公开(公告)号：US07064110B2

公开(公告)日：2006-06-20

申请号：US10717290

申请日：2003-11-19

申请人： Yat Sun Or ,  Wang Guoqiang ,  Ly Tam Phan ,  Deqiang Niu ,  Nha Huu Vo ,  Yao-Ling Qiu ,  Yanchun Wang ,  Marina Busuyek ,  Ying Hou ,  Yulin Peng ,  Heejin Kim ,  Tongzhu Liu ,  Jay Judson Farmer ,  Guoyou Xu

发明人： Yat Sun Or ,  Wang Guoqiang ,  Ly Tam Phan ,  Deqiang Niu ,  Nha Huu Vo ,  Yao-Ling Qiu ,  Yanchun Wang ,  Marina Busuyek ,  Ying Hou ,  Yulin Peng ,  Heejin Kim ,  Tongzhu Liu ,  Jay Judson Farmer ,  Guoyou Xu

IPC分类号： A61K31/70 ,  C07H17/08

CPC分类号： C07H17/08

摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。