摘要:
A lampsocket is provided with a body having an extension both of which contain a continuous bore of a first predetermined diameter dimension to prevent the seating and electrical connection of an electrical lamp having a neck dimension in excess of first predetermined dimension to thereby reject inappropriate lamps and only permit the seating and electrical connection of suitable lamps.
摘要:
A lampholder for shrouded low-wattage metal halide lamps which include a contact button on an extension of the lamp base to distinguish them from unshrouded lamps. A hub with walls and top is placed about the entrance to an additional cavity in the lampholder body. A socket contact is arranged to only make contact with the contact button at the end of an extension which is able to enter the cavity and not make contact with a contact button not an extension which is prevented from entering the cavity.
摘要:
A removable locking system for a fluorescent U-tube electrically connected to a mounting body connected to a surface. The mounting body has a flange extending over the coupling member of the connecting end of the U-tube at the mounting body. A locking screw member is threaded through a hole in the flange into pressing contact with the top of the coupling member of the U-tube. A self-locking washer is positioned between the head element of the screw and the top surface of the flange. The locking screw can be rotated to lock or free the U-tube from its mounted association with the mounting body.
摘要:
An adapter for permitting a lamp to be threaded into a light socket while preventing damage to the socket through application of excessive threading force includes a threaded sleeve rotatably mounted on a cylindrical body and conductive securing means for preventing longitudinal movement of the sleeve with respect to the body, the securing means being urged nto sliding electrical contact with the sleeve and being connected to an electrical conductor for maintaining electrical continuity between the sleeve and an energizing terminal of the lamp. A cam on the ring cooperates with an opening in the sleeve for permitting relative rotation between the sleeve and body in one direction when a threshold torque is exceeded to prevent damage to the socket but preventing relative rotation in the other direction so that the lamp and adapter can be threaded out of the socket.
摘要:
A lamp holder of the type used to removably hold a fluorescent lamp in a lighting fixture has a housing in which there are defined channels for inserting pins protruding from the end of the lamp and a tiltable locking member rotatable between an open position permitting the pins to enter the channels and a closed position preventing withdrawal of the pins from the channels. The locking member is held in the closed position by cooperating means on the housing and locking member.
摘要:
In various embodiments, the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to a vertebrate high mobility group box (HMGB) polypeptide, methods of detecting and/or identifying an agent that binds to an HMGB polypeptide, methods of treating a condition in a subject characterized by activation of an inflammatory cytokine cascade and methods of detecting an HMGB polypeptide in a sample.
摘要:
Antibodies and antigen-binding fragments of antibodies that bind human CXCR3 are disclosed. In preferred embodiments, the antibodies are human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods which employ the antibodies and antigen-binding fragments.
摘要:
Antibodies and antigen-binding fragments of antibodies that bind human CXCR3 are disclosed. In preferred embodiments, the antibodies are human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods which employ the antibodies and antigen-binding fragments.
摘要:
Compositions and methods are disclosed for treating a condition characterized by activation of an inflammatory cytokine cascade in a patient. The compositions comprise an HMGB A box and an inhibitor of complement biological activity, and/or an antibody that binds an HMGB polypeptide or biologically active fragment thereof and an inhibitor of complement biological activity, and/or an inhibitor of HMGB receptor binding and an inhibitor of complement biological activity. The methods comprise treating a cell or a patient with sufficient amounts of the composition to inhibit the release of proinflammatory cytokine(s) and/or inhibit the inflammatory cytokine cascade.
摘要:
In various embodiments, the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to a vertebrate high mobility group box (HMGB) polypeptide, methods of detecting and/or identifying an agent that binds to an HMGB polypeptide, methods of treating a condition in a subject characterized by activation of an inflammatory cytokine cascade and methods of detecting an HMGB polypeptide in a sample.