利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

72 条记录 (耗时 0.039 秒)

    Techniques for inspecting an electronic device
    51.
    发明申请
    Techniques for inspecting an electronic device 审中-公开
    检查电子设备的技术

    公开(公告)号：US20070202476A1

    公开(公告)日：2007-08-30

    申请号：US11347435

    申请日：2006-02-03

    申请人： Mark Williamson

    发明人： Mark Williamson

    IPC分类号： G09B19/00

    CPC分类号： G01N21/95607 ,  G01N2021/8822 ,  G01N2021/8854

    摘要： A novel method of classifying physical structures on a substrate. In certain embodiments, the method includes receiving a perceived image of a substrate, and classifying a physical structure on the substrate by comparing the perceived image to a simulated image. The perceived image may be received from a RDA tool, and the simulated image may be generated by software that models the effect of a candidate structure, i.e., a simulated physical structure, on radiation of the sort used to obtain the perceived image. Comparing the perceived image to the simulated image may include comparing the perceived image to a library of simulated images or analyzing the perceived image with a simplified model that is based on simulated images. By comparing the perceived image of an unknown physical structure to a simulated image of a known candidate structure, the unknown physical structure may be classified.

    摘要翻译： 一种将基底物理结构分类的新方法。 在某些实施例中，该方法包括接收基底的感知图像，以及通过将感知到的图像与模拟图像进行比较来对基底上的物理结构进行分类。 可以从RDA工具接收所感知的图像，并且可以由对用于获得感知图像的排序的辐射对候选结构（即，模拟物理结构）的影响进行建模的软件生成模拟图像。 将感知到的图像与模拟图像进行比较可以包括将感知图像与模拟图像库进行比较，或者使用基于模拟图像的简化模型分析感知图像。 通过将未知物理结构的感知图像与已知候选结构的模拟图像进行比较，可以对未知的物理结构进行分类。

    Methods and compositions for treating cancer using 2192, 2193, 6568, 8895, 9138, 9217, 9609, 9857, 9882, 10025, 20657, 21163, 25848, 25968, 32603, 32670, 33794, 54476 and 94710
    52.
    发明申请
    Methods and compositions for treating cancer using 2192, 2193, 6568, 8895, 9138, 9217, 9609, 9857, 9882, 10025, 20657, 21163, 25848, 25968, 32603, 32670, 33794, 54476 and 94710 审中-公开
    用于治疗癌症的方法和组合物，使用2192,2133,6568,8895,9138,9217,9609,9857,9882,10025,20657,21163,25848,25968,32603,32670,33794,5446和94710

    公开(公告)号：US20070087375A1

    公开(公告)日：2007-04-19

    申请号：US11633986

    申请日：2006-12-05

    申请人： John Hunter ,  Mark Williamson ,  Kyle MacBeth ,  Laura Rudolph-Owen ,  Fong-Ying Tsai

    发明人： John Hunter ,  Mark Williamson ,  Kyle MacBeth ,  Laura Rudolph-Owen ,  Fong-Ying Tsai

    IPC分类号： C12Q1/68 ,  G01N33/574

    CPC分类号： G01N33/5011 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N2500/04 ,  G01N2500/10

    摘要： The present invention relates to methods for the diagnosis and treatment of a cancer or cancer. Specifically, the present invention identifies the differential expression of 2192, 2193, 6568, 8895, 9138, 9217, 9609, 9857, 9882, 10025, 20657, 21163, 25848, 25968, 32603, 32670, 33794, 54476 and 94710 genes in tissues relating to cancer, relative to their expression in normal, or non-cancer disease states, and/or in response to manipulations relevant to a cancer. The present invention describes methods for the diagnostic evaluation and prognosis of various cancers, and for the identification of subjects exhibiting a predisposition to such conditions. The invention also provides methods for identifying a compound capable of modulating a cancer or cancer. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of cancer.

