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    Imaging system for cardiac planar imaging using a dedicated dual-head gamma camera
    42.
    发明授权
    Imaging system for cardiac planar imaging using a dedicated dual-head gamma camera 失效
    使用专用双头伽马相机的心脏平面成像成像系统

    公开(公告)号：US08017916B1

    公开(公告)日：2011-09-13

    申请号：US11824357

    申请日：2007-06-29

    申请人： Stanislaw Majewski ,  Marc M. Umeno

    发明人： Stanislaw Majewski ,  Marc M. Umeno

    IPC分类号： H01L27/146 ,  G01T1/20

    CPC分类号： G01T1/1648 ,  A61B6/4233 ,  A61B6/4241 ,  A61B6/4258 ,  A61B6/4266 ,  A61B6/503 ,  A61B6/5205

    摘要： A cardiac imaging system employing dual gamma imaging heads co-registered with one another to provide two dynamic simultaneous views of the heart sector of a patient torso. A first gamma imaging head is positioned in a first orientation with respect to the heart sector and a second gamma imaging head is positioned in a second orientation with respect to the heart sector. An adjustment arrangement is capable of adjusting the distance between the separate imaging heads and the angle between the heads. With the angle between the imaging heads set to 180 degrees and operating in a range of 140-159 keV and at a rate of up to 500kHz, the imaging heads are co-registered to produce simultaneous dynamic recording of two stereotactic views of the heart. The use of co-registered imaging heads maximizes the uniformity of detection sensitivity of blood flow in and around the heart over the whole heart volume and minimizes radiation absorption effects. A normalization/image fusion technique is implemented pixel-by-corresponding pixel to increase signal for any cardiac region viewed in two images obtained from the two opposed detector heads for the same time bin. The imaging system is capable of producing enhanced first pass studies, bloodpool studies including planar, gated and non-gated EKG studies, planar EKG perfusion studies, and planar hot spot imaging.

    摘要翻译： 使用双伽马成像头的心脏成像系统彼此共同登记以提供病人躯体的心脏部分的两个动态同时视图。 第一伽马成像头相对于心脏扇区被定位在第一方向，并且第二伽马成像头相对于心脏扇区定位在第二方位。 调节装置能够调节分离的成像头之间的距离和头部之间的角度。 由于成像头之间的角度设定为180度并且操作在140-159keV的范围内并且以高达500kHz的速率，成像头被共同配准以产生心脏的两个立体定向视图的同时动态记录。 使用共同注册的成像头使整个心脏体积中的心脏和其周围的血流的检测灵敏度的均匀性最大化并且最小化辐射吸收效应。 一个归一化/图像融合技术通过像素对应的像素来实现，以增加从用于相同时间块的两个相对的检测器头获得的两个图像中观察到的任何心脏区域的信号。 成像系统能够产生增强的一次通过研究，血液研究包括平面，门控和非门控EKG研究，平面EKG灌注研究和平面热点成像。

    High resolution PET breast imager with improved detection efficiency
    43.
    发明申请
    High resolution PET breast imager with improved detection efficiency 有权

    公开(公告)号：US20100074399A1

    公开(公告)日：2010-03-25

    申请号：US12284287

    申请日：2008-09-19

    申请人： Stanislaw Majewski

    发明人： Stanislaw Majewski

    IPC分类号： A61B6/04 ,  G01T1/164

    CPC分类号： G01T1/00 ,  A61B6/037 ,  G01T1/2008

    摘要： A highly efficient PET breast imager for detecting lesions in the entire breast including those located close to the patient's chest wall. The breast imager includes a ring of imaging modules surrounding the imaged breast. Each imaging module includes a slant imaging light guide inserted between a gamma radiation sensor and a photodetector. The slant light guide permits the gamma radiation sensors to be placed in close proximity to the skin of the chest wall thereby extending the sensitive region of the imager to the base of the breast. Several types of photodetectors are proposed for use in the detector modules, with compact silicon photomultipliers as the preferred choice, due to its high compactness. The geometry of the detector heads and the arrangement of the detector ring significantly reduce dead regions thereby improving detection efficiency for lesions located close to the chest wall.

