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    Microneedle Delivery Device and Methods of Using Same
    1.
    发明申请
    Microneedle Delivery Device and Methods of Using Same 审中-公开
    微胶囊输送装置及其使用方法

    公开(公告)号：US20110014181A1

    公开(公告)日：2011-01-20

    申请号：US12505939

    申请日：2009-07-20

    Applicant: RONAN THORNTON

    Inventor： RONAN THORNTON

    IPC: A61M5/00 ,  A61K31/366 ,  A61K33/00 ,  A61K39/395 ,  A61K31/7088 ,  A61K31/436 ,  A61K35/00

    CPC classification number: A61K45/06 ,  A61M25/0084 ,  A61M37/0015 ,  A61M2025/0093 ,  A61M2037/003

    Abstract: Described herein are microneedle bioactive agent delivery systems, associated apparatus and methods of using such. The microneedles described herein are deliverable using a needle or syringe apparatus that can interface with existing medical devices or the devices can be used as standalone systems. The systems deliver at least one bioactive agent to a tissue in need thereof, for example, the myocardium.

    Abstract translation: 本文描述的是微针生物活性剂递送系统，相关联的装置和使用其的方法。 本文所述的微针可以使用可以与现有医疗装置接合的针或注射器装置来递送，或者该装置可以用作独立系统。 系统将至少一种生物活性剂递送至需要其的组织，例如心肌。

    NAVIGATION ENABLED LEAD DELIVERY CATHETER
    3.
    发明申请
    NAVIGATION ENABLED LEAD DELIVERY CATHETER 审中-公开
    导航启用导线导管

    公开(公告)号：US20100130852A1

    公开(公告)日：2010-05-27

    申请号：US12275405

    申请日：2008-11-21

    Applicant: Michael R. Neidert ,  Niall Duffy ,  Neil L. Purcell ,  Ronan Thornton

    Inventor： Michael R. Neidert ,  Niall Duffy ,  Neil L. Purcell ,  Ronan Thornton

    IPC: A61M25/092 ,  A61B5/055

    CPC classification number: A61M25/0043 ,  A61M25/0045 ,  A61M25/005 ,  A61M2025/0024 ,  A61M2025/0025 ,  A61M2025/0681 ,  A61N1/056

    Abstract: A catheter system for positioning of a medical instrument that includes a first elongate member having a first lumen. The catheter system also includes a second elongate member that includes a second lumen that receives the medical instrument. The second elongate member is coupled directly to the first elongate member, and the second elongate member is operable to be at least partially segmented generally along a second longitudinal axis thereof to allow movement of the medical instrument outside the second lumen. The second elongate member is selectively collapsible and expandable to change a size of the second lumen.

    Abstract translation: 一种用于定位医疗器械的导管系统，其包括具有第一腔的第一细长构件。 导管系统还包括第二细长构件，其包括接收医疗器械的第二腔。 第二细长构件直接连接到第一细长构件，并且第二细长构件可操作以沿其第二纵向轴线至少部分地分段，以允许医疗器械在第二内腔外移动。 第二细长构件选择性地可折叠和可膨胀以改变第二内腔的尺寸。

    Stent with increased longitudinal flexibility and scaffolding
    4.
    发明授权
    Stent with increased longitudinal flexibility and scaffolding 有权
    支架具有增加的纵向弹性和脚手架

    公开(公告)号：US07060090B2

    公开(公告)日：2006-06-13

    申请号：US10685328

    申请日：2003-10-15

    Applicant: Ronan Thornton

    Inventor： Ronan Thornton

    IPC: A61F2/06

    CPC classification number: A61F2/91 ,  A61F2/915 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91583

    Abstract: The present invention relates to a stent manufactured from a thin-walled tube of surgical implant quality. The stent comprises a plurality of main circumferential rings, a plurality of longitudinal links and a plurality of intermediate circumferential rings. The main circumferential rings are longitudinally spaced apart along a longitudinal axis. Circumferential gaps are formed between adjacent main circumferential rings. The longitudinal links span the gaps and are attached to adjacent main circumferential rings. The intermediate circumferential rings fill in the circumferential gaps and are attached to the longitudinal links. The present invention thereby provides a stent with adequate radial strength to properly deploy, adequate scaffolding affect to properly support vessel walls and increased longitudinal flexibility to easily maneuver through tortuous vessels.

    Abstract translation: 本发明涉及由外科植入物质量的薄壁管制造的支架。 支架包括多个主圆周环，多个纵向连杆和多个中间圆周环。 主圆周环沿着纵向轴线纵向间隔开。 在相邻的主圆周环之间形成圆周间隙。 纵向连杆跨越间隙并连接到相邻的主圆周环上。 中间圆周环填充在周向间隙中并且附接到纵向连杆。 因此，本发明提供了具有足够径向强度的支架以适当地部署，足够的脚手架影响以适当地支撑血管壁并增加纵向灵活性以容易地通过曲折血管操纵。

    Stent with increased longitudinal flexibility and scaffolding
    8.
    发明申请
    Stent with increased longitudinal flexibility and scaffolding 有权
    支架具有增加的纵向弹性和脚手架

    公开(公告)号：US20050085899A1

    公开(公告)日：2005-04-21

    申请号：US10685328

    申请日：2003-10-15

    Applicant: Ronan Thornton

    Inventor： Ronan Thornton

    IPC: A61F2/06 ,  A61F2/90

    CPC classification number: A61F2/91 ,  A61F2/915 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91583

    Abstract: The present invention relates to a stent manufactured from a thin-walled tube of surgical implant quality. The stent comprises a plurality of main circumferential rings, a plurality of longitudinal links and a plurality of intermediate circumferential rings. The main circumferential rings are longitudinally spaced apart along a longitudinal axis. Circumferential gaps are formed between adjacent main circumferential rings. The longitudinal links span the gaps and are attached to adjacent main circumferential rings. The intermediate circumferential rings fill in the circumferential gaps and are attached to the longitudinal links. The present invention thereby provides a stent with adequate radial strength to properly deploy, adequate scaffolding affect to properly support vessel walls and increased longitudinal flexibility to easily maneuver through tortuous vessels.

