公开(公告)号：US08260577B2

公开(公告)日：2012-09-04

申请号：US13007109

申请日：2011-01-14

申请人： Walter M. Weber ,  Ammar Al-Ali ,  Lorenzo Cazzoli

发明人： Walter M. Weber ,  Ammar Al-Ali ,  Lorenzo Cazzoli

IPC分类号： G06F19/00

CPC分类号： A61B5/7271 ,  A61B5/0002 ,  A61B5/021 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/72 ,  A61B5/7207 ,  A61B5/7239 ,  G06K9/0051

摘要： A variable indication estimator which determines an output value representative of a set of input data. For example, the estimator can reduce input data to estimates of a desired signal, select a time, and determine an output value from the estimates and the time. In one embodiment, the time is selected using one or more adjustable signal confidence parameters determine where along the estimates the output value will be computed. By varying the parameters, the characteristics of the output value are variable. For example, when input signal confidence is low, the parameters are adjusted so that the output value is a smoothed representation of the input signal. When input signal confidence is high, the parameters are adjusted so that the output value has a faster and more accurate response to the input signal.

摘要翻译： 可变指示估计器，其确定代表一组输入数据的输出值。 例如，估计器可以将输入数据减少到期望信号的估计，选择时间，并从估计和时间确定输出值。 在一个实施例中，使用一个或多个可调信号置信参数来选择时间，确定沿着估计将在哪里计算输出值。 通过改变参数，输出值的特性是可变的。 例如，当输入信号置信度低时，调整参数，使得输出值是输入信号的平滑表示。 当输入信号置信度高时，调整参数，使得输出值对输入信号的响应更快更准确。

公开(公告)号：US20110160552A1

公开(公告)日：2011-06-30

申请号：US13043421

申请日：2011-03-08

申请人： Walter M. Weber ,  Ammar Al-Ali ,  Lorenzo Cazzoli

发明人： Walter M. Weber ,  Ammar Al-Ali ,  Lorenzo Cazzoli

IPC分类号： A61B5/1455

CPC分类号： A61B5/14552 ,  A61B5/024 ,  A61B5/02433 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/7282

摘要： A transform for determining a physiological measurement is disclosed. The transform determines a basis function index from a physiological signal obtained through a physiological sensor. A basis function waveform is generated based on basis function index. The basis function waveform is then used to determine an optimized basis function waveform. The optimized basis function waveform is used to calculate a physiological measurement.

摘要翻译： 公开了用于确定生理测量的变换。 该变换根据通过生理传感器获得的生理信号确定基函数指数。 基于功能指标生成基函数波形。 然后基函数波形用于确定优化的基函数波形。 优化的基函数波形用于计算生理测量。

公开(公告)号：US20110098543A1

公开(公告)日：2011-04-28

申请号：US12983823

申请日：2011-01-03

申请人： Walter M. Weber ,  Ammar Al-Ali

发明人： Walter M. Weber ,  Ammar Al-Ali

IPC分类号： A61B5/1455

CPC分类号： A61B5/7228 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7214 ,  A61B5/7221 ,  A61B2562/0238

摘要： A method and an apparatus for separating a composite signal into a plurality of signals is described. A signal processor receives a composite signal and separates a composite signal in to separate output signals. Feedback from one or more of the output signals is provided to a configuration module that configures the signal processor to improve a quality of the output signals. In one embodiment, the signal processor separates the composite signal by applying a first demodulation scheme to the composite signal to generate a first output signal. In one embodiment, the signal processor also applies a second demodulation scheme to the composite signal to generate a second output signal. In one embodiment, the composite signal is obtained from a detector in a system for measuring one or more blood constituents.

摘要翻译： 描述用于将复合信号分离成多个信号的方法和装置。 信号处理器接收复合信号并将复合信号分离成分离的输出信号。 来自一个或多个输出信号的反馈被提供给配置模块，其配置信号处理器以提高输出信号的质量。 在一个实施例中，信号处理器通过对复合信号应用第一解调方案来分离复合信号以产生第一输出信号。 在一个实施例中，信号处理器还对复合信号施加第二解调方案以产生第二输出信号。 在一个实施例中，复合信号从用于测量一个或多个血液成分的系统中的检测器获得。

公开(公告)号：US07865222B2

公开(公告)日：2011-01-04

申请号：US11371242

申请日：2006-01-23

申请人： Walter M. Weber ,  Ammar Al-Ali

发明人： Walter M. Weber ,  Ammar Al-Ali

IPC分类号： A61B5/1455 ,  H04B15/00

CPC分类号： A61B5/7228 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7214 ,  A61B5/7221 ,  A61B2562/0238

摘要： A method and an apparatus for separating a composite signal into a plurality of signals is described. A signal processor receives a composite signal and separates a composite signal in to separate output signals. Feedback from one or more of the output signals is provided to a configuration module that configures the signal processor to improve a quality of the output signals. In one embodiment, the signal processor separates the composite signal by applying a first demodulation signal to the composite signal to generate a first output signal. In one embodiment, the signal processor also applies a second demodulation signal to the composite signal to generate a second output signal. In one embodiment, a phase and/or amplitude of the first demodulation signal and a phase and/or amplitude of the second demodulation signal are selected to reduce crosstalk. In one embodiment, the composite signal is obtained from a detector in a system for measuring one or more blood constituents.

