公开(公告)号：US06697123B2

公开(公告)日：2004-02-24

申请号：US09822442

申请日：2001-03-30

申请人： Angel Janevski ,  Nevenka Dimitrova

发明人： Angel Janevski ,  Nevenka Dimitrova

IPC分类号： H04N545

CPC分类号： H04N5/45 ,  H04N21/4312 ,  H04N21/4316 ,  H04N21/44008 ,  H04N21/4622

摘要： In a television receiver having Picture-In-Picture (PIP), a controller analyzes the content of an auxiliary video signal forming a PIP image, and automatically adjusts the shape and transparency of the PIP image in accordance with the content of the auxiliary video signal.

摘要翻译： 在具有画中画（PIP）的电视接收机中，控制器分析形成PIP图像的辅助视频信号的内容，并且根据辅助视频信号的内容自动调整PIP图像的形状和透明度 。

公开(公告)号：US06654067B1

公开(公告)日：2003-11-25

申请号：US09477083

申请日：1999-12-30

申请人： Thomas Mc Gee ,  Nevenka Dimitrova

发明人： Thomas Mc Gee ,  Nevenka Dimitrova

IPC分类号： H04N514

CPC分类号： G06F17/30802 ,  G06F17/30814 ,  G06F17/30843 ,  H04N5/147

摘要： To prevent undesired images from appearing in moving video images, short-duration portions of video information contained within longer video works are detected and reported by, for example, displaying the short-duration portions on a monitor. These short-duration portions are detected, for example, by locating scene cuts, region cuts, or object cuts that occur in rapid succession.

摘要翻译： 为了防止在移动视频图像中出现不期望的图像，通过例如在监视器上显示短时间部分来检测和报告更长视频作品中包含的视频信息的短时间部分。 例如，通过定位快速连续发生的场景切割，区域切割或物体切割来检测这些短时间部分。

公开(公告)号：US08949878B2

公开(公告)日：2015-02-03

申请号：US09822436

申请日：2001-03-30

申请人： Nevenka Dimitrova ,  Radu Jasinschi

发明人： Nevenka Dimitrova ,  Radu Jasinschi

IPC分类号： H04N7/16 ,  H04N21/466 ,  H04N21/439 ,  H04N21/44 ,  H04N21/454 ,  H04N21/475

CPC分类号： H04N21/466 ,  H04N7/163 ,  H04N21/4394 ,  H04N21/44008 ,  H04N21/4542 ,  H04N21/4755

摘要： A parental control system provides the ability to automatically filter a multimedia program content in real time based on stock and user specified criteria. The criteria are used to teach a learning module in the system what types of video program segments are to be considered sensitive or objectionable so that the module's understanding of what is sensitive and what is not can be applied to other video programs to provide real-time filtering. The multimedia program is broken down into audio, video, and transcript components so that sound effects, visual components and objects, and language can all be analyzed collectively to make a determination of whether offending material is being passed along in the multimedia program. The user has the option of training the system for any type of objectionable material, not just sex and violence.

公开(公告)号：US20140040264A1

公开(公告)日：2014-02-06

申请号：US13983651

申请日：2012-01-30

申请人： Vinay Varadan ,  Prateek Mittal ,  Sitharthan Kamalakaran ,  Nevenka Dimitrova ,  Angel Janevski ,  Nilanjana Banerjee

发明人： Vinay Varadan ,  Prateek Mittal ,  Sitharthan Kamalakaran ,  Nevenka Dimitrova ,  Angel Janevski ,  Nilanjana Banerjee

IPC分类号： G06F19/00

CPC分类号： G06F19/324 ,  G16B5/00 ,  G16B25/00 ,  G16B40/00

摘要： The present invention relates to a method for stratifying a patient into a clinically relevant group comprising the identification of the probability of an alteration within one or more sets of molecular data from a patient sample in comparison to a database of molecular data of known phenotypes, the inference of the activity of a biological network on the basis of the probabilities, the identification of a network information flow probability for the patient via the probability of interactions in the network, the creation of multiple instances of network information flow for the patient sample and the calculation of the distance of the patient from other subjects in a patient database using multiple instances of the network information flow. The invention further relates to a biomedical marker or group of biomedical markers associated with a high likelihood of responsiveness of a subject to a cancer therapy wherein the biomedical marker or group of biomedical markers comprises altered biological pathway markers, as well as to an assay for detecting, diagnosing, graduating, monitoring or prognosticating a medical condition, or for detecting, diagnosing, monitoring or prognosticating the responsiveness of a subject to a therapy against said medical condition, in particular ovarian cancer. Furthermore, a corresponding clinical decision support system is provided.

