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61.发明申请公开(公告)号：US20050042670A1
公开(公告)日：2005-02-24
申请号：US10954110
申请日：2004-09-30
CPC分类号： C12N9/6424
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the protease peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the protease peptides, and methods of identifying modulators of the protease peptides.
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62.发明申请公开(公告)号：US20050089897A1
公开(公告)日：2005-04-28
申请号：US10924786
申请日：2004-08-25
申请人： Chunhua Yan , Ming-Hui Wei , Karen Ketchum , Gennady Merkulov , Ellen Beasley
发明人： Chunhua Yan , Ming-Hui Wei , Karen Ketchum , Gennady Merkulov , Ellen Beasley
IPC分类号： A01K67/027 , A61K38/00 , A61K45/00 , A61P9/10 , A61P17/06 , A61P29/00 , A61P35/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/09 , C12N15/54 , C12Q1/02 , C12Q1/48 , C12Q1/68 , C07H21/04
CPC分类号： C12N9/1205 , A01K2217/05 , A61K38/00
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
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63.发明申请公开(公告)号：US20050164291A1
公开(公告)日：2005-07-28
申请号：US11084749
申请日：2005-03-21
申请人： Zhenya Li , Ming-Hui Wei , Karen Ketchum , Ellen Beasley
发明人： Zhenya Li , Ming-Hui Wei , Karen Ketchum , Ellen Beasley
IPC分类号： A01K67/027 , A61K45/00 , A61P43/00 , C07K14/705 , C07K16/40 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/16 , C12N15/09 , C12N15/55 , C12Q1/02 , C12Q1/68 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号： C07K14/705
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
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64.发明申请公开(公告)号：US20050158312A1
公开(公告)日：2005-07-21
申请号：US11014035
申请日：2004-12-17
IPC分类号： C07K14/705 , C12N1/21 , C12N15/12 , C12Q1/68 , A61K39/395 , C07H21/04 , C07K16/28
CPC分类号： C07K14/705
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
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65.发明申请公开(公告)号：US20060051850A1
公开(公告)日：2006-03-09
申请号：US10472808
申请日：2002-01-17
申请人： Chunhua Yan , Zhenya Li , Karen Ketchum , Ellen Beasley
发明人： Chunhua Yan , Zhenya Li , Karen Ketchum , Ellen Beasley
IPC分类号： C07H21/04 , C12P21/06 , C12N9/00 , C07K14/705 , C07K16/28
CPC分类号： C07K14/705 , C07K14/47
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
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66.发明申请Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof 有权与牛皮癣相关的遗传多态性，检测方法及其用途公开(公告)号：US20080108713A1
公开(公告)日：2008-05-08
申请号：US11899017
申请日：2007-08-31
申请人： Ann Begovich , Ellen Beasley , Michele Cargill , Steven Schrodi
发明人： Ann Begovich , Ellen Beasley , Michele Cargill , Steven Schrodi
IPC分类号： A61K47/00 , A61P43/00 , C12Q1/68 , G01N33/566
CPC分类号： C12Q1/6883 , A61K31/5377 , C07K16/244 , C07K2317/21 , C07K2317/24 , C07K2317/76 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , G01N33/6893 , G01N2500/04 , G01N2800/205
摘要： The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
摘要翻译： 本发明基于与牛皮癣和相关病理学相关的遗传多态性的发现。 具体地，本发明涉及含有多态性的核酸分子，包括可用作签名标记组的核酸分子的基团，例如单倍型，外来型，由该核酸分子编码的变体蛋白，用于 检测多态性核酸分子和蛋白质，以及使用核酸和蛋白质的方法以及使用试剂进行检测的方法。
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67.发明申请公开(公告)号：US20050227284A1
公开(公告)日：2005-10-13
申请号：US11143787
申请日：2005-06-03
申请人： Beena Neelam , Natalia Milshina , Chunhua Yan , Valentina Difrancesco , Ellen Beasley , Karen Ketchum
发明人： Beena Neelam , Natalia Milshina , Chunhua Yan , Valentina Difrancesco , Ellen Beasley , Karen Ketchum
CPC分类号： C12N9/1205 , A01K2217/05
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
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68.发明申请Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof 审中-公开分离的人磷酸酶蛋白，编码人磷酸酶蛋白的核酸分子及其用途公开(公告)号：US20050169905A1
公开(公告)日：2005-08-04
申请号：US10732453
申请日：2003-12-11
申请人： Chunhua Yan , Weiniu Gan , Valentina Francesco , Ellen Beasley
发明人： Chunhua Yan , Weiniu Gan , Valentina Francesco , Ellen Beasley
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphatase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphatase peptides, and methods of identifying modulators of the phosphatase peptides.
摘要翻译： 本发明提供由人类基因组内的基因编码的肽的氨基酸序列，本发明的磷酸酶肽。 本发明特别提供分离的肽和核酸分子，鉴定磷酸酶多肽的直向同源物和旁系同源物的方法，以及鉴定磷酸酶多肽调节剂的方法。
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69.发明申请Isolated human dehydrogenase proteins, nucleic acid molecules encoding these human dehydrogenase proteins, and uses thereof 审中-公开分离的人脱氢酶蛋白，编码这些人脱氢酶蛋白的核酸分子及其用途公开(公告)号：US20050158776A1
公开(公告)日：2005-07-21
申请号：US11023805
申请日：2004-12-29
申请人： Chunhua Yan , Zhenya Li , Gennady Merkulov , Valentina Francesco , Ellen Beasley
发明人： Chunhua Yan , Zhenya Li , Gennady Merkulov , Valentina Francesco , Ellen Beasley
CPC分类号： C12N9/0006 , A01K2217/05 , A61K38/00
摘要： The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the dehydrogenase polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the dehydrogenase polypeptides, and methods of identifying modulators of the dehydrogenase polypeptides.
摘要翻译： 本发明提供由人基因组内的基因，本发明的脱氢酶多肽编码的多肽的氨基酸序列。 本发明具体提供分离的多肽和核酸分子，鉴定脱氢酶多肽的直向同源物和旁系同源物的方法，以及鉴定脱氢酶多肽的调节剂的方法。
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公开(公告)号：US07993833B2
公开(公告)日：2011-08-09
申请号：US11899017
申请日：2007-08-31
申请人： Ann Begovich , Ellen Beasley , Michele Cargill , Steven Schrodi
发明人： Ann Begovich , Ellen Beasley , Michele Cargill , Steven Schrodi
CPC分类号： C12Q1/6883 , A61K31/5377 , C07K16/244 , C07K2317/21 , C07K2317/24 , C07K2317/76 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , G01N33/6893 , G01N2500/04 , G01N2800/205
摘要： The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
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