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公开(公告)号:US20210025025A1
公开(公告)日:2021-01-28
申请号:US16523970
申请日:2019-07-26
申请人: W. Davis Lee , Mark R. Amato
发明人: W. Davis Lee , Mark R. Amato
摘要: The invention comprises an apparatus and method of use thereof for generating a rare earth from a rare earth oxide, comprising the steps of: (1) dissociating the rare earth oxide and hydrogen gas in a reaction chamber by inductively heating the reaction chamber to greater than 2000° K to form the associated rare earth and water vapor in a reaction process; (2) driving the reaction process forward by removing the water vapor from the reaction chamber by condensing and freezing the water vapor on a first cold trap surface as water ice, where the reaction comprises: RE2O3+3H2→2RE+3H2O, where REO is a rare earth oxide and RE comprises a rare earth in the rare earth oxide; and/or (3) monitoring the reaction process by monitoring generation of at least one of the rare earth and the water in a control system designed for continuous/semi-continuous operation.
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公开(公告)号:US10684380B2
公开(公告)日:2020-06-16
申请号:US15240974
申请日:2016-08-18
申请人: W. Davis Lee , Mark R. Amato
发明人: W. Davis Lee , Mark R. Amato
摘要: Generally, a method or apparatus for tomographically imaging a sample, such as a tumor of a patient, using positively charged particles positions n two-dimensional detector arrays on n surfaces of a scintillation material or scintillator, respectively. Resultant from energy transfer from the positively charged particles, secondary photons are emitted from the scintillation material and detected by the plurality of two-dimensional detector arrays, where each detector array images the scintillation material. Combining signals from the plurality of two-dimensional detector arrays, the path, position, energy, and/or state of the positively charged particle beam as a function of time and/or rotation of the patient relative to the positively charged particle beam is determined and used in tomographic reconstruction of an image of the sample or the tumor.
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63.
公开(公告)号:US20200038681A1
公开(公告)日:2020-02-06
申请号:US16601592
申请日:2019-10-15
申请人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
发明人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
摘要: The invention comprises a method and apparatus for scanning charged particles in a cancer therapy system, comprising the steps of: (1) providing a first and second dipole magnet system and a gap, the gap comprising a common gap length, along a path of the charged particles, within both the first and second dipole magnet systems, the gap comprising a progressively increasing x/y-plane cross-section area from an entrance area of the charged particles into the double dipole magnet system to an exit area of the double dipole magnet system, the x/y-plane perpendicular to a z-axis from a center of the entrance area to a center of the exit area; (2) scanning the positively charged particles along a first axis of the x/y-plane using the first dipole magnet system; and (3) scanning the positively charged particles along a second axis of the x/y-plane using the second dipole magnet system.
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64.
公开(公告)号:US10518109B2
公开(公告)日:2019-12-31
申请号:US15459854
申请日:2017-03-15
申请人: Jillian Reno , Susan L. Michaud , Nick Ruebel , Mark R. Amato , W. Davis Lee , James P. Bennett
发明人: Jillian Reno , Susan L. Michaud , Nick Ruebel , Mark R. Amato , W. Davis Lee , James P. Bennett
摘要: The invention comprises a method and apparatus for determining a radiation beam treatment path to a tumor, comprising the steps of: (1) delivering charged particles from an accelerator, along a first beam transport path, through an output nozzle, and along a treatment path to the tumor relative to a calibrated reference beam path from the output nozzle toward a patient position and (2) prior to the step of delivering, a main controller verifying an unobstructed linear path of the treatment path using a set of fiducial indicators positioned at least: on a first element physically affixed and co-movable with the output nozzle and on a moveable object in the treatment room. Optionally, voxels of the treatment beam path and potentially obstructing objects are defined in the treatment room using an axis system relative to the calibrated reference beam path and a reference beam point.
