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公开(公告)号：US09205204B2
公开(公告)日：2015-12-08
申请号：US13567995
申请日：2012-08-06
申请人： Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
发明人： Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
CPC分类号： A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086
摘要： Wearable injection guides and manufacture and use thereof are described, which include: a rigid needle-penetrable material having an inner surface and an outer surface, the inner surface having form-fitting contours substantially conforming to a topography of a body region of an individual and the outer surface including one or more fiducials indication of at least one treatment parameter.
摘要翻译： 描述了可穿戴式注射引导件及其制造和使用，其包括：具有内表面和外表面的刚性可针穿透材料，内表面具有基本上符合个人身体区域的形貌的形状配合轮廓， 所述外表面包括至少一个治疗参数的一个或多个基准指示。
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公开(公告)号：US20110285579A1
公开(公告)日：2011-11-24
申请号：US12928703
申请日：2010-12-16
申请人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , David B. Tuckerman , Thomas A. Weaver , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , David B. Tuckerman , Thomas A. Weaver , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： G01S13/00
CPC分类号： G06Q30/02 , A61B5/0507 , A61B5/0816 , A61B5/165 , A61B5/7253 , G01S7/412 , G01S7/415 , G01S13/52 , G01S13/88
摘要： One or more human attributes extracted from a micro-impulse radar (MIR) signal is correlated to a temporary identity or phenotypic identity of a person.
摘要翻译： 从微脉冲雷达（MIR）信号提取的一个或多个人类属性与人的临时身份或表型身份相关。
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公开(公告)号：US09358350B2
公开(公告)日：2016-06-07
申请号：US13568033
申请日：2012-08-06
申请人： Mahalaxmi Gita Bangera , Edward S. Boyden , Hon Wah Chin , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
发明人： Mahalaxmi Gita Bangera , Edward S. Boyden , Hon Wah Chin , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
CPC分类号： A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086
摘要： Systems and methods for wearable injection guides are described, which include: acquiring one or more digital images of a body region of an individual with at least one image capture device; creating a digitally rendered model of a wearable injection guide from the one or more digital images of the body region of the individual; adding one or more digitally rendered fiducials indicative of at least one treatment parameter to the digitally rendered model of the wearable injection guide; and forming the wearable injection guide from the digitally rendered model of the wearable injection guide, the formed wearable injection guide including one or more fiducials corresponding to the one or more digitally rendered fiducials on the digitally rendered model of the wearable injection guide.
摘要翻译： 描述了可穿戴式注射引导件的系统和方法，其包括：用至少一个图像捕获装置获取个体的身体区域的一个或多个数字图像; 从个体的身体区域的一个或多个数字图像创建可戴式注射引导件的数字渲染模型; 将指示至少一个治疗参数的一个或多个数字呈现的基准添加到所述可佩戴注射引导件的数字渲染模型; 以及从所述可穿戴式注射导向器的数字渲染模型形成所述可穿戴式注射导向器，所述可穿戴式注射引导件包括与所述可穿戴式注射导向器的数字渲染模型上的所述一个或多个数字呈现的基准相对应的一个或多个基准。
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公开(公告)号：US20140039451A1
公开(公告)日：2014-02-06
申请号：US13567921
申请日：2012-08-06
申请人： Mahalaxmi Gita Bangera , Edward S. Boyden , Hon Wah Chin , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, JR.
发明人： Mahalaxmi Gita Bangera , Edward S. Boyden , Hon Wah Chin , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, JR.
IPC分类号： A61M5/42
CPC分类号： A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086
摘要： Wearable injection guides and manufacture and use thereof are described, which include: a rigid material formed to substantially conform in shape to a topography of a body region of an individual, the rigid material substantially impenetrable to an injection needle, and the rigid material including one or more injection needle access regions arranged in a treatment pattern.
摘要翻译： 描述了可穿戴的注射引导件及其制造和使用，其包括：刚性材料，形成为基本上符合个体的身体区域的形状，基本上不能穿透到注射针的刚性材料，并且刚性材料包括一个 或更多的注射针入口区域以治疗图案排列。
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公开(公告)号：US20120068876A1
公开(公告)日：2012-03-22
申请号：US12924036
申请日：2010-09-17
申请人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , David B. Tuckerman , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , David B. Tuckerman , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： G01S13/04
CPC分类号： G01S13/0209 , G01S7/415 , G01S13/04 , G06F3/017 , H04N21/42201 , H04N21/44218
摘要： A computer or entertainment system is configured to respond to data received from a micro impulse radar configured to detect movement, physiology, posture, presence, and/or absence of a person in one or more regions near the computer or entertainment system.
摘要翻译： 计算机或娱乐系统被配置为响应从被配置为检测计算机或娱乐系统附近的一个或多个区域中的人的运动，生理，姿势，存在和/或不存在的微脉冲雷达接收的数据。
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56.发明申请公开(公告)号：US20110166937A1
公开(公告)日：2011-07-07
申请号：US12925407
申请日：2010-10-20
申请人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , David B. Tuckerman , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , David B. Tuckerman , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： G06Q30/0261 , G06Q30/02 , G06Q30/0269 , G06Q99/00
摘要： A system and method for providing media and/or advertising content determines content and/or parameters responsive to physical and/or physiological information about a viewer detected by a micro-impulse radar (MIR).
