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公开(公告)号:US20120196846A1
公开(公告)日:2012-08-02
申请号:US13383180
申请日:2010-07-07
申请人: Richard L. Mackman , David Sperandio , Hai Yang
发明人: Richard L. Mackman , David Sperandio , Hai Yang
IPC分类号: A61K31/55 , A61P29/00 , A61P31/12 , C07D223/14 , A61P31/14
CPC分类号: C07D495/04
摘要: The present invention relates to anti-RSV compounds of Formula (I) and methods for use of the compounds in the treatment and prevention of RSV infection.
摘要翻译: 本发明涉及式(I)的抗RSV化合物及其用于治疗和预防RSV感染的方法。
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公开(公告)号:US20120003215A1
公开(公告)日:2012-01-05
申请号:US13167618
申请日:2011-06-23
申请人: Kerim Babaoglu , Constantine G. Boojamra , Eugene J. Eisenberg , Hon Chung Hui , Richard L. Mackman , Jay P. Parrish , Michael Sangi , Oliver L. Saunders , Dustin Siegel , David Sperandio , Hai Yang
发明人: Kerim Babaoglu , Constantine G. Boojamra , Eugene J. Eisenberg , Hon Chung Hui , Richard L. Mackman , Jay P. Parrish , Michael Sangi , Oliver L. Saunders , Dustin Siegel , David Sperandio , Hai Yang
IPC分类号: A61K31/519 , C07D413/14 , A61P31/14 , A61K31/7056 , A61K39/42 , C07D487/04 , A61K31/5377
CPC分类号: C07D487/04 , A61K31/519 , A61K31/5377 , A61K31/55 , A61K31/551 , A61K31/675 , A61K45/06 , C07D495/04 , C07D513/04 , C07D519/00 , C07F9/65616
摘要: The invention provides compounds of Formula I or Formula II: or a pharmaceutically acceptable salt or ester, thereof, as described herein. The compounds and compositions thereof are useful for treating Pneumovirinae virus infections. The compounds, compositions, and methods provided are particularly useful for the treatment of Human respiratory syncytial virus infections.
摘要翻译: 本发明提供了本文所述的式I或式II化合物或其药学上可接受的盐或酯。 其化合物及其组合物可用于治疗肺炎链球菌病毒感染。 提供的化合物,组合物和方法特别可用于治疗人呼吸道合胞病毒感染。
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公开(公告)号:US20080145723A1
公开(公告)日:2008-06-19
申请号:US11639941
申请日:2006-12-15
申请人: Shengxian Wang , Andrew Philip Shapiro , Jun Cai , Hai Yang , Rihua Xiong , Chang Wei , Bing Zhang , Qunjian Huang
发明人: Shengxian Wang , Andrew Philip Shapiro , Jun Cai , Hai Yang , Rihua Xiong , Chang Wei , Bing Zhang , Qunjian Huang
CPC分类号: H01M8/065 , H01M4/242 , H01M4/26 , H01M4/62 , H01M4/98 , H01M6/5005 , H01M8/04119 , H01M8/186 , H01M8/24 , H01M12/08 , H01M2004/027 , Y02E60/128
摘要: An apparatus for controlling humidity in a fuel cell is provided. The apparatus can include a housing having an interior surface defining a volume and containing at least one fuel cell disposed within the volume. The apparatus may also include a plurality of electrodes disposed within the volume. The apparatus can include an aperture defined by the housing through which at least one air gas stream can be in fluid communication with at least one of the plurality of electrodes. The apparatus can include a humidity-controlling component, wherein the humidity-controlling component is in fluid communication with the air gas stream prior to the air gas stream contacting the at least one of the plurality of electrodes, and humidity-controlling component being capable of controlling a relative humidity of the air gas stream. A method for controlling humidity in a fuel cell is provided.
