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公开(公告)号：US08630702B2
公开(公告)日：2014-01-14
申请号：US11594806
申请日：2006-11-09
申请人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson , Bruce Hopenfeld , Michael Sasha John
发明人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson , Bruce Hopenfeld , Michael Sasha John
IPC分类号： A61B5/0452
CPC分类号： A61B5/0456 , A61B5/0006 , A61B5/0031 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/7465 , A61B2560/0209 , A61N1/3627 , A61N1/3702
摘要： A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal and a patient alarm means is further provided and electrically coupled to the electrical signal processor. The electrical signal is acquired in the form of electrogram segments, which are categorized according to heart rate, ST segment shift and type heart rhythm (normal or abnormal). Baseline electrogram segments are tracked over time.
摘要翻译： 提供了一种用于检测在人类患者中发生的心脏事件的系统。 系统中包括至少两个电极，以从患者的心脏获得电信号。 电信号处理器电耦合到电极以处理电信号，并且还提供患者报警装置并电耦合到电信号处理器。 电信号是以心律，ST段移位和心律（正常或异常）分为心电图段的形式获得的。 基线电描绘片段随时间跟踪。
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公开(公告)号：US08157856B2
公开(公告)日：2012-04-17
申请号：US11804710
申请日：2007-05-18
IPC分类号： A61F2/82
CPC分类号： A61F2/844 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91533 , A61F2002/9155 , A61F2210/0019
摘要： A method for implanting a balloon expandable stent at a site within a passageway of a curved coronary article. The stent includes at least two longitudinally spaced apart circumferential rings. At least one longitudinally extending connector extends between adjacent rings. The connector has at least one turn back portion that can expand or contract in length while being passed through a curved passageway. The stent is disposed on a stent delivery catheter having an inflatable balloon. The stent delivery catheter and the stent is delivered through the passageway to the site of implementation with the connector member expanding or contracting in length to facilitate delivery and placement of the stent. The stent is expanded at the site of implantation by inflating the balloon to force the stent radially outward against the wall of the coronary artery.
摘要翻译： 一种用于将球囊可扩张支架植入弯曲冠状动脉制品通道内的部位的方法。 支架包括至少两个纵向间隔开的周向环。 至少一个纵向延伸的连接器在相邻的环之间延伸。 连接器具有至少一个回转部分，其能够在穿过弯曲通道的同时膨胀或收缩。 支架设置在具有可膨胀气囊的支架输送导管上。 支架输送导管和支架通过通道被输送到实现位置，连接器构件的长度膨胀或收缩以便于支架的输送和放置。 通过使气囊膨胀来使支架在植入部位扩张，以使支架径向向外抵靠冠状动脉壁。
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公开(公告)号：US20100222688A1
公开(公告)日：2010-09-02
申请号：US12457190
申请日：2009-06-03
申请人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson
发明人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson
IPC分类号： A61B5/0402 , G08B23/00
CPC分类号： A61B5/0452 , A61B5/0006 , A61B5/0031 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/7465 , A61B2560/0209 , A61N1/3627 , A61N1/3702
摘要： Disclosed is a system for the detection of cardiac events that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using different algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means) which are activated after the ST segment of the electrogram exceeds a preset threshold.
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44.发明授权Means and method for the accurate placement of a stent at the ostium of an artery 有权支架在动脉口的准确放置的方法和方法公开(公告)号：US07651520B2
公开(公告)日：2010-01-26
申请号：US11975196
申请日：2007-10-18
CPC分类号： A61F2/95 , A61F2002/821 , A61F2250/0098
摘要： Disclosed is an ostial stent positioner that has the form of a wire for most of its length and having a short cylinder with a longitudinal slit and expandable legs situated at the positioner's distal end. The slit cylinder with its attached wire acts as an introducer sheath to introduce a stent delivery system with a stent into the artery that is to be stented. A second aspect of the present invention is a method for accurately placing a stent at the ostium of an artery that would have an ostial stenosis. Examples of such arteries that have ostial stenoses are the right and left main coronary arteries, a saphenous vein graft as used in coronary bypass surgery and the renal arteries. Also disclosed are designs for the slit cylinder that provides a variable diameter so as to fit snugly within guiding catheters having different inside diameters.
