公开(公告)号：US08475779B2

公开(公告)日：2013-07-02

申请号：US12637723

申请日：2009-12-14

Applicant: James Rasmussen ,  Jianxin Zhang ,  Sam Baldwin ,  Eric Zanelli ,  Bei Yu ,  Dustan Bonnin ,  Keith Johnson

Inventor： James Rasmussen ,  Jianxin Zhang ,  Sam Baldwin ,  Eric Zanelli ,  Bei Yu ,  Dustan Bonnin ,  Keith Johnson

IPC: A61K9/107 ,  A61K31/74 ,  A61K38/02

CPC classification number: A61K38/02 ,  A61K38/16 ,  A61K2300/00

Abstract: The invention relates to novel methods and kits for treating or preventing disease through the administration of random copolymers comprising amino acids tyrosine (Y), phenylalanine (F), alanine (A), and lysine (K). The invention also relates to the treatment of autoimmune diseases, such as multiple sclerosis, and to the administration of random copolymers in treatment regimen comprising formulations that are administered at intervals greater than 24 hours, or to sustained release formulations which administer the copolymer over a period greater than 24 hours. The invention further relates to methods for conducting a pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the formulations or dosing regimens of random copolymer described herein.

Abstract translation: 本发明涉及通过施用包含氨基酸酪氨酸（Y），苯丙氨酸（F），丙氨酸（A）和赖氨酸（K））的无规共聚物来治疗或预防疾病的新方法和试剂盒。 本发明还涉及自身免疫性疾病如多发性硬化的治疗，以及在包含以大于24小时的间隔施用的制剂的治疗方案中施用无规共聚物，或者涉及在一段时间内施用共聚物的持续释放制剂 超过24小时。 本发明还涉及用于进行药物业务的方法，其包括制造，许可或分发包含本文所述的无规共聚物的制剂或给药方案的试剂盒。

公开(公告)号：US20130085393A1

公开(公告)日：2013-04-04

申请号：US13702254

申请日：2011-04-27

Applicant: Michael Schauf ,  Keith Johnson

Inventor： Michael Schauf ,  Keith Johnson

IPC: A61B8/00 ,  A61B8/08 ,  A61B8/02 ,  A61B8/14

CPC classification number: A61B8/543 ,  A61B8/02 ,  A61B8/0866 ,  A61B8/0883 ,  A61B8/14 ,  A61B8/145 ,  A61B8/4405 ,  A61B8/4488 ,  A61B8/466 ,  A61B8/469 ,  A61B8/483 ,  A61B8/5223 ,  G01S7/52073 ,  G01S7/52074 ,  G01S15/8993

Abstract: An ultrasound system and method provide a workflow to acquire 3D images of the fetal heart gated by a synthetic heart gating signal. An ROI is defined in an ultrasound image which delineates the fetal heart. The ultrasound system is controlled to automatically estimate the fetal heart rate from echo signals received from the ROI. When the system has acquired a stable synthetic heart rate signal, an indication thereof is given to the user and the user then commands the system to acquire 3D fetal heart images for a number of fetal heart cycles which are gated using the synthetic heart rate signal.

Abstract translation: 超声系统和方法提供了通过合成心脏门控信号获取胎心的3D图像的工作流程。 在描绘胎儿心脏的超声图像中定义ROI。 控制超声系统以从从ROI接收到的回波信号自动估计胎心率。 当系统已经获得稳定的合成心率信号时，向用户给出指示，然后用户命令系统获取使用合成心率信号门控的多个胎儿心脏周期的3D胎儿心脏图像。

公开(公告)号：US07862209B2

公开(公告)日：2011-01-04

申请号：US11971718

申请日：2008-01-09

Applicant: James J. Fitzgibbon ,  Keith Johnson ,  David Thomas Mack ,  Robert J. Olmsted

Inventor： James J. Fitzgibbon ,  Keith Johnson ,  David Thomas Mack ,  Robert J. Olmsted

IPC: F21V29/00

CPC classification number: E05F15/668 ,  E05Y2800/106 ,  E05Y2900/106

Abstract: A barrier movement operator controls movement of a movable barrier. The barrier movement operator includes a head unit, including a chassis, for commanding the movable barrier to perform movable barrier functions. A plurality of closely mounted light emitting elements are fixedly mounted onto the head unit. A heat sink is in thermal communication with the set of light emitting elements and with the chassis of the barrier movement operator to dissipate thermal energy from the set of light emitting elements. A controller is utilized for controlling the head unit to provide power to the set of light emitting elements.

