公开(公告)号：US07238868B2

公开(公告)日：2007-07-03

申请号：US10616167

申请日：2003-07-09

申请人： Shigeru Muramatsu ,  Kiyoshi Kawamura

发明人： Shigeru Muramatsu ,  Kiyoshi Kawamura

IPC分类号： G10F1/02

CPC分类号： G10F1/02

摘要： An automatic player piano is broken down into an acoustic piano and an automatic playing system, and solenoid-operated key actuators are driven to rotate the black/white keys of the acoustic piano; the space between the keyboard and the array of black/white keys is so narrow that the manufacturer provides the solenoid-operated key actuators in the space below the key bed; plunger holes are formed in the rear portion of the key bed, and the solenoids occupy the space under the key bed so that the plungers project through the plunger holes into the space beneath the rear portions of the keys; the key bed is does not lose the mechanical strength so that the tuning work is not frequently required for the key action units.

摘要翻译： 自动演奏钢琴分为声学钢琴和自动演奏系统，驱动电磁操作的钥匙执行器旋转原声钢琴的黑/白键; 键盘和黑/白键阵列之间的空间如此狭窄，使得制造商在钥匙床下方的空间内提供电磁操作的钥匙致动器; 柱塞孔形成在钥匙床的后部，螺线管占据钥匙床下面的空间，使得柱塞从柱塞孔突出到钥匙后部的空间内; 钥匙床不会失去机械强度，因此关键动作单元不需要调整工作。

公开(公告)号：US06686373B2

公开(公告)日：2004-02-03

申请号：US10191593

申请日：2002-07-09

申请人： Kiyoshi Kawamura ,  Sachiko Mihara ,  Seiji Nukui ,  Chikara Uchida

发明人： Kiyoshi Kawamura ,  Sachiko Mihara ,  Seiji Nukui ,  Chikara Uchida

IPC分类号： A61K314745

CPC分类号： C07D471/04

摘要： This invention provides a compound of the formula (I): or the pharmaceutically acceptable salts thereof wherein the dashed lines represent optional double bonds; C1, C2, C3 and C4 are carbon atom; R1 is C1-4 alkyl; R2 is H, amino, etc.; R3 is H, halo-CH2—, C2-8 alkyl or Q1-, wherein said C2-8 alkyl is optionally substituted with up to 3 substituents selected from halo, C1-3 alkyl, R4(R5)N, etc.; R4 is H, C1-7 alkyl, etc.; R5 is H, C1-7alkyl, etc.; R6 and R7 are independently selected from H and C1-4 alkyl; R8 is aryl or heteroaryl; Q1 is a 4-12 membered monocyclic or bicyclic aromatic, partially saturated or fully saturated ring optionally containing up to 4 heteroatoms selected from O, N and S, and is optionally substituted with halo, C1-4 alkyl, etc.; Y5, Y6, Y7 and Y8 are hydrogen; Y1, Y2, Y3 and Y4 are independently selected from hydrogen, halo, etc.; Q2 is a 5-12 membered monocyclic or bicyclic aromatic, partially saturated or fully saturated ring optionally containing up to 3 heteroatoms selected from O, N and S, and is optionally substituted with halo, C1-4alkyl-, etc.; These compounds have protein kinase C inhibitory activity and thus are useful for the treatment of neuropathic pain, acute or chronic inflammatory pain, auditory deficiency (synaptic repair), or the like in mammalian, especially humans. This invention also provides a pharmaceutical composition comprising the above compound.

摘要翻译： 本发明提供式（I）化合物或其药学上可接受的盐，其中虚线表示任选的双键; C 1，C 2，C 3和C 4是碳原子; R 1是C 1-4烷基; R 2是H，氨基等; R 3是H，卤代-CH 2 - ，C 2-8烷基或Q 1 - ，其中所述C 2-8烷基任选被至多3个选自卤素，C 1-3烷基，R 4， （R 5）N等; R 4是H，C 1-7烷基等; R 5是H，C 1-7烷基等; R 6和R 7独立地选自H和C 1-4烷基; R 8是芳基或杂芳基; Q 1是4-12元单环或双环芳族，部分饱和或完全饱和的环，任选地含有至多4个选自O，N和S的杂原子，并且任选地被卤素，C 1-4烷基等取代; Y 5，Y 6，Y 7和Y 8是氢; Y 1，Y 2，Y 3和Y 4独立地选自氢，卤素等; Q 2是5-12元单环或双环芳族，部分饱和或完全饱和的环，任选地含有至多3个选自O，N和S的杂原子，并且任选被卤素，C 1-4烷基等取代; 这些化合物具有蛋白激酶C抑制活性，因此可用于治疗哺乳动物，特别是人类的神经性疼痛，急性或慢性炎性疼痛，听觉缺陷（突触修复）等。 本发明还提供了包含上述化合物的药物组合物。

