摘要:
This invention relates to a thiazolidinedione derivative represented by the following formula (1): ##STR1## wherein R.sup.1 and R.sup.2 individually represent H, a halogen atom, or a halogen-substituted or -unsubstituted lower alkyl or alkoxy group, and R.sup.1 and R.sup.2 may be coupled together to form a ring of an alkylenedioxy chain, X represents a nitrogen atom or a CH group, A represents a substituted or unsubstituted imidazolidinone, pyrrolidinone, imidazole or pyrazole ring, or a salt thereof; and a pharmaceutical composition containing the thiazolidinedione derivative or a salt thereof. The above compound has excellent blood sugar-lowering action and blood lipid-lowering action and is useful as a therapeutic agent for diabetes.
摘要:
The present invention pertains to a transfer press which achieves a reduction in the overall length of the press line and, hence, in the total weight, while ensuring high efficiency and safety of preparatory work, such as changing of idle nests, owing to a facility which permits such a preparatory work to be performed externally of the press. To these ends, the transfer press has: an upright (3) disposed between and commonly possessed by adjacent press units (P1, P2); locating means (4A, 2A) for locating adjacent crowns (4, 4) with respect to each other and adjacent beds (2, 2) with respect to each other, respectively; and a tie rod (7) extending through the boundary between the adjacent beds (2, 2) and through the boundary between the adjacent crowns (4, 4), the adjacent crowns (4, 4) and the adjacent beds (2, 2) respectively being tied together through the upright (3).
摘要:
A fixing part having a room in which a metal attachment leg is inserted to attach a capacitor unit is disposed on an outside face of a case. An electrode connected to a terminal of a capacitor element is disposed in the fixing part, and a lock part to be engaged with the inserted metal attachment leg is disposed, whereby when the metal attachment leg is inserted into the fixing part, the electrode of the fixing part is electrically contacted to the metal attachment leg by elasticity.
摘要:
A transfer press, capable of being easily transported, capable of being adjusted flexibly to changes in specifications, and capable of eliminating the idling of the transfer feeder, has a body (1) which is divided into a bed (2), uprights (3) provided vertically upon the bed, a pair of supporting beams (4) provided upon the uprights and disposed in spaced relationship with each other in a horizontal direction perpendicular to the direction in which a workpiece is fed, and a plurality of pressing units (5) each of which is independently provided for a respective one of a plurality of pressing operations. Each of the pressing units (5) comprises a crown (6) accommodating a slide-driving mechanism (8), and a slide (7). The crowns (6), provided for the individual pressing operations, are removably mounted upon the supporting beams (4). Slide guides (12) for guiding the vertical motion of the slides (7) are also provided on the supporting beams (4).
摘要:
A device for estimating a temperature of a working oil in a shock absorber in a suspension system which connects a sprung member and an unsprung member of a motor vehicle, wherein the temperature of the oil is estimated on the basis of at least detected vertical acceleration of the sprung member. The device may be suitably incorporated in an apparatus for controlling the damping characteristic of the shock absorber, wherein an actuator is operated by a controller for changing the damping characteristic, and the controller includes the temperature estimating device, and a device for inhibiting an operation of the actuator to control the damping characteristic when the oil temperature estimated by the temperature estimating device is lower than a predetermined threshold.
摘要:
A thiazolidine derivative represented by the following formula (1): ##STR1## X represents a carbon atom or nitrogen atom, Y represents an oxygen atom or an imino group; A and B individually represent a lower alkylene group, m stands for 0 or 1, and a method of treatment of diabetes by administration of the compound.
摘要:
An oxazolidine derivative represented by the formula (I) ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are H, optionally halogenated alkyl, optionally halogenated alkoxy, OH, halo, NO.sub.2, amino optionally having acetyl or alkyl, COOH, alkoxycarbonyl, CN, alkanoyl, 2-oxazolyl, or R.sup.1 and R.sup.2 may be combined with each other to represent --(CH.sub.2).sub.p -- or --O(CH.sub.2).sub.q O-- (p is 3-5, q is 1-3) to form a ring, m and n are each 0 or 1, R.sup.4 and R.sup.5 are H or alkyl, X is C or N, Y is CH.sub.2 OH, CHO or COOR.sup.6 (R.sup.6 is alkyl, benzyl or H), A is alkylene, carbonyl or sulfonyl, B is alkylene, E is alkylene which may be substituted with halo or is alkenylene, Z is O or S, except for a compound wherein n is 0, m is 1 and Y is CH.sub.2 OH, and except for a compound wherein n is 0, Y is COOR.sup.6 (R.sup.6 is alkyl), a salt thereof, a process for its preparation, anti-hyperlipidemic composition containing the derivative as an active ingredient and a method for treating hyperlipidemia comprising administering the derivative.
摘要:
The car locking device of the present invention has a latch to be engaged with a striker, a ratchet for preventing the reversal of said latch, an opening lever for disengaging said ratchet from said latch, a locking lever for changing over said intermediate lever and said opening lever between an engaged state (unlocked state) or a disengaged state (locked state), and the first and second change-over levers. The key device of a door is connected to said first change-over lever, and said locking lever is connected to said second change-over lever. Said first and second change-over levers are rotationally moved together by key operation between the locking position and the unlocking position, and in the case of the excessive turn beyond the unlocking position, the first change-over lever only is rotationally moved, with said second change-over lever and said lock lever kept stationary. The excessive turn of said first change-over lever is detected by a switch, and when the switch is turned "On", the locking devices of other doors are also interlocked to be changed over into the unlocked state.
摘要:
This invention provides a 1,1,2-triaryl-1-butene derivative of the formula ##STR1## wherein R.sub.1 and R.sub.2 each represent a lower alkyl group, one of R.sub.3 and R.sub.4 is a lower alkyl group and the other is a group of the formula ##STR2## (in which R.sub.5 is a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom or --OPO(OH).sub.2 group); or a pharmacologically acceptable salt thereof, its preparation and agents containing the derivative for treating mammary cancer and anovulatory infertility.
摘要:
A rotating polygon mirror includes a polygon cylinder having a reflection mirror surface formed on at least one of the sides thereof, and mount portions formed on an upper surface and a lower surface thereof, which are to be held by mount members of a laser scan type optical system. At least one of the mount portions on the upper and lower surfaces has such a shape that, when two rotating polygon mirrors are stacked with their non-corresponding mount portions abutting each other, a reference surface formed in at least one of the mount portions of one rotating polygon mirror does not contact the mount portion of the other rotating polygon mirror.