摘要翻译： 描述用于将复合信号分离成多个信号的方法和装置。 信号处理器接收复合信号并将复合信号分离成分离的输出信号。 来自一个或多个输出信号的反馈被提供给配置模块，其配置信号处理器以提高输出信号的质量。 在一个实施例中，信号处理器通过将第一解调信号施加到复合信号来分离合成信号，以产生第一输出信号。 在一个实施例中，信号处理器还将第二解调信号施加到复合信号以产生第二输出信号。 在一个实施例中，选择第一解调信号的相位和/或振幅以及第二解调信号的相位和/或幅度以减少串扰。 在一个实施例中，复合信号从用于测量一个或多个血液成分的系统中的检测器获得。

公开(公告)号：US07373194B2

公开(公告)日：2008-05-13

申请号：US11048232

申请日：2005-02-01

申请人： Walter M. Weber ,  Ammar Al-Ali ,  Lorenzo Cazzoli

发明人： Walter M. Weber ,  Ammar Al-Ali ,  Lorenzo Cazzoli

IPC分类号： A61B5/1455

CPC分类号： A61B5/14552 ,  A61B5/024 ,  A61B5/02433 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/7282

摘要： A signal processor generates basis functions and identifies at least one basis function component of a sensor signal in order to calculate a physiological measurement. The signal processor is advantageously applied to pulse oximetry so as to directly calculate oxygen saturation and so as to calculate a robust oxygen saturation measurement. In particular, a signal component transform may be calculated within a window around a derived pulse rate estimate. A signal component transform may also utilize sinusoidal basis functions, and an optimization of a signal component transform may occur at a particular frequency or a set of frequencies. A sinusoidal waveform or waveforms at that frequency or set of frequencies is generated to select associated red and infrared components of the sensor signal, and an oxygen saturation is calculated from a magnitude ratio of these components.

摘要翻译： 信号处理器生成基函数并且识别传感器信号的至少一个基函数分量，以便计算生理测量。 信号处理器有利地应用于脉搏血氧饱和度，以便直接计算氧饱和度，以便计算鲁棒的氧饱和度测量。 特别地，可以在围绕导出的脉冲率估计的窗口内计算信号分量变换。 信号分量变换还可以利用正弦基函数，并且可以在特定频率或一组频率处发生信号分量变换的优化。 产生在该频率或频率组中的正弦波形或波形以选择传感器信号的相关红色和红外分量，并且根据这些分量的幅度比计算氧饱和度。

公开(公告)号：US07254431B2

公开(公告)日：2007-08-07

申请号：US10930048

申请日：2004-08-30

申请人： Ammar Al-Ali ,  Mohamed Diab ,  Walter M. Weber

发明人： Ammar Al-Ali ,  Mohamed Diab ,  Walter M. Weber

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/72 ,  A61B2560/0204

摘要： A physiological parameter tracking system generates a reference parameter and a slowly varying parameter responsive to a physiological signal input. The slowly varying parameter is generated according to an update command. A physiological measurement output is provided that is responsive to a tracking function of the reference parameter and the slowly varying parameter.

摘要翻译： 生理参数跟踪系统响应于生理信号输入产生参考参数和缓慢变化的参数。 根据更新命令生成缓慢变化的参数。 提供响应于参考参数和缓慢变化参数的跟踪功能的生理测量输出。

公开(公告)号：US07003339B2

公开(公告)日：2006-02-21

申请号：US10700324

申请日：2003-11-03

申请人： Mohamed K. Diab ,  Walter M. Weber ,  Ammar Al-Ali

发明人： Mohamed K. Diab ,  Walter M. Weber ,  Ammar Al-Ali

IPC分类号： A61B5/00

CPC分类号： A61B5/7228 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7217 ,  A61B5/7232 ,  A61B2560/0242 ,  A61B2562/0238 ,  H04J3/10 ,  H04J14/08

摘要： A method and an apparatus measure blood oxygenation in a subject. A first signal source applies a first input signal during a first time interval. A second signal source applies a second input signal during a second time interval. A detector detects a first parametric signal responsive to the first input signal passing through a portion of the subject having blood therein. The detector also detects a second parametric signal responsive to the second input signal passing through the portion of the subject. The detector generates a detector output signal responsive to the first and second parametric signals. A signal processor receives the detector output signal and demodulates the detector output signal by applying a first demodulation signal to a signal responsive to the detector output signal to generate a first output signal responsive to the first parametric signal. The signal processor applies a second demodulation signal to the signal responsive to the detector output signal to generate a second output signal responsive to the second parametric signal. The first demodulation signal and the second demodulation signal both include at least a first component having a first frequency and a first amplitude and a second component having a second frequency and a second amplitude. The second frequency is a harmonic of the first frequency. The second amplitude is related to the first amplitude to minimize crosstalk from the first parametric signal to the second output signal and to minimize crosstalk from the second parametric signal to the first output signal.