Abstract translation: 屏障运动操作者控制可移动屏障的移动。 障碍运动操作者包括一个头单元，包括底盘，用于指示可动挡板执行可移动的屏障功能。 多个紧密安装的发光元件固定地安装在头单元上。 散热器与该组发光元件和屏障移动操作器的底座热连通以从该组发光元件散发热能。 控制器用于控制头单元以向该组发光元件提供电力。

公开(公告)号：US20100105734A1

公开(公告)日：2010-04-29

申请号：US12317575

申请日：2008-12-24

Applicant: A.K. Gunnar Aberg ,  Keith Johnson

Inventor： A.K. Gunnar Aberg ,  Keith Johnson

IPC: A61K31/4535 ,  A61P27/02

CPC classification number: A61K31/4535

Abstract: Methods of using a cycloheptathiophene compound for the treatment of xerophthalmia are described, as are formulations and compositions for such treatment.

Abstract translation: 描述了使用环庚噻吩化合物治疗干眼症的方法，以及用于这种治疗的制剂和组合物。

公开(公告)号：US20090300702A1

公开(公告)日：2009-12-03

申请号：US12534915

申请日：2009-08-04

Applicant: Keith Johnson ,  Amol Mandelkar

Inventor： Keith Johnson ,  Amol Mandelkar

IPC: H04N7/173

CPC classification number: H04N21/6473 ,  H04L41/0659 ,  H04L43/0811 ,  H04L43/0817 ,  H04N21/6118 ,  H04N21/6168 ,  H04N21/6338 ,  H04N21/64322

Abstract: A system and method for determining an operational status of a segment of a hybrid fiber coax (HFC) cable network. Subscriber premises units (SPUs) connected to the HFC cable network are “pinged” and their responses recorded. The two most responsive SPUs in each node of the HFC cable network are identified. The most responsive SPU is added to a primary ping list and the next most responsive SPU is added to a secondary ping list. The SPUs on the primary list are “pinged” and their responses recorded. If an SPU on the primary list fails to respond, the secondary SPU associated with the node is pinged. If both the primary and secondary SPU associated with a node fail to respond to the “ping,” the node is identified as non-responsive. If all of the nodes associated with a modulator (or a demodulator) are identified as non-responsive, the modulator (or demodulator) is identified as “non-responsive.” Additionally, network devices are pinged and their responses noted. Using the responsiveness of nodes and network devices, faults in segments in an HFC cable network can be identified and located.

Abstract translation: 一种用于确定混合光纤同轴电缆（HFC）电缆网络的段的操作状态的系统和方法。 连接到HFC电缆网络的用户位置单元（SPU）被“ping”并记录其响应。 识别HFC电缆网络每个节点中最响应的两个SPU。 最响应的SPU被添加到主ping列表中，并且下一个最响应的SPU被添加到辅助ping列表。 主要列表上的SPU被“ping”并记录其响应。 如果主列表中的SPU无法响应，则与该节点关联的辅助SPU被ping通。 如果与节点相关联的主SPU和辅助SPU都无法响应“ping”，则节点被识别为无响应。 如果与调制器（或解调器）相关联的所有节点被识别为非响应，则调制器（或解调器）被识别为“无响应”。 此外，网络设备被ping通，并且其响应被注意到。 使用节点和网络设备的响应能力，可以识别和定位HFC网络中段的故障。

公开(公告)号：US20090175025A1

公开(公告)日：2009-07-09

申请号：US11971718

申请日：2008-01-09

Applicant: James J. Fitzgibbon ,  Keith Johnson ,  David Thomas Mack ,  Robert J. Olmsted

Inventor： James J. Fitzgibbon ,  Keith Johnson ,  David Thomas Mack ,  Robert J. Olmsted

IPC: F21V33/00

CPC classification number: E05F15/668 ,  E05Y2800/106 ,  E05Y2900/106

Abstract: A barrier movement operator controls movement of a movable barrier. The barrier movement operator includes a head unit, including a chassis, for commanding the movable barrier to perform movable barrier functions. A plurality of closely mounted light emitting elements are fixedly mounted onto the head unit. A heat sink is in thermal communication with the set of light emitting elements and with the chassis of the barrier movement operator to dissipate thermal energy from the set of light emitting elements. A controller is utilized for controlling the head unit to provide power to the set of light emitting elements.

Abstract translation: 屏障运动操作者控制可移动屏障的移动。 障碍运动操作者包括一个头单元，包括底盘，用于指示可动挡板执行可移动的屏障功能。 多个紧密安装的发光元件固定地安装在头单元上。 散热器与该组发光元件和屏障移动操作器的底座热连通以从该组发光元件散发热能。 控制器用于控制头单元以向该组发光元件提供电力。

公开(公告)号：US20070044795A1

公开(公告)日：2007-03-01

申请号：US11494764

申请日：2006-07-26

Applicant: Robert Casper ,  Keith Johnson ,  David Gardner

Inventor： Robert Casper ,  Keith Johnson ,  David Gardner

IPC: A61M15/00

CPC classification number: B65D81/3261 ,  A61J1/035 ,  A61M15/0003 ,  A61M15/0045 ,  A61M15/0048 ,  A61M2202/064

Abstract: An apparatus and method for delivering a plurality of medication includes providing first and second medicament on a medicament pack in separate containers for preventing either medicament from interfering with the stability of the other. In accordance with the method, the medicaments are preferably delivered in a single inhalation.

