利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

59 条记录 (耗时 0.026 秒)

    METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS
    51.
    发明申请
    METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS 审中-公开
    使用组织氧化测量法进行后期评估的方法和装置

    公开(公告)号：US20110066017A1

    公开(公告)日：2011-03-17

    申请号：US12609514

    申请日：2009-10-30

    申请人： Jonathan L. Kuhn

    发明人： Jonathan L. Kuhn

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14551 ,  A61B5/1459 ,  A61B5/6846 ,  A61B5/7285 ,  A61N1/36557 ,  A61N1/3925 ,  A61N1/3956

    摘要： A method and apparatus for controlling delivery of therapy that includes an emitting portion emitting light at a predetermined emitted light intensity to a volume of tissue at a plurality of wavelengths, and a detecting portion detecting the emitted light scattered by the volume of tissue to generate corresponding detected light intensity output signals. A control module controls the light emission so that an emitted light intensity at each of the plurality of wavelengths is within a predetermined intensity range, and determines a tissue oxygenation index in response to only the detected light intensity output signals, and a therapy delivery module delivers therapy in response to the determined tissue oxygenation index.

    摘要翻译： 一种用于控制治疗递送的方法和装置，其包括以预定的发射光强度发射多个波长的组织体积的发射部分，以及检测部分，其检测由组织体积散射的发射光，以产生相应的 检测到光强输出信号。 控制模块控制发光，使得在多个波长中的每个波长处的发射光强度在预定强度范围内，并且响应于检测到的光强度输出信号确定组织氧合指数，并且治疗递送模块递送 响应于确定的组织氧合指数的治疗。

    Method and apparatus for calibrating an absolute oxygen saturation sensor
    53.
    发明授权
    Method and apparatus for calibrating an absolute oxygen saturation sensor 有权
    用于校准绝对氧饱和度传感器的方法和装置

    公开(公告)号：US08781547B2

    公开(公告)日：2014-07-15

    申请号：US13283930

    申请日：2011-10-28

    申请人： Jonathan L. Kuhn

    发明人： Jonathan L. Kuhn

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14551 ,  A61B5/1495

    摘要： A method for using a medical device comprising an optical sensor to measure calibrated oxygen saturation in a body tissue uses a standard spectral response of blood established for multiple of oxygen saturations and a standard spectral response of a reference material. The standard responses are established using a spectrometer. The spectral power output of the optical sensor is measured using a spectrometer. The optical sensor output signal response to the reference material is obtained. A processor computes a device-specific calibration curve for the medical device using the measured spectral power output and the standard spectral response of blood and computes an optical gain using the standard spectral response of the reference material and the measured spectral power output of the optical sensor. The device-specific calibration curve and optical gain of the optical sensor are stored in a memory of the medical device.

    摘要翻译： 使用包括光学传感器来测量身体组织中的校准氧饱和度的医疗装置的方法使用针对多个氧饱和度建立的血液的标准光谱响应和参考材料的标准光谱响应。 使用光谱仪建立标准响应。 使用光谱仪测量光学传感器的光谱功率输出。 获得对参考材料的光学传感器输出信号响应。 处理器使用测量的光谱功率输出和血液的标准光谱响应来计算医疗设备的设备特定校准曲线，并使用参考材料的标准光谱响应和光学传感器的测量光谱功率输出来计算光学增益 。 光学传感器的器件专用校准曲线和光学增益被存储在医疗设备的存储器中。

    IMPLANTABLE MEDICAL SYSTEM INCLUDING MULTIPLE SENSING MODULES
    54.
    发明申请
    IMPLANTABLE MEDICAL SYSTEM INCLUDING MULTIPLE SENSING MODULES 审中-公开
    包括多个传感模块的可植入医疗系统

    公开(公告)号：US20100030043A1

    公开(公告)日：2010-02-04

    申请号：US12182484

    申请日：2008-07-30

    申请人： Jonathan L. Kuhn

    发明人： Jonathan L. Kuhn

    IPC分类号： A61B5/1459 ,  A61B5/01 ,  A61B5/0215 ,  A61B5/11

    CPC分类号： A61B5/0086 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/14542 ,  A61B5/1459 ,  A61N1/36542 ,  A61N1/3655 ,  A61N1/36557 ,  A61N1/36564 ,  A61N1/36578

    摘要： A medical system includes at least two sensing modules that each generate an optical signal that changes as a function of a physiological parameter of a patient. The sensing modules may be coupled to a common light source and a common receiver via an optically transmissive member. At least a first sensing module that is closest to the light source along a length of the optically transmissive member may include a waveguide to split the light emitted by the light source. A first portion of the light may be directed toward the first sensing module and a second portion of the light may be directed toward a second sensing module that is placed downstream of the first sensing module in a direction substantially along the direction of light flow through the optically transmissive member and away from the light source.

