公开(公告)号：US08568364B2

公开(公告)日：2013-10-29

申请号：US13139919

申请日：2009-12-18

申请人： David Plumptre

发明人： David Plumptre

IPC分类号： A61M5/32 ,  A61M3/00 ,  A61M5/00

CPC分类号： A61M5/3213 ,  A61M5/3129 ,  A61M2205/583 ,  A61M2205/60

摘要： A drug delivery device (1) comprises a housing (2) and a cap (3) attachable onto the housing (2). The cap (3) comprises one or more snap features (33) to attach the cap (3) onto the housing (2) and one or more orientation features (34) to define the orientation of the cap (3) relative to the housing (2). At least one of the orientation features (34) is located at a rigid part of the cap (3) and at least one of the snap features (34) is located at a less rigid part of the cap (3).

摘要翻译： 药物输送装置（1）包括壳体（2）和可附接到壳体（2）上的盖子（3）。 盖（3）包括一个或多个卡扣特征（33）以将盖（3）附接到壳体（2）上，以及一个或多个取向特征（34）以限定盖（3）相对于壳体 （2）。 取向特征（34）中的至少一个位于盖（3）的刚性部分处，并且卡扣特征（34）中的至少一个位于盖（3）的较刚性部分。

公开(公告)号：US20130197448A1

公开(公告)日：2013-08-01

申请号：US13878464

申请日：2011-10-11

申请人： Joseph Butler ,  David Plumptre

发明人： Joseph Butler ,  David Plumptre

IPC分类号： A61M5/315

CPC分类号： A61M5/31536 ,  A61M5/31525 ,  A61M5/31535 ,  A61M5/31541 ,  A61M5/31551 ,  A61M5/31571 ,  A61M5/3158 ,  A61M5/31593

摘要： A system for preventing delivery of less than a predetermined minimum dose of a medicament by providing a dose setting mechanism having a clutch ring rotationally fixed relative to the housing when a dose less than the minimum allowable dose is selected. The dose setting mechanism also includes a drug delivery device housing and a dose dial component positioned in the housing and rotatable during a dose setting step. A drive sleeve is positioned within the dose dial component, a spindle is positioned within the drive sleeve, and a clutch is positioned between the dose dial component and the drive sleeve. When the dose dial component is rotated to select a dose less than a minimum dose, a clutch ring prevents the drive sleeve from rotating to thereby prevent the selected dose from being administered.

摘要翻译： 一种用于当选择小于最小允许剂量的剂量时，通过提供具有相对于壳体旋转固定的离合器环的剂量调节机构来防止递送小于预定最小剂量的药物的系统。 剂量设定机构还包括药剂输送装置壳体和位于壳体中并可在剂量设定步骤期间旋转的剂量拨号部件。 驱动套筒定位在剂量拨盘部件内，主轴定位在驱动套筒内，并且离合器定位在剂量拨号部件和驱动套筒之间。 当剂量拨号组件旋转以选择小于最小剂量的剂量时，离合器环防止驱动套筒旋转，从而防止施用所选择的剂量。

公开(公告)号：US20120172804A1

公开(公告)日：2012-07-05

申请号：US13254614

申请日：2010-03-24

申请人： David Plumptre

发明人： David Plumptre

IPC分类号： A61M5/315 ,  A61M5/20

CPC分类号： A61M5/14566 ,  A61M5/14244 ,  A61M2005/14268 ,  A61M2005/14506 ,  A61M2005/14573

摘要： A medicament delivery device (1) comprises a housing (2) for holding a medicament cartridge (9), a drive (18, 32) and a drive control means (46, 52). The medicament cartridge (9) has a medicament outlet and a bung (20) able to be driven via a piston rod (12, 14) driven by the drive force of the drive (18, 32) and controlled by the drive control means (46, 52). Additionally, the medicament delivery device (1) comprises a restraining means (38) for applying a restraining force to the piston rod (12, 14), in a direction opposite to the drive force. By varying the restraining force by the drive control means (46, 52) the movement of the bung (20) along the medicament cartridge can be controlled.

