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公开(公告)号：US20220220088A1
公开(公告)日：2022-07-14
申请号：US17570420
申请日：2022-01-07
Inventor： Dong Wook KANG , Min Gi CHU , Seok Ju LEE , Eun Jung LEE
IPC: C07D311/32
Abstract: The present invention provides a method for producing fisetin or fisetin derivatives, which is capable of mass production. The method for producing fisetin or fisetin derivatives according to the present invention is capable of mass-producing fisetin or fisetin derivatives without a purification process such as a column chromatography process.
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公开(公告)号：US20210315957A1
公开(公告)日：2021-10-14
申请号：US17266610
申请日：2020-06-17
Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY , KOREA INSTITUTE OF ORIENTAL MEDICINE , DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
Inventor： Inho CHOI , Eun Ju LEE , So-young PARK , Yong-Ho LEE , Jin Yeul MA , Won-Kyung CHO , Hye Jin YANG
IPC: A61K36/484 , A61K9/00 , A61K31/353 , A61K31/12 , A61P21/00 , A23L33/00 , A23L33/105
Abstract: A pharmaceutical composition and a health functional food composition for preventing, treating, or improving muscular diseases have licorice extract or a fraction thereof, or a compound isolated therefrom or a pharmaceutically acceptable salt thereof, as an active ingredient. The licorice extract or a fraction thereof, the compound or salt thereof induce the myoblasts proliferation and promote the differentiation into myotubes, and since the licorice extract or a fraction thereof, the compound or salt thereof has an excellent effect on regenerating damaged muscles, various muscle diseases are effectively prevented, improved or treated using the composition.
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公开(公告)号：US10258662B2
公开(公告)日：2019-04-16
申请号：US14894210
申请日：2014-04-29
Applicant: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION , CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
Inventor： Choongho Lee , Tae Hwe Heo , Kee Dong Yoon
IPC: A61K36/87
Abstract: Provided is a method for preventing or treating hepatitis C by administrating a composition including, as an active ingredient, a Vitidis Vinferae Radix extract or a fraction thereof and, more specifically, to a Vitidis Vinferae Radix extract which is extracted with water and alcohol or a mixed solvent thereof, or a fraction thereof, which have remarkably low hepatotoxicity and exhibit an excellent effect of selectively inhibiting genome replication of a hepatitis C virus, and thus can be useful for preventing or treating hepatitis C.
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公开(公告)号：US20180271353A1
公开(公告)日：2018-09-27
申请号：US15996800
申请日：2018-06-04
Inventor： Hiun Suk CHAE
CPC classification number: A61B1/00089 , A61B1/00101 , A61B1/00137 , A61B1/012 , A61B1/31 , A61B1/32 , A61M25/09
Abstract: The present invention relates to an endoscope. The present invention may include an endoscope main body; and a guide cap that is mounted to be fixed to a front end of the endoscope main body when inserting the endoscope main body into a human body and slides to protrude toward the front of the endoscope main body when withdrawing the endoscope main body inserted into the human body. An object of the present invention is to facilitate insertion of the endoscope by freely varying a length of the cap from the front end of the endoscope, and to enhance the detection rate of polyp.
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公开(公告)号：US10004637B2
公开(公告)日：2018-06-26
申请号：US14436115
申请日：2013-10-18
Inventor： Choun-Ki Joo , Dong Jin Chang , Chong Houn Lee , Dong Kun Lee
IPC: A61F9/007
CPC classification number: A61F9/00736
Abstract: The present invention relates to an anterior capsulotomy guide device for cataract surgery. The present invention relates to an anterior capsulotomy guide device for cataract surgery which is temporarily inserted for anterior capsulotomy during cataract surgery, wherein the anterior capsulotomy guide device comprises a ring-shaped body, and a cut portion is formed by cutting a part of the body. According to the present invention, it is possible to carry out anterior capsulotomy with precise size and shape during cataract surgery, thereby maximizing the effect of cataract surgery.
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Patent Agency Ranking
公开(公告)号：US09943567B2
公开(公告)日：2018-04-17
申请号：US15481787
申请日：2017-04-07
Inventor： Jae-Hwan Nam , Hye-Lim Park , Dong-Hee Lee
IPC: A61K38/19 , A01K67/027 , A61K48/00
CPC classification number: A61K38/19 , A01K67/0275 , A01K67/0276 , A01K2217/054 , A01K2217/056 , A01K2217/15 , A01K2227/105 , A01K2267/0325 , A61K48/00 , A61K48/005 , C12N2750/14143
Abstract: The present invention relates to a pharmaceutical composition for treating and/or preventing arthritis, which comprising, as an active ingredient, a gene delivery vehicle into which an IK factor or a fragment thereof, or a nucleic acid encoding thereof is inserted. IK factor or the fragment thereof, and the nucleic acid encoding thereof, which are the active ingredient of the pharmaceutical composition according to the present invention, are derived from an organism and therefore, show no side effects in administered into a subject for a long time. Accordingly, they ensures safety and are expected to effectively treat arthritis by being involved in the upstream mechanism for suppressing arthritis.