公开(公告)号：US20060219382A1

公开(公告)日：2006-10-05

申请号：US11097420

申请日：2005-04-01

Applicant: Keith Johnson ,  Duane Johnson

Inventor： Keith Johnson ,  Duane Johnson

IPC: B60H1/00

CPC classification number: B60H1/00757

Abstract: A control system for disabling the fan of a heating, ventilating, and air-conditioning system upon the detection of an audible alarm, such as a smoke alarm. The preferred embodiment utilizes a tunable band pass filter/decibel level detector in conjunction with a microphone to detect an audible alarm. When an alarm is detected, the fan is disabled whether the HVAC is operating in heating, cooling, or manual fan “on” mode.

公开(公告)号：US20060218612A1

公开(公告)日：2006-09-28

申请号：US11069156

申请日：2005-03-01

Applicant: Keith Johnson ,  Amol Mandlekar

Inventor： Keith Johnson ,  Amol Mandlekar

IPC: H04N7/173

CPC classification number: H04N21/6118 ,  H04L43/0817 ,  H04L43/10 ,  H04L43/16 ,  H04N21/2543 ,  H04N21/6168 ,  H04N21/6338 ,  H04N21/6473

Abstract: A fault detection and isolation system for an HFC cable network and method therefore. A ping list generator captures set top box (STB) identifying information from a billing system, and STB state information from a network control system. The ping list generator creates a ping list from the STB identifying information and the STB state information, wherein the list comprises the IP address of a set of the addressable STBs connected to an HFC cable network. In an exemplary embodiment, the set is of sufficient size to be representative of the health of the HFC cable network. In another embodiment of the present invention, the set comprises substantially all of the addressable STBs connected to the HFC cable network. A ping generator, pings the IP address of the STB and awaits a response. If the response is received from the STB, then identify the STB as responsive. If the response is not received, then identify the STB as non-responsive. A fault isolation processor associates the STB identifying information and the ping response, determines whether a non-responsive fault indicator is present, and, if the fault indicator is present, then identifies a likely cause of the non-responsive fault.

Abstract translation: 一种用于HFC电缆网络的故障检测和隔离系统及方法。 ping列表生成器捕获来自计费系统的机顶盒（STB）识别信息，以及来自网络控制系统的STB状态信息。 ping列表生成器从STB识别信息和STB状态信息创建ping列表，其中列表包括连接到HFC电缆网络的一组可寻址STB的IP地址。 在示例性实施例中，该组具有足够的尺寸以代表HFC电缆网络的健康。 在本发明的另一个实施例中，该组包括连接到HFC电缆网络的基本上所有可寻址STB。 ping生成器，ping STB的IP地址，并等待响应。 如果从STB接收到响应，则将STB识别为响应。 如果没有收到响应，则将STB识别为无响应。 故障隔离处理器将STB识别信息和ping响应相关联，确定是否存在无响应故障指示符，并且如果存在故障指示符，则识别出无响应故障的可能原因。

公开(公告)号：US20060194725A1

公开(公告)日：2006-08-31

申请号：US11283405

申请日：2005-11-17

Applicant: James Rasmussen ,  Jianxin Zhang ,  Sam Baldwin ,  Eric Zanelli ,  Bei Yu ,  Dustan Bonnin ,  Keith Johnson ,  Jeff Krieger

Inventor： James Rasmussen ,  Jianxin Zhang ,  Sam Baldwin ,  Eric Zanelli ,  Bei Yu ,  Dustan Bonnin ,  Keith Johnson ,  Jeff Krieger

IPC: A61K38/17

CPC classification number: C07K14/435 ,  A61K9/0019 ,  A61K31/785 ,  A61K38/02

Abstract: The invention relates to novel methods and kits for treating or preventing disease through the administration of random copolymers. The invention also relates to the treatment of autoimmune diseases, such as multiple sclerosis, and to the administration of random copolymers in treatment regimen comprising formulations that are administered at intervals greater than 24 hours, or to sustained release formulations which administer the copolymer over a period greater than 24 hours. The invention further relates to methods for conducting a pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the formulations or dosing regimens of random copolymer described herein.

Abstract translation: 本发明涉及通过施用无规共聚物治疗或预防疾病的新方法和试剂盒。 本发明还涉及自身免疫性疾病如多发性硬化的治疗，以及在包含以大于24小时的间隔施用的制剂的治疗方案中施用无规共聚物，或者涉及在一段时间内施用共聚物的持续释放制剂 超过24小时。 本发明还涉及用于进行药物业务的方法，其包括制造，许可或分发包含本文所述的无规共聚物的制剂或给药方案的试剂盒。