CRF receptor antagonists and methods relating thereto
    42.
    发明授权
    CRF receptor antagonists and methods relating thereto 有权
    CRF受体拮抗剂及其相关方法

    公开(公告)号:US06723721B2

    公开(公告)日:2004-04-20

    申请号:US10027789

    申请日:2001-12-20

    IPC分类号: A61K31495

    CPC分类号: C07D471/16 C07D487/16

    摘要: Compounds are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, including stroke. The compounds of this invention have the following structures: wherein n, m, R, R1, R2, X and Ar are as defined herein, including stereoisomes and pharmaceutically acceptable salts thereof.

    摘要翻译: 公开了可用于治疗多种疾病的化合物,包括治疗在温血动物(包括中风)中表现出CRF过度分泌的病症。 本发明的化合物具有以下结构:其中n,m,R,R 1,R 2,X和Ar如本文所定义,包括立体异构体及其药学上可接受的盐。

    CRF receptor antagonists and methods relating thereto
    43.
    发明授权
    CRF receptor antagonists and methods relating thereto 失效
    CRF受体拮抗剂及其相关方法

    公开(公告)号:US06348466B1

    公开(公告)日:2002-02-19

    申请号:US09439841

    申请日:1999-11-12

    IPC分类号: A61K31495

    CPC分类号: C07D471/16 C07D487/16

    摘要: Compounds are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, including stroke. The compounds of this invention have the following structures: wherein n, m, R, R1, R2, X and Ar are as defined herein, including stereoisomes and pharmaceutically acceptable salts thereof.

    摘要翻译: 公开了可用于治疗多种疾病的化合物,包括治疗在温血动物(包括中风)中表现出CRF过度分泌的病症。 本发明的化合物具有以下结构:其中n,m,R,R 1,R 2,X和Ar如本文所定义,包括立体异构体及其药学上可接受的盐。