公开(公告)号：US20100274009A1

公开(公告)日：2010-10-28

申请号：US12809665

申请日：2008-12-10

申请人： Petr Kubanek ,  Wolfgang Mägerlein ,  Ekkehard Schwab ,  Johann-Peter Melder ,  Manfred Julius

发明人： Petr Kubanek ,  Wolfgang Mägerlein ,  Ekkehard Schwab ,  Johann-Peter Melder ,  Manfred Julius

IPC分类号： C07D265/30 ,  C07D211/00 ,  C07C209/00 ,  B01J27/185 ,  B01J23/72

CPC分类号： B01J23/825 ,  B01J23/002 ,  B01J23/8474 ,  B01J23/888 ,  B01J37/03 ,  B01J37/18 ,  B01J2523/00 ,  C07C209/16 ,  C07C213/02 ,  C07C213/06 ,  C07D295/02 ,  C07D295/08 ,  B01J2523/17 ,  B01J2523/48 ,  B01J2523/51 ,  B01J2523/847 ,  B01J2523/69 ,  B01J2523/68 ,  B01J2523/32 ,  B01J2523/56 ,  C07C211/10 ,  C07C215/10 ,  C07C217/08 ,  C07C217/28

摘要： Processes for preparing an amine, the processes comprising: reacting a reactant selected from the group consisting of primary alcohols, secondary alcohols, aldehydes, ketones, and mixtures thereof, with hydrogen and a nitrogen compound selected from the group consisting of ammonia, primary amines, secondary amines and mixtures thereof, in the presence of a zirconium dioxide-, copper- and nickel-containing catalyst; wherein the catalyst comprises a catalytically active composition which comprises, before reduction with hydrogen, oxygen compounds of zirconium, copper, nickel, no oxygen compounds of cobalt, and 0.2 to 5.0% by weight of at least one oxygen compound of phosphorus or gallium, calculated as H3PO4 and Ga2O3 respectively.

摘要翻译： 用于制备胺的方法，所述方法包括：将选自伯醇，仲醇，醛，酮及其混合物的反应物与氢和选自以下的氮化合物反应：氨，伯胺， 仲胺及其混合物，在二氧化锆，含铜和镍的催化剂存在下; 其中所述催化剂包含催化活性组合物，其在用氢还原之前包括锆，铜，镍的氧化合物，不含钴的氧化合物和0.2至5.0重量％的至少一种磷或镓的氧化合物，计算 分别为H3PO4和Ga2O3。

公开(公告)号：US08017808B2

公开(公告)日：2011-09-13

申请号：US12293609

申请日：2007-03-13

申请人： Jan Eberhardt ,  Bram Willem Hoffer ,  Frank Haese ,  Johann-Peter Melder ,  Bernd Stein ,  Michael Stang ,  Thomas Hill ,  Ekkehard Schwab

发明人： Jan Eberhardt ,  Bram Willem Hoffer ,  Frank Haese ,  Johann-Peter Melder ,  Bernd Stein ,  Michael Stang ,  Thomas Hill ,  Ekkehard Schwab

IPC分类号： C07C209/16

CPC分类号： C07C209/26 ,  C07C2601/14 ,  C07D295/023 ,  C07C211/35 ,  C07C211/08

摘要： A process for preparing an amine by reacting an aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group of primary and secondary amines in the presence of a heterogeneous catalyst, wherein the catalyst is a coated catalyst which comprises at least one metal of group VIII of the Periodic Table of the Elements as a hydrogenating metal and additionally a promoter on an oxidic support, at least 80% of the metal of group VIII of the Periodic Table of the Elements being present in a layer between the surface of the catalyst and a penetration depth which is not more than 80% of the radius of the catalyst, calculated from the surface of the catalyst.

摘要翻译： 一种通过在多相催化剂存在下使醛和/或酮与氢和选自伯胺和仲胺的氮化合物反应制备胺的方法，其中催化剂是包含至少一种金属 作为氢化金属的元素周期表第Ⅷ族，另外是氧化载体上的助催化剂，元素周期表第VIII族金属的至少80％存在于 催化剂和渗透深度不超过催化剂半径的80％，由催化剂的表面计算。

公开(公告)号：US07683214B2

公开(公告)日：2010-03-23

申请号：US12282277

申请日：2007-03-01

申请人： Thilo Hahn ,  Frank Haese ,  Ulrich Köhler ,  Ekkehard Schwab ,  Johann-Peter Melder ,  Jan Eberhardt

发明人： Thilo Hahn ,  Frank Haese ,  Ulrich Köhler ,  Ekkehard Schwab ,  Johann-Peter Melder ,  Jan Eberhardt

IPC分类号： C07C249/02

CPC分类号： C07C249/02 ,  C07C251/16

摘要： A process for the preparation of benzophenonimine (BPI) of the general formula I where R1 and R2 are C1- to C4-alkoxy, C1- to C2-alkylamine and C2- to C4-dialkylamine and m and n are integers from 0 to 5 and R1 and R2, independently of one another, may be identical or different, by reacting benzophenone (BP) of the general formula II where R1, R2, m and n have the abovementioned meanings, in ammonia and in the presence of titanium dioxide, the titanium dioxide being present substantially in the anatase modification.

