公开(公告)号：US06570954B2

公开(公告)日：2003-05-27

申请号：US10050252

申请日：2002-01-16

申请人： Volker Rasche ,  Erhard Paul Artur Klotz ,  Reiner Koppe

发明人： Volker Rasche ,  Erhard Paul Artur Klotz ,  Reiner Koppe

IPC分类号： H05G160

CPC分类号： A61B6/0457 ,  A61B6/032

摘要： An X-ray device for the formation of slice images of an object to be examined including an X-ray source, an X-ray detector, a transport device for moving the object during the acquisition of a series of X-ray projection images of the object in a movement plane situated parallel to the imaging plane, and a control device for controlling the acquisition of the X-ray projection images and the transport device. Slice images of the object are formed from the X-ray projection images by a tomosynthesis method. In order to enable the formation of slice images of large objects to be examined, or of large parts thereof, within a period of time which is as short as possible, the X-ray source and the X-ray detector are stationary during the acquisition of the X-ray projection images and the control device is configured such that the speed of motion of the object and the moments of acquisition of the X-ray projection images are such that all points to be examined in an examination zone of the object are imaged in at least 10, but preferably in at least 50 different X-ray projection images.

摘要翻译： 一种用于形成待检查对象的切片图像的X射线装置，包括X射线源，X射线检测器，用于在获取一系列X射线投影图像期间移动物体的输送装置 在与成像平面平行的运动平面中的物体，以及用于控制X射线投影图像和运送装置的获取的控制装置。 通过断层合成法从X射线投影图像形成物体的切片图像。 为了能够在尽可能短的时间内形成要检查的大对象或其大部分的切片图像，在采集期间X射线源和X射线检测器是静止的 的X射线投影图像和控制装置被配置为使得物体的运动速度和X射线投影图像的获取时刻使得在对象的检查区域中要检查的所有点是 在至少10个，但优选至少50个不同的X射线投影图像中成像。

公开(公告)号：US06473635B1

公开(公告)日：2002-10-29

申请号：US09675244

申请日：2000-09-29

申请人： Volker Rasche

发明人： Volker Rasche

IPC分类号： A61B505

CPC分类号： A61B5/06 ,  A61B5/062 ,  A61B5/7289

摘要： The invention relates to a method of and a device for determining the position of a medical instrument (4), introduced into the body of a patient (2), relative to a periodically moving organ (3) of the body, which method includes the steps of: a) determining the spatial position (c, r) of the medical instrument (4) and of a reference probe (6) while acquiring at the same time a periodic motion signal (E2) which relates to the periodic motion of the body organ (3), b) selecting a 3D image data set (p) from an image data base which contains 3D image data sets (p) of the body organ (3) which have been acquired pre-operatively and simultaneously with the same motion signal (E1) and are associated with individual motion phases (e1, e2, . . . ), in such a manner that that 3D image data set (p) is selected which is associated with the motion phase (e1, e2, . . . ) during the determination of the spatial position (c, r) of the medical instrument (4) and of the reference probe (6), and c) determining the position of the medical instrument (4) relative to the body organ (3) by converting the spatial position (6) of the medical instrument (4) by means of the positions of the reference probe which are known in space and in the selected 3D image data set.

摘要翻译： 本发明涉及一种用于确定相对于身体的周期性移动的器官（3）引入到患者体内的医疗器械（4）的位置的方法和装置，该方法包括 步骤：a）确定医疗器械（4）和参考探针（6）的空间位置（c，r），同时同时获取与周期性运动相关的周期运动信号（E2） 身体器官（3），b）从包含已经在手术前获取并同时获取的身体器官（3）的3D图像数据集（p）的图像数据库中选择3D图像数据集（p） 运动信号（E1）并且以与所述运动相位（e1，e2，...）相关联的所述3D图像数据集（p）的方式与各个运动相位（e1，e2，...）相关联。 在确定医疗器械（4）和参考探头（6）的空间位置（c，r）时，确定 通过在空间中已知的参考探针的位置转换医疗器械（4）的空间位置（6），相对于身体器官（3）的位置，相对于身体器官（3） 所选3D图像数据集。

