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    Dedicated mobile high resolution prostate PET imager with an insertable transrectal probe
    3.
    发明授权
    Dedicated mobile high resolution prostate PET imager with an insertable transrectal probe 有权
    专用移动高分辨率前列腺PET成像仪与可插入的经直肠探针

    公开(公告)号：US07858944B2

    公开(公告)日：2010-12-28

    申请号：US12321666

    申请日：2009-01-23

    申请人： Stanislaw Majewski ,  James Proffitt

    发明人： Stanislaw Majewski ,  James Proffitt

    IPC分类号： G01T1/164

    CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/425 ,  A61B6/4266 ,  A61B6/50 ,  A61B6/547 ,  G01T1/1603

    摘要： A dedicated mobile PET imaging system to image the prostate and surrounding organs. The imaging system includes an outside high resolution PET imager placed close to the patient's torso and an insertable and compact transrectal probe that is placed in close proximity to the prostate and operates in conjunction with the outside imager. The two detector systems are spatially co-registered to each other. The outside imager is mounted on an open rotating gantry to provide torso-wide 3D images of the prostate and surrounding tissue and organs. The insertable probe provides closer imaging, high sensitivity, and very high resolution predominately 2D view of the prostate and immediate surroundings. The probe is operated in conjunction with the outside imager and a fast data acquisition system to provide very high resolution reconstruction of the prostate and surrounding tissue and organs.

    摘要翻译： 专门的移动PET成像系统，用于对前列腺和周围器官进行成像。 成像系统包括放置在患者躯体附近的外部高分辨率PET成像器和放置在前列腺附近并与外部成像器结合操作的可插入和紧凑的经直肠探针。 两个检测器系统在空间上共同对齐。 外部成像仪安装在开放的旋转机架上，以提供前列腺和周围组织和器官的躯干宽的3D图像。 可插入的探针提供更接近的成像，高灵敏度和非常高的分辨率主要是前列腺和立即环境的2D视图。 探头与外部成像仪和快速数据采集系统一起运行，以提供前列腺和周围组织和器官的非常高分辨率的重建。

    Optical coupler
    4.
    发明授权
    Optical coupler 失效
    光耦合器

    公开(公告)号：US06750456B1

    公开(公告)日：2004-06-15

    申请号：US09577701

    申请日：2000-05-23

    申请人： Stanislaw Majewski ,  Andrew G. Weisenberger

    发明人： Stanislaw Majewski ,  Andrew G. Weisenberger

    IPC分类号： G01T120

    CPC分类号： G01T1/2002 ,  G01T1/1644

    摘要： In a camera or similar radiation sensitive device comprising a pixilated scintillation layer, a light guide and an array of position sensitive photomultiplier tubes, wherein there exists so-called dead space between adjacent photomultiplier tubes the improvement comprising a two part light guide comprising a first planar light spreading layer or portion having a first surface that addresses the scintillation layer and optically coupled thereto at a second surface that addresses the photomultiplier tubes, a second layer or portion comprising an array of trapezoidal light collectors defining gaps that span said dead space and are individually optically coupled to individual position sensitive photomultiplier tubes. According to a preferred embodiment, coupling of the trapezoidal light collectors to the position sensitive photomultiplier tubes is accomplished using an optical grease having about the same refractive index as the material of construction of the two part light guide.

    摘要翻译： 在包括像素化闪烁层，光导和位置敏感光电倍增管阵列的相机或类似的辐射敏感设备中，其中在相邻光电倍增管之间存在所谓的死空间，其改进包括两部分光导，包括第一平面 光扩散层或具有第一表面的部分，其处理闪烁层并在寻址光电倍增管的第二表面处光学耦合到其上;第二层或部分包括限定跨越所述死空间的间隙的梯形光收集器阵列，并且分别 光学耦合到单独的位置敏感光电倍增管。 根据优选实施例，使用具有与两部分光导的结构材料大致相同的折射率的光学润滑脂来实现梯形光收集器与位置敏感光电倍增管的耦合。

    Liquid-core light guide designed to withstand interior bubble formation from temperature-induced volumetric variations
    5.
    发明授权
    Liquid-core light guide designed to withstand interior bubble formation from temperature-induced volumetric variations 失效
    液芯导光器设计用于承受来自温度引起的体积变化的内部气泡形成

    公开(公告)号：US5859946A

    公开(公告)日：1999-01-12

    申请号：US885467

    申请日：1997-06-27

    申请人： Randolph Frank Wojcik ,  Stanislaw Majewski ,  Carl John Zorn

    发明人： Randolph Frank Wojcik ,  Stanislaw Majewski ,  Carl John Zorn

    IPC分类号： G02B6/032 ,  G02B6/20

    CPC分类号： G02B6/032

    摘要： A termination for a light guide having optical cladding tubing and a liquid core includes a volumetric change device configured to allow fluid flow out of the tubing whenever the liquid core expands and to allow fluid flow into the tubing whenever the liquid core contracts, an end plug fixed to the tubing to retain the liquid in the liquid core within the tubing and the end piece and a crimping piece for holding the end plug in place.

