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公开(公告)号:US11224507B2
公开(公告)日:2022-01-18
申请号:US16506886
申请日:2019-07-09
Applicant: Edwards Lifesciences Corporation
Inventor: Matthew A. Peterson , Seung-Beom Yi , Siddharth Vad , Travis Zenyo Oba , Lauren R. Freschauf , Amanda French , Yaron Keidar , Yuanlong Du , Gregory Bak-Boychuk , Kevin M. Golemo , Alexander H. Cooper
IPC: A61F2/24
Abstract: A heart valve prosthesis for replacing a native mitral valve includes a self-expanding frame with a plurality of anchoring members disposed along the lower region. A valve body is positioned within the self-expanding frame and includes a plurality of leaflets configured to allow blood flow through the self-expanding frame in only one direction. A skirt surrounds the self-expanding frame and is spaced apart therefrom for contacting surrounding tissue and impeding blood flow around the self-expanding frame. The skirt may be reinforced with wires to help maintain a desired shape. The leaflets in the valve body are preferably connected to the self-expanding frame through one or more intermediate components such that the valve body is spaced radially inwardly from an inner surface of the self-expanding frame.
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公开(公告)号:US20200306038A1
公开(公告)日:2020-10-01
申请号:US16902773
申请日:2020-06-16
Applicant: Edwards Lifesciences Corporation
Inventor: Alexander H. Cooper , Matthew A. Peterson , William C. Brunnett
IPC: A61F2/24
Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.
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公开(公告)号:US20190262129A1
公开(公告)日:2019-08-29
申请号:US16286436
申请日:2019-02-26
Applicant: Edwards Lifesciences Corporation
Inventor: Alexander H. Cooper , Juliet Laura Schwartz , Wendy Vo Pham , Hieu Minh Luong , Julio Cesar Sanchez , Matthew A. Peterson , J. Brent Ratz , Lisong Ai
IPC: A61F2/24
Abstract: A mitral valve prosthesis includes an hourglass shaped inner frame and a bulbous outer frame. A valve body having a plurality of leaflets is positioned within an interior region of the inner frame. The leaflets are shaped to substantially conform to an interior surface of the inner frame when the leaflets are in an open position. As a result, the gap between the leaflets and the inner frame is decreased, thereby reducing the likelihood of thrombus formation. Ventricular anchors are preferably provided along a distal end of the inner frame. The anchors extend proximally for placement behind native mitral valve leaflets. A fabric skirt may extend along an inner or outer surface of the outer frame. In preferred embodiments, the fabric skirt extends distally beyond a distal end of the outer frame and is adapted for forming a seal along the mitral valve annulus.
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公开(公告)号:US20180353295A1
公开(公告)日:2018-12-13
申请号:US16104015
申请日:2018-08-16
Applicant: Edwards Lifesciences Corporation
Inventor: Alexander H. Cooper , Matthew A. Peterson
CPC classification number: A61F2/2436 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2002/9665 , A61F2220/0008 , A61F2230/005 , A61F2230/0052 , A61F2230/0067 , A61F2230/0069
Abstract: A method of replacing the function of a native mitral valve is achieved by inserting a distal end portion of a delivery apparatus into a patient's body, wherein a prosthetic mitral valve is disposed along the distal end portion of the delivery apparatus. The prosthetic mitral valve includes a collapsible and expandable annular body having a network of struts interconnected at a plurality of nodes to form a plurality of open cells. Atrial and ventricular flanges are coupled to the annular body and extend radially away from the annular body. Three commissure support posts extend from the ventricular flange toward a ventricular end of the prosthetic valve and a valve member is secured to the commissure support posts. The prosthetic mitral valve is positioned within the native mitral valve of the patient's heart and the native mitral valve is pinched between the atrial and ventricular flanges.
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公开(公告)号:US20180296336A1
公开(公告)日:2018-10-18
申请号:US16015003
申请日:2018-06-21
Applicant: Edwards Lifesciences Corporation
Inventor: Alexander H. Cooper , Matthew A. Peterson , William C. Brunnett
Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.
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公开(公告)号:US10010414B2
公开(公告)日:2018-07-03
申请号:US15382429
申请日:2016-12-16
Applicant: Edwards Lifesciences Corporation
Inventor: Alexander H. Cooper , Matthew A. Peterson , William C. Brunnett
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2436 , A61F2002/9534 , A61F2220/0008 , A61F2230/005 , A61F2230/0065 , A61F2230/0078
Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.
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公开(公告)号:US09757232B2
公开(公告)日:2017-09-12
申请号:US14707607
申请日:2015-05-08
Applicant: Edwards Lifesciences Corporation
Inventor: Matthew A. Peterson , Robert C. Taft , Devin H. Marr , Minh T. Ma , Seung-Beom Yi , Ryan Silva
CPC classification number: A61F2/2427 , A61F2/24 , A61F2/2418 , A61F2/95 , A61F2002/9522 , A61F2230/0013 , A61F2230/005 , B21D11/08 , B21D37/00 , B21D39/048
Abstract: Embodiments of an apparatus, and a method for crimping expandable stents or prosthetic valves having a radially expandable and compressible annular body and one or more protruding anchors extending from the body using the apparatus, where the apparatus comprise a housing, a plurality of circumferentially arranged nesting jaws, and an actuator configured to move the jaws radially inwardly to reduce the size of the crimping aperture, thereby radially compressing the annular body of the prosthetic valve or stent. In particular embodiments, a selected set of the jaws, each having a front side and a recessed portion in its front side adjacent to its inner end. The recessed portions of the selected jaws collectively are sized and shaped to receive the one or more anchors of the prosthetic valve when the annular body is positioned within the crimping aperture.
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公开(公告)号:US20140222136A1
公开(公告)日:2014-08-07
申请号:US14171603
申请日:2014-02-03
Applicant: Edwards Lifesciences Corporation
Inventor: Stephen C. Geist , Robert C. Taft , Travis Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61B6/4441 , A61B8/12 , A61F2/2409 , A61F2/2412 , A61F2/2436 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0018 , A61F2250/0029 , A61F2250/0069
Abstract: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. One embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve member. In some cases, the prosthetic valves also include ventricular anchors and/or an atrial portion coupled to and disposed outside of the main body. Methods, devices, and systems for delivering such prosthetic valves to the native mitral valve and implanting them therein are also provided.
Abstract translation: 提供了用于植入在天然二尖瓣内的人工瓣膜的实施例。 假体瓣膜的一个实施例包括可径向压缩的主体和单向阀构件。 在一些情况下,假体瓣膜还包括联接到并设置在主体外侧的心室锚和/或心房部分。 还提供了用于将这种假性瓣膜递送到天然二尖瓣并将其植入其中的方法,装置和系统。
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