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1.发明授权Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom 有权具有非自聚集均匀异质性的薄膜和由其制备的药物递送系统公开(公告)号：US07425292B2
公开(公告)日：2008-09-16
申请号：US10074272
申请日：2002-02-14
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/1635 , A61K9/1652 , A61K9/7015 , A61K31/192 , A61K31/422 , A61K31/435 , A61K31/4525 , A61K31/4545 , A61K31/80 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/38 , A61K47/44 , A61K47/46 , C08J5/18
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 理想地，膜在水中分解，并且可以通过受控的干燥过程或保持膜所需均匀性的其它方法形成。
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2.发明申请THIN FILM WITH NON-SELF-AGGREGATING UNIFORM HETEROGENEITY AND DRUG DELIVERY SYSTEMS MADE THEREFROM 审中-公开具有非自我聚集均匀异质性和药物输送系统的薄膜公开(公告)号：US20110182969A1
公开(公告)日：2011-07-28
申请号：US13052655
申请日：2011-03-21
CPC分类号： A61J3/00 , A61K9/006 , A61K9/7007 , B29C48/08 , B29C48/91 , B29C48/919 , F26B13/10 , F26B13/104
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
摘要翻译： 本发明涉及含有所需水平的活性成分的薄膜产品及其制备方法。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 期望地，膜可以暴露于高于活性组分通常降解的温度，而不考虑所需活性的损失。
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公开(公告)号：US07357891B2
公开(公告)日：2008-04-15
申请号：US10768809
申请日：2004-01-30
IPC分类号： B29C47/88
CPC分类号： A61J3/00 , A61K9/006 , A61K9/7007 , B29C47/0021 , B29C47/8805 , B29C47/8895 , F26B13/10 , F26B13/104
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
摘要翻译： 本发明涉及含有所需水平的活性成分的薄膜产品及其制备方法。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 期望地，膜可以暴露于高于活性组分通常降解的温度，而不考虑所需活性的损失。
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公开(公告)号：US07666337B2
公开(公告)日：2010-02-23
申请号：US10856176
申请日：2004-05-28
IPC分类号： B29C39/14
CPC分类号： A61K8/731 , A61K8/0216 , A61K8/86 , A61K9/006 , A61K9/7007 , A61K9/7015 , A61K2800/92 , A61Q11/00 , C08J5/18 , C08J2371/02 , F26B13/104
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分，其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地，膜还含有药物和/或化妆品活性剂，其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10％。
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公开(公告)号：US20080260809A1
公开(公告)日：2008-10-23
申请号：US12107389
申请日：2008-04-22
IPC分类号： A61K9/70
CPC分类号： A61K8/731 , A61K8/0216 , A61K8/86 , A61K9/006 , A61K9/7007 , A61K9/7015 , A61K2800/92 , A61Q11/00 , C08J5/18 , C08J2371/02 , F26B13/104
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分，其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地，膜还含有药物和/或化妆品活性剂，其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10％。
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6.发明授权公开(公告)号：US07897080B2
公开(公告)日：2011-03-01
申请号：US12614928
申请日：2009-11-09
IPC分类号： B29C39/14
CPC分类号： A61K8/731 , A61K8/0216 , A61K8/86 , A61K9/006 , A61K9/7007 , A61K9/7015 , A61K2800/92 , A61Q11/00 , C08J5/18 , C08J2371/02 , F26B13/104
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分，其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地，膜还含有药物和/或化妆品活性剂，其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10％。
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7.发明申请THIN FILM WITH NON-SELF-AGGREGATING UNIFORM HETEROGENEITY AND DRUG DELIVERY SYSTEMS MADE THEREFROM 有权具有非自我聚集均匀异质性和药物输送系统的薄膜公开(公告)号：US20090181069A1
公开(公告)日：2009-07-16
申请号：US12411505
申请日：2009-03-26
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/1635 , A61K9/1652 , A61K9/7015 , A61K31/192 , A61K31/422 , A61K31/435 , A61K31/4525 , A61K31/4545 , A61K31/80 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/38 , A61K47/44 , A61K47/46 , C08J5/18
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 理想地，膜在水中分解，并且可以通过受控的干燥过程或保持膜所需均匀性的其它方法形成。
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8.发明申请公开(公告)号：US20080268027A1
公开(公告)日：2008-10-30
申请号：US12171692
申请日：2008-07-11
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/1635 , A61K9/1652 , A61K9/7015 , A61K31/192 , A61K31/422 , A61K31/435 , A61K31/4525 , A61K31/4545 , A61K31/80 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/38 , A61K47/44 , A61K47/46 , C08J5/18
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film.
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9.发明授权Uniform films for rapid dissolve dosage form incorporating taste-masking compositions 有权包含掩味组合物的快速溶解剂型的均匀膜公开(公告)号：US08603514B2
公开(公告)日：2013-12-10
申请号：US11775484
申请日：2007-07-10
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/14 , A61K9/501 , A61K9/5015 , A61K9/5026 , A61K9/5036 , A61K9/5047 , A61K9/7015 , A61K31/138 , A61K31/192 , A61K31/422 , A61K31/44 , A61K31/4422 , A61K31/443 , A61K31/4545 , A61K31/519 , A61K31/549 , A61K31/567 , A61K31/635 , A61K31/704 , A61K31/7048 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/44 , A61K47/46 , B05D3/0254 , B29C47/0004
摘要： The present invention relates to rapid dissolve thin film drug delivery compositions for the oral administration of active components. The active components are provided as taste-masked or controlled-release coated particles uniformly distributed throughout the film composition. The compositions may be formed by wet casting methods, where the film is cast and controllably dried, or alternatively by an extrusion method.
摘要翻译： 本发明涉及用于口服给药活性成分的快速溶解薄膜药物递送组合物。 活性组分作为均匀分布在整个膜组合物中的掩味或控释包衣颗粒提供。 组合物可以通过湿法铸造方法形成，其中膜被浇铸并可控制地干燥，或者通过挤出方法形成。
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10.发明申请公开(公告)号：US20110278763A1
公开(公告)日：2011-11-17
申请号：US13035328
申请日：2011-02-25
IPC分类号： B29C39/02
CPC分类号： A61K8/731 , A61K8/0216 , A61K8/86 , A61K9/006 , A61K9/7007 , A61K9/7015 , A61K2800/92 , A61Q11/00 , C08J5/18 , C08J2371/02 , F26B13/104
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分，其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 理想地，该膜还含有每单位面积膜的活性剂药物和/或化妆品活性剂不超过10％的药物和/或化妆品活性剂。
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