    摘要翻译： 用于具有光学包层管和液芯的光导体的端接件包括体积变化装置，其被配置成每当液芯膨胀时允许流体流出管道，并且每当液芯收缩时允许流体流入管道，端塞 固定到管道上以将液体保持在管芯和端部件内的液芯中，以及用于将端塞保持在适当位置的压接片。

    Radio frequency phototube
    8.
    发明授权
    Radio frequency phototube 失效
    射频光电管

    公开(公告)号：US08138460B1

    公开(公告)日：2012-03-20

    申请号：US12660966

    申请日：2010-03-08

    申请人： Amur Margaryan ,  Karlen Gynashyan ,  Osamu Hashimoto ,  Stanislaw Majewski ,  Linguang Tang ,  Gagik Marikyan ,  Lia Marikyan, legal representative

    发明人： Amur Margaryan ,  Karlen Gynashyan ,  Osamu Hashimoto ,  Stanislaw Majewski ,  Linguang Tang ,  Gagik Marikyan

    IPC分类号： H01J43/00 ,  H01J31/00 ,  H01J25/76

    CPC分类号： H01J31/50 ,  H01J31/506

    摘要： A method and apparatus of obtaining a record of repetitive optical or other phenomena having durations in the picosecond range, comprising a circular scan electron tube to receive light pulses and convert them to electron images consisting with fast nanosecond electronic signals, a continuous wave light or other particle pulses, e.g. electron picosecond pulses, and a synchronizing mechanism arranged to synchronize the deflection of the electron image (images) in the tube (tubes) with the repetition rate of the incident pulse train. There is also provided a method and apparatus for digitization of a repetitive and random optical waveform with a bandwidth higher than 10 GHz.

    摘要翻译： 一种获得具有皮秒范围持续时间的重复光学或其他现象的记录的方法和装置，包括用于接收光脉冲并将其转换成由快速纳秒电子信号组成的电子图像的圆形扫描电子管，连续波光或其它 粒子脉冲，例如 电子皮秒脉冲，以及同步机构，其将管（管）中的电子图像（图像）的偏转与入射脉冲序列的重复频率同步。 还提供了一种带宽高于10GHz的重复和随机光波形数字化的方法和装置。

    Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system
    10.
    发明授权
    Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system 有权
    在专用双头闪烁模拟系统中改善癌性病变检测灵敏度的方法

    公开(公告)号：US07444009B1

    公开(公告)日：2008-10-28

    申请号：US10961552

    申请日：2004-10-08

    申请人： Douglas Arthur Kieper ,  Stanislaw Majewski ,  Benjamin L. Welch

    发明人： Douglas Arthur Kieper ,  Stanislaw Majewski ,  Benjamin L. Welch

    IPC分类号： G06K9/00 ,  A61B6/04

    CPC分类号： A61B6/4258 ,  A61B6/502 ,  A61B6/583 ,  G01T1/1642 ,  G01T1/1644

    摘要： An improved method for enhancing the contrast between background and lesion areas of a breast undergoing dual-head scintimammographic examination comprising: 1) acquiring a pair of digital images from a pair of small FOV or mini gamma cameras compressing the breast under examination from opposing sides; 2) inverting one of the pair of images to align or co-register with the other of the images to obtain co-registered pixel values; 3) normalizing the pair of images pixel-by-pixel by dividing pixel values from each of the two acquired images and the co-registered image by the average count per pixel in the entire breast area of the corresponding detector; and 4) multiplying the number of counts in each pixel by the value obtained in step 3 to produce a normalization enhanced two dimensional contrast map. This enhanced (increased contrast) contrast map enhances the visibility of minor local increases (uptakes) of activity over the background and therefore improves lesion detection sensitivity, especially of small lesions.

    摘要翻译： 一种用于增强经历双头闪烁物理检查的乳房的背景和病变区域之间的对比度的改进方法，包括：1）从一对小的FOV或迷你伽马照相机获取一对数字图像，以从相对侧压缩检查的乳房; 2）反转一对图像中的一个以对准或共同对准另一个图像，以获得共同注册的像素值; 3）通过将两个获取的图像和共同注册的图像中的每一个的像素值除以相应检测器的整个乳房区域中的每个像素的平均计数来逐像素地归一化该对图像; 以及4）将每个像素中的计数数乘以步骤3中获得的值，以产生归一化增强二维对比图。 这种增强（增强的对比度）对比图增强了背景下活动的局部增加（摄取）的可见性，因此改善了病变检测灵敏度，特别是小病变的敏感性。