Optical fiber surface enhanced raman spectroscopy (SERS) probe
    52.
    发明授权
    Optical fiber surface enhanced raman spectroscopy (SERS) probe 有权
    光纤表面增强拉曼光谱(SERS)探针

    公开(公告)号:US09001324B2

    公开(公告)日:2015-04-07

    申请号:US13810982

    申请日:2010-07-30

    申请人: Zhiyong Li Min Hu Wei Wu

    发明人: Zhiyong Li Min Hu Wei Wu

    IPC分类号: G01J3/44 G01N21/65

    CPC分类号: G01N21/658

    摘要: A surface enhanced Raman spectroscopy (SERS) probe apparatus and a method of SERS probing employ Raman-active surfaces of a plurality of nanoscale field concentrator (NFC) structures at a terminal end of an optical fiber. The SERS probe apparatus includes an optical fiber having an optical path and a terminal end that terminates the optical path. The SERS probe apparatus further includes a plurality of NFC structures and nanoparticles on surfaces of the plurality of NFC structures. First ends of the NFC structures are adjacent to the terminal end of optical fiber. The nanoparticles are Raman active to an analyte.

    摘要翻译: 表面增强拉曼光谱(SERS)探针装置和SERS探测的方法在光纤的末端使用多个纳米尺度场集中器(NFC)结构的拉曼活性表面。 SERS探针装置包括具有光路的光纤和终止光路的终端。 SERS探针装置还包括在多个NFC结构的表面上的多个NFC结构和纳米颗粒。 NFC结构的第一端与光纤的终端相邻。 纳米颗粒是对分析物有活性的拉曼。

    DOUBLE-GRATING SURFACE-ENHANCED RAMAN SPECTROSCOPY
    54.
    发明申请
    DOUBLE-GRATING SURFACE-ENHANCED RAMAN SPECTROSCOPY 有权
    双光泽表面增强拉曼光谱

    公开(公告)号:US20140375990A1

    公开(公告)日:2014-12-25

    申请号:US14381009

    申请日:2012-03-06

    IPC分类号: G01J3/02 G01J3/44 G01N21/65

    摘要: A double-grating surface-enhanced Raman spectrometer. The spectrometer includes a substrate; a plurality of nanofingers carried by the substrate, the nanofingers arranged to define a first optical grating; a light source oriented to project a beam of light toward the first optical grating; a second optical grating oriented to receive a beam of light scattered from the first optical grating; and a detector oriented to receive a beam of light scattered from the second optical grating.

    摘要翻译: 双光栅表面增强拉曼光谱仪。 光谱仪包括基片; 由衬底承载的多个纳米装置,所述纳米装置布置成限定第一光栅; 光源,其朝向所述第一光栅投影光束; 第二光栅,其被定向为接收从第一光栅散射的光束; 以及用于接收从第二光栅散射的光束的检测器。

    APPARATUS FOR USE IN SENSING APPLICATIONS
    56.
    发明申请
    APPARATUS FOR USE IN SENSING APPLICATIONS 有权
    用于感应应用的装置

    公开(公告)号:US20140009758A1

    公开(公告)日:2014-01-09

    申请号:US14006436

    申请日:2011-03-24

    IPC分类号: G01N21/65 B05D3/00

    摘要: An apparatus for use in sensing applications includes a substrate and a plurality of clusters arranged in an aperiodic configuration on the substrate, wherein each of the plurality of clusters is formed of a plurality of Raman-active material nano-particles, and wherein each of the Raman-active material nano-particles is positioned in a substantially ordered configuration with respect to each other in each of the respective plurality of clusters.

    摘要翻译: 用于感测应用的装置包括基板和在基板上以非周期配置布置的多个簇,其中多个簇中的每一个由多个拉曼活性材料纳米颗粒形成,并且其中 拉曼活性材料纳米颗粒在相应的多个簇中的每一个中相对于彼此定位成基本排列的构型。

    SURFACE ENHANCED RAMAN SPECTROSCOPY CALIBRATION CURVE GENERATING SYSTEMS
    57.
    发明申请
    SURFACE ENHANCED RAMAN SPECTROSCOPY CALIBRATION CURVE GENERATING SYSTEMS 有权
    表面增强拉曼光谱校准曲线生成系统