    Abstract translation: 本发明涉及由外科植入物质量的薄壁管制造的支架。 支架包括多个主圆周环，多个纵向连杆和多个中间圆周环。 主圆周环沿着纵向轴线纵向间隔开。 在相邻的主圆周环之间形成圆周间隙。 纵向连杆跨越间隙并连接到相邻的主圆周环上。 中间圆周环填充在周向间隙中并且附接到纵向连杆。 因此，本发明提供了具有足够径向强度的支架以适当地部署，足够的脚手架影响以适当地支撑血管壁并增加纵向灵活性以容易地通过曲折血管操纵。

    Laminated drug-polymer coated stent with dipped and cured layers
    9.
    发明申请
    Laminated drug-polymer coated stent with dipped and cured layers 有权
    具有浸渍和固化层的层压药物聚合物涂层支架

    公开(公告)号：US20050070997A1

    公开(公告)日：2005-03-31

    申请号：US10674296

    申请日：2003-09-29

    Applicant: Ronan Thornton ,  Finbar Dolan

    Inventor： Ronan Thornton ,  Finbar Dolan

    IPC: A61L31/10 ,  A61L31/16 ,  B32B7/00 ,  A61F2/06

    CPC classification number: A61L31/16 ,  A61L31/10 ,  A61L2300/608 ,  A61L2420/02 ,  A61L2420/08 ,  Y10T428/31663 ,  C08L83/04 ,  C08L39/06 ,  C08L33/02

    Abstract: The present invention provides a method of applying a drug-polymer coating on a stent. A stent framework is dipped into a first polymeric solution including a first polymer, a first therapeutic agent, and a first solvent. The polymeric solution is dried and the first polymer is cured to form a thin drug-polymer layer on the stent framework. The steps of dipping the stent framework into the first polymeric solution, drying the first polymeric solution, and curing the first polymer are repeated until a target drug-polymer coating thickness is disposed on the stent framework. A drug-polymer coated stent including a stent framework and a laminated drug-polymer coated stent, a system for treating a vascular condition, and a method of treating a vascular condition are also disclosed.

    Abstract translation: 本发明提供了在支架上涂敷药物 - 聚合物涂层的方法。 将支架框架浸入包括第一聚合物，第一治疗剂和第一溶剂的第一聚合溶液中。 将聚合物溶液干燥，并将第一聚合物固化以在支架框架上形成薄的药物 - 聚合物层。 重复将支架框架浸入第一聚合物溶液，干燥第一聚合物溶液和固化第一聚合物的步骤，直到目标药物 - 聚合物涂层厚度设置在支架框架上。 还公开了一种药物聚合物涂覆的支架，其包括支架框架和层叠药物聚合物涂覆的支架，用于治疗血管病症的系统和治疗血管病症的方法。

    Laminated Drug-Polymer Coated Stent with Dipped and Cured Layers
    10.
    发明申请
    Laminated Drug-Polymer Coated Stent with Dipped and Cured Layers 有权
    具有浸渍和固化层的层压药物聚合物涂层支架

    公开(公告)号：US20100228342A1

    公开(公告)日：2010-09-09

    申请号：US12782286

    申请日：2010-05-18

    Applicant: Ronan Thornton ,  Finbar Dolan

    Inventor： Ronan Thornton ,  Finbar Dolan

    IPC: A61F2/82 ,  A61M25/00 ,  B05D1/18

    CPC classification number: A61L31/16 ,  A61L31/10 ,  A61L2300/608 ,  A61L2420/02 ,  A61L2420/08 ,  Y10T428/31663 ,  C08L83/04 ,  C08L39/06 ,  C08L33/02

    Abstract: The present invention provides a method of applying a drug-polymer coating on a stent. A stent framework is dipped into a first polymeric solution including a first polymer, a first therapeutic agent, and a first solvent. The polymeric solution is dried and the first polymer is cured to form a thin drug-polymer layer on the stent framework. The steps of dipping the stent framework into the first polymeric solution, drying the first polymeric solution, and curing the first polymer are repeated until a target drug-polymer coating thickness is disposed on the stent framework. A drug-polymer coated stent including a stent framework and a laminated drug-polymer coated stent, a system for treating a vascular condition, and a method of treating a vascular condition are also disclosed.

    Abstract translation: 本发明提供了在支架上涂敷药物 - 聚合物涂层的方法。 将支架框架浸入包括第一聚合物，第一治疗剂和第一溶剂的第一聚合溶液中。 将聚合物溶液干燥，并将第一聚合物固化以在支架框架上形成薄的药物 - 聚合物层。 重复将支架框架浸入第一聚合物溶液，干燥第一聚合物溶液和固化第一聚合物的步骤，直到目标药物 - 聚合物涂层厚度设置在支架框架上。 还公开了一种药物聚合物涂覆的支架，其包括支架框架和层叠药物聚合物涂覆的支架，用于治疗血管病症的系统和治疗血管病症的方法。

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