摘要翻译： 本发明涉及一种用于将患者分层为临床相关组的方法，其包括鉴定来自患者样品的一组或多组分子数据内的改变概率与已知表型的分子数据的数据库相比较， 基于概率推断生物网络的活动，通过网络中的交互概率识别患者的网络信息流概率，创建患者样本的多个网络信息流实例和 使用网络信息流的多个实例来计算患者与患者数据库中的其他受试者的距离。 本发明进一步涉及生物医学标记物或生物医学标记物组，其与受试者对癌症治疗的响应性的高可能性相关联，其中生物医学标记物或生物医学标记物组包括改变的生物学途径标志物，以及用于检测 ，诊断，毕业，监测或预测医学状况，或用于检测，诊断，监测或预测受试者对于针对所述医学病症，特别是卵巢癌的治疗的反应性。 此外，提供了相应的临床决策支持系统。

公开(公告)号：US20130226621A1

公开(公告)日：2013-08-29

申请号：US13881512

申请日：2011-10-24

申请人： Pieter Jan Van Der Zaag ,  Nevenka Dimitrova ,  Anja Van De Stolpe ,  Hendrik Van Houten

发明人： Pieter Jan Van Der Zaag ,  Nevenka Dimitrova ,  Anja Van De Stolpe ,  Hendrik Van Houten

IPC分类号： G06Q20/10 ,  G06Q50/22

CPC分类号： G06Q20/10 ,  G06Q10/00 ,  G06Q50/22 ,  G16B20/00 ,  G16H40/20 ,  G16H40/63

摘要： A method comprises: recording an electronic record of diagnostic events including the performing of in-vitro diagnostic tests; during the recording, identifying the performing of a licensed in-vitro diagnostic test for which license information is stored in a licenses database; and computing license compensation due to a licensor for the performing of the licensed in-vitro diagnostic test based on royalty calculation information stored in the licenses database. The recording, identifying, and computing operations are performed by one or more computers. The method may further include remitting the computed license compensation to the licensor, the remitting also being performed by one or more computers. The licensed in-vitro diagnostic test may comprise a licensed biomarker test, for example one obtained by DNA or RNA sequencing, and the method may further comprise: performing the licensed biomarker test using a genome sequencer, wherein the performing of the licensed biomarker test and the computing of license compensation are both performed at a single medical facility.

摘要翻译： 一种方法包括：记录诊断事件的电子记录，包括进行体外诊断测试; 在记录期间，识别许可证体验诊断测试的执行，许可信息被存储在许可证数据库中; 以及根据许可人根据存储在许可证数据库中的版税计算信息执行许可的体外诊断测试来计算许可证补偿。 记录，识别和计算操作由一个或多个计算机执行。 该方法还可以包括将所计算的许可证补偿递交给许可方，还由一个或多个计算机执行。 许可的体外诊断测试可以包括许可的生物标志物测试，例如通过DNA或RNA测序获得的测试，并且该方法还可以包括：使用基因组测序仪进行许可的生物标志物测试，其中执行许可的生物标志物测试和 许可证补偿的计算都在单一医疗机构进行。

公开(公告)号：US08261306B2

公开(公告)日：2012-09-04

申请号：US10014258

申请日：2001-12-11

申请人： Nevenka Dimitrova ,  John D. Zimmerman ,  Radu Serban Jasinschi

发明人： Nevenka Dimitrova ,  John D. Zimmerman ,  Radu Serban Jasinschi

IPC分类号： G06F3/00

CPC分类号： H04N21/2542 ,  G06Q30/02 ,  H04N5/44543 ,  H04N7/17318 ,  H04N21/25891 ,  H04N21/2668 ,  H04N21/4532 ,  H04N21/4622 ,  H04N21/472 ,  H04N21/4725 ,  H04N21/47815 ,  H04N21/8586

摘要： A system and method for providing information to television viewers in order to assist them in shopping from an apparently conventional media, such as a television program, as well as making better and more educated shopping decisions are provided. The user selects the product of interest, and if desired, indicates the price, quantity and time frame within which he/she wants to buy the product. The system then acts as an agent on the user's behalf to get the best product under best price and shortest time frame as may be desired. When a user sees a product he wants while watching television, he simply can press a point on the screen, talk, or press a button on a remote control or similar keypad and the system shows the current price and availability. If the user wants the product, he can buy it instantly. If the user determines it to be too expensive, he can add the product to his wish-list with a price he would be willing to pay.

