Drive mechanism for a drug delivery device

    公开(公告)号:US10076610B2

    公开(公告)日:2018-09-18

    申请号:US14782655

    申请日:2014-04-08

    申请人: Sanofi

    IPC分类号: A61M5/315 A61M5/20

    摘要: A drive mechanism for a drug delivery device includes an elongated housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. A drive sleeve is rotatably supported in the housing, operably releasable from the piston rod for setting of a dose, and operably engageable with the piston rod for dispensing of the dose. A dose limiting member is engaged with the drive sleeve and engaged with the piston rod in such a way that it is displaced in axial direction relative to the drive sleeve when the drive sleeve rotates relative to the piston rod during a dose setting procedure. At least one stop is configured to engage with the dose limiting member for limiting the axial displacement of the dose limiting member during the dose setting procedure and to impede further displacement of the drive sleeve relative to the piston rod.

    Dose setting mechanism for an injection device and having a preset feature

    公开(公告)号:US09669168B2

    公开(公告)日:2017-06-06

    申请号:US15147469

    申请日:2016-05-05

    申请人: Novo Nordisk A/S

    IPC分类号: A61M5/315

    摘要: A dose setting mechanism for an injection device having a rotatably operated dose setting member, a presetting member being operable to limit the maximum dose settable by the dose setting member, and a first stopping member is operatively connected to the presetting member where the position of the first stopping member indicates the preset maximum dose. The first stopping member is adapted to rotatably engage with a second stopping member when the preset maximum dose has been set, thereby preventing setting of a further dose. The first and/or the second stopping member is/are movable along with the dose setting member, the first and second stopping members thereby being moved into engagement when a dose is set. Thereby a dose can be preset and the preset dose can easily be repeatedly set while ensuring an accurate dosage. The contemplated device can aid persons being visually impaired or having poor dexterity in setting a correct and accurate dose.

    Pre-loaded syringe with metered dosing and methods of use
    7.
    发明授权
    Pre-loaded syringe with metered dosing and methods of use 有权
    预装注射器,计量剂量和使用方法

    公开(公告)号:US09545481B1

    公开(公告)日:2017-01-17

    申请号:US14213101

    申请日:2014-03-14

    IPC分类号: A61M5/315 A61M5/31

    摘要: Methods and devices for metering and delivering a desired dose of medication from a syringe are described. The devices may include a dosage limiting sleeve adjustably disposed around a syringe body, wherein the alignment of the dosage limiting sleeve relative to the syringe body indicates the dose to be administered by depressing a plunger until the dosage limiting sleeve is engaged.

    摘要翻译: 描述了从注射器计量和递送期望剂量的药物的方法和装置。 装置可以包括可调节地设置在注射器主体周围的剂量限制套筒,其中剂量限制套管相对于注射器主体的对准指示通过按压柱塞直到剂量限制套筒接合来施用的剂量。

    DRUG DELIVERY DEVICE
    8.
    发明申请
    DRUG DELIVERY DEVICE 审中-公开
    药物递送装置

    公开(公告)号:US20160151580A1

    公开(公告)日:2016-06-02

    申请号:US14905393

    申请日:2014-07-17

    申请人: SANOFI

    IPC分类号: A61M5/315

    摘要: The invention refers to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a cartridge holder (20) for receiving a cartridge (170), a lead screw (30) and means (40, 90) for driving the lead screw (30) during dose dispensing. The lead screw (30) is coupled to the cartridge holder (20) such that the cartridge holder (20) is axially displaced with respect to the housing (10) and the lead screw (30) during dose dispensing.

    摘要翻译: 本发明涉及用于选择和分配多个用户可变剂量的药物的药物递送装置。 该装置包括壳体(10),用于容纳盒(170)的盒保持器(20),用于在剂量分配期间驱动丝杠(30)的导螺杆(30)和装置(40,90)。 导螺杆(30)联接到药筒保持器(20),使得药筒保持器(20)在剂量分配期间相对于壳体(10)和丝杠(30)轴向移位。

    AUTOMATIC DRUG INJECTION DEVICE WITH REVERSE WOUND FLAT SPIRAL SPRING DRIVE MECHANISM
    9.
    发明申请
    AUTOMATIC DRUG INJECTION DEVICE WITH REVERSE WOUND FLAT SPIRAL SPRING DRIVE MECHANISM 审中-公开
    具有反转平面螺旋弹簧驱动机构的自动注射装置

