公开(公告)号：US20140031922A1

公开(公告)日：2014-01-30

申请号：US13557488

申请日：2012-07-25

申请人： Niall Duffy ,  Ronan Rogers ,  John Gallagher ,  Gavin Kenny

发明人： Niall Duffy ,  Ronan Rogers ,  John Gallagher ,  Gavin Kenny

IPC分类号： A61F2/24

CPC分类号： A61F2/966 ,  A61F2/2436 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9665

摘要： Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly with a rotatable control knob and a catheter including an introducer shaft, an intermediate shaft extending from the handle assembly, an inner shaft extending from the handle assembly, and a capsule for containing a prosthesis. The distal end of the capsule can be connected to a distal end of the inner shaft, which can be moved in a distal direction by the rotatable control knob to deploy the prosthesis. By advancing the introducer through the deployed prosthesis and retracting the capsule to mate with the introducer, a smooth profile can be created for retraction of the system through the deployed prosthesis, minimizing hang-ups and snagging.

摘要翻译： 公开了使用输送导管递送和植入心脏瓣膜的心脏瓣膜输送系统和方法。 输送系统可以包括具有可旋转控制旋钮的手柄组件和包括导引器轴的导管，从手柄组件延伸的中间轴，从手柄组件延伸的内轴以及用于容纳假体的胶囊。 胶囊的远端可以连接到内轴的远端，其可以通过可旋转的控制旋钮在远端方向上移动以展开假体。 通过推进引导器穿过部署的假体并缩回胶囊以与导引器配合，可以创建平滑的轮廓，用于通过部署的假体缩回系统，最大限度地减少挂起和阻塞。

公开(公告)号：US20120158129A1

公开(公告)日：2012-06-21

申请号：US13325439

申请日：2011-12-14

申请人： Niall Duffy ,  Gerry McCaffrey ,  Noam Miller ,  Yossi Tuval ,  Daniel Glozman

发明人： Niall Duffy ,  Gerry McCaffrey ,  Noam Miller ,  Yossi Tuval ,  Daniel Glozman

IPC分类号： A61F2/24

CPC分类号： A61F2/2427 ,  A61F2/2436 ,  A61F2002/9505 ,  A61F2250/0032 ,  A61F2250/0097 ,  A61F2250/0098

摘要： A valve retainer is connected to an elongate delivery member. The valve retainer is configured to releasably secure a prosthesis (e.g., a heart valve prosthesis) to the delivery member during delivery to a target site in a body (e.g., a native valve annulus). The valve retainer includes a rotational identifier that identifies the rotational orientation of the valve retainer when the valve retainer is positioned proximate to the target site. A heart valve prosthesis can include a commissural post that has a predetermined rotational position relative to the rotational identifier, such that the heart valve prosthesis can be rotationally aligned with the native commissures of the native valve by rotating the delivery member and the valve retainer until the commissural post is aligned with a native valve commissure and the rotational identifier is visible.

摘要翻译： 阀保持器连接到细长的传送构件。 阀保持器被构造成在输送到身体（例如，天然瓣膜环）中的目标部位时将假体（例如，心脏瓣膜假体）可释放地固定到递送构件。 阀保持器包括旋转标识符，当旋转标识符识别当阀保持器靠近目标位置定位时的阀保持器的旋转取向。 心脏瓣膜假体可以包括相对于旋转标识符具有预定旋转位置的连合柱，使得心脏瓣膜假体可以通过旋转输送构件和阀保持器而旋转地对准天然瓣膜的天然连合，直到 连合柱与天然瓣膜吻合对齐，旋转识别符可见。

公开(公告)号：US20100130852A1

公开(公告)日：2010-05-27

申请号：US12275405

申请日：2008-11-21

申请人： Michael R. Neidert ,  Niall Duffy ,  Neil L. Purcell ,  Ronan Thornton

发明人： Michael R. Neidert ,  Niall Duffy ,  Neil L. Purcell ,  Ronan Thornton

IPC分类号： A61M25/092 ,  A61B5/055

CPC分类号： A61M25/0043 ,  A61M25/0045 ,  A61M25/005 ,  A61M2025/0024 ,  A61M2025/0025 ,  A61M2025/0681 ,  A61N1/056

摘要： A catheter system for positioning of a medical instrument that includes a first elongate member having a first lumen. The catheter system also includes a second elongate member that includes a second lumen that receives the medical instrument. The second elongate member is coupled directly to the first elongate member, and the second elongate member is operable to be at least partially segmented generally along a second longitudinal axis thereof to allow movement of the medical instrument outside the second lumen. The second elongate member is selectively collapsible and expandable to change a size of the second lumen.