摘要翻译： 公开了一种口腔支架定位器，其具有大部分长度的线的形式，并且具有短圆柱体，其具有位于定位器的远端处的纵向狭缝和可扩展腿。 具有连接线的狭缝圆柱体用作导引鞘，以将具有支架的支架输送系统引入到要被固定的动脉中。 本发明的第二方面是一种将支架精确地放置在具有口腔狭窄的动脉的口处的方法。 具有口腔狭窄的这种动脉的实例是右冠状动脉和左主动脉冠状动脉，用于冠状动脉旁路手术的隐静脉移植物和肾动脉。 还公开了用于狭缝筒的设计，其提供可变直径，以便紧密地配合在具有不同内径的引导导管内。
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公开(公告)号：US07252679B2
公开(公告)日：2007-08-07
申请号：US09950956
申请日：2001-09-13
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2002/91583 , A61F2250/006 , A61F2250/0098
摘要： The present invention uses sets of strut members where the most distal set of strut members is similar to that of most stents in that the plane of the distal set of strut members is perpendicular to the stent's longitudinal axis. The present invention has a multiplicity of circumferential sets of strut members, but only the distal set of strut members has its plane perpendicular to the stent's longitudinal axis. The more proximal sets of strut members are angulated, so that the plane of the most proximal set of strut members has a preset angle such as 30°, 45° or 60° relative to the stent's longitudinal axis. The stent could also be formed from or coated with a highly radiopaque material. Alternately, a radiopaque marker could be placed at the most proximal point of the angulated, side branch stent, for the stent has to be rotated by the clinician until the plane of the most proximal angulated set of strut members is situated to be approximately parallel to the plane of the ostium of the side branch. It is also envisioned to widen the diagonal sections of the most proximal circumferential set of strut members to increase their radiopacity as compared to the radiopacity of the more distal circumferential sets of strut members. This can assist the clinician who places the side branch stent to have it properly placed at the ostium of the side branch.
摘要翻译： 本发明使用一组支柱构件，其中最远端的支柱构件组与大多数支架的组件相似，因为远端组的支柱构件的平面垂直于支架的纵向轴线。 本发明具有多个圆周组的支柱构件，但是只有远侧的支柱构件组具有与支架的纵向轴线垂直的平面。 较近的支柱构件组是成角度的，使得最近近的支柱构件组的平面相对于支架的纵向轴线具有预设的角度，例如30°，45°或60°。 支架也可以由高度不透射线的材料形成或涂覆。 或者，不透射线的标记物可以放置在角度分布的支侧支架的最近点处，因为支架必须由临床医生旋转，直到最近端的角度组的支柱构件的平面位于大致平行于 侧枝口的平面。 还设想加宽最近端的圆周组的支柱构件的对角部分，以增加它们的不透射线性，与较远端圆周组的支柱构件的辐射不透性相比。 这可以帮助放置侧支支架的临床医生将其适当地放置在侧支的口处。
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公开(公告)号：US06706061B1
公开(公告)日：2004-03-16
申请号：US09718558
申请日：2000-11-22
IPC分类号： A61F206
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91541 , A61F2002/91558 , A61F2002/91575 , A61F2002/91583
摘要： Disclosed is an open cell stent that has adjacent sets of circumferential struts connected by means of highly flexible, undulating, connecting struts. To decrease outward flaring of the circumferential struts when the pre-deployed stent is advance through highly curved vessels, each unconnected strut of the sets of circumferential struts has a decreased longitudinal length as compared to the longitudinal length of the circumferential struts that are connected by the flexible connecting struts. To decrease the propensity for outward flaring of the end set of circumferential struts, the longitudinal length of the end set of circumferential struts is shorter than the longitudinal length of the interior set of circumferential struts. Enhanced features of the circumferential sets of strut members of the stent are also disclosed. Specifically, variable strut width for the curved sections and the diagonal sections of the circumferential sets of strut members can be employed to enhance the stents radial rigidity and to provide enhanced radiopacity of the end sets of strut members compared to the radiopacity of the interior sets of strut members.
摘要翻译： 公开了一种开放式细胞支架，其具有通过高度柔性，起伏的连接支柱连接的相邻的一组周向支柱。 当预先布置的支架通过高度弯曲的容器前进时，为了减小周向支柱的向外扩张，与沿周向支柱连接的周向支柱的纵向长度相比，这组圆周支柱的每个未连接的支柱具有减小的纵向长度 柔性连接支柱。 为了减小圆周支柱的端部组件向外扩张的倾向，圆周支柱的端部组件的纵向长度短于内部组件的周向支柱的纵向长度。 还公开了支架的圆周组支柱构件的增强特征。 具体地说，可以采用弯曲部分的可变支撑宽度和周向组支撑构件的对角部分来增强支架的径向刚度，并且提供支柱构件的端部组的增强的不透射线性， 支柱成员。
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公开(公告)号：US06375660B1
公开(公告)日：2002-04-23
申请号：US09444104
申请日：1999-11-22
IPC分类号： A61F1100
CPC分类号： A61F2/95 , A61M2025/0186 , A61M2025/1004
摘要： The present invention is a stent delivery system that uses a short section of a guide wire that is fixedly attached to a distal section of a balloon angioplasty catheter. By not having a guide wire that slides through the balloon of the balloon angioplasty catheter, the balloon on which the stent is mounted can have a reduced diameter. Therefore, the outside diameter of the undeployed stent mounted onto that balloon is also minimized. This provides a minimum profile, i.e., a minimum outside diameter, for the stent. A minimum profile at the distal section of the stent delivery system is highly advantageous for improving the percentage of cases that can be treated by direct stenting; i.e., without requiring pre-dilation of a stenosis.
