公开(公告)号：US20110040345A1

公开(公告)日：2011-02-17

申请号：US12637596

申请日：2009-12-14

申请人： Brian Jeffrey Wenzel ,  Timothy A. Fayram ,  Allen J. Keel ,  Edward Karst ,  Wenbo Hou ,  Taraneh Ghaffari Farazi

发明人： Brian Jeffrey Wenzel ,  Timothy A. Fayram ,  Allen J. Keel ,  Edward Karst ,  Wenbo Hou ,  Taraneh Ghaffari Farazi

IPC分类号： A61N1/365

CPC分类号： A61N1/36585 ,  A61B5/02125 ,  A61B5/0215 ,  A61B5/0295 ,  A61B5/0535 ,  A61B5/1459 ,  A61B5/7239 ,  A61N1/08 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/0002

摘要： Provided herein are implantable systems, and methods for use therewith, for monitoring a patient's electromechanical delay (EMD). Paced cardiac events are caused by delivering sufficient pacing stimulation to cause capture to the patient's heart. A cardiogenic impedance (CI) signal, indicative of cardiac contractile activity in response to the pacing stimulation being delivered, is obtained. One or more predetermined features of the CI signal are detected, and a value indicative of the patient's EMD is determined by determining a time between a delivered pacing stimulation and at least one of the detected one or more features of the CI signal.

摘要翻译： 本文提供了可植入系统及其使用的方法，用于监测患者的机电延迟（EMD）。 节奏心脏事件是通过提供足够的起搏刺激来引起对患者心脏的捕获而引起的。 获得指示响应于起搏刺激被递送的心脏收缩活动的心源阻抗（CI）信号。 检测CI信号的一个或多个预定特征，并且通过确定发出的起搏刺激与检测到的CI信号的一个或多个特征中的至少一个之间的时间来确定指示患者的EMD的值。

公开(公告)号：US20100312128A1

公开(公告)日：2010-12-09

申请号：US12648595

申请日：2009-12-29

申请人： Edward Karst ,  Brian Jeffrey Wenzel ,  Allen J. Keel ,  Wenbo Hou ,  Taraneh Ghaffari Farazi

发明人： Edward Karst ,  Brian Jeffrey Wenzel ,  Allen J. Keel ,  Wenbo Hou ,  Taraneh Ghaffari Farazi

IPC分类号： A61B5/0265

CPC分类号： A61B5/026 ,  A61B5/0261 ,  A61B5/0265 ,  A61B5/0295 ,  A61B5/0535 ,  A61B5/201 ,  A61B5/412 ,  A61B5/6846 ,  A61B8/06 ,  A61B8/12 ,  A61B8/4472 ,  A61N1/365 ,  A61N1/3702

摘要： Methods and systems for monitoring an organ of interest within a patient use one or more sensors to obtain one or more signals indicative of one or more of blood being provided to the organ of interest, blood being received from the organ of interest, and blood present in the organ of interest. Changes in an amount of blood being provided to the organ of interest, an amount of blood being received from the organ of interest, and/or an amount of blood present in the organ of interest are monitored based on changes in the obtained signal(s). Such methods and systems can be used to detect dysfunction of the organ of interest or tumor growth in the organ of interest, but are not limited thereto.

摘要翻译： 用于监测患者感兴趣的器官的方法和系统使用一个或多个传感器来获得指示一个或多个指示感兴趣器官的血液的信号，从感兴趣的器官接收的血液和血液存在的一个或多个信号 在感兴趣的机关。 根据所获得的信号（s）的变化来监视提供给感兴趣器官的血液量的变化，从感兴趣的器官接收的血液的量和/或存在于感兴趣的器官中的血液的量 ）。 这些方法和系统可用于检测感兴趣器官的感兴趣器官或肿瘤生长的功能障碍，但不限于此。