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公开(公告)号:US20190351259A1
公开(公告)日:2019-11-21
申请号:US16526868
申请日:2019-07-30
申请人: W. Davis Lee , Mark R. Amato
发明人: W. Davis Lee , Mark R. Amato
摘要: The invention comprises a method and apparatus for reducing a kinetic energy of positively charged particles, comprising the steps of: (1) transporting the positively charged particles from an accelerator into an exit nozzle system along a beam line; (2) providing a first chamber of the exit nozzle system, the first chamber comprising: an incident side comprising an incident aperture, an exit side comprising an exit aperture, and a beam path of the positively charged particles from the incident aperture to the exit aperture; (3) filling the beam path in the chamber with a liquid; and (4) using the liquid to reduce the kinetic energy of the positively charged particles. The kinetic energy dissipater is optionally used in combination with a proton therapy cancer treatment system and/or a proton tomography imaging system.
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66.
公开(公告)号:US20190351258A1
公开(公告)日:2019-11-21
申请号:US16526978
申请日:2019-07-30
申请人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
发明人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
摘要: The invention comprises a method and apparatus for steering/scanning charged particles, comprising: a double dipole scanning system, comprising: (1) a beam path chamber comprising an entrance side and an exit side, the entrance side comprising a smaller area than the exit side; (2) a first dipole magnet, the first dipole magnet comprising a first coil and a third coil on first opposite sides of the beam path chamber; and (3) a second dipole magnet, the second dipole magnet comprising a second coil and a fourth coil on second opposite sides of the beam path chamber, the beam path chamber further comprising a truncated square/rectangle pyramid shape, the smaller entrance side of the charged particles comprising a top of the truncated pyramid shape, the exit side of the charged particles comprising a larger bottom of the truncated pyramid shape.
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公开(公告)号:US10279198B2
公开(公告)日:2019-05-07
申请号:US15868966
申请日:2018-01-11
摘要: A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.
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公开(公告)号:US10213624B2
公开(公告)日:2019-02-26
申请号:US15705437
申请日:2017-09-15
申请人: W. Davis Lee , Mark R. Amato , Susan L. Michaud
发明人: W. Davis Lee , Mark R. Amato , Susan L. Michaud
摘要: The invention comprises a method and apparatus for tracking and/or imaging impact of a particle beam treating a tumor using one or more imaging systems positionable about the tumor, such as a positron emission tracking and/or imaging system, where resulting tracking/imaging data: dynamically determines a treatment beam position, tracks a history of treatment beam positions, guides the treatment beam, and/or images a tumor before, during, and/or after treatment with the charged particle beam.
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公开(公告)号:US20180133512A1
公开(公告)日:2018-05-17
申请号:US15868966
申请日:2018-01-11
CPC分类号: A61N5/1069 , A61B6/03 , A61B6/032 , A61B6/0457 , A61B6/4014 , A61B6/4092 , A61B6/4258 , A61B6/4266 , A61B6/4417 , A61B6/4435 , A61B6/5205 , A61B6/5247 , A61N5/1037 , A61N5/1039 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G01N23/046 , G01N2223/107 , G01N2223/203 , G21K1/093 , G21K5/04
摘要: A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.
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公开(公告)号:US20170113067A1
公开(公告)日:2017-04-27
申请号:US15402739
申请日:2017-01-10
申请人: W. Davis Lee , Mark R. Amato , Nick Ruebel , Jillian Reno , Susan L. Michaud
发明人: W. Davis Lee , Mark R. Amato , Nick Ruebel , Jillian Reno , Susan L. Michaud
IPC分类号: A61N5/10
CPC分类号: A61N5/1081 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/1051 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要: The invention comprises a fiducial marker—fiducial detector based treatment room position determination/positioning system apparatus and method of use thereof. A set of fiducial markers and fiducial detectors are used to mark/determine relative position of static and/or moveable objects in a treatment room using photons passing from the markers to the detectors. Further, position and orientation of at least one of the objects is calibrated to a reference line, such as a zero-offset beam treatment line passing through an exit nozzle, which yields a relative position of each fiducially marked object in the treatment room. Treatment calculations are subsequently determined using the reference line and/or points thereon. The treatment calculations are optionally and preferably performed without use of an isocenter point, such as a central point about which a treatment room gantry rotates, which eliminates mechanical errors associated with the isocenter point being an isocenter volume in practice.
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