Method and apparatus for sensing cardiac contractile function

    公开(公告)号:US20060041298A1

    公开(公告)日:2006-02-23

    申请号:US11254344

    申请日:2005-10-20

    IPC分类号: A61N1/05

    摘要: Systems and methods for detecting and measuring cardiac contractile function of a heart using an acceleration sensor unit inserted within the heart, such as within a vein of the cardiac wall are disclosed. The systems and methods involve detecting the occurrence of electrical events within the patient's heart by inserting and positioning an implantable lead having an electrode near a cardiac wall as well as detecting mechanical events within the patient's heart by then inserting and positioning a cardiac motion sensor unit through the inner lumen of the implantable lead. Furthermore, the systems and methods do not require dedicated leads and may be used with preexisting implantable leads.

    Method and system for setting cardiac resynchronization therapy parameters
    53.
    发明申请
    Method and system for setting cardiac resynchronization therapy parameters 有权
    设置心脏再同步治疗参数的方法和系统

    公开(公告)号:US20050137630A1

    公开(公告)日:2005-06-23

    申请号:US10744237

    申请日:2003-12-22

    IPC分类号: A61N1/362 A61N1/368

    摘要: A method or system for computing and/or setting optimal cardiac resynchronization pacing parameters as derived from intrinsic conduction data is presented. The intrinsic conduction data includes intrinsic atrio-ventricular and interventricular delay intervals which may be collected via the sensing channels of an implantable cardiac device. Among the parameters which may be optimized in this manner are an atrio-ventricular delay interval and a biventricular offset interval. In one of its aspects, the invention provides for computing optimum pacing parameters for patients having some degree of AV block or with atrial conduction deficits. Another aspect of the invention relates to a pacing mode and configuration for providing cardiac resynchronization therapy to patients with a right ventricular conduction disorder.

    摘要翻译: 提出了一种用于计算和/或设置从内在传导数据导出的最佳心脏再同步起搏参数的方法或系统。 内在传导数据包括可通过可植入心脏装置的感测通道收集的本征心室和室间延迟间隔。 可以以这种方式优化的参数是心房延迟间隔和双心室偏移间隔。 在其一个方面,本发明提供了对具有一定程度的AV阻滞或具有心房传导缺陷的患者计算最佳起搏参数。 本发明的另一方面涉及用于向患有右心室传导障碍的患者提供心脏再同步治疗的起搏模式和配置。

    Method and apparatus for predicting acute response to cardiac resynchronization therapy

    公开(公告)号:US06766189B2

    公开(公告)日:2004-07-20

    申请号:US09822790

    申请日:2001-03-30

    IPC分类号: A61B106

    CPC分类号: A61N1/3627 A61N1/3682

    摘要: A method and apparatus for predicting acute response to cardiac resynchronization therapy is disclosed. The method can comprise measuring a first interval during an intrinsic systolic cycle and measuring a second interval during a stimulated systolic cycle. The acute response can be predicted by comparing the percent change in duration between the first interval and the second interval against a pre-determined threshold value. The first and second time intervals can be measured using, for example, a surface ECG or, alternatively, an intracardiac electrogram. In one embodiment, the first interval can be the duration of an intrinsic QRS complex measured during a non-stimulated systolic cycle. Similarly, the second interval can be the duration of a stimulated QRS complex measured during a stimulated systolic cycle.

    Automatic selection of stimulation chamber for ventricular resynchronization therapy

    公开(公告)号:US06622040B2

    公开(公告)日:2003-09-16

    申请号:US09738407

    申请日:2000-12-15

    IPC分类号: A61N1362

    摘要: A method and apparatus for selection of one or more ventricular chambers to stimulate for ventricular resynchronization therapy. Intrinsic intracardia electrograms that include QRS complexes, are recorded from a left and right ventricle. A timing relationship between the intrinsic intracardia electrograms recorded from the left and right ventricle is then determined. In one embodiment, the timing relationship is determined using a delay between a left ventricular and a right ventricular sensed intrinsic ventricular depolarizations and a duration interval of one or more QRS complexes. In one embodiment, the duration of QRS complexes is determined from either intracardiac electrograms or from surface ECG recordings. One or more ventricular chambers in which to provide pacing pulses are then selected based on the timing relationship between intrinsic intracardia electrograms recorded from the right and left ventricle, and the duration of one or more QRS complexes.

