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70 条记录 (耗时 0.095 秒)

    Confectionery delivery system for expectorants
    51.
    发明授权
    Confectionery delivery system for expectorants 失效
    祛痰糖果交付系统

    公开(公告)号：US4882156A

    公开(公告)日：1989-11-21

    申请号：US258248

    申请日：1988-10-14

    申请人： Robert K. Yang ,  Shri C. Sharma ,  Shan-Shan Sheu ,  James J. Shaw

    发明人： Robert K. Yang ,  Shri C. Sharma ,  Shan-Shan Sheu ,  James J. Shaw

    IPC分类号： A61K9/00 ,  A61K9/16 ,  A61K9/50

    CPC分类号： A61K9/5015 ,  A61K9/0056 ,  A61K9/1617 ,  Y10S514/948 ,  Y10S514/96

    摘要： A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.

    摘要翻译： 一种用于活性物质的可咀嚼递送系统，包括：（a）预先涂覆有至少一种选自卵磷脂，链长度为约4个碳以下的聚氧化烯，熔点为100℃的甘油酯的材料的活性物质。 或更少的分子量为3,700以下的聚亚烷基二醇，合成和天然蜡及其混合物; 和（b）糖果基质，其包含包含明胶和选自甘油及其低级烷基（C2-7）酯衍生物）的保湿剂材料的粘合剂体系; 甜味剂 和约1％至约30％重量的水。

    Confectionery delivery system for antihistimines
    52.
    发明授权
    Confectionery delivery system for antihistimines 失效
    抗组织药物的糖果交付系统

    公开(公告)号：US4882151A

    公开(公告)日：1989-11-21

    申请号：US258284

    申请日：1988-10-14

    申请人： Robert K. Yang ,  Shri C. Sharma ,  Shan-Shan Sheu ,  James J. Shaw

    发明人： Robert K. Yang ,  Shri C. Sharma ,  Shan-Shan Sheu ,  James J. Shaw

    IPC分类号： A61K9/00 ,  A61K9/16 ,  A61K9/50

    CPC分类号： A61K9/1617 ,  A61K9/0056 ,  A61K9/5015 ,  Y10S514/948 ,  Y10S514/96

    摘要： A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lenghts of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant maerial selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.

    摘要翻译： 一种用于活性物质的可咀嚼递送系统，包括：（a）预先涂覆有至少一种选自卵磷脂，具有约4个碳以下的链长度的聚氧化烯，熔点为100℃的甘油酯的材料的活性物质。 或更少的分子量为3,700以下的聚亚烷基二醇，合成和天然蜡及其混合物; 和（b）糖果基质，其包含包含明胶和选自甘油及其低级烷基（C2-7）酯衍生物）的保湿剂的粘合剂体系; 甜味剂 和约1％至约30％重量的水。

    Novel sweetener delivery systems
    53.
    发明授权
    Novel sweetener delivery systems 失效
    新型甜味剂输送系统

    公开(公告)号：US4752485A

    公开(公告)日：1988-06-21

    申请号：US658101

    申请日：1984-10-05

    申请人： Shri C. Sharma ,  Robert K. Yang ,  James J. Shaw

    发明人： Shri C. Sharma ,  Robert K. Yang ,  James J. Shaw

    IPC分类号： A23L27/00 ,  A23L27/30 ,  A61K9/16 ,  A61K9/68 ,  A61K47/06 ,  A61K47/12 ,  A61K47/22 ,  A61K47/26 ,  A61K47/42 ,  A23L1/22 ,  A23L1/236 ,  A23L3/30

    CPC分类号： A61K9/1617 ,  A23V2002/00 ,  Y10S426/804

    摘要： The present inventive compositions concern a stable delivery system capable of effecting a controlled release of core material comprising:(A) at least one natural or artificial core material selected from the group consisting of amino acid based sweeteners, dipeptide sweeteners, glycyrrhizin, saccharin and its salts, acesulfame salts, cyclamates, steviosides, talin, dihyrochalcone compounds, drugs, medicaments, flavoring agents and mixtures thereof; and(B) a hydrophobic matrix consisting essentially of(i) lecithin; and(ii) an edible material having a melting point in the range of about 25.degree. C. to about 100.degree. C. selected from the group consisting of (a) fatty acids having an iodine value of about 1 to about 10, (b) natural waxes, (c) synthetic waxes and (d) mixtures thereof; and(iii) at least one glyceride.

    摘要翻译： 本发明的组合物涉及能够实现核心材料的受控释放的稳定的递送系统，其包含：（A）至少一种选自氨基酸的甜味剂，二肽甜味剂，甘草甜素，糖精及其它的天然或人造核心材料 盐，乙酰磺胺酸盐，环磷酰胺，甜菊苷，talin，二氢查耳酮化合物，药物，药物，调味剂及其混合物; 和（B）基本上由（i）卵磷脂组成的疏水性基质; 和（ii）熔点在约25℃至约100℃范围内的可食用材料，其选自（a）碘值为约1至约10的脂肪酸，（b ）天然蜡，（c）合成蜡和（d）它们的混合物; 和（iii）至少一种甘油酯。

    Polyethylene-oxide based films and drug delivery systems made therefrom
    54.
    发明授权
    Polyethylene-oxide based films and drug delivery systems made therefrom 无效
    聚乙烯氧化物基膜和由其制成的药物递送系统

    公开(公告)号：US07897080B2

    公开(公告)日：2011-03-01

    申请号：US12614928

    申请日：2009-11-09

    申请人： Robert K. Yang ,  Richard C. Fuisz ,  Gary L. Myers ,  Joseph M. Fuisz

    发明人： Robert K. Yang ,  Richard C. Fuisz ,  Gary L. Myers ,  Joseph M. Fuisz

    IPC分类号： B29C39/14

    CPC分类号： A61K8/731 ,  A61K8/0216 ,  A61K8/86 ,  A61K9/006 ,  A61K9/7007 ,  A61K9/7015 ,  A61K2800/92 ,  A61Q11/00 ,  C08J5/18 ,  C08J2371/02 ,  F26B13/104

    摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.

    摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分，其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地，膜还含有药物和/或化妆品活性剂，其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10％。

    System for testing properties of materials
    57.
    发明授权
    System for testing properties of materials 失效
    材料性能测试系统

    公开(公告)号：US06474140B2

    公开(公告)日：2002-11-05

    申请号：US09813056

    申请日：2001-03-19

    申请人： Chi-Neng Arthur Han ,  Robert K. Yang ,  Alex J. Phinn

    发明人： Chi-Neng Arthur Han ,  Robert K. Yang ,  Alex J. Phinn

    IPC分类号： G01N3300

    CPC分类号： G01N33/346

    摘要： A system including methods and apparatus for measuring properties of a material, such as surface tension, surface energy, absorption, adsorption, permeability, porosity and printability and the like. A chemical marker containing test liquid is applied to the material and excess test liquid not retained by the material is removed. Thereafter, either the removed test liquid or the test liquid retained by the material is analyzed to determine the amount of chemical marker substance in the test liquid and, thus, the desired property of the material.

    摘要翻译： 包括用于测量材料的性质的方法和装置的系统，例如表面张力，表面能，吸收，吸附，渗透性，孔隙率和可印刷性等。 将含有测试液体的化学标记物施加到材料上，并且除去不被材料保留的过量测试液体。 此后，分析由该材料保留的去除的测试液体或测试液体，以确定测试液体中化学标记物质的量，从而确定材料的所需性质。

    Liquiflash particles and method of making same
    58.
    发明授权
    Liquiflash particles and method of making same 失效
    Liquiflash颗粒及其制备方法

    公开(公告)号：US5849223A

    公开(公告)日：1998-12-15

    申请号：US453053

    申请日：1995-05-26

    申请人： Garry L. Myers ,  Robert K. Yang ,  Mark R. Herman

    发明人： Garry L. Myers ,  Robert K. Yang ,  Mark R. Herman

    IPC分类号： A61J3/02 ,  A61J1/00 ,  A61J7/00 ,  A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/50 ,  B01J2/00 ,  B01J2/02 ,  A61K9/14

    CPC分类号： A61J7/0015 ,  A61J1/00 ,  A61K9/1688 ,  A61K9/1694 ,  A61K9/2081 ,  A61K9/2095 ,  A61K9/5026 ,  B01J2/00 ,  B01J2/02

    摘要： The present invention is a method of making discrete particles by subjecting an organic feedstock to liquiflash conditions whereby the feedstock is transformed instantaneously from solid to liquiform to solid. Liquiform is a transient condition wherein the feedstock has substantially unimpeded internal flow. Shear force is imparted to the liquiform feedstock in an amount sufficient to separate tiny masses of feedstock. The tiny masses solidify as discretized particles. The present invention also includes unique products resulting from the process, e.g., a monodispersed microsphere product and coated particles prepared therefrom.

    摘要翻译： 本发明是通过使有机原料经历液化条件来制备离散颗粒的方法，由此原料从固体瞬间转变成液态至固体。 液体是一种瞬态条件，其中原料具有基本上无阻碍的内部流动。 剪切力被赋予液体原料，其量足以分离出微量的原料。 微小的团块固化为离散粒子。 本发明还包括由该方法产生的独特产物，例如单分散的微球产物和由其制备的包衣颗粒。

    Encapsulation composition for use with chewing gum and edible products
    59.
    发明授权
    Encapsulation composition for use with chewing gum and edible products 失效
    用于口香糖和食用产品的包封组合物

    公开(公告)号：US4929447A

    公开(公告)日：1990-05-29

    申请号：US67894

    申请日：1987-06-29

    申请人： Robert K. Yang

    发明人： Robert K. Yang

    IPC分类号： A23G4/00 ,  A23G4/02 ,  A23G4/06 ,  A23G4/20

    CPC分类号： A23G4/06 ,  A23G4/02 ,  A23G4/20 ,  A23V2002/00

    摘要： The present invention is method and composition for protecting an active ingredient and providing controlled release therefor, especially in a chewing gum composition, which includes a high molecular weight polyvinyl acetate blended with a hydrophobic plasticizer which forms a film with the high molecular weight polyvinyl acetate in the absence of an added solvent therefor. The active ingredient, such as the artificial sweetener aspartame, is blended into the encapsulating composition as, for example, by melt blend which can then be cooled to a solid and ground into particulate. The encapsulated active ingredient can then be used in a composition for ingestion by a human in the form of, for example, a chewing gum with extended shelf life and highly controlled release of the active ingredient.

    摘要翻译： 本发明是用于保护活性成分并提供控制释放的方法和组合物，特别是在口香糖组合物中，其包括与疏水增塑剂共混的高分子量聚乙酸乙烯酯，该疏水增塑剂与高分子量聚乙酸乙烯酯形成膜 没有添加溶剂。 将活性成分，例如人造甜味剂阿斯巴甜，以例如熔融共混物的形式混合到包封组合物中，然后可以将其冷却至固体并研磨成颗粒。 然后将包封的活性成分用于人体摄取的组合物中，例如具有延长的保质期和高度控制的活性成分释放的口香糖的形式。