摘要翻译： 提供了一种用于向电视观众提供信息以便帮助他们从诸如电视节目的明显传统媒体购物以及做出更好和更受教育的购物决定的信息的系统和方法。 用户选择感兴趣的产品，如果需要，表示他/她想要购买产品的价格，数量和时间范围。 该系统然后代表用户代理，以最佳价格和最短的时间框架获得最佳产品。 当用户在看电视时看到他想要的产品时，他只需按屏幕上的一个点，说话或按遥控器或类似键盘上的按钮，系统显示当前的价格和可用性。 如果用户想要产品，他可以立即购买。 如果用户确定它太贵了，他可以以他愿意支付的价格将产品添加到他的愿望清单中。

公开(公告)号：US20120036116A1

公开(公告)日：2012-02-09

申请号：US13129412

申请日：2009-11-11

申请人： Srinivas Rao Kudavelly ,  Nevenka Dimitrova

发明人： Srinivas Rao Kudavelly ,  Nevenka Dimitrova

IPC分类号： G06F17/30

CPC分类号： G16B30/00 ,  G16B40/00 ,  G16B50/00

摘要： The present invention discloses a method for DNA sequence analysis based on DNA spectrogram database. Furthermore, a use, a device and a computer-readable medium related to the method are disclosed.

摘要翻译： 本发明公开了一种基于DNA谱图数据库的DNA序列分析方法。 此外，公开了与该方法相关的使用，设备和计算机可读介质。

公开(公告)号：US20110246082A1

公开(公告)日：2011-10-06

申请号：US12995678

申请日：2009-06-12

申请人： Anca Ioana Daniela Bucur ,  Jasper Johannes Adrianus Van Leeuwen ,  Nevenka Dimitrova ,  Chetan Mittal

发明人： Anca Ioana Daniela Bucur ,  Jasper Johannes Adrianus Van Leeuwen ,  Nevenka Dimitrova ,  Chetan Mittal

IPC分类号： G06F19/00

CPC分类号： G16B30/00 ,  G16B40/00 ,  G16B45/00

摘要： The present invention relates a method for analyzing a DNA sequence. The DNA sequence by converting the DNA sequence into a plurality of binary indicator sequences (BIS), and applying short term Fourier transform (STFT) on the binary indicator sequences. A binning function (BF) is applied to the Fourier coefficients (Usk_X(k)) and thereby modifying the corresponding Fourier coefficients (Usk_X(k)). Finally, substantially equal modified Fourier coefficients (Usk_X(k)) is found. The invention provides the user with a much improved ability to see unique strong patterns in vast amount of DNA sequence data.

摘要翻译： 本发明涉及DNA序列分析方法。 DNA序列通过将DNA序列转化为多个二进制指示符序列（BIS），并在二进制指示符序列上应用短期傅里叶变换（STFT）。 分数函数（BF）被应用于傅里叶系数（Usk_X（k）），从而修改对应的傅里叶系数（Usk_X（k））。 最后，找到基本相等的修正傅里叶系数（Usk_X（k））。 本发明为用户提供了大量改进的在大量DNA序列数据中看到独特强大模式的能力。