公开(公告)号：US06683242B2

公开(公告)日：2004-01-27

申请号：US10085603

申请日：2002-02-26

申请人： Satoshi Inoue ,  Kiyoshi Kawamura

发明人： Satoshi Inoue ,  Kiyoshi Kawamura

IPC分类号： G10A132

CPC分类号： G10C5/005 ,  G10H1/346

摘要： A silent piano is a composite keyboard musical instrument fabricated on the basis of an acoustic piano, and a pianist plays a tune by piano tones or electronic tones; when the pianist selects the electronic tones, a hammer stopper enters the trajectories of hammers, and a tandem regulating button mechanism changes damping columns onto the trajectories of jacks in such a manner that the jack is brought into contact with the damping column concurrently with a regulating button; since the damping columns are closer to the jack than the regulating buttons, the jack turns at a larger angular velocity so that the hammer is not pinched between the jack and the hammer stopper; the damping columns are moved onto a virtual plane where the regulating buttons are so that the jacks are commonly used between the silent piano and the standard acoustic piano.

摘要翻译： 无声钢琴是在原声钢琴的基础上制作的复合键盘乐器，钢琴家用钢琴音调或电子音调演奏曲调; 当钢琴家选择电子音调时，琴槌挡块进入锤的轨迹，并且串联调节按钮机构将阻尼柱改变成插孔的轨迹，使得千斤顶与调节器同时与阻尼柱接触 按钮 由于阻尼柱比调节按钮更靠近千斤顶，所以千斤顶以较大的角速度转动，使得锤不夹在千斤顶和锤塞之间; 阻尼柱被移动到虚拟平面上，其中调节按钮使得在静音钢琴和标准声学钢琴之间通常使用插孔。

公开(公告)号：US06403872B2

公开(公告)日：2002-06-11

申请号：US09737615

申请日：2000-12-13

申请人： Shigeru Muramatsu ,  Yasuhiko Oba ,  Tadaharu Kato ,  Kiyoshi Kawamura

发明人： Shigeru Muramatsu ,  Yasuhiko Oba ,  Tadaharu Kato ,  Kiyoshi Kawamura

IPC分类号： G10H306

CPC分类号： G10H1/346 ,  G01P3/36 ,  G10F1/02 ,  G10G3/04 ,  G10H2220/305

摘要： An automatic player piano is an acoustic piano equipped with a data acquisition system and a playback system, and the data acquisition system monitors the hammers with hammer sensors for producing a set of music data codes representative of a performance on the keyboard, wherein the hammer sensor has a detectable range over the trajectory of the associated hammer so that the data acquisition system obtains pieces of music data accurately representative of the trajectory of hammer to be required for a faithful reproduction of the original performance.

摘要翻译： 自动演奏器钢琴是配备有数据采集系统和回放系统的原声钢琴，数据采集系统用锤传感器监测锤子，用于产生代表键盘性能的一组音乐数据代码，其中锤传感器 在相关联的锤的轨迹上具有可检测范围，使得数据采集系统获得准确代表为了忠实地再现原始性能而需要的锤的轨迹的音乐数据片段。

公开(公告)号：US06300363B1

公开(公告)日：2001-10-09

申请号：US09424837

申请日：1999-12-03

申请人： Rodney William Stevens ,  Kasumari Nakao ,  Kiyoshi Kawamura ,  Chikara Uchida ,  Shinya Fujiwara

发明人： Rodney William Stevens ,  Kasumari Nakao ,  Kiyoshi Kawamura ,  Chikara Uchida ,  Shinya Fujiwara

IPC分类号： A61K3140

CPC分类号： C07D401/06 ,  C07D209/40 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/06 ,  C07D409/12 ,  C07D413/06 ,  C07D413/12 ,  C07D417/06 ,  C07D417/12