摘要翻译： 用于提供媒体和/或广告内容的系统和方法确定响应于由微脉冲雷达（MIR）检测到的观看者的物理和/或生理信息的内容和/或参数。
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公开(公告)号：US20110276407A1
公开(公告)日：2011-11-10
申请号：US12930043
申请日：2010-12-22
申请人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , David B. Tuckeman , Thomas Weaver , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , David B. Tuckeman , Thomas Weaver , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： G06Q30/02 , G06Q30/0269
摘要： One or more micro-impulse radars (MIRs) are configured to determine the movement of at least one person. Media can be output to the person responsive to the movement.
摘要翻译： 一个或多个微脉冲雷达（MIR）被配置为确定至少一个人的移动。 可以将响应于移动的媒体输出给人。
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公开(公告)号：US09617157B2
公开(公告)日：2017-04-11
申请号：US12322367
申请日：2009-01-30
申请人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC分类号： C07K16/32 , A61K38/1703 , A61K38/1732 , A61K47/60 , A61K47/6871 , A61K47/6901 , B82Y5/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B21/0648 , C01B32/168 , C01B32/174 , C01B2202/02 , C01B2202/34 , C01B2202/36 , C01P2004/13 , Y02A50/473 , Y10S977/743 , Y10S977/75 , Y10S977/762 , Y10S977/788 , Y10S977/795 , Y10S977/848 , Y10S977/896 , Y10S977/915
摘要： Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. The tubular nanostructure is configured to interact with a lipid bilayer membrane and form a pore in the lipid bilayer membrane. The tubular nanostructure may be targeted by including at least one ligand configured to bind to one or more cognates on the lipid bilayer membrane of a target cell.
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公开(公告)号：US09187330B2
公开(公告)日：2015-11-17
申请号：US12283908
申请日：2008-09-15
申请人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC分类号： C07K16/32 , A61K38/1703 , A61K38/1732 , A61K47/60 , A61K47/6871 , A61K47/6901 , B82Y5/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B21/0648 , C01B32/168 , C01B32/174 , C01B2202/02 , C01B2202/34 , C01B2202/36 , C01P2004/13 , Y02A50/473 , Y10S977/743 , Y10S977/75 , Y10S977/762 , Y10S977/788 , Y10S977/795 , Y10S977/848 , Y10S977/896 , Y10S977/915
摘要： Devices, compositions, and methods are described which provide a tubular nanostructure targeted to a lipid bilayer membrane. The targeted tubular nanostructure can have a surface region configured to pass through a lipid bilayer membrane of a cell, a hydrophobic surface region flanked by two hydrophilic surface regions configured to form a pore in a lipid bilayer membrane of a cellular organelle, and at least one ligand configured to bind one or more cognates on the lipid bilayer membrane of the cellular organelle. The target cell can be, for example, a tumor cell, an infected cell, or a diseased cell in a subject. The tubular nanostructure can form a pore in the lipid bilayer membrane of the cellular organelle, e.g., mitochondria, which can permit transit or translocation of at least one compound across the membrane and cause cell death of the target cell.
摘要翻译： 描述了提供靶向脂质双层膜的管状纳米结构的装置，组合物和方法。 目标管状纳米结构可以具有被配置为穿过细胞的脂质双层膜的表面区域，侧壁有两个亲水性表面区域的疏水性表面区域，所述疏水性表面区域配置成在细胞器官细胞器的脂质双层膜中形成孔，以及至少一个 配体被配置为结合细胞器的脂质双层膜上的一个或多个同源物。 靶细胞可以是例如受试者中的肿瘤细胞，感染细胞或患病细胞。 管状纳米结构可以在细胞器（例如线粒体）的脂质双层膜中形成孔，其可以允许至少一种化合物跨过膜的转运或易位并导致靶细胞的细胞死亡。
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公开(公告)号：US10402927B2
公开(公告)日：2019-09-03
申请号：US13374748
申请日：2012-01-09
申请人： Roderick A. Hyde , Edward K. Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Royce A. Levien , Richard T. Lord , Robert W. Lord , Mark A. Malamud , John D. Rinaldo, Jr. , Dennis J. Rivet , Clarence T. Tegreene , Lowell L. Wood, Jr.
发明人： Roderick A. Hyde , Edward K. Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Royce A. Levien , Richard T. Lord , Robert W. Lord , Mark A. Malamud , John D. Rinaldo, Jr. , Dennis J. Rivet , Clarence T. Tegreene , Lowell L. Wood, Jr.
摘要： Structures and protocols are presented for signaling a decision (processing or transmitting a medical record or other resource, e.g.) conditionally, at least partly based on one or more performance indicia (excess hospital readmissions, e.g.) or therapeutic determinants (prior success, e.g.) or privacy considerations (patient consent, e.g.).
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