摘要翻译： 本发明是一种支架输送系统，其使用固定地附接到球囊血管成形术导管的远端部分的导线的短部分。 通过不具有滑动通过球囊血管成形术导管的球囊的导丝，安装支架的气囊可以具有减小的直径。 因此，安装在该球囊上的未部署的支架的外径也被最小化。 这为支架提供了最小外形，即最小外径。 在支架输送系统的远端部分的最小轮廓对于改善可通过直接支架置入治疗的病例的百分比是非常有利的; 即不需要预扩张狭窄。
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公开(公告)号：US5976153A
公开(公告)日：1999-11-02
申请号：US40939
申请日：1998-03-18
CPC分类号： A61F2/958
摘要： The present invention is a stent delivery catheter system for placing a stent within a stenosis in a vessel of a human body. The stent delivery catheter system utilizes a slideable sheath with a thin-walled distal portion that is situated coaxially over a stent that is placed onto a balloon located at the distal portion of a balloon angioplasty catheter. The distal end of a central portion of the sheath has an interior shoulder which is capable of exerting a distally directed push force on the balloon angioplasty catheter at a point that is just proximal to the stent. This push force is then transferred through the non-deployed stent to a gradually tapered, highly flexible, lubricity coated distal tip of the balloon angioplasty catheter. The structure of a continuous outer surface extending backward from the distal tip and onto the distal section of the sheath, plus the lubricity coating of the outer surfaces of the distal tip and the sheath, plus the increased stent delivery catheter system pushability provided by the sheath and the stent itself makes it possible for the stent delivery catheter system to be pushed through even very tight stenoses.
摘要翻译： 本发明是用于将支架置于人体血管狭窄的支架输送导管系统中。 支架输送导管系统利用具有薄壁远侧部分的可滑动护套，所述远侧部分同轴地位于支架上，所述支架放置在位于球囊血管成形术导管的远端部分的球囊上。 鞘的中心部分的远端具有内肩部，其能够在刚好靠近支架的点处在球囊血管成形术导管上施加远端指向的推力。 然后将该推力通过未展开的支架转移到球囊血管成形术导管的逐渐变细，高度柔性，润滑的涂覆的远端。 连续的外表面从远端延伸到护套的远端部分上的结构以及远端尖端和护套的外表面的润滑性涂层加上由护套提供的增加的支架输送导管系统推进性 并且支架本身使支架输送导管系统能够通过甚至非常紧的狭窄被推动。
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公开(公告)号：US5879282A
公开(公告)日：1999-03-09
申请号：US786677
申请日：1997-01-21
CPC分类号： A61N5/1002 , A61N2005/1004
摘要： A balloon catheter for irradiation with or without dilatation of an arterial stenosis has an inflatable balloon and a generally cylindrical, thin-walled, elastic radioactive source both located coaxially at a distal section of the balloon catheter. The elastic radioactive source is moved radially outward as a result of injection of an inflation fluid into the inflatable balloon thus placing the radioactive source in close proximity to the wall of a vessel of the human body into which the balloon catheter has been inserted.
摘要翻译： 用于在有或没有动脉狭窄扩张的情况下照射的球囊导管具有可充气的球囊和大致圆柱形的薄壁弹性放射源，两者同轴地位于气囊导管的远端部分。 弹性放射源由于将充气流体注入到可膨胀气囊中而径向向外移动，从而将放射源放置在靠近人体容器的壁上，气球导管插入其中。
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50.发明授权
公开(公告)号：US5759174A
公开(公告)日：1998-06-02
申请号：US790447
申请日：1997-01-29
CPC分类号： A61F2/91 , A61F2/915 , A61F2/958 , A61B90/39 , A61F2002/91558 , A61F2230/0013 , A61F2250/0098 , A61M2025/1079 , A61M25/104
摘要： An expandable external radiopaque marker band is situated external to the balloon of a balloon angioplasty catheter typically at the balloon's longitudinal center. When the balloon is inflated to dilate an arterial stenosis, the external radiopaque marker band is moved radially outward by the balloon thereby forcing the external radiopaque marker band into the arterial wall. When the balloon is then deflated, the external radiopaque marker band remains in place against the wall of the dilated stenosis. The balloon angioplasty catheter can then be removed from the artery while the expanded external radiopaque marker band remains in place to indicate (typically) the center position of the dilated stenosis. The external radiopaque marker band is typically made from a dense, radiopaque metal such as tantalum, gold, platinum or an alloy of those dense metals.
摘要翻译： 可膨胀的外部不透射线标记带位于球囊血管成形术导管的气球的外部，通常位于气囊的纵向中心。 当气囊膨胀以扩张动脉狭窄时，外部不透射线的标记带通过气囊径向向外移动，从而迫使外部不透射线的标记带进入动脉壁。 当气囊然后放气时，外部不透射线的标记带保持在扩张狭窄的壁上的适当位置。 然后可以从动脉移除球囊血管成形术导管，而扩张的外部不透射线标记带保持在适当位置以指示（通常）扩张狭窄的中心位置。 外部不透射线标记带通常由致密的不透射线的金属如钽，金，铂或这些致密金属的合金制成。
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