    摘要翻译： 本发明涉及癌症或癌症的诊断和治疗方法。 具体而言，本发明鉴定组织中的2192,2133,6568,8895,9138,9217,9609,9857,9882,10025,20657,21163,25848,25968,32603,32670,3797,45476和94710基因的差异表达 涉及癌症，相对于它们在正常或非癌症疾病状态中的表达，和/或响应于与癌症相关的操作。 本发明描述了各种癌症的诊断评估和预后的方法，以及用于鉴定表现出这种病症倾向的受试者。 本发明还提供了鉴定能够调节癌症或癌症的化合物的方法。 本发明还提供了鉴定和治疗化合物作为癌症治疗的方法。

    Portable personal property protector
    54.
    发明授权
    Portable personal property protector 失效
    便携式个人财产保护者

    公开(公告)号：US5162778A

    公开(公告)日：1992-11-10

    申请号：US684971

    申请日：1991-04-15

    申请人： Mark Williamson

    发明人： Mark Williamson

    IPC分类号： G08B13/14

    CPC分类号： G08B13/1436

    摘要： A portable anti-theft device has a gravity operated switch, settable manually or by action of gravity to an open position. This switch is connected in series with a key switch and an alarm, to provide an alarm when the gravity operated switch is moved. The gravity operated switch may be a mercury switch. The gravity operated switch may be pendularly mounted, and be restrained from movement by operation of the key switch.

    摘要翻译： 便携式防盗装置具有重力操作的开关，可手动设置或通过重力作用到打开位置。 该开关与钥匙开关和报警器串联连接，以便在重力操作开关移动时提供报警。 重力操作的开关可以是水银开关。 重力操作开关可以是摆式安装的，并且通过钥匙开关的操作来限制运动。

    Communication network data manager system
    55.
    发明授权
    Communication network data manager system 失效
    通信网络数据管理系统

    公开(公告)号：US5146561A

    公开(公告)日：1992-09-08

    申请号：US203874

    申请日：1988-06-02

    申请人： Paul J. Carey ,  Thomas R. Imburgia ,  John L. Edgar ,  Denis C. McHugh ,  Lan P. Tam ,  Douglas Chieng ,  Mark Williamson

    发明人： Paul J. Carey ,  Thomas R. Imburgia ,  John L. Edgar ,  Denis C. McHugh ,  Lan P. Tam ,  Douglas Chieng ,  Mark Williamson

    IPC分类号： H04L29/00 ,  H04L29/06

    CPC分类号： H04L29/06 ,  H04L29/00 ,  Y10S707/99953

    摘要： The communication network data manager system according to the invention provides remotely located host processors with the capability of moving sequential datasets, partitioned datasets, or members of partitioned datasets between them. Data is read directly from the source dataset, which may be on a tape or disk, and is written directly to the target dataset which also may be on a tape or disk. No intermediate storage is required for queuing or spooling the data being transferred. A data transfer request may be entered by the user through a user console operating under a menu driven display format. Alternatively, the data set transfer request may be generated by continuously running job applications through a batch interface.

    摘要翻译： 根据本发明的通信网络数据管理系统为远程位置的主机处理器提供移动顺序数据集，分区数据集或它们之间的分区数据集成员的能力。 数据直接从源数据集中读取，数据集可能位于磁带或磁盘上，并直接写入目标数据集，也可能在磁带或磁盘上。 不需要中间存储来排队或假脱机正在传输的数据。 数据传输请求可以由用户通过在菜单驱动显示格式下操作的用户控制台输入。 或者，数据集传送请求可以通过批处理接口连续运行作业应用来生成。

    17867, a novel human aminopeptidase
    56.
    发明授权
    17867, a novel human aminopeptidase 失效
    17867，一种新型人氨基肽酶

    公开(公告)号：US07977059B2

    公开(公告)日：2011-07-12

    申请号：US12129509

    申请日：2008-05-29

    申请人： Rosana Kapeller-Libermann ,  Mark Williamson

    发明人： Rosana Kapeller-Libermann ,  Mark Williamson

    IPC分类号： C12Q1/00 ,  G01N33/00 ,  G01N33/53 ,  G01N33/567 ,  G01N33/573

    CPC分类号： C12Q1/37 ,  A61K38/00 ,  C12N9/48 ,  G01N2500/00 ,  Y02A50/475

    摘要： The present invention relates to a newly identified human aminopeptidase. The invention also relates to polynucleotides encoding the aminopeptidase. The invention further relates to methods using the aminopeptidase polypeptides and polynucleotides as a target for diagnosis and treatment in aminopeptidase-related disorders. The invention further relates to drug-screening methods using the aminopeptidase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the aminopeptidase polypeptides and polynucleotides. The invention further relates to procedures for producing the aminopeptidase polypeptides and polynucleotides.