摘要翻译： 制备通式I的二苯甲酮亚胺（BPI）的方法，其中R 1和R 2是C 1 -C 4 - 烷氧基，C 1至C 2 - 烷基胺和C 2 -C 4 - 二烷基胺，m和n是0至5的整数 并且R 1和R 2可以相同或不同，通过使其中R1，R2，m和n具有上述含义的通式II的二苯甲酮（BP）在氨和二氧化钛存在下反应， 二氧化钛基本上存在锐钛矿改性。

公开(公告)号：US20090082562A1

公开(公告)日：2009-03-26

申请号：US12293609

申请日：2007-03-13

申请人： Jan Eberhardt ,  Bram Willem Hoffer ,  Frank Haese ,  Johann-Peter Melder ,  Bernd Stein ,  Michael Stang ,  Thomas Hill ,  Ekkehard Schwab

发明人： Jan Eberhardt ,  Bram Willem Hoffer ,  Frank Haese ,  Johann-Peter Melder ,  Bernd Stein ,  Michael Stang ,  Thomas Hill ,  Ekkehard Schwab

IPC分类号： C07D295/033

CPC分类号： C07C209/26 ,  C07C2601/14 ,  C07D295/023 ,  C07C211/35 ,  C07C211/08

摘要： A process for preparing an amine by reacting an aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group of primary and secondary amines in the presence of a heterogeneous catalyst, wherein the catalyst is a coated catalyst which comprises at least one metal of group VIII of the Periodic Table of the Elements as a hydrogenating metal and additionally a promoter on an oxidic support, at least 80% of the metal of group VIII of the Periodic Table of the Elements being present in a layer between the surface of the catalyst and a penetration depth which is not more than 80% of the radius of the catalyst, calculated from the surface of the catalyst.

摘要翻译： 一种通过在多相催化剂存在下使醛和/或酮与氢和选自伯胺和仲胺的氮化合物反应制备胺的方法，其中催化剂是包含至少一种金属 元素周期表第VIII族作为氢化金属，另外是氧化载体上的助催化剂，元素周期表第VIII族金属的至少80％存在于 催化剂和渗透深度不超过催化剂半径的80％，由催化剂的表面计算。

公开(公告)号：US20120071694A1

公开(公告)日：2012-03-22

申请号：US13274772

申请日：2011-10-17

申请人： JAN EBERHARDT ,  Thilo Hahn ,  Johann-Peter Melder ,  Gerhard Fritz ,  Volkmar Menger ,  Thomas Hill

发明人： JAN EBERHARDT ,  Thilo Hahn ,  Johann-Peter Melder ,  Gerhard Fritz ,  Volkmar Menger ,  Thomas Hill

IPC分类号： C07C209/48

CPC分类号： C07C253/30 ,  B01J8/025 ,  B01J2219/00103 ,  B01J2219/0011 ,  C07C209/48 ,  C07C211/11 ,  C07C255/24

摘要： A process for preparing a diamine from a corresponding aminoalkyl nitrile, which is prepared by reaction of a corresponding monoamine with a corresponding alkenyl nitrile in a continuous mode of operation, comprising the steps: a) introduction of the corresponding monoamine into a continuously conveyed reaction stream; b) introduction of the corresponding alkenyl nitrile into the reaction stream, with this already comprising the aminoalkyl nitrile on addition; c) reaction of the reaction stream in a first reaction region; d) at least partial transfer of the reaction stream into at least one second reaction region for further reaction; e) discharge of the reaction stream from the second reaction region after the reaction; f) introduction of the reaction stream discharged in step (a) into a reduction region; and g) reduction of the aminoalkyl nitrile present in the reaction stream to the corresponding diamine.