公开(公告)号：US08446408B2

公开(公告)日：2013-05-21

申请号：US11997340

申请日：2006-07-12

申请人： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

发明人： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

IPC分类号： G06T15/00

CPC分类号： G06T11/005 ,  G06T2211/412

摘要： A method for generating or reconstruction of three-dimensional (3D) images corresponding to a structure of interest (60) including: acquiring a plurality of image projections corresponding to a structure of interest (60); applying a shape model (66) at a selected 3D seed point (64); and adapting the shape model (66) to represent the structure of interest (60), yielding an adapted shape model. A system for generation and reconstruction of three-dimensional (3D) images. The system (10) includes: an imaging system (12) configured to provide projection data corresponding to a structure of interest (60); and a controller (50) in operable communication with the imaging system (50). The controller (50) is configured to: receive the projection data, (64); apply a shape model (66) at a selected 3D seed point (64); and adapt the shape model (66) to represent the structure of interest (60), thereby yielding an adapted shape model.

摘要翻译： 一种用于生成或重建对应于感兴趣结构（60）的三维（3D）图像的方法，包括：获取与感兴趣结构相对应的多个图像投影（60）; 在选定的3D种子点（64）处应用形状模型（66）; 以及使形状模型（66）适应于表示感兴趣的结构（60），产生适应的形状模型。 一种用于三维（3D）图像的生成和重建的系统。 系统（10）包括：成像系统（12），被配置为提供对应于感兴趣结构（60）的投影数据; 以及与成像系统（50）可操作地通信的控制器（50）。 控制器（50）被配置为：接收投影数据（64）; 在选定的3D种子点（64）上应用形状模型（66）; 并适应形状模型（66）来表示感兴趣的结构（60），从而产生适应的形状模型。

公开(公告)号：US07660382B2

公开(公告)日：2010-02-09

申请号：US11570778

申请日：2005-06-24

申请人： Michael Grass ,  Volker Rasche

发明人： Michael Grass ,  Volker Rasche

IPC分类号： A61B6/00

CPC分类号： G06T11/005 ,  A61B6/027 ,  G06T2211/404 ,  G06T2211/412 ,  G06T2211/416

摘要： The invention relates to an examination apparatus and a method for perfusion studies in a patient (1). According to the method, a rotational X-ray device (10) is moved on a closed, preferably non-planar trajectory (T) while continuously generating projections of the patient (1) after the injection of a contrast agent with an injection device (20). The projections are used by a data processing system (30) in a sliding window technique to reconstruct three-dimensional images of the body volume. The resulting sequence of 3D images may be displayed on a monitor (31) to reveal the desired information about the perfusion process.

摘要翻译： 本发明涉及一种用于患者（1）中的灌注研究的检查装置和方法。 根据该方法，旋转X射线装置（10）在闭合的，优选非平面的轨迹（T）上移动，同时在用注射装置注射造影剂之后连续产生患者（1）的突起 20）。 数据处理系统（30）在滑动窗口技术中使用投影来重建身体体积的三维图像。 所得到的3D图像序列可以显示在监视器（31）上，以显示关于灌注过程的期望信息。

公开(公告)号：US07603159B2

公开(公告)日：2009-10-13

申请号：US10513011

申请日：2003-04-29

申请人： Volker Rasche

发明人： Volker Rasche

IPC分类号： A61B5/05

CPC分类号： A61B6/12

摘要： The invention relates to a method of determining the position of a catheter introduced along a guide wire inserted into a body, in which method an image of the guide wire and the body region at the area of the guide wire is acquired by means of an imaging method, the distance traveled by the catheter on the guide wire is measured and the position of the catheter in the body is determined on the basis of the measured distance. The invention also relates to a device for determining the position of a catheter introduced along a guide wire inserted into a body, which device includes sensor means for measuring the distance traveled by the catheter on the guide wire and means for determining the position of the catheter on the basis of the measured distance.

