： 一种用于在校正图像偏斜和混叠的同时以螺旋图案在中间滚筒上喷墨打印的装置和方法。 多个喷墨打印头以螺旋图案将图像放置在不透墨水的中间滚筒上。 为了补偿螺旋印刷，通过喷嘴放置和图像操作改变图像以校正偏斜误差，此后，调整喷嘴正时以校正混叠。 多个打印头在滚筒同时旋转的同时平行于滚筒的旋转轴线移动，从而使图像以螺旋状的方式放置。 一旦将整个图像放置在滚筒上，纸张在压力下滚动滚筒并将图像转印到其上。

公开(公告)号：US4890623A

公开(公告)日：1990-01-02

申请号：US167878

申请日：1988-03-14

申请人： William Cook ,  Jack Herman ,  Donald Rowe ,  John Sylvanowicz

发明人： William Cook ,  Jack Herman ,  Donald Rowe ,  John Sylvanowicz

IPC分类号： A61B5/042

CPC分类号： A61B5/6853 ,  A61B5/042 ,  A61B5/0422 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/08 ,  A61B2562/164 ,  Y10T29/49128

摘要： A printed circuit biopotential sensing device is provided which is particularly adapted for endocardial or other deep body applications. The device has a predetermined printed circuit pattern formed on a thin film substrate, the pattern having at least one electrode pad at its distal end, at least one terminal pad at the proximal end, and conductor means selectively interconnecting the electrode pads and terminal pads. The substrate is secured to, and is preferably wrapped around an elongated member which is preferably tube-shaped in a manner such that the electrodes are exposed at the distal end of the member, and the terminal pads at the proximal end of the substrate are utilized in forming a suitable connector from the device. By forming the conductors on only a selected fraction of the width of the substrate and overlapping the portion of the substrate containing the conductors during the helical wrapping process, the substrate insulates and protects the conductors and eliminates the need for a separate protective layer. The device may, for example, be a percutaneous catheter with the electrodes being formed at the distal end thereof, or may be a sensing probe which includes a sensing support member, such as a solid plastic member or a balloon which has the distal end of the substrate containing the electrode pads secured thereto.

摘要翻译： 提供了一种特别适用于心内膜或其他深体应用的印刷电路生物电位感测装置。 该装置具有形成在薄膜基板上的预定印刷电路图案，该图案在其远端具有至少一个电极焊盘，在该近端具有至少一个端子焊盘，导体装置选择性地将电极焊盘和端子焊盘互连。 衬底被固定并且优选地缠绕在细长构件周围，细长构件优选地是以管状形状的，使得电极在构件的远端处暴露，并且利用衬底的近端处的端子衬垫 从该装置形成合适的连接器。 通过仅在衬底的宽度的选定部分形成导体，并且在螺旋缠绕过程期间与包含导体的衬底的部分重叠，衬底绝缘并保护导体，并且不需要单独的保护层。 该装置可以是例如具有电极形成在其远端处的经皮导管，或者可以是感测探头，其包括感测支撑构件，例如固体塑料构件或气囊，其具有远端 所述基板包含固定到其上的电极焊盘。