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111 条记录 (耗时 0.023 秒)

    Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity
    51.
    发明授权
    Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity 失效
    糖酯衍生物，水解酶活性测定试剂和水解酶活性测定方法

    公开(公告)号：US6162614A

    公开(公告)日：2000-12-19

    申请号：US975167

    申请日：1992-11-12

    申请人： Toshio Kurihara ,  Toshiyuki Nishio ,  Hisao Yamamoto ,  Minoru Kamimura ,  Shinichi Teshima ,  Tsuneo Hanyu ,  Shigenori Emi

    发明人： Toshio Kurihara ,  Toshiyuki Nishio ,  Hisao Yamamoto ,  Minoru Kamimura ,  Shinichi Teshima ,  Tsuneo Hanyu ,  Shigenori Emi

    IPC分类号： C07H15/203 ,  C12Q1/34 ,  C12Q1/44

    CPC分类号： C07H15/203 ,  C12Q1/34 ,  C12Q1/44 ,  C12Q2334/00 ,  C12Q2334/10

    摘要： A sugar ester derivative of the general formula (I) ##STR1## wherein G stands for a group of the formula (A) ##STR2## or a group of the formula (B) ##STR3## wherein .lambda. means 0 or 1; at least one of R.sub.1 and R.sub.2 means an ester residue of a saturated or unsaturated fatty acid having 1-30 carbon atoms and the other group means hydrogen atom or acetyl group, and R.sub.3 means a group of the formula (C) ##STR4## wherein X means a halogen atom, m means an integer of 0 to 4, Y means hydroxy group, an alkoxy group, a carboxyl group or sulfonic acid group, n means 0 or 1 and Z means nitro group or nitrovinyl group and its use.The sugar ester derivative of the general formula (I) is useful as a substrate for the measurement of lipase or esterase activities, and the reagents and the methods for measuring lipase or esterase activities which comprise said sugar ester derivative as the substrate are excellent in terms of reproducibility and sensitivity and enable the measurement of lipase or esterase activities in accordance with rate-assay method by an easy procedure.

    摘要翻译： 通式（I）的糖酯衍生物，其中G表示式（A）的基团或式（B）的基团，其中λ表示0或1; R 1和R 2中的至少一个表示具有1-30个碳原子的饱和或不饱和脂肪酸的酯残基，另一个基团是指氢原子或乙酰基，R 3表示式（C）的基团，其中X表示 卤素原子，m表示0〜4的整数，Y表示羟基，烷氧基，羧基或磺酸基，n表示0或1，Z表示硝基或硝基乙烯基及其用途。 通式（I）的糖酯衍生物可用作测定脂肪酶或酯酶活性的底物，并且包含所述糖酯衍生物作为底物的试剂和测定脂肪酶或酯酶活性的方法是优异的 的重现性和灵敏度，并且能够通过简单的方法根据速率测定方法测量脂肪酶或酯酶活性。

    Antiviral agent
    53.
    发明授权
    Antiviral agent 失效
    抗病毒剂

    公开(公告)号：US4174407A

    公开(公告)日：1979-11-13

    申请号：US869144

    申请日：1978-01-13

    申请人： Masaru Fukui ,  Shigeo Ogino ,  Hisao Yamamoto

    发明人： Masaru Fukui ,  Shigeo Ogino ,  Hisao Yamamoto

    IPC分类号： A61K31/13

    CPC分类号： A61K31/13

    摘要： Viral infections caused by viruses belonging to Herpes and Influenza groups can be controlled by administering an effective amount of 3-amino-4-homoisotwistane of the formula, ##STR1##

    摘要翻译： 可以通过施用有效量的下式的3-氨基-4-异亮氨酸来控制属于疱疹和流感组的病毒引起的病毒感染

    Preparation of 2-benzoylalkylbenzomorphan
    54.
    发明授权
    Preparation of 2-benzoylalkylbenzomorphan 失效
    2-苯甲酰基烷基苯并咪唑的制备

    公开(公告)号：US3953441A

    公开(公告)日：1976-04-27

    申请号：US150841

    申请日：1971-06-07

    申请人： Toshio Atsumi ,  Kenji Kobayashi ,  Yoshiaki Takebayashi ,  Hisao Yamamoto

    发明人： Toshio Atsumi ,  Kenji Kobayashi ,  Yoshiaki Takebayashi ,  Hisao Yamamoto

    IPC分类号： C07D211/70 ,  C07D221/26

    CPC分类号： C07D221/26 ,  C07D211/70

    摘要： A novel process for preparing 2-benzoylalkylbenzomorphan derivatives and salts thereof, represented by the formula ##SPC1##Wherein n, R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the specification. The process comprises reacting a pyridinium derivative of the formula, ##SPC2##Wherein X is a halogen atom and Y' is an ethylenedioxy group; with a Grignard reagent of the formula, ##SPC3##Wherein R' is a hydrogen atom or a C.sub.1 -C.sub.3 alkoxy group and Z is a halogen atom, to yield a 1,2-dihydropyridine derivative of the formula; ##SPC4##And then reducing the said 1,2-dihydropyridine derivative to give a 1,2,5,6-tetrahydropyridine derivative of the formula, ##SPC5##Wherein Y is an oxygen atom or an ethylenedioxy group, and further cyclizing the obtained 1,2,5,6-tetrahydropyridine derivative.