摘要翻译： 本发明涉及一种确定沿着插入人体内的导丝引入的导管的位置的方法，在该方法中，引导线的图像和导丝区域的身体区域通过成像获得 测量导管在导丝上行走的距离，并根据测得的距离确定导管在体内的位置。 本发明还涉及一种用于确定沿着插入到体内的导丝导入的导管的位置的装置，该装置包括用于测量导管在导丝上行进的距离的传感器装置，以及用于确定导管位置的装置 在测量距离的基础上。

公开(公告)号：US07529342B2

公开(公告)日：2009-05-05

申请号：US10567692

申请日：2004-08-03

申请人： Volker Rasche

发明人： Volker Rasche

IPC分类号： A61B6/00

CPC分类号： A61B6/541 ,  A61B5/0402 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/503 ,  A61B6/504

摘要： The invention relates to a device and a method for producing an image of the heart (5), in which the image is preferably three-dimensional and is reconstructed from a series of X-ray projection pictures from various projection directions. In this connection, the electrocardiogram (7) is recorded in parallel with the X-ray pictures and used by a data processing device (10) to control the picture-taking rate, the X-ray pulse duration, the tube current and/or the tube voltage of the X-ray device (1) in such a way that, during the phase to be displayed of maximum movement of the heart, the mean X-ray exposure rate is higher than during the other phases. The data processing device (10) may furthermore use the electrocardiogram to drive an injection pump (8) for the contrast agent in such a way that an approximately constant contrast display of the vessels is produced with minimum contrast-agent injection despite a variable flowrate in the vascular system.

摘要翻译： 本发明涉及一种用于制作心脏（5）的图像的装置和方法，其中图像优选地是三维的，并且是从各种投影方向的一系列X射线投影图像重建的。 在这方面，心电图（7）与X射线图像并行记录，并由数据处理装置（10）使用，以控制拍摄速度，X射线脉冲持续时间，管电流和/或 X射线装置（1）的管电压使得在要显示心脏的最大运动的相位期间，平均X射线曝光率高于其他阶段期间的平均X射线曝光率。 数据处理装置（10）还可以使用心电图来驱动造影剂的注射泵（8），使得以最小的造影剂注射产生容器的近似恒定的对比度显示，尽管可变流量在 血管系统。

公开(公告)号：US20080292149A1

公开(公告)日：2008-11-27

申请号：US11570629

申请日：2005-06-24

申请人： Volker Rasche

发明人： Volker Rasche

IPC分类号： G06K9/00

CPC分类号： G06T19/00 ,  A61B5/1075 ,  A61B6/03 ,  A61B6/12 ,  A61B6/466 ,  G06T2210/41 ,  G06T2219/028

摘要： The invention relates to an image processing system that is adapted to generate a three-dimensional image (32) from projections (P, 31) of a body volume which may for example be generated by a rotational X-ray system (10). The image processing system is further adapted to display on a monitor (30) simultaneously at least one of the original projections (31) and the generated 3D-image (32) together with a superimposed representation of a target region like an implantable stent. The user may then change the dimensions and the shape of the target region in any of the displayed images (31, 32) and watch the results in all images (31, 32). As the original projections (31) are free of errors generated by the reconstruction and visualization of the 3D-image (32), their consideration yields an improved geometrical accuracy.

摘要翻译： 本发明涉及一种适于从例如由旋转X射线系统（10）产生的体积的投影（P，31）产生三维图像（32）的图像处理系统。 图像处理系统还适于在监视器（30）上同时显示原始投影（31）和生成的3D图像（32）中的至少一个以及诸如可植入支架的目标区域的叠加表示。 然后，用户可以在任何所显示的图像（31,32）中改变目标区域的尺寸和形状，并观察所有图像（31,32）中的结果。 由于原始投影（31）没有由3D图像（32）的重建和可视化产生的错误，因此它们的考虑产生改进的几何精度。

公开(公告)号：US20060250386A1

公开(公告)日：2006-11-09

申请号：US10567221

申请日：2004-08-09

申请人： Babak Movassaghi ,  Volker Rasche

发明人： Babak Movassaghi ,  Volker Rasche

IPC分类号： G06T15/00

CPC分类号： G06K9/20 ,  G06K2009/00932 ,  G06K2209/05 ,  G06T7/55 ,  G06T2207/30101

摘要： The invention relates to a method for the reconstruction of a three-dimensional model of a vascular tree from two-dimensional X-ray projection images (A, B, C) that are taken from different spatial directions. On a first projection image (A) at least one reference point (CA) is specified. The gray-value profiles along the epipolar lines (EB, EC) for said reference point (CA) in other projection images (B, C) are then projected on the projection line (L) of the reference point (CA) and added there punctiformly to form a sum profile (S). The sum profile (S) has an extreme, for example, a gray-value minimum, at the position of the space point (C3D) belonging to the reference point (CA). In this way, it is possible to reconstruct semiautomatically a vascular tree from X-ray projections.