摘要翻译： 药物输送装置（1）包括用于保持药剂盒（9）的壳体（2），驱动器（18,32）和驱动控制装置（46,52）。 药剂盒（9）具有药物出口和能够通过由驱动器（18,32）的驱动力驱动并由驱动控制装置控制的活塞杆（12,14）驱动的栓（20） 46，52）。 此外，药物输送装置（1）包括用于沿与驱动力相反的方向向活塞杆（12,14）施加限制力的约束装置（38）。 通过改变驱动控制装置（46,52）的约束力，可以控制栓（20）沿药剂盒的移动。

公开(公告)号：US10406292B2

公开(公告)日：2019-09-10

申请号：US13322829

申请日：2010-05-28

申请人： David Plumptre

发明人： David Plumptre

IPC分类号： A61M5/315

摘要： A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove and a helical spline. The inner housing helical spline guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.

公开(公告)号：US09545483B2

公开(公告)日：2017-01-17

申请号：US12326131

申请日：2008-12-02

申请人： David Plumptre

发明人： David Plumptre

IPC分类号： A61M5/315 ,  A61M5/31 ,  A61M5/24 ,  A61M5/50

CPC分类号： A61M5/31555 ,  A61M5/24 ,  A61M5/3146 ,  A61M5/31541 ,  A61M5/3156 ,  A61M5/31575 ,  A61M5/31585 ,  A61M5/50 ,  A61M2005/3104 ,  A61M2005/31518 ,  A61M2005/3152 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583

摘要： A drive assembly comprises a housing, a drive member moveable for setting a dose and for delivering the dose. A piston rod adapted to be driven by the drive member in the distal direction during movement of the drive member in the distal direction for dose delivery and a restriction member for restricting proximal movement of the piston rod during proximal movement of the drive member by mechanical interaction of the restriction member with a stop feature. The restriction member and stop feature arranged for the piston rod to be moved proximally a first distance during a first movement of the drive member before the restriction member and stop feature interact mechanically. The first distance the piston rod moves proximally during the first movement of the drive member is different than a subsequent distance the piston rod moves during a subsequent proximal movement of the drive member.

摘要翻译： 驱动组件包括壳体，可移动以设定剂量并用于递送剂量的驱动构件。 一种活塞杆，其适于在驱动构件沿远侧方向运动期间在远侧方向上被驱动，用于剂量递送;以及限制构件，用于限制活塞杆在驱动构件的近端运动期间的机械相互作用 具有停止特征的限制构件。 在限制构件和停止特征在机械相互作用之前，在驱动构件的第一移动期间，排列用于活塞杆向近端移动第一距离的限制构件和止挡特征。 活塞杆在驱动构件的第一运动期间向近侧移动的第一距离不同于在驱动构件的随后的近侧运动期间活塞杆移动的随后的距离。

公开(公告)号：US09125993B2

公开(公告)日：2015-09-08

申请号：US13375186

申请日：2010-05-28

申请人： David Plumptre

发明人： David Plumptre

IPC分类号： A61M5/31 ,  A61M5/315

CPC分类号： A61M5/31543 ,  A61M5/31541 ,  A61M5/31551 ,  A61M5/31585 ,  A61M2005/3126 ,  A61M2205/27

摘要： A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.

摘要翻译： 公开了用于药物输送装置的剂量设定机构。 该机构包括外壳和具有外槽的内壳。 内壳引导驾驶员分配一定剂量。 拨号套筒设置在外壳体和内壳体之间并且可旋转地与内壳体接合。 当剂量被设定时，拨盘套筒旋转并且从外壳体和内壳体两者平移。

公开(公告)号：US09089651B2

公开(公告)日：2015-07-28

申请号：US13878464

申请日：2011-10-11

申请人： Joseph Butler ,  David Plumptre

发明人： Joseph Butler ,  David Plumptre

IPC分类号： A61M5/315

CPC分类号： A61M5/31536 ,  A61M5/31525 ,  A61M5/31535 ,  A61M5/31541 ,  A61M5/31551 ,  A61M5/31571 ,  A61M5/3158 ,  A61M5/31593

摘要： A system for preventing delivery of less than a predetermined minimum dose of a medicament by providing a dose setting mechanism having a clutch ring rotationally fixed relative to the housing when a dose less than the minimum allowable dose is selected. The dose setting mechanism also includes a drug delivery device housing and a dose dial component positioned in the housing and rotatable during a dose setting step. A drive sleeve is positioned within the dose dial component, a spindle is positioned within the drive sleeve, and a clutch is positioned between the dose dial component and the drive sleeve. When the dose dial component is rotated to select a dose less than a minimum dose, a clutch ring prevents the drive sleeve from rotating to thereby prevent the selected dose from being administered.