    公开(公告)号:US20130278928A1

    公开(公告)日:2013-10-24

    申请号:US13449612

    申请日:2012-04-18

    IPC分类号: G01J3/44

    摘要: A surface enhanced Raman spectroscopy calibration curve generating system includes a SERS sensor, which includes a substrate and a plurality of sensing members formed on the substrate. Each of the sensing members includes a plurality of SERS signal amplifying structures. An inkjet dispensing device is to dispense different concentrations of a solution including a known analyte of interest onto the respective sensing members to form a concentration dependent array. A Raman spectrometer is to interrogate the concentration dependent array. A processor is operatively connected to each of the inkjet dispensing device and the Raman spectrometer. Computer-readable instructions are embedded on a non-transitory, tangible computer-readable medium and are executable by the processor. The computer-readable instructions are to automatically generate an intensity profile as a function of concentration for the concentration dependent array.

    摘要翻译: 表面增强拉曼光谱校准曲线生成系统包括SERS传感器,其包括衬底和形成在衬底上的多个感测构件。 每个感测构件包括多个SERS信号放大结构。 喷墨分配装置是将不同浓度的包括已知分析物的溶液分配到相应的感测构件上以形成浓度依赖阵列。 拉曼光谱仪是询问浓度依赖阵列。 处理器可操作地连接到每个喷墨分配装置和拉曼光谱仪。 计算机可读指令嵌入在非暂时有形的计算机可读介质中,并且可由处理器执行。 计算机可读指令是自动生成作为浓度依赖阵列的浓度的函数的强度分布。

    Computer-implemented systems and methods for efficiently selecting data in multi-dimensional hierarchical space with multiple constraints
    58.
    发明授权
    Computer-implemented systems and methods for efficiently selecting data in multi-dimensional hierarchical space with multiple constraints 有权
    计算机实现的系统和方法,用于在具有多个约束的多维分层空间中有效地选择数据

    公开(公告)号:US08549027B2

    公开(公告)日:2013-10-01

    申请号:US12487134

    申请日:2009-06-18

    IPC分类号: G06F7/00

    CPC分类号: G06F3/0481

    摘要: Computer-implemented systems and methods are provided for reducing a number of options presented to a user where the options have characteristics that are arranged in a multi-dimensional hierarchical space. A system and method can be configured to identify common dimensions using dimension nodes in dimensional points and identify compatible nodes for each dimension in the multi-dimensional hierarchical space by determining whether an association exists. Compatible pairs of surviving points are generated after applying each of the compatible nodes from the common dimensions. Greatest lower bounds (GLBs) are computed for each of the generated compatible points, and a set of options is generated comprising points from the generated compatible points and the computed GLBs.

    摘要翻译: 提供了计算机实现的系统和方法,用于减少呈现给用户的多个选项,其中选项具有排列在多维分层空间中的特征。 可以将系统和方法配置为使用维度点中的维度节点来识别公共维度,并通过确定关联是否存在来识别多维分层空间中的每个维度的兼容节点。 在从普通维度应用每个兼容节点之后生成兼容的幸存点对。 为每个生成的兼容点计算最大下限(GLB),并且生成包括来自所生成的兼容点和计算出的GLB的点的一组选项。

    Light amplifying devices for surface enhanced raman spectroscopy
    59.
    发明授权
    Light amplifying devices for surface enhanced raman spectroscopy 有权
    用于表面增强拉曼光谱的光放大装置

    公开(公告)号:US08542355B2

    公开(公告)日:2013-09-24

    申请号:US13383078

    申请日:2009-07-08

    IPC分类号: G01J3/44

    CPC分类号: G01N21/658 B82Y20/00

    摘要: A light amplifying device for surface enhanced Raman spectroscopy is disclosed herein. The device includes a dielectric layer having two opposed surfaces. A refractive index of the dielectric layer is higher than a refractive index of a material or environment directly adjacent thereto. At least one opening is formed in one of the two opposed surfaces of the dielectric layer, and at least one nano-antenna is established on the one of the two opposed surfaces of the dielectric layer. A gain region is positioned in the dielectric layer or adjacent to another of the two opposed surfaces of the dielectric layer.

    摘要翻译: 本文公开了一种用于表面增强拉曼光谱的光放大装置。 该装置包括具有两个相对表面的电介质层。 电介质层的折射率高于与其直接相邻的材料或环境的折射率。 至少一个开口形成在电介质层的两个相对表面之一中,并且至少一个纳米天线被建立在电介质层的两个相对表面之一上。 增益区域位于电介质层中或邻近电介质层的两个相对表面中的另一个。