    摘要翻译： 医疗系统包括至少两个感测模块，每个感测模块产生作为患者的生理参数的函数而变化的光学信号。 感测模块​​可以经由光学透射构件耦合到公共光源和公共接收器。 至少沿着光学透射构件的长度最靠近光源的第一感测模块可以包括用于分离由光源发射的光的波导。 光的第一部分可以被引导到第一感测模块，并且光的第二部分可以被引导到第二感测模块，该第二感测模块沿着基本沿着沿着光流的方向的方向被放置在第一感测模块的下游 透光构件并远离光源。

    Moment fraction computation for sensors
    56.
    发明授权
    Moment fraction computation for sensors 有权
    传感器的时刻分数计算

    公开(公告)号：US08720276B2

    公开(公告)日：2014-05-13

    申请号：US13176018

    申请日：2011-07-05

    申请人： Jonathan L. Kuhn ,  Jonathan P. Roberts ,  James D. Reinke ,  Richard J. O'Brien ,  Michael B. Terry ,  Kamal Deep Mothilal

    发明人： Jonathan L. Kuhn ,  Jonathan P. Roberts ,  James D. Reinke ,  Richard J. O'Brien ,  Michael B. Terry ,  Kamal Deep Mothilal

    IPC分类号： G01L7/00

    CPC分类号： G01L9/125 ,  A61B5/00 ,  A61B5/0215 ,  A61B5/031 ,  A61B5/036 ,  A61B5/205 ,  A61B5/42 ,  G01L15/00 ,  G01L19/02 ,  G01L19/149

    摘要： An implantable medical sensor system provides signals representative of a magnitude of moment fraction applied to a sensor module at a selected site. A sensor module includes a first transducer producing a first signal having an associated first response to pressure and strain applied to the sensor module and a second transducer producing a second signal having an associated second response to pressure and strain applied to the sensor module. A moment fraction is computed in response to the first signal and the second signal. In various embodiments, the moment fraction is used to guide positioning of the sensor module, indicate a need for repositioning the sensor module, report loading of the sensor module during normal operation for use as sensor design information and in setting sensor calibration ranges.

    摘要翻译： 可植入医疗传感器系统提供表示在所选位置处施加到传感器模块的力矩分数的大小的信号。 传感器模块包括第一传感器，其产生具有对施加到传感器模块的压力和应变的相关联的第一响应的第一信号，以及产生具有对施加到传感器模块的压力和应变的相关联的第二响应的第二信号的第二传感器。 响应于第一信号和第二信号计算力矩分数。 在各种实施例中，力矩分数用于引导传感器模块的定位，指示需要重新定位传感器模块，在正常操作期间报告传感器模块的负载，以用作传感器设计信息和设置传感器校准范围。

    MONITORING OF TISSUE HEMOGLOBIN CONCENTRATION
    58.
    发明申请
    MONITORING OF TISSUE HEMOGLOBIN CONCENTRATION 有权
    组织HEMOGLOBIN浓度的监测

    公开(公告)号：US20120108925A1

    公开(公告)日：2012-05-03

    申请号：US12913096

    申请日：2010-10-27

    申请人： Jonathan L. Kuhn

    发明人： Jonathan L. Kuhn

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/1455 ,  A61B5/0031 ,  A61B5/14535 ,  A61B5/14551 ,  A61B5/7239

    摘要： A medical device system and associated method monitor tissue hemoglobin concentration. Light attenuation is measured in a volume of tissue in a patient. A value of a tissue scattering coefficient corresponding to the tissue volume in the patient is established in response to the attenuation measurement. A second derivative of the light attenuation measurement is determined. An artifact correction term is computed in response to the established tissue scattering coefficient, and a tissue hemoglobin concentration is computed using the artifact correction term and the second derivative.

    摘要翻译： 医疗器械系统及相关方法监测组织血红蛋白浓度。 在患者的组织体积中测量光衰减。 响应于衰减测量建立与患者组织体积相对应的组织散射系数的值。 确定光衰减测量的二阶导数。 根据建立的组织散射系数计算人工制品校正项，并使用伪影校正项和二次导数计算组织血红蛋白浓度。

    METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS
    59.
    发明申请
    METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS 有权
    使用组织氧化测量法进行后期评估的方法和装置

    公开(公告)号：US20110066018A1

    公开(公告)日：2011-03-17

    申请号：US12609538

    申请日：2009-10-30

    申请人： Jonathan L. Kuhn

    发明人： Jonathan L. Kuhn

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14551 ,  A61B5/1459 ,  A61B5/6846 ,  A61B5/7285 ,  A61N1/36557 ,  A61N1/3925 ,  A61N1/3956

    摘要： A method and apparatus for controlling delivery of therapy that includes an emitting portion emitting light at a predetermined emitted light intensity to a volume of tissue at a plurality of wavelengths, and a detecting portion detecting the emitted light scattered by the volume of tissue to generate corresponding detected light intensity output signals. A control module adjusts the detected light intensity output signals for shifts in intensity corresponding to the emitted light intensity, and determines a tissue oxygenation index in response to only the adjusted detected light intensity output signals, and a therapy delivery module controlling therapy in response to the determined tissue oxygenation index.

    摘要翻译： 一种用于控制治疗递送的方法和装置，其包括以预定的发射光强度发射多个波长的组织体积的发射部分，以及检测部分，其检测由组织体积散射的发射光，以产生相应的 检测到光强输出信号。 控制模块调整检测到的光强度输出信号，用于与发射的光强度相对应的强度偏移，并且仅响应于经调整的检测到的光强度输出信号确定组织氧合指数，以及治疗递送模块， 确定组织氧合指数。