    摘要翻译： 由式WHEREIN N，R，R1，R2，R3和R4表示的用于制备2-苯甲酰基烷基苯并喃衍生物及其盐的新方法如本说明书中所定义。 该方法包括使下式的吡啶鎓衍生物WHEREIN X是卤素原子，Y'是亚乙二氧基; 与下式的格利雅试剂，其中R'是氢原子或C1-C3烷氧基，Z是卤素原子，得到下式的1,2-二氢吡啶衍生物; 然后减少所得的1,2-二氢吡啶衍生物，得到本发明的1,2,5,6-四氢吡啶衍生物，其中Y是氧原子或亚乙二氧基，进一步环化得到的1,2,5,6-四氢吡啶衍生物， 6-四氢吡啶衍生物。

    AUTOMOTIVE INNER CEILING MATERIAL AND MOLDING METHOD THEREOF
    55.
    发明申请
    AUTOMOTIVE INNER CEILING MATERIAL AND MOLDING METHOD THEREOF 审中-公开
    汽车内饰材料及其成型方法

    公开(公告)号：US20110084425A1

    公开(公告)日：2011-04-14

    申请号：US12971720

    申请日：2010-12-17

    申请人： Hisao Yamamoto

    发明人： Hisao Yamamoto

    IPC分类号： B29C43/02 ,  B29C43/52

    CPC分类号： D04H1/74 ,  B60R13/0225 ,  D01D5/34 ,  D01F8/14 ,  D04H1/435 ,  D04H1/4382 ,  D04H1/541 ,  D04H1/55 ,  Y10T442/641

    摘要： The present invention provides an automotive inner ceiling material difficult to deform at a high temperature. Sheath-core type conjugate polyester fibers are prepared. The sheath is a heat fusible component. The core is a non heat fusible component. The sheath is made of copolyester which comprises acid units made of terephthalic acid and diol unites made of ethylene glycol and 1,4-butanediol. The conjugate fibers and the main fibers of polyester are mixed and provided in a card machine to be opened and accumulated to obtain a fibrous web. The fibrous web is heated to melt the sheaths, which are thereafter solidified to bind the fibers to obtain a non woven fabric. The nonwoven fabric is heat-treated at a temperature equal to or higher than the melting point of the sheath. Immediately thereafter, the nonwoven fabric is heat-molded between a pair of a mold plates. During the heat-molding process, the inner temperature is maintained at 100˜130° C. for 60 seconds to obtain the ceiling material.

    摘要翻译： 本发明提供一种难以在高温下变形的汽车内顶板材料。 制备护芯型共轭聚酯纤维。 护套是热熔组件。 核心是非热熔组件。 鞘由共聚酯制成，其包含由对苯二甲酸和由乙二醇和1,4-丁二醇制成的二醇单元制成的酸单元。 将复合纤维和聚酯的主纤维混合并提供在卡片机中以打开和聚集以获得纤维网。 纤维网被加热以熔化护套，然后将其固化以结合纤维以获得无纺织物。 无纺布在等于或高于护套熔点的温度下进行热处理。 此后，立即将非织造布在一对模板之间进行热压成形。 在热成型过程中，将内部温度保持在100〜130℃，持续60秒，得到天花板材料。

    Traction type elevator apparatus
    57.
    发明授权
    Traction type elevator apparatus 失效
    牵引式电梯装置

    公开(公告)号：US06390243B2

    公开(公告)日：2002-05-21

    申请号：US09816219

    申请日：2001-03-26

    申请人： Kiyoshi Kobayashi ,  Tadashi Munakata ,  Kosei Kamimura ,  Yasuyuki Wagatsuma ,  Hisao Yamamoto ,  Koji Yajima

    发明人： Kiyoshi Kobayashi ,  Tadashi Munakata ,  Kosei Kamimura ,  Yasuyuki Wagatsuma ,  Hisao Yamamoto ,  Koji Yajima

    IPC分类号： B66B1108

    CPC分类号： B66B11/008

    摘要： An elevator apparatus is provided with an elevator path having a restricted height. Under a roping ratio of 1:1, a thin driving unit having a traction sheave 1 and a driving mechanism 2 is positioned between an inner wall 3a of the elevator path 3 and a space occupied by an elevator car 4 rising and falling in the elevator path 3. One end of a suspension rope 7 is fixed to the elevator car 4 in a position below a ceiling 4c of the elevator car 4. With the arrangement, the car 4 can move close to the ceiling 4c of the elevator car 4 effectively. Further, it is possible to reduce respective heights of the elevator path 3 and a building equipped with the elevator apparatus.