摘要翻译： 一种用于定位医疗器械的导管系统，其包括具有第一腔的第一细长构件。 导管系统还包括第二细长构件，其包括接收医疗器械的第二腔。 第二细长构件直接连接到第一细长构件，并且第二细长构件可操作以沿其第二纵向轴线至少部分地分段，以允许医疗器械在第二内腔外移动。 第二细长构件选择性地可折叠和可膨胀以改变第二内腔的尺寸。

公开(公告)号：US20100030154A1

公开(公告)日：2010-02-04

申请号：US12182659

申请日：2008-07-30

申请人： Niall Duffy

发明人： Niall Duffy

IPC分类号： A61M25/01

CPC分类号： A61M25/0668 ,  A61M2025/0188 ,  A61M2025/0675

摘要： A catheter system for positioning an instrument within a body that includes a hub defining a lumen therethrough for passage of the instrument toward the body. The catheter system also includes an elongate tubular member defining a lumen therethrough. The lumen of the elongate tubular member is in communication with the lumen of the hub for further passage of the instrument toward the body. The system also includes a slitter member that is coupled to the hub. The slitter member is disposed to slit the elongate tubular member as the elongate tubular member moves relative to the hub.

摘要翻译： 一种用于将仪器定位在体内的导管系统，该导管系统包括限定通过其的腔的毂，用于使器械朝向身体通过。 导管系统还包括限定通过其中的腔的细长管状构件。 细长管状构件的内腔与毂的内腔连通，用于器械进一步通向身体。 该系统还包括联接到轮毂的分切构件。 分切构件设置成当细长管状构件相对于轮毂移动时切割细长管状构件。

公开(公告)号：US20090132019A1

公开(公告)日：2009-05-21

申请号：US11940515

申请日：2007-11-15

申请人： Niall Duffy ,  Ian Matheson

发明人： Niall Duffy ,  Ian Matheson

IPC分类号： A61F2/84 ,  A61F2/82

CPC分类号： A61F2/958 ,  A61F2/954 ,  A61F2/97 ,  A61F2002/065

摘要： A bifurcate stent delivery catheter is disclosed that includes a proximal shaft and two distal shaft branches having a bifurcated stent mounted thereon, wherein one or more conventional balloon catheters may be advanced within lumens of the bifurcate catheter to deploy the bifurcated stent. Since no balloons are mounted on the bifurcate catheter, the clinician may use any combination of balloon sizes for deploying various portions of the bifurcated stent and thus custom-select appropriate balloon sizes to best treat the bifurcation. Once a conventional balloon catheter is positioned within a distal shaft branch of the bifurcate stent delivery catheter, each of the distal shaft branches of the bifurcate catheter are constructed to split or otherwise expand in a controlled manner upon expansion of the balloon catheter in order to allow the bifurcated stent to be expanded or deployed.

摘要翻译： 公开了一种分叉支架输送导管，其包括近端轴和具有安装在其上的分叉支架的两个远端轴分支，其中一个或多个常规气囊导管可以在分叉导管的腔内前进，以展开分叉支架。 由于在分叉导管上没有安装气球，临床医生可以使用球囊尺寸的任何组合来展开分叉支架的各个部分，并且因此定制选择合适的气囊尺寸以最好地治疗分叉。 一旦常规气囊导管定位在分叉支架输送导管的远端轴分支内，则分叉导管的每个远端轴分支被构造成在气囊导管膨胀时以受控的方式分开或以其它方式膨胀，以便允许 分叉支架要扩大或部署。

公开(公告)号：US07276045B2

公开(公告)日：2007-10-02

申请号：US10718689

申请日：2003-11-24

申请人： Niall Duffy

发明人： Niall Duffy

IPC分类号： A61M29/00

CPC分类号： A61M25/0169 ,  A61M25/0172 ,  A61M2025/0183

摘要： The invention disclosed herein provides a catheter that acts as both a rapid-exchange (RX) catheter and a multi-exchange (MX) catheter. The catheter includes a proximal shaft, transition shaft, distal shaft, and catheter conversion shaft. Attached to the distalmost tip of the conversion shaft is a clip. The clip allows the conversion shaft to be detachably secured to the transition shaft while the catheter and a guidewire are both in situ. When the clip attaches to the transition shaft, a clip port in the clip aligns with an exchange joint in the transition shaft. In doing so, the catheter conversion shaft and a guide member act to allow the guidewire to be accessible through a guidewire exit of the guide member. The guide member is slidable along the catheter conversion shaft such that the catheter is usable as a MX catheter.

摘要翻译： 本文公开的本发明提供一种用作快速交换（RX）导管和多交换（MX）导管）的导管。 导管包括近轴，过渡轴，远侧轴和导管转换轴。 连接到转换轴的最远端的尖端是夹子。 夹具允许转换轴可拆卸地固定到过渡轴，同时导管和导丝都处于原位。 当夹子连接到转换轴时，夹子中的夹子与转换轴中的交换接头对齐。 在这样做时，导管转换轴和引导构件用于允许导丝通过引导构件的导丝出口而接近。 引导构件可沿着导管转换轴滑动，使得导管可用作MX导管。

公开(公告)号：US20050205446A1

公开(公告)日：2005-09-22

申请号：US10804990

申请日：2004-03-18

申请人： Niall Duffy ,  Eddie Coyle ,  Thomas Farrell

发明人： Niall Duffy ,  Eddie Coyle ,  Thomas Farrell

IPC分类号： A61M25/00 ,  B65D83/10

CPC分类号： A61M25/002

摘要： An assembly for packaging a catheter having a flexible distal shaft and a proximal fitting coupled thereto comprises a flexible tube capable of being coiled and having a proximal end. A tubular retainer having a passageway extending therethrough has a substantially oval proximal section and a substantially circular distal section, the distal section for fittingly receiving the proximal end of the flexible tube. A resilient member is coupled to a wall of the retainer and projects into the passageway for controllably impeding movement through the passageway.