    摘要翻译： 本发明涉及新鉴定的人类氨基肽酶。 本发明还涉及编码氨基肽酶的多核苷酸。 本发明还涉及使用氨基肽酶多肽和多核苷酸作为在氨基肽酶相关疾病中进行诊断和治疗的靶标的方法。 本发明还涉及使用氨基肽酶多肽和多核苷酸鉴定用于诊断和治疗的激动剂和拮抗剂的药物筛选方法。 本发明还包括基于氨基肽酶多肽和多核苷酸的激动剂和拮抗剂。 本发明还涉及生产氨基肽酶多肽和多核苷酸的方法。

    Integrated circuit chips, apparatuses for obtaining backscatter data from samples, methods of backscatter analysis, and methods of forming alpha particle emission and detection systems
    57.
    发明授权
    Integrated circuit chips, apparatuses for obtaining backscatter data from samples, methods of backscatter analysis, and methods of forming alpha particle emission and detection systems 失效
    集成电路芯片，用于从样本获得反向散射数据的装置，反向散射分析的方法和形成α粒子发射和检测系统的方法

    公开(公告)号：US07557345B2

    公开(公告)日：2009-07-07

    申请号：US11787852

    申请日：2007-04-18

    申请人： Mark Williamson ,  Gurtej S. Sandhu

    发明人： Mark Williamson ,  Gurtej S. Sandhu

    IPC分类号： G01N23/00

    CPC分类号： H01L31/115

    摘要： Some embodiments include methods for fabricating an alpha particle emitter and detector associated with an integrated circuit chip. Some embodiments include an integrated circuit chip comprising an alpha particle emitter and detector supported by a semiconductor substrate. Some embodiments include an apparatus for obtaining backscatter data from a sample utilizing an alpha particle emission and detection system supported by a semiconductor substrate. Some embodiments include methods of backscatter analysis utilizing a semiconductor substrate containing an alpha particle emitter and an alpha particle sensor.

    摘要翻译： 一些实施例包括用于制造与集成电路芯片相关联的α粒子发射器和检测器的方法。 一些实施例包括集成电路芯片，其包括由半导体衬底支撑的α粒子发射器和检测器。 一些实施例包括用于利用由半导体衬底支持的α粒子发射和检测系统从样本获得反向散射数据的装置。 一些实施例包括使用含有α粒子发射器和α粒子传感器的半导体衬底的后向散射分析的方法。

    MDA-9 and uses thereof
    59.
    发明授权
    MDA-9 and uses thereof 失效
    MDA-9及其用途

    公开(公告)号：US06866993B1

    公开(公告)日：2005-03-15

    申请号：US09531369

    申请日：2000-03-21

    申请人： Mark Williamson

    发明人： Mark Williamson

    IPC分类号： C12Q1/68 ,  G01N33/574 ,  C12Q1/00 ,  G01N33/53

    CPC分类号： C12Q1/6883 ,  C12Q2600/158 ,  G01N33/574 ,  G01N2800/44

    摘要： Increased expression of MDA-9 is associated with drug resistance of certain cells (e.g., cancer cells). The invention provides methods for identifying drug resistant cells by measuring the expression or activity of MDA-9, methods for identifying modulators of drug resistance, and methods for modulating drug resistance by modulating the expression or activity of MDA-9.

    摘要翻译： MDA-9的增加的表达与某些细胞（例如癌细胞）的耐药性相关。 本发明提供了通过测量MD​​A-9的表达或活性，鉴定药物抗性调节剂的方法和通过调节MDA-9的表达或活性来调节药物抗性的方法来鉴定耐药性细胞的方法。