公开(公告)号：US20100008554A1

公开(公告)日：2010-01-14

申请号：US12516931

申请日：2007-12-03

申请人： Lalitha Agnihotri ,  James David Schaffer ,  Nevenka Dimitrova

发明人： Lalitha Agnihotri ,  James David Schaffer ,  Nevenka Dimitrova

IPC分类号： G06K9/00

CPC分类号： G06K9/00134 ,  G06K9/3233 ,  G06K9/3275 ,  G06T7/70 ,  G06T2207/20056 ,  G06T2207/30072

摘要： A method of automatically identifying the microarray chip corners and probes, even if there are no probes at the corners, in a high density and high resolution microarray scanned image having an image space, wherein the method minimizes the error distortions in the image arising in the scanning process by applying to the image a multipass corner finding algorithm comprising: (a) applying a Radon transform to an input microarray image to project the image into an angle and distance space where it is possible to find the orientation of the straight lines; (b) applying a fast Fourier transform to the projected image of (a) to find the optimal tilting angle of the projected image; (c) determining the optimal first and last local maxima for the optimal tilting angle; (d) back projecting the determined first and last local maxima to the image space to find the first approximation of the first and last column lines of the image; (e) rotating the image and repeating steps (a) through (d) to find the first approximation of the top and bottom row lines of the image; (f) determining the first approximation of the four corners of the image from the intersection of the column and row lines; (g) applying a heuristic for determining if the first approximation of step (f) is sufficient; and (h) optionally trimming the scanned image around the first approximation of the four corners and repeating steps (a) through (f).

摘要翻译： 即使在具有图像空间的高密度和高分辨率的微阵列扫描图像中，即使在角落处没有探针也能够自动识别微阵列芯片角部和探针的方法，其中该方法使图像中产生的图像中的误差失真最小化 扫描过程，通过向图像应用多点角发现算法，包括：（a）将Radon变换应用于输入微阵列图像以将图像投影到可以找到直线的取向的角度和距离空间中; （b）对（a）的投影图像应用快速傅立叶变换以找到投影图像的最佳倾斜角; （c）确定最佳倾斜角的最佳第一和最后局部极大值; （d）将确定的第一和最后局部最大值向前投影到图像空间，以找到图像的第一列和最后一列的第一近似; （e）旋转图像并重复步骤（a）至（d）以找到图像的顶行和下行行的第一近似值; （f）从列和行之间的交点确定图像的四个角的第一近似值; （g）应用启发式来确定步骤（f）的第一近似是否足够; 和（h）可选地修整围绕四个角的第一近似的扫描图像并重复步骤（a）至（f）。

公开(公告)号：US07599554B2

公开(公告)日：2009-10-06

申请号：US10552829

申请日：2004-04-02

申请人： Lalitha Agnihotri ,  Nevenka Dimitrova ,  John Kender

发明人： Lalitha Agnihotri ,  Nevenka Dimitrova ,  John Kender

IPC分类号： G06K9/34

CPC分类号： G06K9/00711 ,  G06F17/30793 ,  G06F17/30796 ,  G06F17/30843 ,  H04H60/58

摘要： A method and apparatus are provided for segmenting and summarizing a music video (507) in a multimedia stream (505) using content analysis. A music video (507) is segmented in a multimedia stream (505) by evaluating a plurality of content features that are related to the multimedia stream. The plurality of content features includes at least two of a face presence feature; a videotext presence feature; a color histogram feature; an audio feature, a camera cut feature; and an analysis of key words obtained from a transcript of the at least one music video. The plurality of content features are processed using a pattern recognition engine (1000), such as a Bayesian Belief Network, or one or more video segmentation rules (1115) to identify the music video (507) in the multimedia stream (505). A chorus is detected in at least one music video (507) using a transcript (T) of the music video (507) based upon a repetition of words in the transcript. The extracted chorus may be employed for the automatic generation of a summary of the music video (507).

摘要翻译： 提供了一种使用内容分析在多媒体流（505）中分割和汇总音乐视频（507）的方法和装置。 通过评估与多媒体流相关的多个内容特征，音乐视频（507）在多媒体流（505）中被分割。 多个内容特征包括面部存在特征中的至少两个; 录像带存在功能; 颜色直方图特征; 音频功能，相机切割功能; 以及从至少一个音乐视频的抄本获得的关键词的分析。 使用诸如贝叶斯信仰网络的模式识别引擎（1000）或者识别多媒体流（505）中的音乐视频（507）的一个或多个视频分段规则（1115）来处理多个内容特征。 基于抄本中的单词的重复，使用音乐视频（507）的抄本（T）在至少一个音乐视频（507）中检测到合唱。 提取的合唱可以用于自动生成音乐视频的摘要（507）。