摘要翻译： 一种用于当选择小于最小允许剂量的剂量时，通过提供具有相对于壳体旋转固定的离合器环的剂量调节机构来防止递送小于预定最小剂量的药物的系统。 剂量设定机构还包括药剂输送装置壳体和位于壳体中并可在剂量设定步骤期间旋转的剂量拨号部件。 驱动套筒定位在剂量拨盘部件内，主轴定位在驱动套筒内，并且离合器定位在剂量拨号部件和驱动套筒之间。 当剂量拨号组件旋转以选择小于最小剂量的剂量时，离合器环防止驱动套筒旋转，从而防止施用所选择的剂量。

公开(公告)号：US20120172814A1

公开(公告)日：2012-07-05

申请号：US13375183

申请日：2010-05-28

申请人： David Plumptre ,  Christopher Jones

发明人： David Plumptre ,  Christopher Jones

IPC分类号： A61M5/31

CPC分类号： A61M5/31543 ,  A61M5/31511 ,  A61M5/31541 ,  A61M5/31551 ,  A61M5/31558 ,  A61M5/31575 ,  A61M5/31585 ,  A61M2005/2407 ,  A61M2005/2488 ,  A61M2005/2492 ,  A61M2005/3152

摘要： A driver for driving a spindle of a drug delivery device is provided. Said driver comprises a first component and a second component rotationally coupled to said first component. During resetting of said drug delivery device, said first component is rotationally decoupled from said second component.

摘要翻译： 提供了用于驱动药物输送装置的心轴的驱动器。 所述驱动器包括旋转地耦合到所述第一部件的第一部件和第二部件。 在所述药物递送装置的复位期间，所述第一部件与所述第二部件旋转地分离。

公开(公告)号：US20120165750A1

公开(公告)日：2012-06-28

申请号：US13322829

申请日：2010-05-28

申请人： David Plumptre

发明人： David Plumptre

IPC分类号： A61M5/31

CPC分类号： A61M5/31525 ,  A61M5/31541 ,  A61M5/31543 ,  A61M5/31551 ,  A61M5/31585

摘要： A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove and a helical spline. The inner housing helical spline guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.

摘要翻译： 公开了用于药物输送装置的剂量设定机构。 该机构包括外壳和具有外槽和螺旋花键的内壳。 内壳螺旋花键引导驾驶员分配一定剂量。 拨号套筒设置在外壳体和内壳体之间并且可旋转地与内壳体接合。 当剂量被设定时，拨盘套筒旋转并且从外壳体和内壳体两者平移。

公开(公告)号：US20120165742A1

公开(公告)日：2012-06-28

申请号：US13320634

申请日：2010-05-28

申请人： David Plumptre

发明人： David Plumptre

IPC分类号： A61M5/31

CPC分类号： A61M5/31536 ,  A61M2005/3154

摘要： A method and system for proving a drug delivery device having a variable maximum dose. The drug delivery device comprising a first tubular member and a second tubular member rotatably coupled to the first tubular member. A maximum stop component is operatively coupled to the first tubular member and the second tubular member such that the maximum stop component is movable from a first position to a second position. The first position defines a first maximum dose that may be set by a user of said drug delivery device and the second position defines a second maximum dose that may be set by the user of said drug delivery device.

摘要翻译： 用于证明具有可变最大剂量的药物递送装置的方法和系统。 药物递送装置包括第一管状构件和可旋转地联接到第一管状构件的第二管状构件。 最大限制部件可操作地联接到第一管状部件和第二管状部件，使得最大止挡部件可从第一位置移动到第二位置。 第一位置定义可由所述药物递送装置的使用者设定的第一最大剂量，而第二位置限定可由所述药物递送装置的使用者设定的第二最大剂量。