摘要： This invention provides a compound of the following formula: and the pharmaceutically acceptable salts thereof, wherein L is oxygen or sulfur; Y is a direct bond or C1-4 alkylidene; Q is C1-6 alkyl, C3-7 cycloalkyl, phenyl, naphthyl, heteroaryl or the like; R1 is hydrogen, C1-6 alkyl or the like; R2 is hydrogen, C1-4 alkyl, C(O)R5 wherein R5 is C1-22 alkyl or C2-22 alkenyl, halosubstituted C1-8 alkyl, halosubstituted C2-8alkenyl, —Y—C3-7 cycloalkyl, —Y—C3-7 cycloalkenyl, phenyl, naphthyl, heteroaryl or the like; X is halo, C1-4 alkyl, hydroxy, C1-4 alkoxy or the like; and n is 0, 1, 2 or 3, with the proviso that a group of formula —Y—Q is not methyl or ethyl when X is hydrogen; L is oxygen; R1 is hydrogen; and R2 is acetyl. This invention also provides a pharmaceutical composition useful for the treatment of a medical condition in which prostaglandins are implicated as pathogens.

摘要翻译： 本发明提供下式的化合物及其药学上可接受的盐，其中L是氧或硫; Y是直接键或C1-4亚烷基; Q为C 1-6烷基，C 3-7环烷基，苯基，萘基，杂芳基等; R1是氢，C1-6烷基等; R2是氢，C1-4烷基，C（O）R5，其中R5是C1-22烷基或C2-22链烯基，卤代C 1-8烷基，卤代C 2-8烯基，-Y-C 3-7环烷基，-Y-C 3 -7环烯基，苯基，萘基，杂芳基等; X是卤素，C 1-4烷基，羟基，C 1-4烷氧基等; 且n为0,1,2或3，条件是当X为氢时，式-Y-Q基团不是甲基或乙基; L是氧; R1是氢; 并且R 2是乙酰基。本发明还提供了可用于治疗前列腺素作为病原体的医学病症的药物组合物。

公开(公告)号：US6084167A

公开(公告)日：2000-07-04

申请号：US934105

申请日：1997-09-19

申请人： Teruo Akimoto ,  Kiyoshi Kawamura ,  Taro Kawabata ,  Yasuhiko Ohba ,  Tadaharu Kato ,  Masaaki Suzuki ,  Motoya Kondo ,  Hironori Osakabe

发明人： Teruo Akimoto ,  Kiyoshi Kawamura ,  Taro Kawabata ,  Yasuhiko Ohba ,  Tadaharu Kato ,  Masaaki Suzuki ,  Motoya Kondo ,  Hironori Osakabe

IPC分类号： G09B15/00 ,  G10C1/02 ,  G10C3/00 ,  G10H1/32 ,  H04N5/445 ,  H04N5/64 ,  G09B15/02

CPC分类号： G10C3/00 ,  G10H1/32

摘要： A keyboard instrument is configured such that a flat panel-like display unit such as a liquid crystal display for displaying character information and/or images is provided on an instrument main body and that speakers, a recording/reproducing unit for multi media such as sound and/or image recording media, a microphone and a "karaoke" reproduction unit are connected to the display unit so as to improve the function of displaying a notation and/or lyric at the time of a performance, a performance function such as an ensemble performance or "karaoke" performance, and a tuning function.

摘要翻译： 键盘乐器被配置为使得诸如用于显示字符信息和/或图像的液晶显示器的平板显示单元设置在乐器主体上，并且扬声器，诸如声音的多媒体的记录/再现单元 和/或图像记录介质，麦克风和“卡拉OK”再现单元连接到显示单元，以便提高在演奏时显示符号和/或歌词的功能，诸如集合的演奏功能 表演或“卡拉OK”表演，以及调谐功能。

公开(公告)号：US5874687A

公开(公告)日：1999-02-23

申请号：US318979

申请日：1994-10-06

申请人： Kiyoshi Kawamura

发明人： Kiyoshi Kawamura

IPC分类号： G10C3/16 ,  G10C5/00 ,  G10H1/34 ,  G10C3/00 ,  G10C3/18

CPC分类号： G10C3/161 ,  G10C5/005 ,  G10H1/346

摘要： a stopper, a driver unit, key and pedal sensors, a sound processing unit and a sound system are installed in an acoustic piano so as to remodel the acoustic piano into a keyboard musical instrument performable with either acoustic or electronic sounds.