摘要翻译： 一种用于包装导管的组件，其具有柔性远端轴和与其相连接的近侧配件，其包括能够卷绕并具有近端的柔性管。 具有延伸穿过其的通道的管状保持器具有基本上椭圆形的近端部分和基本上圆形的远端部分，该远端部分用于适配地容纳柔性管的近端。 弹性构件联接到保持器的壁并突出到通道中，用于可控制地阻碍通过通道的运动。

公开(公告)号：US06902057B2

公开(公告)日：2005-06-07

申请号：US10350894

申请日：2003-01-24

申请人： Niall Duffy

发明人： Niall Duffy

IPC分类号： A61M25/00 ,  B65D83/10

CPC分类号： A61M25/002

摘要： The present invention protects a catheter during shipment and storage. The device holds a portion of the catheter suspended such that the portion does not contact the device. When the suspended portion includes a stent treated with a therapeutic coating, the coating is protected from physical damage and from the risk that extended contact of the coating with packaging materials may result in the therapeutic agent migrating out of the coating and into the packaging materials or components of the packaging materials migrating into the therapeutic coating, both of which can occur if a therapeutic coating remains in contact with another material for an extended period of time. A catheter bearing an untreated stent, a balloon catheter, and other types of catheter would be similarly protected from physical or chemical damage.

摘要翻译： 本发明在运输和储存期间保护导管。 该装置保持导管的一部分悬挂，使得该部分不接触该装置。 当悬挂部分包括用治疗涂层处理的支架时，保护该涂层免受物理损伤，并且由于涂层与包装材料的延伸接触可能导致治疗剂从涂层迁移到包装材料或 包装材料的组分迁移到治疗性涂层中，如果治疗性涂层与另一种材料保持长时间接触，则这两者都可能发生。 携带未经治疗的支架，气囊导管和其它类型的导管的导管将被类似地保护免受物理或化学损伤。

公开(公告)号：US08475523B2

公开(公告)日：2013-07-02

申请号：US13016877

申请日：2011-01-28

申请人： Niall Duffy

发明人： Niall Duffy

IPC分类号： A61F2/24

CPC分类号： A61F2/966 ,  A61F2/2436 ,  A61F2002/9665

摘要： A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.

摘要翻译： 根据本发明的导管组件包括手柄组件，导引器护套和远侧末端组件。 远端尖端组件可以包括第一和第二保持套管以及开槽尖端，其具有定位在开槽尖端的近端处的非创伤性尖端护套。 手柄组件可以包括固定的主手柄和允许使用者控制导管的远侧末端组件的两个或更多个旋转手柄。 手柄组件上的每个控制旋钮通过允许各种输送轴的精确操纵来控制导管的远侧末端上的部件的一部分。 每个输送轴从手柄组件延伸到相对于导管远端的位置。

公开(公告)号：US20110208296A1

公开(公告)日：2011-08-25

申请号：US12911458

申请日：2010-10-25

申请人： Niall Duffy ,  Paul Mearns ,  John Gallagher ,  Noam Miller

发明人： Niall Duffy ,  Paul Mearns ,  John Gallagher ,  Noam Miller

IPC分类号： A61F2/24 ,  B23Q7/04

CPC分类号： A61F2/2427 ,  A61F2/95 ,  A61F2002/9522 ,  Y10T29/53996

摘要： Catheter assemblies including a handle assembly located on the proximal end of the catheter assembly and a distal tip assembly located on the distal end of the catheter assembly. A crimping funnel is slidably positioned along the catheter. The crimping funnel includes a distal end having a first diameter and a proximal end having a second diameter smaller than the first diameter. An axial split is formed in the proximal end. A first collar is provided encompassing a portion of the proximal end. The first collar is configured to hold the axial split in the proximal end together when the first collar is at a first axial location along the proximal end, and to allow the axial split in the proximal end to open when the first collar is at a second axial location along the proximal end, such that the crimping funnel can be removed from the catheter assembly. Various methods of retaining a prosthetic valve on the catheter assembly during the crimping process are described.

摘要翻译： 导管组件包括位于导管组件的近端上的把手组件和位于导管组件的远端上的远侧末端组件。 压接漏斗沿着导管可滑动地定位。 卷曲漏斗包括具有第一直径的远端和具有小于第一直径的第二直径的近端。 在近端形成轴向分裂。 提供包围近端的一部分的第一套环。 当第一颈圈沿着近端位于第一轴向位置时，第一颈圈被构造成将近端中的轴向分裂保持在一起，并且当第一颈圈在第二颈圈处于第二颈圈时允许近端中的轴向分裂打开 沿着近端的轴向位置，使得可以从导管组件移除压接漏斗。 描述了在压接过程期间将修复瓣膜保持在导管组件上的各种方法。