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    OPHTHALMIC COMPOSITIONS AND METHODS FOR THE TREATMENT OF EYE DISORDERS
    58.
    发明申请
    OPHTHALMIC COMPOSITIONS AND METHODS FOR THE TREATMENT OF EYE DISORDERS 有权

    公开(公告)号：US20210277050A1

    公开(公告)日：2021-09-09

    申请号：US17250281

    申请日：2019-06-18

    申请人： Cellix Bio Private Limited

    发明人： Mahesh Kandula

    IPC分类号： C07J33/00 ,  C07J41/00 ,  C07D339/04 ,  C07C229/08 ,  C07D217/10 ,  C07D409/12 ,  A61P27/12

    摘要： The invention relates to the compounds or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II, formula III, formula IV, formula V, formula VI, formula VII, formula VIII, formula IX, formula X, formula XI formula XII, formula XIII, formula XIV, formula XV, formula XVI, or formula XVII and the methods for the treatment of eye diseases may be formulated for topical eye drop, topical paste, ocular solution, device-drug delivery, oral, buccal, rectal, topical, transdermal, transmucosal, lozenge, spray, intravenous, oral solution, nasal spray, oral solution, suspension, oral spray, buccal mucosal layer tablet, parenteral administration, syrup, or injection. Such compositions may be used to treatment of glaucoma, presbyopia, IOP, cataract, dry eye and oGVHD.

    USE OF SUBSTITUTED DIHYDROISOQUINOLINIUM SALTS FOR TREATING KERATIN MATERIALS, COMPOSITIONS AND IMPLEMENTATION PROCESSES
    59.
    发明申请
    USE OF SUBSTITUTED DIHYDROISOQUINOLINIUM SALTS FOR TREATING KERATIN MATERIALS, COMPOSITIONS AND IMPLEMENTATION PROCESSES 审中-公开

    公开(公告)号：US20190008742A1

    公开(公告)日：2019-01-10

    申请号：US16064291

    申请日：2016-12-23

    申请人： L'OREAL

    发明人： Stéphane SABELLE ,  Aziz FADLI ,  Alexandra CHARRIER

    IPC分类号： A61K8/49 ,  C07D217/10 ,  A61K8/22 ,  C07D217/14 ,  A61Q5/08

    摘要： The present invention relates to the use of one or more particular dihydroisoquinolinium salts of formula (I) for treating keratin materials, in particular keratin fibres, especially human keratin fibres such as the hair. The invention also relates to a process for treating keratin materials using said salts and optionally one or more chemical oxidizing agents. A subject of the invention is also a composition for lightening keratin materials, comprising one or more dihydroisoquinolinium salts and one or more chemical oxidizing agents. The present invention also relates to one or more particular dihydroisoquinolinium salts and also to compositions containing them, in particular compositions comprising a physiologically acceptable medium.