摘要翻译: 提供一种用于控制燃料电池中的湿度的装置。 该装置可以包括壳体,其具有限定体积的内表面并且包含设置在体积内的至少一个燃料电池。 该装置还可以包括设置在该体积内的多个电极。 该装置可以包括由壳体限定的孔,至少一个空气气体流可以与多个电极中的至少一个流体连通。 所述装置可以包括湿度控制部件,其中所述湿度控制部件在所述空气流与所述多个电极中的至少一个接触之前与所述空气流体流体连通,并且所述调湿部件能够 控制气流的相对湿度。 提供了一种用于控制燃料电池中的湿度的方法。
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公开(公告)号:US20070141450A1
公开(公告)日:2007-06-21
申请号:US11313634
申请日:2005-12-21
申请人: Hai Yang , Qunjian Huang , Chang Wei , Jun Cai , Jinghua Liu , Shengxian Wang , Qijia Fu
发明人: Hai Yang , Qunjian Huang , Chang Wei , Jun Cai , Jinghua Liu , Shengxian Wang , Qijia Fu
CPC分类号: H01M8/0273 , H01M4/90 , H01M4/96 , H01M8/04141 , H01M8/04149 , H01M8/04156 , H01M8/083 , H01M8/186 , H01M8/2475 , H01M10/281 , H01M12/08 , H01M16/003 , H01M2008/1095 , H01M2250/20 , Y02E60/124 , Y02E60/128 , Y02T90/32
摘要: A fuel cell assembly may be provided that includes a first cathodic electrode and a second cathodic electrode; an anodic electrode positioned between the first cathodic electrode and the second cathodic electrode; a first membrane positioned between the first cathodic electrode and the anodic electrode; a second membrane positioned between the second cathodic electrode and the anodic electrode; and a seal ring for sealing the fuel cell assembly, the seal ring comprising a water-refilling mechanism.
摘要翻译: 可以提供包括第一阴极电极和第二阴极电极的燃料电池组件; 位于第一阴极电极和第二阴极电极之间的阳极; 位于所述第一阴极电极和所述阳极电极之间的第一膜; 位于所述第二阴极电极和所述阳极电极之间的第二膜; 以及用于密封燃料电池组件的密封环,所述密封环包括水重新填充机构。
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公开(公告)号:US20070141440A1
公开(公告)日:2007-06-21
申请号:US11314226
申请日:2005-12-21
申请人: Hai Yang , Jun Cai , Jinghua Liu , Chang Wei , Qunjian Huang , Shengxian Wang , Qijia Fu
发明人: Hai Yang , Jun Cai , Jinghua Liu , Chang Wei , Qunjian Huang , Shengxian Wang , Qijia Fu
CPC分类号: H01M12/08 , H01M4/383 , H01M6/5005 , H01M8/225 , H01M12/06 , H01M2300/0014 , Y02E60/128
摘要: A galvanic cell structure is provided. The galvanic cell structure includes an outer cylinder featuring air inlets, a cathode, an anode, a membrane separating the cathode from the anode, and an inner cylinder featuring fluid inlets that may provide a volume for storing and/or transferring fluid for use in the galvanic cell.
摘要翻译: 提供电池结构。 电池单元结构包括具有空气入口的外圆筒,阴极,阳极,将阴极与阳极分开的膜,以及具有流体入口的内圆筒,其可提供用于储存和/或转移流体的体积 原电池。
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公开(公告)号:US20070141415A1
公开(公告)日:2007-06-21
申请号:US11566347
申请日:2006-12-04
申请人: Hai Yang , Chang Wei , Qunjian Huang , Jinghua Liu , Rihua Xiong , Jun Cai , Shengxian Wang
发明人: Hai Yang , Chang Wei , Qunjian Huang , Jinghua Liu , Rihua Xiong , Jun Cai , Shengxian Wang
CPC分类号: H01M12/005 , H01G9/08 , H01G9/155 , H01M8/04119 , H01M8/04216 , H01M8/18 , H01M12/06 , Y02E60/13
摘要: An apparatus including a housing having walls is provided. The walls of the housing each have inner surfaces and outer surfaces. The walls may include apertures extending from the inner surface to the outer surface. The inner surfaces of the walls define a volume. The volume includes an electrode. The volume further includes a water-controlling separator disposed between the inner surface of the housing and the electrode. The water-controlling separator can block a flow of liquid from the electrode through the apertures to the ambient environment while allowing oxidant to flow from the ambient environment through the apertures to the electrode.
摘要翻译: 提供一种包括具有壁的壳体的装置。 壳体的壁各自具有内表面和外表面。 壁可以包括从内表面延伸到外表面的孔。 壁的内表面定义一个体积。 体积包括电极。 体积还包括设置在壳体的内表面和电极之间的防水分离器。 水控制分离器可以阻止液体从电极通过孔流到周围环境,同时允许氧化剂从周围环境通过孔流动到电极。
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