    摘要翻译： 电梯装置设有具有有限高度的电梯通道。 在1：1的绳索比下，具有牵引滑轮1和驱动机构2的薄驱动单元位于电梯通道3的内壁3a和升降电梯所占据的电梯轿厢4之间 悬挂绳索7的一端在电梯轿厢4的天花板4c下方的位置固定在电梯轿厢4上。由此，轿厢4能够有效地移动到电梯轿厢4的天花板4c附近 。 此外，可以降低电梯通道3和装备有电梯装置的建筑物的各自的高度。

    Traction type elevator apparatus
    59.
    发明授权
    Traction type elevator apparatus 失效
    牵引式电梯装置

    公开(公告)号：US06247557B1

    公开(公告)日：2001-06-19

    申请号：US09300072

    申请日：1999-04-27

    申请人： Kiyoshi Kobayashi ,  Tadashi Munakata ,  Kosei Kamimura ,  Yasuyuki Wagatsuma ,  Hisao Yamamoto ,  Koji Yajima

    发明人： Kiyoshi Kobayashi ,  Tadashi Munakata ,  Kosei Kamimura ,  Yasuyuki Wagatsuma ,  Hisao Yamamoto ,  Koji Yajima

    IPC分类号： B66B1108

    CPC分类号： B66B11/008

    摘要： An elevator apparatus including an elevator path having a restricted height. Under a roping ratio of 1:1, a thin driving unit having a traction sheave and a driving mechanism is positioned between an inner wall of the elevator path and a space occupied by an elevator car rising and falling in the elevator path. One end of a suspension rope is fixed to the elevator car in a position below a ceiling of the elevator car. With the arrangement, the car can move close to the ceiling of the elevator car effectively. Further, it is possible to reduce respective heights of the elevator path and a building equipped with the elevator apparatus.

    摘要翻译： 一种电梯装置，包括具有有限高度的电梯路径。 在1：1的绳索比下，具有牵引滑轮和驱动机构的薄驱动单元位于电梯路径的内壁和由电梯路径上升和下降的电梯轿厢占据的空间之间。 悬吊绳的一端在电梯轿厢的天花板下方的位置固定在电梯轿厢上。 通过这种安排，汽车可以有效地靠近电梯轿厢的天花板。 此外，可以减小电梯路径的各个高度和装备有电梯装置的建筑物。

    Method for the prevention of gastro-intestinal ulcer caused by a non-steroidal anti-inflammatory agent
    60.
    发明授权
    Method for the prevention of gastro-intestinal ulcer caused by a non-steroidal anti-inflammatory agent 失效
    用于预防由非甾体抗炎剂引起的胃肠溃疡的方法

    公开(公告)号：US4247554A

    公开(公告)日：1981-01-27

    申请号：US795887

    申请日：1977-05-11

    申请人： Hisao Yamamoto ,  Toshiaki Komatsu ,  Hiroshi Awata

    发明人： Hisao Yamamoto ,  Toshiaki Komatsu ,  Hiroshi Awata

    IPC分类号： A61K31/505

    CPC分类号： A61K31/505 ,  Y10S514/926 ,  Y10S514/927

    摘要： A method for preventing gastro-intestinal ulcer caused by a non-steroidal anti-inflammatory agent, which comprises administering an effective amount of a quinazolinone of the formula, ##STR1## wherein R.sub.1 is C.sub.1-3 alkyl, cyclopropylmethyl or 2,2,2-trifluoroethyl, R.sub.2 is halogen, C.sub.1-3 alkyl or C.sub.1-3 alkoxy, and R.sub.3 is phenyl or thienyl, or a non-toxic pharmaceutically acceptable salt thereof in combination with a pharmaceutically effective amount of the non-steroidal anti-inflammatory agent.

    摘要翻译： 一种用于预防由非甾体抗炎药引起的胃肠溃疡的方法，其包括给予有效量的下式的喹唑啉酮，其中R 1为C 1-3烷基，环丙基甲基或2,2,2 三氟乙基，R 2是卤素，C 1-3烷基或C 1-3烷氧基，R 3是苯基或噻吩基，或其无毒的药学上可接受的盐与药学上有效量的非甾体抗炎剂的组合。