    公开(公告)号:US20160082196A1

    公开(公告)日:2016-03-24

    申请号:US14783591

    申请日:2014-04-08

    申请人: SANOFI

    IPC分类号: A61M5/315

    摘要: The present invention relates to a handheld automatic injection device comprising a housing (10, 30, 40; 40′), a piston rod (80) located within the housing (10, 30, 40; 40′), a drive member (70) permanently coupled to the piston rod (80), a dose setting member (50), which during dose setting rotates relative to the housing (10, 30, 40; 40′) in a first direction and which during dose dispensing rotates relative to the housing (10, 30, 40; 40′) in a second opposite direction, and a power reservoir (100) for driving the drive member (70). The drive member (70) is axially movable between a dose setting position, in which the drive member (70) is rotationally constrained to the housing, and a dose dispensing position, in which the drive member (70) is rotationally decoupled from the housing (10, 30, 40; 40′). The power reservoir comprises a reverse wound flat spiral spring (100) having a first end attached to a first spool (101) and a second end attached to a second spool (102), with one of the spools (102) being coupled to the drive member (70).

    摘要翻译: 本发明涉及一种手持式自动注射装置,其包括壳体(10,30,40; 40'),位于壳体(10,30,40,40')内的活塞杆(80),驱动构件(70 ),剂量设定构件(50),其在剂量设定期间相对于所述壳体(10,30,40,40')在第一方向上旋转,并且在剂量分配期间相对于所述活塞杆 所述壳体(10,30,40; 40')处于第二相反方向,以及用于驱动所述驱动构件(70)的动力储存器(100)。 驱动构件(70)可以在驱动构件(70)被旋转地约束到壳体的剂量设定位置和剂量分配位置之间轴向移动,在该剂量设定位置,驱动构件(70)与壳体 (10,30,40,40')。 动力储存器包括反向卷绕的扁平螺旋弹簧(100),其具有附接到第一卷轴(101)的第一端和附接到第二卷轴(102)的第二端,其中一个卷轴(102)联接到 驱动构件(70)。

    PEN-TYPE DRUG INJECTION DEVICE AND DOSE SETTING LIMITER MECHANISM THEREFOR
    10.
    发明申请
    PEN-TYPE DRUG INJECTION DEVICE AND DOSE SETTING LIMITER MECHANISM THEREFOR 审中-公开
    PEN型药物注射装置和剂量设定限制机制

    公开(公告)号:US20160058952A1

    公开(公告)日:2016-03-03

    申请号:US14783457

    申请日:2014-04-08

    申请人: SANOFI

    IPC分类号: A61M5/315 A61M5/20

    摘要: The present invention relates to a pen type drug delivery device having a dose setting limiter mechanism. The mechanism comprises a housing (10, 30, 40; 40′), a dose setting member (50), which during dose setting rotates relative to the housing (10, 30, 40; 40′) in a first direction and which during dose dispensing rotates relative to the housing (10, 30, 40; 40′) in a second opposite direction, and a limiting element (60) limiting the rotational movement of the dose setting member between a zero dose position and a maximum dose position. The limiting element (60) is rotationally constrained but axially displaceable relative to one of the housing (10, 30, 40; 40′) or the dose setting member (50) and is movable helically (53) relative to the other of the housing (10, 30, 40; 40′)or the dose setting member (50). These movements have end stops (54, 55) limiting the relative movement of the limiting element (60) and thus the dose setting member.

    摘要翻译: 本发明涉及具有剂量设定限制机构的笔式药物输送装置。 该机构包括一个剂量设定部件(50),剂量设定部件(50),其在剂量设定期间相对于壳体(10,30,40,40')在第一方向上旋转, 剂量分配在第二相反方向相对于壳体(10,30,40; 40')旋转;以及限制元件(60),其限制剂量设定构件在零剂量位置和最大剂量位置之间的旋转运动。 所述限制元件(60)被旋转地约束,但是相对于所述壳体(10,30,40,40')或所述剂量设定构件(50)中的一个可轴向移动并且相对于所述外壳中的另一个可旋转地移动(53) (10,30,40,40')或剂量设定部件(50)。 这些移动具有限制限制元件(60)的相对运动并因此限制剂量设定构件的止挡件(54,55)。