摘要翻译： 一种由相应的氨基烷基腈制备二胺的方法，该方法是通过相应的单胺与相应的链烯基腈在连续运行方式下反应而制得的，其中包括步骤：a）将相应的单胺引入连续输送的反应流 ; b）将相应的烯基腈引入反应流中，其中已加入氨基烷基腈; c）反应流在第一反应区域中的反应; d）将反应物流至少部分转移至至少一个第二反应区域用于进一步反应; e）反应后从第二反应区排出反应物流; f）将步骤（a）中排出的反应流引入还原区; 和g）将反应流中存在的氨基烷基腈还原成相应的二胺。

公开(公告)号：US20100267948A1

公开(公告)日：2010-10-21

申请号：US12301811

申请日：2007-05-24

申请人： Jan Eberhardt ,  Harald Meissner ,  Bram Willem Hoffer ,  Johann-Peter Melder ,  Ekkehard Schwab

发明人： Jan Eberhardt ,  Harald Meissner ,  Bram Willem Hoffer ,  Johann-Peter Melder ,  Ekkehard Schwab

IPC分类号： C07D265/30 ,  C07C209/02

CPC分类号： C07C209/26 ,  C07C2601/14 ,  C07D295/023 ,  C07C211/07 ,  C07C211/08 ,  C07C211/35

摘要： Process for preparing an amine by reacting an aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group consisting of primary and secondary amines in the presence of a heterogeneous catalyst, wherein the reaction is carried out using a suspended catalyst as heterogeneous catalyst and is carried out in the semibatch mode in which the nitrogen compound as one reactant is placed in the reaction vessel and the aldehyde and/or the ketone as the other reactant is added during the course of the reaction and the aldehyde and/or the ketone is added in portions or continuously to the reaction mixture during the course of the reaction as a function of the achieved conversion of the nitrogen compound until a conversion of the nitrogen compound of at least 95% results, and all or part of the catalyst remains in the reaction vessel after the reaction batch and is reused for the next reaction batch.

摘要翻译： 在非均相催化剂存在下使醛和/或酮与氢和选自伯胺和仲胺的氮化合物反应制备胺的方法，其中反应使用悬浮催化剂作为非均相催化剂进行 并且以半反应模式进行，其中作为一种反应物的氮化合物被放置在反应容器中，并且在反应过程中加入作为其它反应物的醛和/或酮，醛和/或酮 在反应过程中以部分或连续的方式加入到反应混合物中，作为实现氮化合物转化的函数，直至氮化合物的转化率至少为95％，并且全部或部分催化剂保持在 反应容器在反应批次后再次用于下一反应批次。

公开(公告)号：US20090093654A1

公开(公告)日：2009-04-09

申请号：US12282277

申请日：2007-03-01

申请人： Thilo Hahn ,  Frank Haese ,  Ulrich Koehler ,  Ekkehard Schwab ,  Johann-Peter Melder ,  Jan Eberhardt

发明人： Thilo Hahn ,  Frank Haese ,  Ulrich Koehler ,  Ekkehard Schwab ,  Johann-Peter Melder ,  Jan Eberhardt

IPC分类号： C07C251/24

CPC分类号： C07C249/02 ,  C07C251/16

摘要： A process for the preparation of benzophenonimine (BPI) of the general formula I where R1 and R2 are C1- to C4-alkoxy, C1- to C2-alkylamine and C2- to C4-dialkylamine and m and n are integers from 0 to 5 and R1 and R2, independently of one another, may be identical or different, by reacting benzophenone (BP) of the general formula II where R1, R2, m and n have the abovementioned meanings, in ammonia and in the presence of titanium dioxide, the titanium dioxide being present substantially in the anatase modification.

摘要翻译： 制备通式I的二苯甲酮亚胺（BPI）的方法，其中R 1和R 2是C 1 -C 4 - 烷氧基，C 1至C 2 - 烷基胺和C 2 -C 4 - 二烷基胺，m和n是0至5的整数 并且R 1和R 2可以相同或不同，通过使其中R1，R2，m和n具有上述含义的通式II的二苯甲酮（BP）在氨和二氧化钛存在下反应， 二氧化钛基本上存在锐钛矿改性。

公开(公告)号：US20080200727A1

公开(公告)日：2008-08-21

申请号：US11912981

申请日：2006-04-26

申请人： Jan Eberhardt ,  Bram Willem Hoffer ,  Ekkehard Schwab ,  Johann-Peter Melder ,  Udo Rheude

发明人： Jan Eberhardt ,  Bram Willem Hoffer ,  Ekkehard Schwab ,  Johann-Peter Melder ,  Udo Rheude

IPC分类号： C07C209/00

CPC分类号： C07D295/023 ,  C07C209/26 ,  C07C2601/14 ,  C07C211/35

摘要： Processes for preparing amines comprising reacting an aldehyde and/or ketone with hydrogen and a nitrogen compound in the presence of a heterogeneous catalyst, wherein the heterogeneous catalyst comprises a catalyst packing prepared by applying at least one compound selected from the group consisting of catalytically active metals, compounds of catalytically active metals, and mixtures thereof to a support material selected from the group consisting of woven fabrics, knitted fabrics, foils, and combinations thereof.