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公开(公告)号：US20180087093A1
公开(公告)日：2018-03-29
申请号：US15617135
申请日：2017-06-08
Inventor： Yeun Jun CHUNG , Dong Gun LEE , Chul Min PARK , Bo Ram CHUNG
IPC: C12Q1/68
CPC classification number: C12Q1/689 , C12Q1/6818 , C12Q2600/156
Abstract: The present invention relates to a probe for detecting drug-resistant gram-positive pathogens, a probe set, and a method of detecting drug-resistant gram-positive pathogens using them. The probe for detecting drug-resistant gram-positive pathogens, the probe set, and the method for detecting drug-resistant gram-positive pathogens using them according to the present invention can contribute not only to shortening a detection time, compared to a conventional detection time, by optimizing a hybridization time, but also to increasing the sensitivity of detection by pre-amplification of the specific sequence of drug-resistant gram-positive pathogens, and thereby multiple detections of drug-resistant gram-positive pathogens can be accurately and efficiently performed.
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公开(公告)号：US20170283773A1
公开(公告)日：2017-10-05
申请号：US15463737
申请日：2017-03-20
Inventor： So-Hyang CHUNG , Hyun Jung LEE
IPC: C12N5/079
CPC classification number: C12N5/0621 , C12N2501/415 , C12N2533/30
Abstract: Provided are methods for improving the proliferation and sternness of limbal stem cells (LSCs) by adding a Wnt inhibitor to a medium for limbal explant cultures.When human limbal explants are cultured according to the methods, the Wnt/β-catenin signaling is inhibited, resulting in improvement of LSC proliferation, and improvement in the sternness of LSCs, and thus the LSCs may be obtained in high yield. These effects may lead to a higher success rate of transplantation of a limbal explant outgrowth sheet into a LSCD patient.
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公开(公告)号：US09737588B2
公开(公告)日：2017-08-22
申请号：US14784614
申请日：2014-04-16
Inventor： Jae-Hwan Nam , Hye-Lim Park , Dong-Hee Lee
IPC: A61K38/19 , A61K48/00 , A01K67/027 , A61K38/21
CPC classification number: A61K38/19 , A01K67/0275 , A01K67/0276 , A01K2217/054 , A01K2217/056 , A01K2217/15 , A01K2227/105 , A01K2267/0325 , A61K48/00 , A61K48/005 , C12N2750/14143
Abstract: The present invention relates to a pharmaceutical composition for treating and/or preventing arthritis, which comprising, as an active ingredient, a gene delivery vehicle into which an IK factor or a fragment thereof, or a nucleic acid encoding thereof is inserted. IK factor or the fragment thereof, and the nucleic acid encoding thereof, which are the active ingredient of the pharmaceutical composition according to the present invention, are derived from an organism and therefore, show no side effects in administered into a subject for a long time. Accordingly, they ensures safety and are expected to effectively treat arthritis by being involved in the upstream mechanism for suppressing arthritis.
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公开(公告)号：US20170000452A1
公开(公告)日：2017-01-05
申请号：US15101071
申请日：2015-04-02
Inventor： TAE SUK SUH , MIN YOUNG LEE , JI YEON PARK , JEONG WOO LEE , JOON YONG CHOI , SANG WON KANG , HAE JIN PARK
IPC: A61B6/00
CPC classification number: A61B6/583 , A61B6/032 , A61B6/14 , A61B6/542 , G01T1/06 , G01T1/11 , G01T1/169
Abstract: The present invention relates to a head and neck simulation phantom device for simulating the head and neck of a body, the phantom device including: a flat type first plate having a first insertion groove formed on one surface thereof; a flat type second plate disposed to come into contact with the other surface of the first plate and having a second insertion groove formed on the contacted surface with the other surface of the first plate in such a manner as to correspond to the first insertion groove;and a plurality of teeth simulants inserted into the first insertion groove and the second insertion groove and for simulating the teeth of the body.
Abstract translation: 以及插入到第一插入槽和第二插入槽中并用于模拟身体的齿的多个牙齿模拟器。
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