摘要:
A dialysis apparatus having a unit for the production of the dialysis solution and a dialyzer includes a first detector mounted upstream of the dialyzer and a second detector mounted downstream of the dialyzer by means of which the composition of the dialysis solution can be regulated. The measuring data of detectors are compared and eventually used to control the composition of the dialysis solution; the invention is particularly useful in high exchange capacity dialyzers, since the composition of the dialysis solution can be adjusted directly and at any time to maintain desired conditions in the dialyzed patient.
摘要:
Device for introducing a specimen into and withdrawing the same from the interior of a chamber sealed from the surrounding environment. The device includes a test bar slidably and sealingly projecting through an opening in the chamber. The test bar has a first length portion which includes a specimen-supporting arrangement and which has a part that is in a sealing relationship with the opening in a first end position of the test bar in which the specimen-supporting arrangement is situated inside the chamber. The test bar further has a second length portion which has a part that is in a sealing relationship with the opening in a second end position of the test bar in which the specimen-supporting arrangement is situated externally of the chamber. A releasable coupling device detachably connects the two length portions of the test bar to one another.
摘要:
Treating of localized bacterial infection, comprising locally applying Taurolidine to the infection. A device for insertion into the body, the device comprising Taurolidine to render the device infection resistant. A medication for treating bacterial infections, comprising Taurolidine carried by one of: gels, liquid, thixotropic gels, colloidal mixtures, dispensal suspensions, injectable polymers, or a microparticle. A method for treating blood, comprising: removing blood from the body; treating the blood with Taurolidine; and returning the treated blood.
摘要:
A cartridge for treating medical or biological fluid includes a first cap having an inlet for the fluid, a container including a plurality of compartments and a second cap including an outlet for the fluid, wherein each compartment contains a plurality of particles, wherein the fluid is adapted to flow through the compartments and react with the plurality of particles.
摘要:
Catheters used for medical treatment, e.g., hemodialysis are filled with a locking solution, usually heparin between treatments. To prevent infections, antimicrobial or antibiotic substances have been used as locking solution alone or in combination with antithrombotic substances. It has been found that these locking solutions are rapidly washed out from the catheter tip. The invention describes a thixotropic gel that can be used as locking solution. Beneficial substances, e.g., antimicrobial or antibiotic substances can be added to the gel. A preferred antimicrobial substance is taurolidin alone or in combination with salicylic acid or one of its salts.
摘要:
A method for measurement of mass and energy transfer parameters (clearance and dialysance) in hemodialysis. A sensor is provided in the dialysate flow path downstream of the dialyzer and means are provided to add concentrate upstream of the dialyzer. A pre-determined amount of a substance whose dialysance is to be measured is added upstream of the dialyzer. The amount of substance riot dialyzed in the dialyzer is measured downstream of the dialyzer by said sensor by integrating the concentration over time. Dialysance is calculated from the amount added upstream, the amount measured downstream and the dialysate flow. In case the substance is part of the dialysate the base concentration is subtracted during integration. The addition of the concentrate upstream of the dialyzer can be done manually or, alternatively by the mixing pump of the dialysis machine. Instead of an increase of the concentration with a concentrate dilution with water can be used as well.
摘要:
Stenosis in a blood access circuit (graft, fistula) or in an extracorporeal circuit are detected by monitoring pressure pulses in the extracorporeal circuit created either by the heart or by the peristaltic blood pump of the extracorporeal circuit. By monitoring pressure pulses created by the. peristaltic blood pump loss of occlusion of the blood pump can be detected. Measurement of the pressure pulses is done either with sensors already built into the blood treatment equipment or, according to the invention, with sensors mechanically coupled to the wall of the blood tubing. The deviation of a pressure pulse amplitude proportional signal from a predetermined value indicates stenosis or loss of occlusion, respectively.
摘要:
An extracorporeal blood circuit is disclosed for withdrawing, filtering and returning blood from peripheral blood vessels. The blood passage in the circuit extends through a withdrawal tube connected to a catheter in a peripheral vein, a filter, one or more pressure sensors and return tube also connected to a catheter in a peripheral vein (which may or may not be the same vein as used for the withdrawal tube). The blood passage is air free, and has smooth passage walls which promoted continuous and uniform flow of the blood through the circuit.
摘要:
An improvement in an implantable port of the type including a housing that is implanted within a subcutaneous tissue pocket is disclosed, wherein the improvement comprises the presence of metallic silver, an inorganic silver compound, a silver salt of an organic acid, or other antimicrobial substances such as taurolidine on the surfaces of the port in contact with, or proximate to, the tissue of said pocket.
摘要:
Apparatus and methods for providing sterile substitution solutions from a dialysis fluid used in connection with the treatment of a patient's blood in an extracorporeal circuit are disclosed. The apparatus includes pumps or valves for comparing the flow of fresh dialysis fluid prior to treatment and after treatment of a patient's blood and a throttle which divides the fresh dialysis circuit into a positive pressure portion and a negative pressure portion, a sterile filter including a membrane disposed in the positive pressure portion of the dialysis circuit, and a valve for controlling the pressure in the positive pressure portion to pass a predetermined amount of the fresh dialysis fluid through the membrane in a sterile filter to provide a predetermined amount of the sterile substitution solution for addition to the extracorporeal circuit.