摘要翻译： 制备胺的方法，包括在非均相催化剂存在下使醛和/或酮与氢和氮化合物反应，其中非均相催化剂包括通过将至少一种选自催化活性金属的化合物 ，催化活性金属的化合物及其混合物与选自机织织物，针织物，箔及其组合的支撑材料组合。

公开(公告)号：US08497399B2

公开(公告)日：2013-07-30

申请号：US13274772

申请日：2011-10-17

申请人： Jan Eberhardt ,  Thilo Hahn ,  Johann-Peter Melder ,  Gerhard Fritz ,  Volkmar Menger ,  Thomas Hill

发明人： Jan Eberhardt ,  Thilo Hahn ,  Johann-Peter Melder ,  Gerhard Fritz ,  Volkmar Menger ,  Thomas Hill

IPC分类号： C07C209/48

CPC分类号： C07C253/30 ,  B01J8/025 ,  B01J2219/00103 ,  B01J2219/0011 ,  C07C209/48 ,  C07C211/11 ,  C07C255/24

摘要： A process for preparing a diamine from a corresponding aminoalkyl nitrile, which is prepared by reaction of a corresponding monoamine with a corresponding alkenyl nitrile in a continuous mode of operation, comprising the steps: a) introduction of the corresponding monoamine into a continuously conveyed reaction stream; b) introduction of the corresponding alkenyl nitrile into the reaction stream, with this already comprising the aminoalkyl nitrile on addition; c) reaction of the reaction stream in a first reaction region; d) at least partial transfer of the reaction stream into at least one second reaction region for further reaction; e) discharge of the reaction stream from the second reaction region after the reaction; f) introduction of the reaction stream discharged in step (a) into a reduction region; and g) reduction of the aminoalkyl nitrile present in the reaction stream to the corresponding diamine.

摘要翻译： 一种由相应的氨基烷基腈制备二胺的方法，该方法是通过相应的单胺与相应的链烯基腈在连续运行方式下反应而制得的，其中包括步骤：a）将相应的单胺引入连续输送的反应流 ; b）将相应的烯基腈引入反应流中，其中已加入氨基烷基腈; c）反应流在第一反应区域中的反应; d）将反应物流至少部分转移至至少一个第二反应区域用于进一步反应; e）反应后从第二反应区排出反应物流; f）将步骤（a）中排出的反应流引入还原区; 和g）将反应流中存在的氨基烷基腈还原成相应的二胺。

公开(公告)号：US08063239B2

公开(公告)日：2011-11-22

申请号：US12298939

申请日：2007-05-07

申请人： Jan Eberhardt ,  Thilo Hahn ,  Johann-Peter Melder ,  Gerhard Fritz ,  Volkmar Menger ,  Thomas Hill

发明人： Jan Eberhardt ,  Thilo Hahn ,  Johann-Peter Melder ,  Gerhard Fritz ,  Volkmar Menger ,  Thomas Hill

IPC分类号： C07F7/00

CPC分类号： C07C253/30 ,  B01J8/025 ,  B01J2219/00103 ,  B01J2219/0011 ,  C07C209/48 ,  C07C211/11 ,  C07C255/24

摘要： The present invention relates to a process for preparing an aminoalkyl nitrile by reaction of a corresponding monoamine with a corresponding alkenyl nitrile in a continuous mode of operation, which comprises the steps (a) introduction of the corresponding monoamine into a continuously conveyed reaction stream; (b) introduction of the corresponding alkenyl nitrite into the reaction stream, with this already comprising the aminoalkyl nitrile on addition; (c) reaction of the reaction stream in a first reaction region; and (d) at least partial transfer of the reaction stream into at least one second reaction region for further reaction. The invention further relates to a process for preparing a diamine from the aminoalkyl nitrile, suitable apparatuses for carrying out the processes and their corresponding use.

摘要翻译： 本发明涉及通过相应的单胺与相应的烯基腈在连续操作模式下反应来制备氨基烷基腈的方法，其包括步骤（a）将相应的单胺引入连续输送的反应流中; （b）将相应的烯基亚硝酸酯引入反应流中，其中已加入氨基烷基腈; （c）反应流在第一反应区域中的反应; 和（d）将反应物流至少部分转移到至少一个第二反应区域中用于进一步反应。 本发明还涉及从氨基烷基腈制备二胺的方法，用于实施该方法及其相应用途的合适装置。