公开(公告)号：US07003338B2

公开(公告)日：2006-02-21

申请号：US10615333

申请日：2003-07-08

申请人： Walter M. Weber ,  Ammar Al-Ali

发明人： Walter M. Weber ,  Ammar Al-Ali

IPC分类号： A61B5/00

CPC分类号： A61B5/7228 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7214 ,  A61B5/7221 ,  A61B2562/0238

摘要： A method and an apparatus for separating a composite signal into a plurality of signals is described. A signal processor receives a composite signal and separates a composite signal in to separate output signals. Feedback from one or more of the output signals is provided to a configuration module that configures the signal processor to improve a quality of the output signals. In one embodiment, the signal processor separates the composite signal by applying a first demodulation signal to the composite signal to generate a first output signal. In one embodiment, the signal processor also applies a second demodulation signal to the composite signal to generate a second output signal. In one embodiment, a phase and/or amplitude of the first demodulation signal and a phase and/or amplitude of the second demodulation signal are selected to reduce crosstalk. In one embodiment, the composite signal is obtained from a detector in a system for measuring one or more blood constituents.

摘要翻译： 描述用于将复合信号分离成多个信号的方法和装置。 信号处理器接收复合信号并将复合信号分离成分离的输出信号。 来自一个或多个输出信号的反馈被提供给配置模块，其配置信号处理器以提高输出信号的质量。 在一个实施例中，信号处理器通过将第一解调信号施加到复合信号来分离合成信号，以产生第一输出信号。 在一个实施例中，信号处理器还将第二解调信号施加到复合信号以产生第二输出信号。 在一个实施例中，选择第一解调信号的相位和/或振幅以及第二解调信号的相位和/或幅度以减少串扰。 在一个实施例中，复合信号从用于测量一个或多个血液成分的系统中的检测器获得。

公开(公告)号：US06999904B2

公开(公告)日：2006-02-14

申请号：US10213270

申请日：2002-08-05

申请人： Walter M. Weber ,  Ammar Al-Ali ,  Lorenzo Cazzoll

发明人： Walter M. Weber ,  Ammar Al-Ali ,  Lorenzo Cazzoll

IPC分类号： A61B5/00

CPC分类号： A61B5/7271 ,  A61B5/0002 ,  A61B5/021 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/72 ,  A61B5/7207 ,  A61B5/7239 ,  G06K9/0051

摘要： A variable indication estimator which determines an output value representative of a set of input data. For example, the estimator can reduce input data to estimates of a desired signal, select a time, and determine an output value from the estimates and the time. In one embodiment, the time is selected using one or more adjustable signal confidence parameters determine where along the estimates the output value will be computed. By varying the parameters, the characteristics of the output value are variable. For example, when input signal confidence is low, the parameters are adjusted so that the output value is a smoothed representation of the input signal. When input signal confidence is high, the parameters are adjusted so that the output value has a faster and more accurate response to the input signal.

公开(公告)号：US09192329B2

公开(公告)日：2015-11-24

申请号：US11871808

申请日：2007-10-12

申请人： Ammar Al-Ali

发明人： Ammar Al-Ali

IPC分类号： A61B5/02 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/024

CPC分类号： A61B5/02427 ,  A61B5/0002 ,  A61B5/02438 ,  A61B5/14551 ,  A61B5/6826 ,  A61B5/6838 ,  A61B5/7405 ,  A61B5/742

摘要： A user configurable variable mode pulse indicator provides a user the ability to influence outputs indicative of a pulse occurrence at least during distortion, or high-noise events. For example, when configured to provide or trigger pulse indication outputs, a pulse indicator designates the occurrence of each pulse in a pulse oximeter-derived photo-plethysmograph waveform, through waveform analysis or some statistical measure of the pulse rate, such as an averaged pulse rate. When the configured to block outputs or not trigger pulse indication outputs, a pulse indicator disables the output for one or more of an audio or visual pulse occurrence indication. The outputs can be used to initiate an audible tone “beep” or a visual pulse indication on a display, such as a vertical spike on a horizontal trace or a corresponding indication on a bar display. The amplitude output is used to indicate data integrity and corresponding confidence in the computed values of saturation and pulse rate. The amplitude output can vary a characteristic of the pulse indicator, such as beep volume or frequency or the height of the visual display spike.

摘要翻译： 用户可配置的可变模式脉冲指示器至少在失真或高噪声事件期间使用户能够影响指示脉冲出现的输出。 例如，当配置为提供或触发脉冲指示输出时，脉冲指示器通过波形分析或脉搏率的某种统计测量来指定脉冲血氧计衍生的光体积描记器波形中每个脉冲的出现，例如平均脉冲 率。 当配置为阻止输出或不触发脉冲指示输出时，脉冲指示器会禁用输出中的一个或多个音频或视觉脉冲发生指示。 输出可用于在显示器上启动可听见的音调“哔”或视觉脉搏指示，例如水平轨迹上的垂直尖峰或条形显示器上的相应指示。 振幅输出用于指示计算的饱和度和脉率值的数据完整性和相应的置信度。 振幅输出可以改变脉冲指示器的特性，例如哔音体积或频率或视觉显示尖峰的高度。