Augmenting reality system for real-time nanomanipulation using atomic force microscopy
    61.
    发明授权
    Augmenting reality system for real-time nanomanipulation using atomic force microscopy 失效
    使用原子力显微镜增强现实系统的实时纳米操纵

    公开(公告)号:US06862924B2

    公开(公告)日:2005-03-08

    申请号:US10428578

    申请日:2003-05-02

    摘要: An improved method is provided for performing nanomanipulations using an atomic force microscope. The method includes: performing a nanomanipulation operation on a sample surface using an atomic force microscope; determining force data for forces that are being applied to the tip of the cantilever during the nanomanipulation operation, where the force data is derived along at least two perpendicularly arranged axis; and updating a model which represents the topography of the sample surface using the force data.

    摘要翻译: 提供了一种使用原子力显微镜进行纳米操作的改进方法。 该方法包括:使用原子力显微镜对样品表面进行纳米操作操作; 确定在纳米操纵操作期间施加到悬臂的尖端的力的力数据,其中力数据沿着至少两个垂直布置的轴被导出; 以及使用力数据更新表示样品表面的形貌的模型。

    Heteroaromatic compounds as PI3 kinase modulators and methods of use
    62.
    发明授权
    Heteroaromatic compounds as PI3 kinase modulators and methods of use 有权
    杂环化合物作为PI3激酶调节剂和使用方法

    公开(公告)号:US09573953B2

    公开(公告)日:2017-02-21

    申请号:US14181670

    申请日:2014-02-15

    申请人: Ning Xi

    发明人: Ning Xi

    摘要: The present invention provides heteroaromatic derivatives and pharmaceutical acceptable salts and formulations thereof useful in modulating the protein kinase activity, especially phosphatidylinositol 3-kinases (PI3 kinases) and mTOR, and in modulating inter- and/or intra-cellular signaling activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

    摘要翻译: 本发明提供了可用于调节蛋白激酶活性的杂芳族衍生物及其药学上可接受的盐和制剂,特别是磷脂酰肌醇3-激酶(PI3激酶)和mTOR,以及调节细胞间和/或细胞内信号活动如增殖, 分化,凋亡,迁移和侵袭。 本发明还提供包含这些化合物的药学上可接受的组合物和使用该组合物治疗哺乳动物,特别是人类中过度增殖性疾病的方法。

    JUMPING ROBOT
    63.
    发明申请
    JUMPING ROBOT 有权
    摔跤机器人

    公开(公告)号:US20130282174A1

    公开(公告)日:2013-10-24

    申请号:US13832284

    申请日:2013-03-15

    IPC分类号: B25J9/16

    摘要: A jumping robot is provided. In another aspect, a jumping robot weighs less than 50 grams, jumps at least 20 cm high and has a maximum linear dimension of 10 cm. A further aspect provides a robot that employs an electromagnetic actuator that actuates at least two of: jumping, steering, self-righting, and/or mid-air orientation control.

    摘要翻译: 提供跳跃机器人。 在另一方面,跳跃机器人重量小于50克,跳跃至少20厘米高,最大直线尺寸为10厘米。 另一方面提供了一种使用致动器的电磁致动器的机器人,其致动:跳跃,转向,自对准和/或空中取向控制中的至少两个。

    Adaptable end effector for atomic force microscopy based nano robotic manipulators
    69.
    发明授权
    Adaptable end effector for atomic force microscopy based nano robotic manipulators 失效
    适用于基于原子力显微镜的纳米机器人操纵器的末端执行器

    公开(公告)号:US07406859B2

    公开(公告)日:2008-08-05

    申请号:US11399690

    申请日:2006-04-06

    IPC分类号: G01B5/28

    摘要: An improved nanomanipulation system is provided for performing nanomanipulation operations in relation to a sample surface. The system includes: an atomic force microscope having a probe for performing nanomanipulation operations on the sample surface, where the probe includes a cantilever having a layer of piezoelectric material; a position detector configured to ascertain deformation of the cantilever during a nanomanipulation operation; and an adaptable end effector controller adapted to receive data indicative of the deformation from the position detector and implements a control scheme based on the deformation data. The control scheme produces a control signal that is applied to the piezoelectric material of the cantilever, thereby maintaining the straight shape of the cantilever during the nanomanipulation operation.

    摘要翻译: 提供改进的纳米操纵系统用于相对于样品表面进行纳米操纵操作。 该系统包括:原子力显微镜,具有用于对样品表面进行纳米操作操作的探针,其中探针包括具有一层压电材料的悬臂; 位置检测器,其构造成在纳米操作操作期间确定所述悬臂的变形; 以及可适应的末端执行器控制器,其适于接收表示来自位置检测器的变形的数据,并且基于变形数据实现控制方案。 控制方案产生施加到悬臂的压电材料的控制信号,从而在纳米操作操作期间保持悬臂的直线形状。

    DETERMINISTIC PROCESS FOR CONSTRUCTING NANODEVICES
    70.
    发明申请
    DETERMINISTIC PROCESS FOR CONSTRUCTING NANODEVICES 失效
    用于构建纳米器件的确定方法

    公开(公告)号:US20080108172A1

    公开(公告)日:2008-05-08

    申请号:US11546499

    申请日:2006-10-11

    IPC分类号: H01L51/40

    摘要: A method is provided for constructing a nanodevice. The method includes: fabricating an electrode on a substrate; forming a nanogap across the electrode; dispersing a plurality of nanoobjects onto the substrate using electrophoresis; and pushing one of the nanoobjects onto the electrode using a tip of an atomic force microscope, such that the nanoobject lies across the nanogap formed in the electrode. In addition, remaining nanoobjects may also be pushed away from the electrode using the atomic force microscope, thereby completing construction of a nanodevice.

    摘要翻译: 提供了一种构造纳米器件的方法。 该方法包括:在基板上制造电极; 在电极上形成纳米隙; 使用电泳将多个纳米对象分散到基底上; 并使用原子力显微镜的尖端将一个纳米对象推到电极上,使得纳米对象位于电极中形成的纳米隙上。 此外,还可以使用原子力显微镜将剩余的纳米对象推离电极,从而完成纳米器件的构造。