公开(公告)号：US10918317B2

公开(公告)日：2021-02-16

申请号：US16528379

申请日：2019-07-31

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, Jr. ,  James H. Brauker ,  Aarthi Mahalingam

IPC: A61B5/1473 ,  A61B5/1486 ,  A61B5/1468 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/00

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20210038136A1

公开(公告)日：2021-02-11

申请号：US17076730

申请日：2020-10-21

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Jack Pryor ,  Paul V. Goode, JR. ,  James H. Brauker ,  Aarthi Mahalingam

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1495

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20210022653A1

公开(公告)日：2021-01-28

申请号：US17035478

申请日：2020-09-28

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Robert J. Boock ,  Monica A. Rixman ,  Peter C. Simpson ,  Mark C. Brister ,  Mark C. Shults

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  C12Q1/00 ,  G01N33/543 ,  G01N33/66

Abstract: Biointerface membranes are provided which can be utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device incorporating such membranes are provided.

公开(公告)号：US10898114B2

公开(公告)日：2021-01-26

申请号：US16691107

申请日：2019-11-21

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  James H. Brauker ,  Paul V. Goode, Jr. ,  Aarthi Mahalingam ,  Jack Pryor

IPC: A61B5/1486 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/00

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20200375515A1

公开(公告)日：2020-12-03

申请号：US16998841

申请日：2020-08-20

Applicant: DexCom, Inc.

Inventor： Mark Shults ,  James H. Brauker ,  Victoria Carr-Brendel ,  Mark Tapsak ,  Dubravka Markovic

IPC: A61B5/1486 ,  A61B5/145 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16

Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.

公开(公告)号：US20200330684A1

公开(公告)日：2020-10-22

申请号：US16852369

申请日：2020-04-17

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: A61M5/172 ,  A61B5/145 ,  A61M5/142 ,  A61M11/00 ,  A61M15/00 ,  G16H40/63 ,  G16H20/17 ,  A61M35/00 ,  A61M5/20

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

公开(公告)号：US20200289038A1

公开(公告)日：2020-09-17

申请号：US16889646

申请日：2020-06-01

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1486 ,  C12Q1/00

Abstract: Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.

公开(公告)号：US10716498B2

公开(公告)日：2020-07-21

申请号：US16691325

申请日：2019-11-21

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  James H. Brauker ,  Paul V. Goode, Jr. ,  Aarthi Mahalingam ,  Jack Pryor

IPC: A61B5/1495 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/00

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20190320952A1

公开(公告)日：2019-10-24

申请号：US16457628

申请日：2019-06-28

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, JR. ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/1473

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20190320951A1

公开(公告)日：2019-10-24

申请号：US16457383

申请日：2019-06-28

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, JR. ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/1473

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.