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公开(公告)号：US07571004B2
公开(公告)日：2009-08-04
申请号：US11044761
申请日：2005-01-26
IPC分类号： A61N1/00
CPC分类号： A61N1/36046
摘要： The present invention is a method of improving the persistence of electrical neural stimulation, and specifically a method of improving the persistence of an image supplied to a retina, or visual cortex, through a visual prosthesis. A continuously stimulated retina, or other neural tissue, will desensitize after a time period in the range of 20 to 150 seconds. However, an interruption of the stimulation on the order of a few milliseconds will restore the retinal sensitivity without the user perceiving the interruption, or with the user barely perceiving the interruption.
摘要翻译： 本发明是一种改善电神经刺激持续性的方法，具体地说，一种改善通过视觉假体提供给视网膜或视觉皮层的图像的持续性的方法。 连续刺激的视网膜或其他神经组织将在20至150秒的时间段内脱敏。 然而，几毫秒级别的刺激的中断将恢复视网膜灵敏度，而不会使用户感觉到中断，或者用户几乎感觉到中断。
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公开(公告)号：US09764134B2
公开(公告)日：2017-09-19
申请号：US11881433
申请日：2007-07-27
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/3787
摘要： A visual prosthesis apparatus and a method for providing artificial vision are disclosed in the present disclosure. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured stimulate neural tissue in a subjects eye based on the stimulation patterns. An artificial vision may be provided by capturing a video image, converting the video image to stimulation patterns, and stimulating neural tissue in a subjects eye based on the stimulation patterns.
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公开(公告)号：US08224454B2
公开(公告)日：2012-07-17
申请号：US11523257
申请日：2006-09-18
申请人： Kelly H. McClure , Arup Roy , Sumit Yadav , Pishoy Maksy , Peter Meilstrup
发明人： Kelly H. McClure , Arup Roy , Sumit Yadav , Pishoy Maksy , Peter Meilstrup
IPC分类号： A61N1/00
CPC分类号： A61N1/36046 , A61N1/0543
摘要： The present invention is a method of neural stimulation and more specifically an improved method of providing flexible video/image possessing in a visual prosthesis by providing downloadable video filters. In a visual prosthesis, the input video image will, for the foreseeable future, be higher resolution than the output stimulation of the retina, optic nerve or visual cortex. This is due to limits of electrode array technology and the rapid advancement of video camera technology. It is therefore, advantageous to apply video processing algorithms (filters) to help provide the most useful information to the lower resolution electrode array. Different filters are more effective in different environments and for different subjects. Furthermore, filters will continue to improve over time. Examples of situation dependent filters include reverse image, contrast increasing, edge detection, segmentation using chromatic information and motion detection. Filters loaded in the video processing unit may be selected dynamically to suit the situation or the user's preference. It is therefore advantageous to provide flexibility in applying filters. However, it is also important to maintain the security necessary for a medical device. The present invention provides for an external (not implanted) video processing unit with downloadable video filters.
摘要翻译： 本发明是神经刺激的方法，更具体地，提供了一种通过提供可下载的视频滤波器来提供在视觉假体中拥有的灵活视频/图像的改进方法。 在视觉假体中，在可预见的将来，输入视频图像将比视网膜，视神经或视觉皮质的输出刺激更高的分辨率。 这是由于电极阵列技术的局限性和摄像机技术的飞速发展。 因此，应用视频处理算法（滤波器）有助于向较低分辨率电极阵列提供最有用的信息。 不同的过滤器在不同的环境和不同的科目中更有效。 此外，过滤器将随着时间的推移而持续改善。 情况相关滤波器的示例包括反向图像，对比度增加，边缘检测，使用色彩信息和运动检测的分割。 可以动态地选择加载在视频处理单元中的滤波器以适应情况或用户的偏好。 因此，提供应用过滤器的灵活性是有利的。 然而，保持医疗设备所需的安全性也是重要的。 本发明提供具有可下载的视频滤波器的外部（未植入）视频处理单元。
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公开(公告)号：US07738962B2
公开(公告)日：2010-06-15
申请号：US11357680
申请日：2006-02-16
申请人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
发明人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and The response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
摘要翻译： 本发明是一种将电极阵列自动调整为单个患者的神经特征的方法。 对电神经刺激的感知反应因患者而异，并且对电神经刺激的响应因患者而异，并且电流和感知亮度之间的关系通常是非线性的。 需要确定这种关系以适应每个患者的假体设置。 将感知反应映射到刺激是有利的。 本发明的映射方法是提供在电流，电压，脉冲持续时间，频率或某些其他维度上变化的多个刺激; 测量和记录对这些刺激的反应; 从各个点得出描述地图的公式或方程; 存储公式; 并使用该公式来映射未来的刺激。
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公开(公告)号：US20080188908A1
公开(公告)日：2008-08-07
申请号：US11924334
申请日：2007-10-25
申请人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
发明人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
IPC分类号： A61N1/08
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and The response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
摘要翻译： 本发明是一种将电极阵列自动调整为单个患者的神经特征的方法。 对电神经刺激的感知反应因患者而异，并且对电神经刺激的响应因患者而异，并且电流和感知亮度之间的关系通常是非线性的。 需要确定这种关系以适应每个患者的假体设置。 将感知反应映射到刺激是有利的。 本发明的映射方法是提供在电流，电压，脉冲持续时间，频率或某些其他维度上变化的多个刺激; 测量和记录对这些刺激的反应; 从各个点得出描述地图的公式或方程; 存储公式; 并使用该公式来映射未来的刺激。
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公开(公告)号：US20080097548A1
公开(公告)日：2008-04-24
申请号：US11926044
申请日：2007-10-28
申请人： Robert Greenberg , Kelly McClure , Arup Roy
发明人： Robert Greenberg , Kelly McClure , Arup Roy
IPC分类号： A61N1/00
CPC分类号： A61F9/08 , A61N1/36046 , A61N1/37276 , A61N1/3787 , G02C11/10 , H04N5/2254
摘要： A visual prosthesis apparatus and a method for limiting power consumption in a visual prosthesis apparatus. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit associated with the camera, the video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured to stop stimulating neural tissue in a subject's eye based on the stimulation patterns when an error is detected in a forward telemetry received from the video processing unit.