    Patient identification for the pacing therapy using LV-RV pressure loop
    56.
    发明授权
    Patient identification for the pacing therapy using LV-RV pressure loop 有权
    使用LV-RV压力回路进行起搏治疗的患者鉴定

    公开(公告)号:US06280389B1

    公开(公告)日:2001-08-28

    申请号:US09439228

    申请日:1999-11-12

    IPC分类号: A61B5021

    摘要: A method and apparatus for determining whether a patient with congestive heart failure (CHF) will benefit from pacing therapy through the use of an implantable cardiac rhythm management device. A patient's right ventricular and left ventricular pressures are measured, and the patient's PP_Area is calculated for each normal heartbeat that occurs during the testing period. Depending upon the value of the patient's mean PP_Area, it can be determined whether the patient will or will not respond well acutely to pacing therapy. A mean PP_Area value of greater than or equal to a predetermined threshold, which is about 0.3, indicates that the patient is a responder to pacing therapy, while a value of less than the predetermined threshold of about 0.3 indicates that the patient is a non-responder.

    摘要翻译: 一种用于确定患有充血性心力衰竭(CHF)的患者是否将通过使用植入式心律管理装置从起搏治疗中受益的方法和装置。 测量患者的右心室和左心室压力,并计算在测试期间发生的每个正常心跳的患者的PP_Area。 根据患者平均PP_Area的价值,可以确定患者是否会或不会对起搏治疗产生很好的反应。 大于或等于预定阈值(约0.3)的平均PP_Area值表示患者是起搏治疗的应答​​者,而小于约0.3的预定阈值的值表示患者是非 - 响应者。

    Method and apparatus for determing the coronary sinus vein branch accessed by a coronary sinus lead
    57.
    发明授权
    Method and apparatus for determing the coronary sinus vein branch accessed by a coronary sinus lead 有权
    用于确定冠状静脉窦导管接近的冠状静脉窦静脉分支的方法和装置

    公开(公告)号:US08478390B2

    公开(公告)日:2013-07-02

    申请号:US13488085

    申请日:2012-06-04

    IPC分类号: A61B5/0452

    摘要: Systems and methods for determining the coronary sinus vein branch location of a left ventricle electrode are disclosed. The systems and methods involve detecting the occurrence of electrical events within the patient's heart including sensing one or more of the electrical events with the electrode and then analyzing the electrical events to determine the electrode's position. The determination of electrode position may be used to automatically adjust operating parameters of a VRT device. Furthermore, the determination of electrode position may be made in real-time during installation of the electrode and a visual indication of the electrode position may be provided on a display screen.

    摘要翻译: 公开了用于确定左心室电极的冠状静脉窦静脉分支位置的系统和方法。 系统和方法涉及检测患者心脏内的电事件的发生,包括用电极感测一个或多个电事件,然后分析电气事件以确定电极的位置。 电极位置的确定可用于自动调整VRT器件的工作参数。 此外,可以在电极的安装期间实时地确定电极位置,并且可以在显示屏上提供电极位置的视觉指示。

    METHOD AND APPARATUS FOR DETERMING THE CORONARY SINUS VEIN BRANCH ACCESSED BY A CORONARY SINUS LEAD
    59.
    发明申请
    METHOD AND APPARATUS FOR DETERMING THE CORONARY SINUS VEIN BRANCH ACCESSED BY A CORONARY SINUS LEAD 有权
    用于确定冠状动脉导管接收的冠状动脉支架的方法和装置

    公开(公告)号:US20120238889A1

    公开(公告)日:2012-09-20

    申请号:US13488085

    申请日:2012-06-04

    IPC分类号: A61B5/042 A61N1/365

    摘要: Systems and methods for determining the coronary sinus vein branch location of a left ventricle electrode are disclosed. The systems and methods involve detecting the occurrence of electrical events within the patient's heart including sensing one or more of the electrical events with the electrode and then analyzing the electrical events to determine the electrode's position. The determination of electrode position may be used to automatically adjust operating parameters of a VRT device. Furthermore, the determination of electrode position may be made in real-time during installation of the electrode and a visual indication of the electrode position may be provided on a display screen.

    摘要翻译: 公开了用于确定左心室电极的冠状静脉窦静脉分支位置的系统和方法。 系统和方法涉及检测患者心脏内的电事件的发生,包括用电极感测一个或多个电事件,然后分析电气事件以确定电极的位置。 电极位置的确定可用于自动调整VRT器件的工作参数。 此外,可以在电极的安装期间实时地确定电极位置,并且可以在显示屏上提供电极位置的视觉指示。