摘要翻译： 声学钢琴中安装有塞子，驱动单元，键和踏板传感器，声音处理单元和声音系统，以便将声学钢琴改造成可以用声音或电子声音执行的键盘乐器。

公开(公告)号：US5679961A

公开(公告)日：1997-10-21

申请号：US526901

申请日：1995-09-12

申请人： Hitoshi Higurashi ,  Akira Toriumi ,  Fumiko Yamaguchi ,  Kiyoshi Kawamura ,  Alfred Hubler

发明人： Hitoshi Higurashi ,  Akira Toriumi ,  Fumiko Yamaguchi ,  Kiyoshi Kawamura ,  Alfred Hubler

IPC分类号： H01L29/12 ,  H01L29/76 ,  H01L29/06

CPC分类号： B82Y10/00 ,  H01L29/127 ,  H01L29/7613

摘要： According to the present invention, there is provided a correlation tunnel device capable of achieving a low power consumption without decreasing a drive force when a large-scale-integrated circuit is constituted. A correlation tunnel device according to the present invention comprises a first quantum dot structure including a first carrier confinement region having at least two discrete energy levels, a carrier conduction region adjacent to the first carrier confinement region, and a tunnel barrier arranged only between the first carrier confinement region and the conduction region, and a second quantum dot structure including a second carrier confinement region having at least two discrete energy levels, a carrier conduction region adjacent to the second carrier confinement region, and a tunnel barrier arranged only between the second carrier confinement region and the conduction region, wherein an energy level occupied by the carrier in the first carrier confinement region and an energy level occupied by the carrier in the second carrier confinement region have a correlation.

摘要翻译： 根据本发明，提供了一种能够在构成大型集成电路时不降低驱动力的同时实现低功耗的相关隧道装置。 根据本发明的相关隧道装置包括第一量子点结构，其包括具有至少两个离散能级的第一载流子限制区域，与第一载流子限制区域相邻的载流子传导区域，以及仅在第一 载流子限制区域和导电区域，以及包括具有至少两个离散能级的第二载流子限制区域的第二量子点结构，与第二载流子限制区域相邻的载流子导电区域，以及仅在第二载流子 限制区域和导电区域，其中由第一载流子限制区域中的载流子占据的能级和第二载流子限制区域中的载流子所占据的能级具有相关性。

公开(公告)号：US5610356A

公开(公告)日：1997-03-11

申请号：US503527

申请日：1995-07-18

申请人： Shinya Koseki ,  Kiyoshi Kawamura

发明人： Shinya Koseki ,  Kiyoshi Kawamura

IPC分类号： G10C3/16 ,  G10C5/00 ,  G10H1/34 ,  G10C3/12 ,  G10D15/00

CPC分类号： G10C5/005

摘要： A keyboard musical instrument selectively enters into an acoustic sound mode for generating acoustic piano tones and an electronic sound mode for generating electronic sounds instead of the acoustic piano tones, and a stopper is changed between a free position and a blocking position by an actuator controlled through detection with photo-interrupters, thereby eliminating aged deterioration from the position control between the free position and the blocking position.

摘要翻译： 键盘乐器选择性地进入用于产生声学钢琴音调的声学声音模式和用于产生电子声音而不是原声钢琴音调的电子声音模式，并且通过控制的致动器在自由位置和阻挡位置之间改变止动器 利用光电断路器进行检测，从而消除位置控制在自由位置和阻挡位置之间的老化劣化。

公开(公告)号：US5602351A

公开(公告)日：1997-02-11

申请号：US174179

申请日：1993-12-27

申请人： Kiyoshi Kawamura ,  Yasutoshi Kaneko

发明人： Kiyoshi Kawamura ,  Yasutoshi Kaneko

IPC分类号： G10C1/04 ,  G10C3/16 ,  G10C5/00 ,  G10D15/00

CPC分类号： G10C5/005

摘要： A piano-like keyboard instrument allowing a player to perform in either an acoustic sound mode and or an electronic sound producing mode. In the electronic sound producing mode, a stopper blocks sets of piano strings from hammers and an electronic sound producing unit generates electronic sounds. A key touch is maintained in the electronic sound producing mode. A gap regulating unit changes gaps between the toes of jacks and regulating buttons, depending upon which mode of operation is selected. Hammer shanks rebound on the stopper after the escapes of the jacks.

摘要翻译： 一种钢琴般的键盘乐器，允许玩家以声音模式或电子声音产生模式进行演奏。 在电子声音产生模式中，止动器阻挡来自锤子的琴弦组，电子声音产生单元产生电子声音。 在电子声音产生模式中保持关键触摸。 间隙调节单元根据选择的操作模式改变千斤顶和调节按钮的脚趾之间的间隙。 千斤顶逃跑后，锤子在塞子上反弹。