摘要翻译： 本发明涉及从不同空间方向拍摄的二维X射线投影图像（A，B，C）重建血管树的三维模型的方法。 在第一投影图像（A）上指定至少一个参考点（C SUB> A ）。 在其他投影图像中的用于所述参考点（C SUB）的沿着线极线（E SUB B，E C C）的灰度值分布（ B，C）然后投影在参考点（C SUB）上的投影线（L）上，并且以点一点的形式加到其中以形成总和曲线（S）。 总和简档（S）在属于参考点的空间点（C 3D 3D）的位置处具有例如灰度值最小值的极端（C A ）。 以这种方式，可以从X射线投影半自动重建血管树。

公开(公告)号：US20050171426A1

公开(公告)日：2005-08-04

申请号：US10513011

申请日：2003-04-29

申请人： Volker Rasche

发明人： Volker Rasche

IPC分类号： A61B6/00 ,  A61B6/12 ,  A61M25/01 ,  A61M25/095 ,  A61B5/05

CPC分类号： A61B6/12

摘要： The invention relates to a method of determining the position of a catheter introduced along a guide wire inserted into a body, in which method an image of the guide wire and the body region at the area of the guide wire is acquired by means of an imaging method, the distance traveled by the catheter on the guide wire is measured and the position of the catheter in the body is determined on the basis of the measured distance. The invention also relates to a device for determining the position of a catheter introduced along a guide wire inserted into a body, which device includes sensor means for measuring the distance traveled by the catheter on the guide wire and means for determining the position of the catheter on the basis of the measured distance.

摘要翻译： 本发明涉及一种确定沿着插入人体内的导丝引入的导管的位置的方法，在该方法中，引导线的图像和导丝区域的身体区域通过成像获得 测量导管在导丝上行走的距离，并根据测得的距离确定导管在体内的位置。 本发明还涉及一种用于确定沿着插入到体内的导丝导入的导管的位置的装置，该装置包括用于测量导管在导丝上行进的距离的传感器装置，以及用于确定导管位置的装置 在测量距离的基础上。

公开(公告)号：US06869217B2

公开(公告)日：2005-03-22

申请号：US09732200

申请日：2000-12-07

申请人： Volker Rasche ,  Hermann Schomberg ,  Erhard Paul Artur Klotz

发明人： Volker Rasche ,  Hermann Schomberg ,  Erhard Paul Artur Klotz

IPC分类号： B25J9/06 ,  A61B6/00 ,  A61B6/10 ,  H05G1/02

CPC分类号： A61B6/4441 ,  A61B6/4452 ,  A61B6/4458 ,  A61B6/4464

摘要： The invention relates to an X-ray device which includes an X-ray source and an X-ray detector which are mounted at a respective end of a common holding device. The holding device being attached to the room by way of a supporting device. In order to realize a more flexible construction of such X-ray devices that are widely used and are usually provided with a holding device in the form of a C-arm and nevertheless maintain a high positioning accuracy. The invention further relates to a supporting device constructed with a plurality of hinged, serially interconnected supporting members. The supporting device is formed notably by a serial manipulator, for example, a conventional robot arm.

摘要翻译： 本发明涉及一种X射线装置，其包括安装在公共保持装置的相应端部处的X射线源和X射线检测器。 保持装置通过支撑装置附接到房间。 为了实现广泛使用的这种X射线装置的更灵活的构造，并且通常设置有C形臂形式的保持装置，并且保持高的定位精度。 本发明还涉及一种由多个铰接的，串联连接的支撑构件构成的支撑装置。 支撑装置特别地由串联操纵器（例如常规的机器人手臂）形成。