摘要翻译： 一种视觉假体装置和用于限制视力假体装置中的功率消耗的方法。 视觉假体装置包括用于捕捉视频图像的相机，与相机相关联的视频处理单元，视频处理单元，被配置为将视频图像转换为刺激图案;以及视网膜刺激系统，其被配置为停止刺激受试者的神经组织 基于在从视频处理单元接收的前向遥测中检测到错误时的刺激模式的眼睛。
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公开(公告)号：US20060184062A1
公开(公告)日：2006-08-17
申请号：US11357680
申请日：2006-02-16
申请人： Robert Greenberg , Ione Fine , Arup Roy , Matthew McMahon
发明人： Robert Greenberg , Ione Fine , Arup Roy , Matthew McMahon
IPC分类号： A61B19/00
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and The response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
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公开(公告)号：US20110015699A1
公开(公告)日：2011-01-20
申请号：US12879979
申请日：2010-09-10
申请人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
发明人： Robert Jay Greenberg , Ione Fine , Arup Roy , Matthew J. McMahon
IPC分类号： A61N1/36
CPC分类号： A61F9/08 , A61N1/36046
摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual patient. The perceptual response to electrical neural stimulation varies from patient to patient and The response to electrical neural stimulation varies from patient to patient and the relationship between current and perceived brightness is often non-linear. It is necessary to determine this relationship to fit the prosthesis settings for each patient. It is advantageous to map the perceptual responses to stimuli. The method of mapping of the present invention is to provide a plurality of stimuli that vary in current, voltage, pulse duration, frequency, or some other dimension; measuring and recording the response to those stimuli; deriving a formula or equation describing the map from the individual points; storing the formula; and using that formula to map future stimulation.
摘要翻译： 本发明是一种将电极阵列自动调整为单个患者的神经特征的方法。 对电神经刺激的感知反应因患者而异，并且对电神经刺激的响应因患者而异，并且电流和感知亮度之间的关系通常是非线性的。 需要确定这种关系以适应每个患者的假体设置。 将感知反应映射到刺激是有利的。 本发明的映射方法是提供在电流，电压，脉冲持续时间，频率或某些其他维度上变化的多个刺激; 测量和记录对这些刺激的反应; 从各个点得出描述地图的公式或方程; 存储公式; 并使用该公式来映射未来的刺激。
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59.发明申请公开(公告)号：US20100067825A1
公开(公告)日：2010-03-18
申请号：US12560581
申请日：2009-09-16
申请人： Chunhong Zhou , Arup Roy , Kelly H. McClure
发明人： Chunhong Zhou , Arup Roy , Kelly H. McClure
IPC分类号： G06K9/40
CPC分类号： G06T5/40 , A61N1/36046 , G06T5/009 , G06T2207/10016
摘要： Digital image filters and related methods for image contrast enhancement are disclosed. According to one aspect of the method, an invariant brightness level is initially determined. For each pixel of an input image, the invariant brightness level is subtracted from the input brightness of the pixel. The resulting value is multiplied with a contrast adjustment constant. After that, the invariant brightness level is added. Further aspects of the method can involve histogram equalization.
摘要翻译： 公开了用于图像对比度增强的数字图像滤波器和相关方法。 根据该方法的一个方面，初始确定不变亮度水平。 对于输入图像的每个像素，从像素的输入亮度中减去不变亮度电平。 结果值乘以对比度调整常数。 之后，添加不变亮度级别。 该方法的其它方面可以涉及直方图均衡。
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公开(公告)号：USD600440S1
公开(公告)日：2009-09-22
申请号：US29296571
申请日：2007-10-23
申请人： Sanjay Gaikwad , Arup Roy , Kelly H. McClure
设计人： Sanjay Gaikwad , Arup Roy , Kelly H. McClure
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