    Anatomic and functional imaging of tagged molecules in animals
    44.
    发明授权
    Anatomic and functional imaging of tagged molecules in animals 失效
    动物中标记分子的解剖和功能成像

    公开(公告)号：US07209579B1

    公开(公告)日：2007-04-24

    申请号：US10341715

    申请日：2003-01-14

    申请人： Andrew G. Weisenberger ,  Stanislaw Majewski ,  Michael J. Paulus ,  Shaun S. Gleason

    发明人： Andrew G. Weisenberger ,  Stanislaw Majewski ,  Michael J. Paulus ,  Shaun S. Gleason

    IPC分类号： G06K9/00

    CPC分类号： A61B6/032 ,  A61B5/1077 ,  A61B5/1127 ,  A61B6/037 ,  A61B6/08 ,  A61B6/5235 ,  A61B6/5247 ,  A61B2503/40

    摘要： A novel functional imaging system for use in the imaging of unrestrained and non-anesthetized small animals or other subjects and a method for acquiring such images and further registering them with anatomical X-ray images previously or subsequently acquired. The apparatus comprises a combination of an IR laser profilometry system and gamma, PET and/or SPECT, imaging system, all mounted on a rotating gantry, that permits simultaneous acquisition of positional and orientational information and functional images of an unrestrained subject that are registered, i.e. integrated, using image processing software to produce a functional image of the subject without the use of restraints or anesthesia. The functional image thus obtained can be registered with a previously or subsequently obtained X-ray CT image of the subject. The use of the system described herein permits functional imaging of a subject in an unrestrained/non-anesthetized condition thereby reducing the stress on the subject and eliminating any potential interference with the functional testing that such stress might induce.

    摘要翻译： 用于无限制和非麻醉的小动物或其他受试者的成像中的新型功能成像系统以及用于获取这些图像并进一步将它们与先前或随后获得的解剖X射线图像对准的方法。 该装置包括IR激光轮廓测量系统和全部安装在旋转台架上的伽马，PET和/或SPECT成像系统的组合，其允许同时获取被登记的无限制对象的位置和定向信息和功能图像， 即集成的，使用图像处理软件来产生受试者的功能图像而不使用约束或麻醉。 这样获得的功能图像可以与先前或随后获得的受试者的X射线CT图像对齐。 本文描述的系统的使用允许受试者在无限制/非麻醉状态下进行功能成像，从而减少受试者的压力并消除对这种应激可能诱发的功能测试的任何潜在干扰。

    Dual energy scanning beam laminographic x-radiography
    46.
    发明授权
    Dual energy scanning beam laminographic x-radiography 失效
    双能量扫描光束层析x射线照相

    公开(公告)号：US5742660A

    公开(公告)日：1998-04-21

    申请号：US781722

    申请日：1997-01-10

    申请人： Stanislaw Majewski ,  Randolph F. Wojcik

    发明人： Stanislaw Majewski ,  Randolph F. Wojcik

    IPC分类号： A61B6/03 ,  H05G1/26 ,  H05G1/64

    CPC分类号： A61B6/032 ,  A61B6/4028 ,  A61B6/4241 ,  A61B6/482 ,  H05G1/26

    摘要： A multiple x-ray energy level imaging system includes a scanning x-ray beam and two detector design having a first low x-ray energy sensitive detector and a second high x-ray energy sensitive detector. The low x-ray energy detector is placed next to or in front of the high x-ray energy detector. The low energy sensitive detector has small stopping power for x-rays. The lower energy x-rays are absorbed and converted into electrical signals while the majority of the higher energy x-rays pass through undetected. The high energy sensitive detector has a large stopping power for x-rays as well as it having a filter placed between it and the object to absorb the lower energy x-rays. In a second embodiment; a single energy sensitive detector is provided which provides an output signal proportional to the amount of energy in each individual x-ray it absorbed. It can then have an electronic threshold or thresholds set to select two or more energy ranges for the images. By having multiple detectors located at different positions, a dual energy laminography system is possible.

    摘要翻译： 多个x射线能级成像系统包括扫描x射线束和具有第一低x射线能量敏感检测器和第二高x射线能量敏感检测器的两个检测器设计。 低X射线能量检测器放置在高X射线能量检测器旁边或前面。 低能量敏感检测器对于X射线具有较小的停止功率。 较低能量的X射线被吸收并转换为电信号，而大部分较高能量的X射线通过未被检测到。 高能量敏感检测器对于X射线具有大的阻挡力，并且其具有放置在其与物体之间的过滤器以吸收较低能量的X射线。 在第二实施例中; 提供单个能量敏感检测器，其提供与其吸收的每个单独X射线中的能量的量成比例的输出信号。 然后可以设置电子阈值或阈值来选择图像的两个或多个能量范围。 通过具有位于不同位置的多个检测器，双能量层析系统是可能的。